Mycobacterium tuberculosis protein tyrosine phosphatase (PtpA) excludes host vacuolar-H +-ATPase to inhibit phagosome acidification

Proceedings of the National Academy of Sciences of the United States of America

Volumn 108, Issue 48, 2011, Pages 19371-19376

  Wong, Dennis ^a   Bach, Horacio ^a   Sun, Jim ^a   Hmama, Zakaria ^a   Av Gay, Yossef ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Phagocytosis; Vesicular trafficking

Indexed keywords

CELL PROTEIN; PROTEIN SUBUNIT; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE A; PROTON TRANSPORTING ADENOSINE TRIPHOSPHATASE; UNCLASSIFIED DRUG; VACUOLAR PROTEIN SORTING 33B;

ACIDIFICATION; ALPHA HELIX; AMINO ACID SEQUENCE; ARTICLE; BACTERIAL SURVIVAL; CARBOXY TERMINAL SEQUENCE; CELL FUSION; COMPLEX FORMATION; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VIVO STUDY; LYSOSOME; MACROPHAGE; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PHAGOSOME; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DEPHOSPHORYLATION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; TUBERCULOSIS;

CLONING, MOLECULAR; GENETIC VECTORS; HYDROGEN-ION CONCENTRATION; MICROSCOPY, FLUORESCENCE; MONOCYTES; MYCOBACTERIUM TUBERCULOSIS; PHAGOSOMES; PROTEIN INTERACTION MAPPING; PROTEIN TYROSINE PHOSPHATASES; VACUOLAR PROTON-TRANSLOCATING ATPASES;

EID: 82755181483     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1109201108     Document Type: Article

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