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Bioorganic and Medicinal Chemistry Letters

Volumn 21, Issue 24, 2011, Pages 7474-7478

Ortho-Quinone tanshinones directly inhibit telomerase through an oxidative mechanism mediated by hydrogen peroxide

(5) Soares, Joana a Keppler, Brian R a Wang, Xihong a Lee, Kuo Hsiung a,b Jarstfer, Michael B a

a University of North Carolina (United States)

b CHINA MEDICAL UNIVERSITY (Taiwan)

Author keywords

Hydrogen peroxide; ortho Quinones; Reactive oxygen species; Tanshinones; Telomerase

Indexed keywords

CATALASE; CRYPTOTANSHINONE; HYDROGEN PEROXIDE; NEO TANSHINLACTONE; ORTHOQUINONE 9,10 PHENANTHRENEQUINONE; REACTIVE OXYGEN METABOLITE; TANSHINONE I; TANSHINONE IIA; TELOMERASE; TERPENOID DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; CARCINOGENESIS; DRUG MECHANISM; DRUG TARGETING; HUMAN; HUMAN CELL; UPREGULATION;

BENZOQUINONES; CATALASE; CELL LINE, TUMOR; DITERPENES, ABIETANE; DITHIOTHREITOL; ENZYME ACTIVATION; ENZYME INHIBITORS; HUMANS; HYDROGEN PEROXIDE; OXIDATION-REDUCTION; TELOMERASE;

BACTERIA (MICROORGANISMS);

EID: 81255208416 PISSN: 0960894X EISSN: 14643405 Source Type: Journal
DOI: 10.1016/j.bmcl.2011.09.112 Document Type: Article

Times cited : (18)

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