Tanshinone IIA induces apoptosis in human lung cancer A549 cells through the induction of reactive oxygen species and decreasing the mitochondrial membrane potential

International Journal of Molecular Medicine

Volumn 25, Issue 2, 2010, Pages 231-236

  Chiu, Tsung Lang ^a,c   Su, Chin Cheng ^b,c  

^a Institute of Medical Sciences   (Taiwan)

^b TZU CHI UNIVERSITY   (Taiwan)

^c BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

Author keywords

A549 cells; Apoptosis; Mitochondrial membrane potential; Reactive oxygen species; Tanshinone IIA

Indexed keywords

PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; REACTIVE OXYGEN METABOLITE; TANSHINONE IIA;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CANCER CELL; CELL CYCLE G1 PHASE; CELL GROWTH; CELL PROLIFERATION; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY TEST; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LUNG CANCER; LUNG NON SMALL CELL CANCER; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; BLOTTING, WESTERN; CALCIUM; CELL LINE, TUMOR; CELL SURVIVAL; CYTOCHROMES C; DNA FRAGMENTATION; HUMANS; LUNG NEOPLASMS; MEMBRANE POTENTIAL, MITOCHONDRIAL; PHENANTHRENES; PROTO-ONCOGENE PROTEINS C-BCL-2; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEIN P53;

EID: 73649126883     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm_00000335     Document Type: Article

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