Crystal structure of human wildtype and S581L-mutant glycyl-tRNA synthetase, an enzyme underlying distal spinal muscular atrophy

FEBS Letters

Volumn 581, Issue 16, 2007, Pages 2959-2964

  Cader, Muhammed Z ^a   Ren, Jingshan ^b   James, Paul A ^a   Bird, Louise E ^b   Talbot, Kevin ^a   Stammers, David K ^b  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

GARS; Motor neuron; SMA

Indexed keywords

GLYCINE; GLYCINE TRANSFER RNA LIGASE; TRANSFER RNA;

AMINOACYLATION; ANTICODON; ARTICLE; AUTOSOMAL DOMINANT DISORDER; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME STRUCTURE; GENE MUTATION; HUMAN; NERVE CELL DEGENERATION; NONHUMAN; PRIORITY JOURNAL; PROTEIN CONFORMATION; SPINAL MUSCULAR ATROPHY;

AMINO ACID SUBSTITUTION; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; DIMERIZATION; DISTAL MYOPATHIES; GLYCINE-TRNA LIGASE; HUMANS; LEUCINE; MODELS, MOLECULAR; MUSCULAR ATROPHY, SPINAL; MUTANT PROTEINS; MUTATION, MISSENSE; RNA-BINDING PROTEINS; SERINE; TRANSFER RNA AMINOACYLATION;

EID: 34250340882     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2007.05.046     Document Type: Article

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