Activation of Human Dendritic Cells Following Infection with Mycobacterium tuberculosis

Journal of Immunology

Volumn 159, Issue 2, 1997, Pages 635-643

  Henderson, Robert A ^a,b   Watkins, Simon C ^a   Flynn, Joanne L ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b GLAXOSMITHKLINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIAL ANTIGEN;

ANTIGEN PRESENTATION; ARTICLE; CELL CULTURE; CELLULAR IMMUNITY; DENDRITIC CELL; HUMAN; IMMUNOLOGY; MICROBIOLOGY; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTOSIS; T LYMPHOCYTE; TUBERCULOSIS;

ANTIGEN PRESENTATION; ANTIGENS, BACTERIAL; CELLS, CULTURED; DENDRITIC CELLS; HUMANS; IMMUNITY, CELLULAR; MYCOBACTERIUM TUBERCULOSIS; PHAGOCYTOSIS; T-LYMPHOCYTES; TUBERCULOSIS;

EID: 0031570821     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. Steinman, R. M. 1991. The dendritic cell system and its role in immunogenicity. Annu. Rev. Immunol. 11:403.
2. Austyn, J. M. 1996. New insights into the mobilization and phagocytic activity of dendritic cells. J. Exp. Med. 183:1287.
3. Roake, J. A., A. S. Rao, P. J. Morris, C. P. Larsen, D. F. Hankins, and J. M. Austyn. 1995. Dendritic cell loss from non-lymphoid tissues alter systemic administration of lipopolysaccharide, tumor necrosis factor, and interleukin 1. J. Exp. Med. 181:2237.
4. Cumberbatch, M., and I. Kimber. 1992. Dermal tumour necrosis factor-alpha induces dendritic cell migration to draining lymph nodes, and possibly provides one stimulus for Langerhans' cell migration. Immunology 75:257.
5. Larsen, C. P., R. M. Steinman, M. Witmer-Pack, D. F. Hankins, P. J. Morris, and J. M. Austyn. 1990. Migration and maturation of Langerhans cells in skin transplants and explants. J. Exp. Med. 172:1483.
6. O'Doherty, U., R. M. Steinman, M. Peng, P. U. Cameron, S. Gezelter, I. Kopeloff, W. J. Swiggard, M. Pope, and N. Bhardwaj. 1993. Dendritic cells isolated from human blood express CD4 and mature into typical immunostimulatory dendritic cells after culture in monocyte-conditioned medium. J. Exp. Med. 178:1067.
7. + T cells. J. Immunol. 154:5701.
8. Heufler, C., F. Koch, U. Stanzl, G. Topar, M. Wysocka, G. Trinchieri, A. Enk, R. M. Steinman, N. Romani, and G. Schuler. 1996. Interleukin-12 is produced by dendritic cells and mediates T helper 1 development as well as interferon-γ production by T helper 1 cells. Eur. J. Immunol. 26:659.
9. Romani, N., S. Gruner, D. Brang, E. Kampgen, A. Lenz, B. Trockenbacker, G. Konwalinka, and P. O. Tritsch. 1994. Proliferating dendritic cell progenitors in human blood. J. Exp. Med. 180:83.
10. Sallusto, F., and A. Lanzavecchia. 1994. Efficient presentation of soluble antigen by cultured human dendritic cells is maintained by granulocyte/macrophage colony-stimulating factor plus IL-4 and downregulaled by tumor necrosis factor-α. J. Exp. Med. 179:1109.
11. Sallusto, F., M. Cella, C. Danieli, and A. Lanzavecchia. 1995. Dendritic cells use macropinocytosis and the mannose receptor to concentrate macromolecules in the major histocompatibility complex class II compartment: downregulation by cytokines and bacterial products. J. Exp. Med. 182:389.
12. Holt, P. G., and M. A. Schon-Hegrad. 1987. Localization of T cells, macrophages, and dendritic cells in rat respiratory tract tissue: implications for immune function studies. Immunology 62:349.
13. Sertl, K., T. Takemura, E. Tschachler, V. J. Ferrans, M. A. Kaliner, and E. M. Shevach. 1986. Dendritic cells with antigen-presenting capability reside in airway epithelium, lung parenchyma, and visceral pleura. J. Exp. Med. 163:436.
14. Havenith, C. E. G., A. J. Breedijk, and E. C. M. Hoefsmit. 1992. Effect of bacillus Calmette-Guerin inoculation on numbers of dendritic cells in bronchoalveolar lavages of rats. Immunobiology 184:336.
15. Esa, A. H., S. J. Noga, A. D. Donnenberg, and A. D. Hess. 1986. Immunological heterogeneity of human monocyte subsets prepared by counterflow centrifugation elutriation. Immunology 59:95.
16. Moll, H., H. Fuchs, C. Blank, and M. Rollinghoff. 1993. Langerhans cells transport Leishmania major from the infected skin to the draining lymph node for presentation to antigen-specific T cells. Eur. J. Immunol. 23:1595.
17. Moll, H., S. Flohe, and M. Rollinghoff. 1995. Dendritic cells in Leishmania major-immune mice harbor persistent parasites and mediate an antigen-specific T cell immune response. Eur. J. Immunol. 25:693.
18. Guzman, C., M. Rohde, M. Bock, and K. N. Timmis. 1994. Invasion and intracellular survival of Bordetella bronchiseptica in mouse dendritic cells. Infect. Immun. 62:5528.
19. Inaba, K., M. Inaba, M. Naito, and R. M. Steinman. 1993. Dendritic cell progenitors phagocytose particulates, including bacillus Calmette-Guerin organisms, and sensitize mice to mycobacterial antigens in vivo. J. Exp. Med. 178:479.
20. Filgueira, L., F. O. Nestle, M. Rittig, H. I. Joller, and P. Groscurth. 1996. Human dendritic cells phagocytose and process Borrelia burgdorferi. J. Immunol. 157:2998.
21. Reise-Sousa, C., P. D. Stahl, and J. M. Austyn. 1993. Phagocytosis of antigens by Langerhans cells in vitro. J. Exp. Med. 178:509.
22. McLellan, A. D., R. V. Sorg, L. Williams, and D. N. J. Hart. 1996. Human dendritic cells activate T lymphocytes via a CD40:CD40 ligand dependent pathway. Eur. J. Immunol. 26:1204.
23. Caux, C., C. Massacrier, B. Vandervliet, B. Dubois, C. Van Kooten, I. Durand, and J. Banchereau. 1994. Activation of human dendritic cells through CD40 cross-linking. J. Exp. Med. 180:1263.
24. Scheicher, C., M. Mehlig, H.-P. Dienes, and K. Reske. 1995. Uptake of microparticle-adsorbed protein antigen by bone marrow-derived dendritic cells results in up-regulation of interleukin-1α and interleukin-12 p40/p.35 and triggers prolonged, efficient antigen presentation. Eur. J. Immunol. 25:1566.
25. Sieling, P. A., D. Chatterjee, S. A. Porcelli, T. I. Prigozy, R. J. Mazzaccaro, T. Soriano, B. R. Bloom, M. B. Brenner, M. Kronenberg, P. J. Brennan, and R. L. Modlin. 1995. CD1-restricted T cell recognition of microbial lipoglycan antigens. Science 269:227.
26. Beckman, E. M., A. Melian, S. M. Behar, P. A. Sieling, D. Chatterjee, S. T. Furlong, R. Matsumoto, J. P. Rosat, R. L. Modlin, and S. A. Porcelli. 1996. CD1c restricts responses of mycobacteria-specific T cells. J. Immunol. 157:2795.
27. Barnes, P. F., R. L. Modlin, and J. J. Ellner. 1994. T-cell responses and cytokines. In Tuberculosis: Pathogenesis, Protection, and Control. B. R. Bloom, ed. American Society for Microbiology, Washington, DC, p. 417.
28. Koch, F., U. Stanzl, P. Jennewein, K. Janke, C. Heufler, E. Kampgen, N. Romani, and G. Schuler. 1996. High level IL-12 production by murine dendritic cells: upregulation via MHC Class II and CD40 molecules and downregulation by IL-4 and IL-10. J. Exp. Med. 184:741.
29. Cella, M., D. Scheidegger, K. Palmer-Lehmann, P. Lane, A. Lanzavecchia, and C. Alber. 1996. Ligation of CD40 on dendritic cells triggers production of high levels of interleukin-12 and enhances T cell stimulatory capacity: T-T help via APC activation. J. Exp. Med. 184:747.
30. McDonough, K. A., Y. Kress, and B. R. Bloom. 1993. Pathogenesis of tuberculosis: interaction of Mycobacterium tuberculosis with macrophages. Infect. Immun. 61:2763.
31. Pancholi, P., R. M. Steinman, and N. Bhardwaj. 1992. Dendritic cells efficiently immunoselect mycobacterial-reactive T cells in human blood, including clonable antigen-reactive precursors. Immunology 76:217.