Structural diversity and protein engineering of the aminoacyl-tRNA Synthetases

Biochemistry

Volumn 51, Issue 44, 2012, Pages 8705-8729

  Perona, John J ^a,b   Hadd, Andrew ^b  

^a PORTLAND STATE UNIVERSITY   (United States)

^b OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; AMINOACYL-TRNA SYNTHETASES (AARS); CATALYTIC PROPERTIES; EVOLUTIONARY CONVERGENCE; GENERAL APPROACH; GENETIC CODE; GENETIC INFORMATION; GENETIC SELECTION; IN-VIVO; LIVING CELL; PROTEIN ENGINEERING; PROTEIN STRUCTURES; RATIONAL DESIGN; STRUCTURAL DIVERSITY; SYNTHETASES;

BIOCHEMICAL ENGINEERING; GENES; GENETIC ENGINEERING; PROTEINS; RNA; SUBSTRATES;

AMINO ACIDS;

AMINO ACID TRANSFER RNA LIGASE; TRANSFER RNA;

AMINO ACID SEQUENCE; ARTICLE; CATALYSIS; ENZYME MECHANISM; ENZYME SPECIFICITY; ENZYME STRUCTURE; GENETIC CODE; GENETIC SELECTION; HUMAN; MOLECULAR EVOLUTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN ENGINEERING; PROTEIN MOTIF; PROTEIN RNA BINDING;

AMINO ACIDS; AMINO ACYL-TRNA SYNTHETASES; CATALYSIS; CATALYTIC DOMAIN; ESCHERICHIA COLI; EVOLUTION, MOLECULAR; GENETIC CODE; MODELS, MOLECULAR; PROTEIN CONFORMATION; PROTEIN ENGINEERING; RNA, TRANSFER; SUBSTRATE SPECIFICITY;

EID: 84868529168     PISSN: 00062960     EISSN: 15204995     Source Type: Journal    
DOI: 10.1021/bi301180x     Document Type: Article

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