The crystal structure of the ternary complex of T.thermophilus seryl-tRNA synthetase with tRNASer and a seryl-adenylate analogue reveals a conformational switch in the active site

EMBO Journal

Volumn 15, Issue 11, 1996, Pages 2834-2842

  Cusack, Stephen ^a   Yaremchuk, Anna ^a   Tukalo, Michael ^a  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (France)

Author keywords

Class II aminoacyl tRNA synthetase; Protein RNA recognition; Ring ring interaction seryl tRNA synthetase; X ray crystallography

Indexed keywords

THERMUS THERMOPHILUS;

ADENOSINE PHOSPHATE; RNA BINDING PROTEIN; SERINE DERIVATIVE; SERINE TRANSFER RNA; SERINE TRANSFER RNA LIGASE;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME SUBSTRATE COMPLEX; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; THERMUS THERMOPHILUS;

AMINO ACID SEQUENCE; BINDING SITES; CRYSTALLOGRAPHY, X-RAY; ESCHERICHIA COLI; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PROTEIN CONFORMATION; RNA, TRANSFER, SER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SERINE-TRNA LIGASE; THERMUS THERMOPHILUS;

EID: 0030011019     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1002/j.1460-2075.1996.tb00644.x     Document Type: Article

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