In vitro cytotoxicity of Tanshinones isolated from Salvia miltiorrhiza Bunge against P388 lymphocytic leukemia cells

Phytomedicine

Volumn 10, Issue 8, 2003, Pages 682-685

  Mosaddik, M A ^a  

^a SOUTHERN CROSS UNIVERSITY   (Australia)

Author keywords

Cytotoxicity; P388 lymphocytic leukemia cell; Salvia miltiorrhiza Bunge; Tanshinones

Indexed keywords

CRYPTOTANSHINONE; DIHYDROTANSHINONE I; DITERPENE; SALVIA MILTIORRHIZA EXTRACT; TANSHINONE; TANSHINONE I; UNCLASSIFIED DRUG;

ARTICLE; CYTOTOXICITY; DOSE RESPONSE; DRUG ACTIVITY; DRUG ISOLATION; DRUG STRUCTURE; LEUKEMIA CELL; LYMPHATIC LEUKEMIA; PLANT; PLANT ROOT; PRIORITY JOURNAL; SALVIA MILTIORRHIZA; STRUCTURE ACTIVITY RELATION; TANSHINONE IIA;

LAMIACEAE; SALVIA; SALVIA MILTIORRHIZA;

EID: 0344197546     PISSN: 09447113     EISSN: None     Source Type: Journal    
DOI: 10.1078/0944-7113-00321     Document Type: Article

References (14)

1. Burits M, Asres K, Bucar F (2001) The antioxidant activity of the essential oils of Artemisia afra, Artemisia abyssinica and Juniperus procera. Phyto Res 15: 103-108
2. Chen XG, Li Y, Yan CH, Li LN, Han R (2001) Cancer chemopreventive activities of S-3-1, a synthetic derivative of tanshinone. J Asian Nat Prod Res 3: 63-75
3. Cree IA, Pazzagli M, Mini E, Mazzei T, Hunter EMM, Sutherland LA, Pinzani P, Gerli A, Andreotti PE (1995) Methotrexate chemosensitivity by ATP luminescence in human leukaemia cell lines and in breast cancer primary cultures. Anti-Cancer Drugs 6: 398-404
4. Cree IA, Andreotti PE (1997) Measurement of cytotoxicity of ATP-based luminesence assay in primary cell cultures and lines. Toxicology in Vitro 11: 553-556
5. Crouch SPM, Kozlowshi R, Slater KJ, Fletcher J (1993) The use of ATP bioluminescence as a measure of cell proliferation and cytotoxicity. J Immunol Methods 160: 81-88
6. Ikeshiro Y, Mase I, Tomita Y (1989) Abietane type diterpenes from Salvia miltiorrhiza. Phytochemistry 28: 3139-3141
7. Kangas L, Gronroos M, Nieminen AL (1984) Bioluminescence of cellular ATP: a new method for evaluation agents in vitro. Medical Biology 62: 338-443
8. Lee AR, Wu WL, Chang WL, Lin HC, King ML (1987) Isolation and bioactivity of new tanshinones. J Nat Prod 50: 157-160
9. Lee DS, Lee SH, Noh SH, Hong SD (1999) Antibacterial activities of cryptotanshinone and dihydrotanshinone I from a medicinal herb, Salvia miltiorrhiza Bunge. Biosci Biotechnol Biochem 63: 2236-2239
10. Lin HC, Chang L (2000) Diterpenoids from Salvia miltiorrhiza. Phytochemistry 53: 951-953
11. Liu J, Shen M, Ong CN (2000) Salvia miltiorrhiza inhibits cell growth and induces apoptosis in human hepatoma HepG(2). Cancer Lett 29: 85-93
12. Luo HW, Wu BJ, Wu MY, Yong ZG, Niwa M, Hirata Y (1985) Pigments from Salvia miltiorrhiza. Phytochemistry 24: 815-817
13. Petty RD, Sutherland LA, Hunter EM, Cree IA (1995) Comparison of MTT and ATP based assays for the measurement of viable cell number. J Bioluminescence and Chemiluminescence 10: 29-34
14. Ryu SY, Lee CO, Choi SU (1997) In vitro cytotoxicity of tanshinones from Salvia multiorrhiza. Planta Med 63: 339-342