The biochemical role of the heat shock protein 90 chaperone complex in establishing human telomerase activity

Journal of Biological Chemistry

Volumn 281, Issue 29, 2006, Pages 19840-19848

  Keppler, Brian R ^a   Grady, Allen T ^a   Jarstfer, Michael B ^a  

^a UNIVERSITY OF NORTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEXATION; ENZYME INHIBITION; POLYPEPTIDES; PROTEINS; RNA; SYNTHESIS (CHEMICAL);

HETEROCOMPLEX; PRIMERS; RIBONUCLEOPROTEIN COMPLEX; TELOMERASE STRUCTURE;

ENZYME KINETICS;

CHAPERONE; GELDANAMYCIN; HEAT SHOCK PROTEIN 90; HEAT SHOCK PROTEIN 90 INHIBITOR; NOVOBIOCIN; PROTEIN P23; STEROID RECEPTOR; TELOMERASE;

ARTICLE; CATALYSIS; DRUG INHIBITION; DRUG MECHANISM; DRUG PROTEIN BINDING; ENZYME ACTIVITY; HUMAN; IN VITRO STUDY; IN VIVO STUDY; LIGAND BINDING; PRIORITY JOURNAL; TELOMERE;

BENZOQUINONES; CYSTEINE PROTEINASE INHIBITORS; DNA PRIMERS; DNA-BINDING PROTEINS; HSP90 HEAT-SHOCK PROTEINS; HUMANS; LACTAMS, MACROCYCLIC; MODELS, BIOLOGICAL; TELOMERASE; TRANSCRIPTION, GENETIC;

EID: 33746030307     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M511067200     Document Type: Article

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