The structure of an AspRS-tRNAAsp complex reveals a tRNA-dependent control mechanism

EMBO Journal

Volumn 20, Issue 18, 2001, Pages 5290-5301

  Moulinier, L ^a   Eiler, S ^a   Eriani, G ^b   Gangloff, J ^b   Thierry, J C ^a   Gabriel, K ^c   McClain, W H ^c   Moras, D ^a  

^a INSTITUT DE GÉNÉTIQUE ET DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^b INSTITUT DE BIOLOGIE MOLÉCULAIRE ET CELLULAIRE   (France)

^c UNIVERSITY OF WISCONSIN MADISON   (United States)

Author keywords

Aminoacylation reaction; Crystal structure; Protein RNA recognition; Species specificity

Indexed keywords

ADENOSINE; AMINO ACID; AMINO ACID TRANSFER RNA LIGASE; AMINOACYL TRANSFER RNA; ASPARTIC ACID; DIMER; PROTEIN SUBUNIT;

AMINOACYLATION; ARTICLE; CRYSTAL STRUCTURE; ENZYME ACTIVE SITE; ENZYME STRUCTURE; ESCHERICHIA COLI; MOLECULAR RECOGNITION; NONHUMAN; PRIORITY JOURNAL; PROTEIN RNA BINDING; REGULATORY MECHANISM; RNA STRUCTURE; SACCHAROMYCES CEREVISIAE; SPECIES DIFFERENCE;

EID: 0035903548     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/20.18.5290     Document Type: Article

References (34)

1. Asp
2. Asp by aspartyl-tRNA synthetase
3. Crystallography and NMR system: A new software suite for macromolecular structure determination
4. The active site of yeast aspartyl-tRNA synthetase: Structural and functional aspects of the aminoacylation reaction
5. Collaborative computational project No. 4. The CCP4 suite: Programs from protein crystallography
6. Correlation of deformability at a tRNA recognition site and aminoacylation specificity
7. Crystallization of transfer ribonucleic acids
8. Molecular replacement: The method and its problems
9. Asp in E.coli-a snapshot of the second step
10. Aspartyl-tRNA synthetase from E.coli: Cloning and characterisation of the gene, homologies of its translated amino acid sequence with asparaginyl- and lysyl-tRNA synthetases
11. Role of dimerization in yeast aspartyl-tRNA synthetase and importance of the class II invariant proline
12. SETOR: Hardware lighted three-dimensional model representations of macromolecules
13. Three suppressor forms of bacteriophage T4 leucine transfer RNA
14. Plasmid systems to study RNA function in Escherichia coli
15. Asp and aspartyl-tRNA synthetase from yeast in high concentrations of ammonium sulphate
16. Improved methods for the building of protein models in electron density maps and the location of errors in these models
17. Evaluation of a single crystal X-ray diffraction from a position-sensitive detector
18. A peculiar property of aspartyl-tRNA synthetase from baker's yeast: Chemical modification of the protein by the enzymatically synthesized aminoacyl adenylate
19. PROCHECK: A program to check the stereochemical quality of protein structure
20. Asp acylation
21. Asp
22. Met expressed from a synthetic gene in vivo
23. Asp
24. Asp recognition mechanism differing from that of the yeast system
25. A rapid finite difference algorithm utilizing successive over-relaxation to solve the Poisson-Boltzmann equation
26. Synthesis and recognition of aspartyl-adenylate by Thermus thermophilus aspartyl-tRNA synthetase
27. Identity elements for specific aminoacylation of yeast tRNA(Asp) by cognate aspartyl-tRNA synthetase
28. Phe
29. Class II aminoacyl transfer RNA synthetases: Crystal structure of yeast aspartyl-tRNA synthetase complexed with tRNA(Asp)
30. Crystal structure of aspartyl-tRNA synthetase from Pyrococcus kodakaraensis KOD: Archaeon specificity and catalytic mechanism of adenylate formation
31. Accuracy of in vivo aminoacylation requires proper balance of tRNA and aminoacyl-tRNA synthetase
32. Frog-high-speed restraint-constraint refinement program for macromolecular structure
33. The G-U wobble base pair: A fundamental building block of RNA structure crucial to RNA function in diverse biological systems
34. Translational efficiency of transfer RNAs: Uses of an extended anticodon