Elimination of intracellularly residing Mycobacterium tuberculosis through targeting of host and bacterial signaling mechanisms

Expert Review of Anti-Infective Therapy

Volumn 10, Issue 9, 2012, Pages 1007-1022

  Jayachandran, Rajesh ^a   Scherr, Nicole ^a,b   Pieters, Jean ^a  

^a UNIVERSITY OF BASEL   (Switzerland)

^b SWISS TROPICAL AND PUBLIC HEALTH INSTITUTE   (Switzerland)

Author keywords

inhibitory compounds; intramacrophage survival; Mycobacterium tuberculosis; signaling mechanisms; virulence factors

Indexed keywords

AX 20017; CALCINEURIN; CORONIN 1; CYCLIC AMP; CYCLOSPORIN A; GAMMA INTERFERON; KHELLIN; PHOSPHATASE; PROTEASOME; PROTEASOME INHIBITOR; PROTEIN SAPM; PROTEIN SERINE THREONINE KINASE; PROTEIN SERINE THREONINE KINASE INHIBITOR; PROTEIN SERINE THREONINE PHOSPHATASE; PROTEIN TYROSINE KINASE A; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE A; PROTEIN TYROSINE PHOSPHATASE B; TACROLIMUS; UNCLASSIFIED DRUG; VIRULENCE FACTOR; VOLTAGE GATED CALCIUM CHANNEL; WITHANOLIDE;

BACTERIAL SECRETION SYSTEM; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; DRUG MECHANISM; DRUG POTENCY; DRUG RESEARCH; DRUG TARGETING; HOST PATHOGEN INTERACTION; HUMAN; LYSOSOME; MACROPHAGE ACTIVATION; MORTALITY; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOCYTOSIS; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PUBLIC HEALTH; REVIEW; SIGNAL TRANSDUCTION; TUBERCULOSIS;

ANTITUBERCULAR AGENTS; BACTERIAL PROTEINS; DRUG RESISTANCE, BACTERIAL; HUMANS; MACROPHAGES; MYCOBACTERIUM TUBERCULOSIS; SIGNAL TRANSDUCTION; VIRULENCE;

EID: 84868124097     PISSN: 14787210     EISSN: 17448336     Source Type: Journal    
DOI: 10.1586/eri.12.95     Document Type: Review

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