Amino acid discrimination by a class I aminoacyl-tRNA synthetase specified by negative determinants

Journal of Molecular Biology

Volumn 328, Issue 2, 2003, Pages 395-408

  Bullock, Timothy L ^a   Uter, Nathan ^a   Nissan, T Amar ^a   Perona, John J ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Electrostatics; Hydrogen bonding; Molecular evolution; QSI, 5 O N (L Glu)sulfamoyl adenosine; RS, tRNA synthetase; Substrate specificity; Water mediated interactions

Indexed keywords

ALPHA CARBOXYLATE; AMIDE; AMINO ACID; AMINO ACID TRANSFER RNA LIGASE; ARGININE; CARBOXYLIC ACID DERIVATIVE; GLUTAMIC ACID; OXYGEN; TRANSFER RNA; UNCLASSIFIED DRUG;

AMINO ACID ANALYSIS; ARTICLE; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME BINDING; ESCHERICHIA COLI; EUKARYOTE; HYDROGEN BOND; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN FOLDING;

ESCHERICHIA COLI; EUKARYOTA;

EID: 0037466332     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0022-2836(03)00305-X     Document Type: Article

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