Tanshinone IIA may inhibit the growth of small cell lung cancer H146 cells by up-regulating the Bax/Bcl-2 ratio and decreasing mitochondrial membrane potential

Molecular Medicine Reports

Volumn 3, Issue 4, 2010, Pages 645-650

  Cheng, Chun Yuan ^a,b   Su, Chin Cheng ^c,d  

^a CHUNG SHAN MEDICAL UNIVERSITY   (Taiwan)

^b CHANGHUA CHRISTIAN HOSPITAL   (Taiwan)

^c TZU CHI UNIVERSITY   (Taiwan)

^d BUDDHIST TZU CHI GENERAL HOSPITAL   (Taiwan)

Author keywords

Bax Bcl 2 ratio; H146 cells; Mitochondrial membrane potential; Reactive oxygen species; Tanshinone IIA

Indexed keywords

BETA ACTIN; CALCIUM ION; CALCIUM RELEASE ACTIVATED CALCIUM CHANNEL; CASPASE 3; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MATRIX METALLOPROTEINASE; PROTEIN BAX; PROTEIN BCL 2; REACTIVE OXYGEN METABOLITE; TANSHINONE IIA; TRANSCRIPTION FACTOR RELA;

ARTICLE; CALCIUM TRANSPORT; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; CONTROLLED STUDY; CYTOTOXICITY; DRUG EFFECT; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTER; HUMAN; HUMAN CELL; IN VITRO STUDY; LUNG SMALL CELL CANCER; MITOCHONDRIAL MEMBRANE POTENTIAL; NITROBLUE TETRAZOLIUM TEST; PROTEIN EXPRESSION; PROTO ONCOGENE; UPREGULATION; WESTERN BLOTTING;

EID: 77956671599     PISSN: 17912997     EISSN: 17913004     Source Type: Journal    
DOI: 10.3892/mmr_00000310     Document Type: Article

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