Simultaneous determination of tanshinone I, dihydrotanshinone I, tanshinone IIA and cryptotanshinone in rat plasma by liquid chromatography - Tandem mass spectrometry: Application to a pharmacokinetic study of a standardized fraction of Salvia miltiorrhiza, PF2401-SF

Biomedical Chromatography

Volumn 22, Issue 5, 2008, Pages 548-555

  Park, Eun Jeong ^a   Ji, Hye Young ^a   Kim, Nam Jin ^a   Song, Won Young ^a   Kim, Young Hoon ^a   Kim, Youn Chul ^a   Sohn, Dong Hwan ^a   Lee, Hye Suk ^a  

^a Wonkwang University   (South Korea)

Author keywords

Cryptotanshinone; Dihydrotanshinone I; LC MS MS; PF2401 SF; Pharmacokinetics; Rat plasma; Tanshinone I; Tanshinone IIA

Indexed keywords

BODY FLUIDS; ELECTROSPRAY IONIZATION; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; RATS;

CRYPTOTANSHINONE; DIHYDROTANSHINONE I; LC-MS-MS; LC.MS/MS; PF2401-SF; RAT PLASMA; TANSHINONE I; TANSHINONE IIA; TANSHINONES;

PHARMACOKINETICS;

AMMONIUM FORMATE; CRYPTOTANSHINONE; DIHYDROTANSHINONE I; METHANOL; PF 2401 SF; PF 2401SF; PLANT EXTRACT; SALVIA MILTIORRHIZA EXTRACT; TANSHINONE; TANSHINONE I; TANSHINONE IIA; TARIQUIDAR;

ANALYTICAL ERROR; ANIMAL EXPERIMENT; AREA UNDER THE CURVE; ARTICLE; BLOOD SAMPLING; COLUMN CHROMATOGRAPHY; CONTROLLED STUDY; CORRELATION COEFFICIENT; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG HALF LIFE; DRUG STRUCTURE; ELECTROSPRAY MASS SPECTROMETRY; ELUTION; LIQUID CHROMATOGRAPHY; LIQUID LIQUID EXTRACTION; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; QUALITY CONTROL; QUANTITATIVE ANALYSIS; RAT; SENSITIVITY ANALYSIS; STRUCTURE ANALYSIS; TANDEM MASS SPECTROMETRY;

RATTUS; SALVIA MILTIORRHIZA;

EID: 44249104231     PISSN: 02693879     EISSN: 10990801     Source Type: Journal    
DOI: 10.1002/bmc.968     Document Type: Article

References (30)