C/EBPβ and CHOP participate in Tanshinone IIA-induced differentiation and apoptosis of acute promyelocytic leukemia cells in vitro

International Journal of Hematology

Volumn 92, Issue 4, 2010, Pages 571-578

  Zhang, Kaiji ^a   Li, Jian ^a   Meng, Wentong ^b   Xing, Hongyun ^b   Yang, Yiming ^a  

^a SICHUAN UNIVERSITY   (China)

^b SICHUAN UNIVERSITY   (China)

Author keywords

Apoptosis; C EBP ; CHOP; Differentiation; Tanshinone IIA

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN BETA; CD11B ANTIGEN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; RETINOIC ACID; SMALL INTERFERING RNA; TANSHINONE IIA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DIFFERENTIATION; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VITRO STUDY; LEUKEMIA CELL; PHARMACOLOGICAL BLOCKING; PROMYELOCYTIC LEUKEMIA; PROTEIN EXPRESSION; PROTEIN FUNCTION; REGULATORY MECHANISM;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; CCAAT-ENHANCER-BINDING PROTEIN-BETA; CELL DIFFERENTIATION; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LEUKEMIA, PROMYELOCYTIC, ACUTE; PHENANTHRENES; TRANSCRIPTION FACTOR CHOP;

EID: 78549263680     PISSN: 09255710     EISSN: None     Source Type: Journal    
DOI: 10.1007/s12185-010-0686-6     Document Type: Article

References (36)

1. H de The' C Chomienne M Lanotte L Degos A Dejean 1990 The t (15; 17) translocation of acute promyelocytic leukaemia fuses the retinoic acid receptor alpha gene to a novel transcribed locus Nature 347 558 561 10.1038/347558a0 (Pubitemid 20341546)
2. GQ Chen J Zhu XG Shi HJ Zhong GY Si XL Jin, et al. 1996 In vitro studies on cellular and molecular mechanisms of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia: As2O3 induces NB4 cell apoptosis with downregulation of Bcl-2 expression and modulation of PML-RAR alpha/PML proteins Blood 88 1052 1061 1:CAS:528:DyaK28Xks1Cjur0%3D 8704214
3. ME Huang YC Ye SR Chen JR Chai JX Lu L Zhoa, et al. 1988 Use of all-trans retinoic acid in the treatment of acute promyelocytic leukemia Blood 72 567 572 1:STN:280:DyaL1c3psVeisg%3D%3D 3165295
4. MA Sanz G Martin M Gonzalez A León C Rayón C Rivas, et al. 2004 Risk-adapted treatment of acute promyelocytic leukemia with all-trans-retinoic acid and anthracycline monochemotherapy: a multicenter study by the PETHEMA group Blood 103 1237 1243 1:CAS:528:DC%2BD2cXhsVSlt7g%3D 10.1182/blood-2003-07-2462 14576047 (Pubitemid 38168633)
5. V Mathews B George KM Lakshmi A Viswabandya A Bajel P Balasubramanian, et al. 2006 Single-agent arsenic trioxide in the treatment of newly diagnosed acute promyelocytic leukemia: durable remissions with minimal toxicity Blood 107 2627 2632 1:CAS:528:DC%2BD28XjtlKltbs%3D 10.1182/blood-2005-08-3532 16352810
6. YF Liu YM Zhu ZZ Shi JM Li L Wang Y Chen, et al. 2006 Long-term follow-up confirms the benefit of all-trans retinoic acid (ATRA) and arsenic trioxide (As2O3) as front line therapy for newly diagnosed acute promyelocytic leukemia Blood 108 170
7. S De Botton H Dombret M Sanz JS Miguel D Caillot R Zittoun, et al. 1992 Incidence, clinical features, and outcome of all trans-retinoid acid syndrome in 413 cases of newly diagnosed acute promyelocytic leukemia Blood 8 2712 2718
8. K Ohnishi H Yoshida K Shigeno S Nakamura S Fujisawa K Naito, et al. 2000 Prolongation of the QT Interval and Ventricular Tachycardia in Patients Treated with Arsenic Trioxide for Acute Promyelocytic Leukemia Ann Intern Med 133 881 885 1:CAS:528:DC%2BD3cXovVKjsr0%3D 11103058
9. QF Li SL Shi QR Liu J Tang J Song Y Liang 2008 Anticancer effects of ginsenoside Rg1, cinnamic acid, and tanshinone IIA in osteosarcoma MG-63 cells: nuclear matrix downregulation and cytoplasmic trafficking of nucleophosmin Int J Biochem Cell Biol 40 1918 1929 1:CAS:528:DC%2BD1cXnsF2mt7o%3D 10.1016/j.biocel.2008.01.031 18403247
10. CC Su YH Lin 2008 Tanshinone IIA down-regulates the protein expression of ErbB-2 and up-regulates TNF-alpha in colon cancer cells in vitro and in vivo Int J Mol Med 22 847 851 1:CAS:528:DC%2BD1MXks1Wjsw%3D%3D 19020785
11. AM Wang SH Sha W Lesniak J Schacht 2003 Tanshinone (Salviae miltiorrhizae extract) preparations attenuate aminoglycoside-induced free radical formation in vitro and ototoxicity in vivo Antimicrob Agents Chemother 47 1836 1841 1:CAS:528:DC%2BD3sXktlymtL4%3D 10.1128/AAC.47.6.1836-1841.2003 12760856 (Pubitemid 36637803)
12. Y Liu X Wang Y Liu 2003 Protective effects of tanshinone IIA on injured primary cultured rat hepatocytes induced by CCl4 Zhong Yao Cai 26 415 417 14528681
13. YM Yang SL Yuan T Liu 1999 Study on anti-leukemia effect of tanshinone IIA in vitro and in vivo to acute promyelocytic leukemia Blood 94 595
14. DP Ramji P Foka 2002 CCAAT/enhancer-binding proteins: structure, function and regulation Biochem J 365 561 575 1:CAS:528:DC%2BD3sXptFOhtbs%3D 12006103
15. TN Seagroves S Krnacik B Raught J Gay B Burgess-Beusse GJ Darlington, et al. 1998 C/EBP, but not C/EBP, is essential for ductal morphogenesis, lobuloalveolar proliferation, and functional differentiation in the mouse mammary gland Genes Dev 12 1917 1928 1:CAS:528:DyaK1cXktl2gtb0%3D 10.1101/gad.12.12.1917 9637692
16. LM Scott CI Civin P Roth AD Friedman 1992 A novel temporal expression pattern of three C/EBP family members in differentiating myelomonocytic cells Blood 80 1725 1735 1:STN:280:DyaK3s%2FgsVOhtg%3D%3D 1391942
17. S Gery DJ Park PT Vuong DY Chih N Lemp HP Koeffler 2004 Retinoid acid regulates C/EBP homologous protein expression (CHOP), which negatively regulates myeloid genes Blood 104 3911 3917 1:CAS:528:DC%2BD2cXhtFaju73I 10.1182/blood-2003-10-3688 15308577 (Pubitemid 39620138)
18. E Duprez K Wagner H Koch DG Tenen 2003 C/EBPβ: a major PML-RARA-responsive gene in retinoic acid-induced differentiation of APL cell EMBO J 22 5806 5816 1:CAS:528:DC%2BD3sXovVeksbs%3D 10.1093/emboj/cdg556 14592978 (Pubitemid 37408819)
19. H Yamaguchi HG Wang 2004 CHOP is involved in endoplasmic reticulum stress-induced apoptosis by enhancing DR5 expression in human carcinoma cells J Biol Chem 279 45495 45502 1:CAS:528:DC%2BD2cXovVCnsr4%3D 10.1074/jbc.M406933200 15322075 (Pubitemid 39491535)
20. G Tiscornia O Singer IM Verma 2006 Production and purification of lentiviral vectors Nat Protoc 1 241 245 1:CAS:528:DC%2BD28XhtFOitbvP 10.1038/nprot.2006.37 17406239
21. SY Sun X Liu W Zou P Yue AI Marcus FRT Khuri 2007 The farnesyltransferase inhibitor lonafarnib induces CCAAT/enhancer-binding protein homologous protein-dependent expression of death receptor 5, leading to induction of apoptosis in human cancer cells J Biol Chem 282 18800 18809 1:CAS:528: DC%2BD2sXmvVarsL0%3D 10.1074/jbc.M611438200 17493934 (Pubitemid 47100180)
22. PM Popermack LT Truong M Kamphuis AJ Henderson 2001 Ectopic expression of CCAAAT/enhancer binding proteinβ (C/EBPβ) in long-term bone marrow cultures induces granulopoiesis and alters stromal cell function J Hematother Stem Cell Res 10 631 642 10.1089/152581601753193841 (Pubitemid 32988613)
23. D Ron JF Habener 1992 CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription Genes Dev 6 439 453 1:CAS:528:DyaK3sXitVKksrc%3D 10.1101/gad.6.3.439 1547942
24. YJ Lee LC Jones NA Timchenko D Perrotti DG Tenen SC Kogan 2006 CCAAT/enhancer binding proteins alpha and epsilon cooperate with all-trans retinoic acid in therapy but differ in their antileukemic activities Blood 108 2416 2419 1:CAS:528:DC%2BD28XhtVCgurzJ 10.1182/blood-2006-02-003582 16788101 (Pubitemid 44497527)
25. W Ding YP Li LM Nobile G Grills I Carrera E Paietta, et al. 1998 Leukemic cellular retinoic acid resistance and missense mutations in the PML-RARα fusion gene after relapse of acute promyelocytic leukemia from treatment with all-trans retinoic acid and intensive chemotherapy Blood 92 1172 1183 1:CAS:528:DyaK1cXlsVWrsb4%3D 9694705
26. P Descombes U Schibler 1991 A liver-enriched transcriptional activator protein, LAP, and a transcriptional inhibitory protein, LIP, are translated from the same mRNA Cell 67 569 579 1:CAS:528:DyaK3MXmslansb8%3D 10.1016/0092- 8674(91)90531-3 1934061
27. CF Calkhoven C Muller A Leutz 2000 Translational control of C/EBPα and C/EBPβ isoform expression Genes Dev 14 1920 1932 1:CAS:528: DC%2BD3cXls1yqtrg%3D 10921906
28. CA Zahnow RD Cardiff R Laucirica D Medina JM Rosen 2001 A role for CCAAT/enhancer binding protein β-liver-enriched inhibitory protein in mammary epithelial cell proliferation Cancer Res 61 261 269 1:CAS:528: DC%2BD3MXlsl2rsQ%3D%3D 11196172
29. T Sakurai T Ohta K Fujiwara 2005 Inorganic arsenite alters macrophage generation from human peripheral blood monocytes Toxicol Appl Pharmacol 203 145 153 1:CAS:528:DC%2BD2MXhtlelsb4%3D 10.1016/j.taap.2004.08.003 15710175 (Pubitemid 40248370)
30. EH Kim MJ Yoon SU Kim TK Kwon S Sohn KS Choi 2008 Arsenic trioxide sensitizes human glioma cells, but not normal astrocytes, to TRAIL-induced apoptosis via CCAAT/enhancer-binding protein homologous protein-dependent DR5 up-regulation Cancer Res 68 266 275 1:CAS:528:DC%2BD1cXoslWh 10.1158/0008-5472.CAN-07-2444 18172319 (Pubitemid 351380128)
31. GQ Chen XG Shi W Tang SM Xiong J Zhu X Cai, et al. 1997 Use of arsenic trioxide (As2O3) in the treatment of acute promyelocytic leukemia (APL): I. As2O3 exerts dose-dependent dual effects on APL cell Blood 89 3345 3353 1:CAS:528:DyaK2sXivVymtbg%3D 9129041
32. H Schrem J Klempnauer J Borlak 2004 Liver-enriched transcription factors in liver function and development. Part II: The C/EBPs and D site-binding protein in cell cycle control, carcinogenesis, circadian gene regulation, liver regeneration, apoptosis, and liver-specific gene regulation Pharmacol Rev 56 291 330 1:CAS:528:DC%2BD2cXltlKgtbg%3D 10.1124/pr.56.2.5 15169930 (Pubitemid 38720832)
33. WP Cheng HF Hung BW Wang KG Shyu 2008 The molecular regulation of GADD153 in apoptosis of cultured vascular smooth muscle cells by cyclic mechanical stretch Cardiovasc Res 77 551 559 1:CAS:528:DC%2BD1cXjvVagsbY%3D 10.1093/cvr/cvm057 18006442 (Pubitemid 351197658)
34. L Altucci A Rossin W Raffelsberger A Reitmair C Chomienne H Gronemeyer 2001 Retinoic acid-induced apoptosis in leukemia cells is mediated by paracrine action of tumor-selective death ligand TRAIL Nat Med 7 680 686 1:CAS:528:DC%2BD3MXktlGkurY%3D 10.1038/89050 11385504 (Pubitemid 32588023)
35. WT Choi MR Folsom MF Azim, et al. 2007 C/EBPβ suppression by interruption of CUGBP1 resulting from a complex rearrangement of MLL Cancer Genet Cytogenet 177 2 108 114 1:CAS:528:DC%2BD2sXhtVCmtL%2FO 10.1016/j.cancergencyto.2007.07.002 17854664 (Pubitemid 47376898)
36. C Guerzoni M Bardini SA Mariani, et al. 2006 Inducible activation of CEBPB, a gene negatively regulated by BCR/ABL, inhibits proliferation and promotes differentiation of BCR/ABL-expressing cells Blood 107 10 4080 4099 1:CAS:528:DC%2BD28XkvFWgsrY%3D 10.1182/blood-2005-08-3181 16418324 (Pubitemid 43726817)