-
1
-
-
4444291069
-
Interplay between mycobacteria and host signalling pathways
-
Koul A, Herget T, Klebl B, Ullrich A (2004) Interplay between mycobacteria and host signalling pathways. Nat Rev Microbiol 2: 189-202.
-
(2004)
Nat Rev Microbiol
, vol.2
, pp. 189-202
-
-
Koul, A.1
Herget, T.2
Klebl, B.3
Ullrich, A.4
-
2
-
-
22344433602
-
Mycobacterium tuberculosis and the host response
-
Kaufmann SH, Cole ST, Mizrahi V, Rubin E, Nathan C (2005) Mycobacterium tuberculosis and the host response. J Exp Med 201: 1693-1697.
-
(2005)
J Exp Med
, vol.201
, pp. 1693-1697
-
-
Kaufmann, S.H.1
Cole, S.T.2
Mizrahi, V.3
Rubin, E.4
Nathan, C.5
-
3
-
-
0035064072
-
Immunology of tuberculosis
-
Flynn JL, Chan J (2001) Immunology of tuberculosis. Annu Rev Immunol 19: 93-129.
-
(2001)
Annu Rev Immunol
, vol.19
, pp. 93-129
-
-
Flynn, J.L.1
Chan, J.2
-
4
-
-
0032508046
-
Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence
-
Cole ST, Brosch R, Parkhill J, Garnier T, Churcher C, et al. (1998) Deciphering the biology of Mycobacterium tuberculosis from the complete genome sequence. Nature 393: 537-544.
-
(1998)
Nature
, vol.393
, pp. 537-544
-
-
Cole, S.T.1
Brosch, R.2
Parkhill, J.3
Garnier, T.4
Churcher, C.5
-
5
-
-
0042766347
-
The Mycobacterium tuberculosis 19-kilodalton lipoprotein inhibits gamma interferon-regulated HLA-DR and Fc gamma R1 on human macrophages through Toll-like receptor 2
-
Gehring AJ, Rojas RE, Canaday DH, Lakey DL, Harding CV, et al. (2003) The Mycobacterium tuberculosis 19-kilodalton lipoprotein inhibits gamma interferon-regulated HLA-DR and Fc gamma R1 on human macrophages through Toll-like receptor 2. Infect Immun 71: 4487-4497.
-
(2003)
Infect Immun
, vol.71
, pp. 4487-4497
-
-
Gehring, A.J.1
Rojas, R.E.2
Canaday, D.H.3
Lakey, D.L.4
Harding, C.V.5
-
6
-
-
49649095178
-
Secreted transcription factor controls Mycobacterium tuberculosis virulence
-
Raghavan S, Manzanillo P, Chan K, Dovey C, Cox JS (2008) Secreted transcription factor controls Mycobacterium tuberculosis virulence. Nature 454: 717-721.
-
(2008)
Nature
, vol.454
, pp. 717-721
-
-
Raghavan, S.1
Manzanillo, P.2
Chan, K.3
Dovey, C.4
Cox, J.S.5
-
7
-
-
20444419421
-
Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages
-
Rengarajan J, Bloom BR, Rubin EJ (2005) Genome-wide requirements for Mycobacterium tuberculosis adaptation and survival in macrophages. Proc Natl Acad Sci U S A 102: 8327-8332.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 8327-8332
-
-
Rengarajan, J.1
Bloom, B.R.2
Rubin, E.J.3
-
8
-
-
2942718724
-
Protein kinase G from pathogenic mycobacteria promotes survival within macrophages
-
Walburger A, Koul A, Ferrari G, Nguyen L, Prescianotto-Baschong C, et al. (2004) Protein kinase G from pathogenic mycobacteria promotes survival within macrophages. Science 304: 1800-1804.
-
(2004)
Science
, vol.304
, pp. 1800-1804
-
-
Walburger, A.1
Koul, A.2
Ferrari, G.3
Nguyen, L.4
Prescianotto-Baschong, C.5
-
9
-
-
33847747061
-
Mycobacterium tuberculosis virulence: Lipids inside and out
-
Ehrt S, Schnappinger D (2007) Mycobacterium tuberculosis virulence: lipids inside and out. Nat Med 13: 284-285.
-
(2007)
Nat Med
, vol.13
, pp. 284-285
-
-
Ehrt, S.1
Schnappinger, D.2
-
10
-
-
0142240338
-
Immune control of tuberculosis by IFN-gamma-inducible LRG-47
-
MacMicking JD, Taylor GA, McKinney JD (2003) Immune control of tuberculosis by IFN-gamma-inducible LRG-47. Science 302: 654-659.
-
(2003)
Science
, vol.302
, pp. 654-659
-
-
MacMicking, J.D.1
Taylor, G.A.2
McKinney, J.D.3
-
11
-
-
0041467786
-
Mycobacterium's arrest of phagosome maturation in macrophages requires Rab5 activity and accessibility to iron
-
Kelley VA, Schorey JS (2003) Mycobacterium's arrest of phagosome maturation in macrophages requires Rab5 activity and accessibility to iron. Mol Biol Cell 14: 3366-3377.
-
(2003)
Mol Biol Cell
, vol.14
, pp. 3366-3377
-
-
Kelley, V.A.1
Schorey, J.S.2
-
12
-
-
34447102567
-
Survival of mycobacteria in macrophages is mediated by coronin 1-dependent activation of calcineurin
-
Jayachandran R, Sundaramurthy V, Combaluzier B, Mueller P, Korf H, et al. (2007) Survival of mycobacteria in macrophages is mediated by coronin 1-dependent activation of calcineurin. Cell 130: 37-50.
-
(2007)
Cell
, vol.130
, pp. 37-50
-
-
Jayachandran, R.1
Sundaramurthy, V.2
Combaluzier, B.3
Mueller, P.4
Korf, H.5
-
13
-
-
0030960157
-
Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7
-
Via LE, Deretic D, Ulmer RJ, Hibler NS, Huber LA, et al. (1997) Arrest of mycobacterial phagosome maturation is caused by a block in vesicle fusion between stages controlled by rab5 and rab7. J Biol Chem 272: 13326-13331.
-
(1997)
J Biol Chem
, vol.272
, pp. 13326-13331
-
-
Via, L.E.1
Deretic, D.2
Ulmer, R.J.3
Hibler, N.S.4
Huber, L.A.5
-
14
-
-
0037627408
-
Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest
-
Fratti RA, Chua J, Vergne I, Deretic V (2003) Mycobacterium tuberculosis glycosylated phosphatidylinositol causes phagosome maturation arrest. Proc Natl Acad Sci U S A 100: 5437-5442.
-
(2003)
Proc Natl Acad Sci U S A
, vol.100
, pp. 5437-5442
-
-
Fratti, R.A.1
Chua, J.2
Vergne, I.3
Deretic, V.4
-
15
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi Y, Massague J (2003) Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685-700.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
16
-
-
1242276189
-
D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a
-
Rena G, Bain J, Elliott M, Cohen P (2004) D4476, a cell-permeant inhibitor of CK1, suppresses the site-specific phosphorylation and nuclear exclusion of FOXO1a. EMBO Rep 5: 60-65.
-
(2004)
EMBO Rep
, vol.5
, pp. 60-65
-
-
Rena, G.1
Bain, J.2
Elliott, M.3
Cohen, P.4
-
17
-
-
36549040859
-
The selectivity of protein kinase inhibitors: A further update
-
Bain J, Plater L, Elliott M, Shpiro N, Hastie CJ, et al. (2007) The selectivity of protein kinase inhibitors: a further update. Biochem J 408: 297-315.
-
(2007)
Biochem J
, vol.408
, pp. 297-315
-
-
Bain, J.1
Plater, L.2
Elliott, M.3
Shpiro, N.4
Hastie, C.J.5
-
18
-
-
3142748521
-
Casein kinase Iepsilon plays a functional role in the transforming growth factor-beta signaling pathway
-
Waddell DS, Liberati NT, Guo X, Frederick JP, Wang XF (2004) Casein kinase Iepsilon plays a functional role in the transforming growth factor-beta signaling pathway. J Biol Chem 279: 29236-29246.
-
(2004)
J Biol Chem
, vol.279
, pp. 29236-29246
-
-
Waddell, D.S.1
Liberati, N.T.2
Guo, X.3
Frederick, J.P.4
Wang, X.F.5
-
19
-
-
2942589081
-
Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4Hpyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain
-
Sawyer JS, Beight DW, Britt KS, Anderson BD, Campbell RM, et al. (2004) Synthesis and activity of new aryl- and heteroaryl-substituted 5,6-dihydro-4Hpyrrolo[1,2-b]pyrazole inhibitors of the transforming growth factor-beta type I receptor kinase domain. Bioorg Med Chem Lett 14: 3581-3584.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 3581-3584
-
-
Sawyer, J.S.1
Beight, D.W.2
Britt, K.S.3
Anderson, B.D.4
Campbell, R.M.5
-
20
-
-
33847704942
-
Challenges in tuberculosis drug research and development
-
Ginsberg AM, Spigelman M (2007) Challenges in tuberculosis drug research and development. Nat Med 13: 290-294.
-
(2007)
Nat Med
, vol.13
, pp. 290-294
-
-
Ginsberg, A.M.1
Spigelman, M.2
-
21
-
-
0034680167
-
Molecular mechanisms that confer antibacterial drug resistance
-
Walsh C (2000) Molecular mechanisms that confer antibacterial drug resistance. Nature 406: 775-781.
-
(2000)
Nature
, vol.406
, pp. 775-781
-
-
Walsh, C.1
-
22
-
-
48849094355
-
Host-directed drug targeting of factors hijacked by pathogens
-
Schwegmann A, Brombacher F (2008) Host-directed drug targeting of factors hijacked by pathogens. Sci Signal 1: re8.
-
(2008)
Sci Signal
, vol.1
-
-
Schwegmann, A.1
Brombacher, F.2
-
23
-
-
23844442475
-
Genomewide RNAi screen for host factors required for intracellular bacterial infection
-
Agaisse H, Burrack LS, Philips JA, Rubin EJ, Perrimon N, et al. (2005) Genomewide RNAi screen for host factors required for intracellular bacterial infection. Science 309: 1248-1251.
-
(2005)
Science
, vol.309
, pp. 1248-1251
-
-
Agaisse, H.1
Burrack, L.S.2
Philips, J.A.3
Rubin, E.J.4
Perrimon, N.5
-
24
-
-
39349097864
-
Identification of host proteins required for HIV infection through a functional genomic screen
-
Brass AL, Dykxhoorn DM, Benita Y, Yan N, Engelman A, et al. (2008) Identification of host proteins required for HIV infection through a functional genomic screen. Science 319: 921-926.
-
(2008)
Science
, vol.319
, pp. 921-926
-
-
Brass, A.L.1
Dykxhoorn, D.M.2
Benita, Y.3
Yan, N.4
Engelman, A.5
-
25
-
-
52949130695
-
Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication
-
Konig R, Zhou Y, Elleder D, Diamond TL, Bonamy GM, et al. (2008) Global analysis of host-pathogen interactions that regulate early-stage HIV-1 replication. Cell 135: 49-60.
-
(2008)
Cell
, vol.135
, pp. 49-60
-
-
Konig, R.1
Zhou, Y.2
Elleder, D.3
Diamond, T.L.4
Bonamy, G.M.5
-
26
-
-
51649095289
-
RNA interference screen for human genes associated with West Nile virus infection
-
Krishnan MN, Ng A, Sukumaran B, Gilfoy FD, Uchil PD, et al. (2008) RNA interference screen for human genes associated with West Nile virus infection. Nature 455: 242-245.
-
(2008)
Nature
, vol.455
, pp. 242-245
-
-
Krishnan, M.N.1
Ng, A.2
Sukumaran, B.3
Gilfoy, F.D.4
Uchil, P.D.5
-
27
-
-
23844531867
-
Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection
-
Philips JA, Rubin EJ, Perrimon N (2005) Drosophila RNAi screen reveals CD36 family member required for mycobacterial infection. Science 309: 1251-1253.
-
(2005)
Science
, vol.309
, pp. 1251-1253
-
-
Philips, J.A.1
Rubin, E.J.2
Perrimon, N.3
-
28
-
-
42949162611
-
RNAi screen reveals an Abl kinase-dependent host cell pathway involved in Pseudomonas aeruginosa internalization
-
doi:10.1371/journal.ppat.1000031
-
Pielage JF, Powell KR, Kalman D, Engel JN (2008) RNAi screen reveals an Abl kinase-dependent host cell pathway involved in Pseudomonas aeruginosa internalization. PLoS Pathog 4: e1000031. doi:10.1371/journal.ppat.1000031.
-
(2008)
PLoS Pathog
, vol.4
-
-
Pielage, J.F.1
Powell, K.R.2
Kalman, D.3
Engel, J.N.4
-
29
-
-
57149119672
-
Kinome-wide RNAi screen implicates at least 5 host hepatocyte kinases in Plasmodium sporozoite infection
-
doi:10.1371/journal.ppat.1000201
-
Prudencio M, Rodrigues CD, Hannus M, Martin C, Real E, et al. (2008) Kinome-wide RNAi screen implicates at least 5 host hepatocyte kinases in Plasmodium sporozoite infection. PLoS Pathog 4: e1000201. doi:10.1371/journal.ppat.1000201.
-
(2008)
PLoS Pathog
, vol.4
-
-
Prudencio, M.1
Rodrigues, C.D.2
Hannus, M.3
Martin, C.4
Real, E.5
-
30
-
-
36749030024
-
Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1
-
Kuijl C, Savage ND, Marsman M, Tuin AW, Janssen L, et al. (2007) Intracellular bacterial growth is controlled by a kinase network around PKB/AKT1. Nature 450: 725-730.
-
(2007)
Nature
, vol.450
, pp. 725-730
-
-
Kuijl, C.1
Savage, N.D.2
Marsman, M.3
Tuin, A.W.4
Janssen, L.5
-
31
-
-
45449110225
-
Systems biology of persistent infection: Tuberculosis as a case study
-
Young D, Stark J, Kirschner D (2008) Systems biology of persistent infection: tuberculosis as a case study. Nat Rev Microbiol 6: 520-528.
-
(2008)
Nat Rev Microbiol
, vol.6
, pp. 520-528
-
-
Young, D.1
Stark, J.2
Kirschner, D.3
-
32
-
-
52549123569
-
Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence
-
Gan H, Lee J, Ren F, Chen M, Kornfeld H, et al. (2008) Mycobacterium tuberculosis blocks crosslinking of annexin-1 and apoptotic envelope formation on infected macrophages to maintain virulence. Nat Immunol 9: 1189-1197.
-
(2008)
Nat Immunol
, vol.9
, pp. 1189-1197
-
-
Gan, H.1
Lee, J.2
Ren, F.3
Chen, M.4
Kornfeld, H.5
-
33
-
-
33847736295
-
The survival kit of Mycobacterium tuberculosis
-
Warner DF, Mizrahi V (2007) The survival kit of Mycobacterium tuberculosis. Nat Med 13: 282-284.
-
(2007)
Nat Med
, vol.13
, pp. 282-284
-
-
Warner, D.F.1
Mizrahi, V.2
|