-
1
-
-
77955658245
-
Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo
-
Kuhn AN, Diken M, Kreiter S, Selmi A, Kowalska J, Jemielity J, et al. Phosphorothioate cap analogs increase stability and translational efficiency of RNA vaccines in immature dendritic cells and induce superior immune responses in vivo. Gene Ther 2010; 17(8): 961-71.
-
(2010)
Gene Ther
, vol.17
, Issue.8
, pp. 961-971
-
-
Kuhn, A.N.1
Diken, M.2
Kreiter, S.3
Selmi, A.4
Kowalska, J.5
Jemielity, J.6
-
2
-
-
63949083280
-
What is (still not) known of the mechanism by which electroporation mediates gene transfer and expression in cells and tissues
-
Escoffre JM, Portet T, Wasungu L, Teissie J, Dean D, Rols MP. What is (still not) known of the mechanism by which electroporation mediates gene transfer and expression in cells and tissues. Mol Biotechnol 2009; 41(3): 286-95.
-
(2009)
Mol Biotechnol
, vol.41
, Issue.3
, pp. 286-295
-
-
Escoffre, J.M.1
Portet, T.2
Wasungu, L.3
Teissie, J.4
Dean, D.5
Rols, M.P.6
-
3
-
-
77950857472
-
Progress and prospects: Nuclear import of nonviral vectors
-
Lam AP, Dean DA. Progress and prospects: nuclear import of nonviral vectors. Gene Ther 2010; 17(4): 439-47.
-
(2010)
Gene Ther
, vol.17
, Issue.4
, pp. 439-447
-
-
Lam, A.P.1
Dean, D.A.2
-
4
-
-
0024828050
-
Synthesis of long, capped transcripts in vitro by SP6 and T7 RNA polymerases
-
Yisraeli JK, Melton DA. Synthesis of long, capped transcripts in vitro by SP6 and T7 RNA polymerases. Methods Enzymol 1989; 180: 42-50.
-
(1989)
Methods Enzymol
, vol.180
, pp. 42-50
-
-
Yisraeli, J.K.1
Melton, D.A.2
-
5
-
-
78649845830
-
Synthesis and biological activity of artificial mRNA prepared with novel phosphorylating reagents
-
Nagata S, Hamasaki T, Uetake K, Masuda H, Takagaki K, Oka N, et al. Synthesis and biological activity of artificial mRNA prepared with novel phosphorylating reagents. Nucleic Acids Res 2010; 38(21): 7845-57.
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.21
, pp. 7845-7857
-
-
Nagata, S.1
Hamasaki, T.2
Uetake, K.3
Masuda, H.4
Takagaki, K.5
Oka, N.6
-
6
-
-
33845497677
-
Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells
-
Holtkamp S, Kreiter S, Selmi A, Simon P, Koslowski M, Huber C, et al. Modification of antigen-encoding RNA increases stability, translational efficacy, and T-cell stimulatory capacity of dendritic cells. Blood 2006; 108(13): 4009-17.
-
(2006)
Blood
, vol.108
, Issue.13
, pp. 4009-4017
-
-
Holtkamp, S.1
Kreiter, S.2
Selmi, A.3
Simon, P.4
Koslowski, M.5
Huber, C.6
-
7
-
-
3442896311
-
Messenger RNA-based vaccines
-
Pascolo S. Messenger RNA-based vaccines. Expert Opin Biol Ther 2004; 4(8): 1285-94.
-
(2004)
Expert Opin Biol Ther
, vol.4
, Issue.8
, pp. 1285-1294
-
-
Pascolo, S.1
-
8
-
-
79955054845
-
mRNA as gene therapeutic: How to control protein expression
-
Tavernier G, Andries O, Demeester J, Sanders NN, De Smedt SC, Rejman J. mRNA as gene therapeutic: how to control protein expression. J Control Release 2011; 150(3): 238-47.
-
(2011)
J Control Release
, vol.150
, Issue.3
, pp. 238-247
-
-
Tavernier, G.1
Andries, O.2
Demeester, J.3
Sanders, N.N.4
de Smedt, S.C.5
Rejman, J.6
-
9
-
-
82255194361
-
Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA
-
Kariko K, Muramatsu H, Ludwig J, Weissman D. Generating the optimal mRNA for therapy: HPLC purification eliminates immune activation and improves translation of nucleoside-modified, protein-encoding mRNA. Nucleic Acids Res 2011; 39(21): e142.
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.21
-
-
Kariko, K.1
Muramatsu, H.2
Ludwig, J.3
Weissman, D.4
-
10
-
-
77958536106
-
Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA
-
Warren L, Manos PD, Ahfeldt T, Loh YH, Li H, Lau F, et al. Highly efficient reprogramming to pluripotency and directed differentiation of human cells with synthetic modified mRNA. Cell Stem Cell 2010; 7(5): 618-30.
-
(2010)
Cell Stem Cell
, vol.7
, Issue.5
, pp. 618-630
-
-
Warren, L.1
Manos, P.D.2
Ahfeldt, T.3
Loh, Y.H.4
Li, H.5
Lau, F.6
-
11
-
-
77949793550
-
Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors
-
Yakubov E, Rechavi G, Rozenblatt S, Givol D. Reprogramming of human fibroblasts to pluripotent stem cells using mRNA of four transcription factors. Biochem Biophys Res Commun 2010; 394(1): 189-93.
-
(2010)
Biochem Biophys Res Commun
, vol.394
, Issue.1
, pp. 189-193
-
-
Yakubov, E.1
Rechavi, G.2
Rozenblatt, S.3
Givol, D.4
-
12
-
-
0035412401
-
Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: Superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells
-
Van Tendeloo VF, Ponsaerts P, Lardon F, Nijs G, Lenjou M, Van BC, et al. Highly efficient gene delivery by mRNA electroporation in human hematopoietic cells: superiority to lipofection and passive pulsing of mRNA and to electroporation of plasmid cDNA for tumor antigen loading of dendritic cells. Blood 2001; 98(1): 49-56.
-
(2001)
Blood
, vol.98
, Issue.1
, pp. 49-56
-
-
van Tendeloo, V.F.1
Ponsaerts, P.2
Lardon, F.3
Nijs, G.4
Lenjou, M.5
Van, B.C.6
-
13
-
-
78651254192
-
Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach
-
Plews JR, Li J, Jones M, Moore HD, Mason C, Andrews PW, et al. Activation of pluripotency genes in human fibroblast cells by a novel mRNA based approach. PLoS One 2010; 5(12): e14397.
-
(2010)
PLoS One
, vol.5
, Issue.12
-
-
Plews, J.R.1
Li, J.2
Jones, M.3
Moore, H.D.4
Mason, C.5
Andrews, P.W.6
-
14
-
-
40149090498
-
Cellular restriction of retrovirus particle-mediated mRNA transfer
-
Galla M, Schambach A, Towers GJ, Baum C. Cellular restriction of retrovirus particle-mediated mRNA transfer. J Virol 2008; 82(6): 3069-77.
-
(2008)
J Virol
, vol.82
, Issue.6
, pp. 3069-3077
-
-
Galla, M.1
Schambach, A.2
Towers, G.J.3
Baum, C.4
-
15
-
-
6344243521
-
Retroviral pseudotransduction for targeted cell manipulation
-
Galla M, Will E, Kraunus J, Chen L, Baum C. Retroviral pseudotransduction for targeted cell manipulation. Mol Cell 2004; 16(2): 309-15.
-
(2004)
Mol Cell
, vol.16
, Issue.2
, pp. 309-315
-
-
Galla, M.1
Will, E.2
Kraunus, J.3
Chen, L.4
Baum, C.5
-
16
-
-
79959629606
-
Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery
-
Galla M, Schambach A, Falk CS, Maetzig T, Kuehle J, Lange K, et al. Avoiding cytotoxicity of transposases by dose-controlled mRNA delivery. Nucleic Acids Res 2011; 39(16): 7147-60.
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.16
, pp. 7147-7160
-
-
Galla, M.1
Schambach, A.2
Falk, C.S.3
Maetzig, T.4
Kuehle, J.5
Lange, K.6
-
17
-
-
2942705682
-
Green fluorescent protein: Green cells do not always indicate gene expression
-
Nash KL, Lever AM. Green fluorescent protein: green cells do not always indicate gene expression. Gene Ther 2004; 11(11): 882-3.
-
(2004)
Gene Ther
, vol.11
, Issue.11
, pp. 882-883
-
-
Nash, K.L.1
Lever, A.M.2
-
18
-
-
79953331925
-
DARPins: An efficient targeting domain for lentiviral vectors
-
Munch RC, Muhlebach MD, Schaser T, Kneissl S, Jost C, Pluckthun A, et al. DARPins: an efficient targeting domain for lentiviral vectors. Mol Ther 2011; 19(4): 686-93.
-
(2011)
Mol Ther
, vol.19
, Issue.4
, pp. 686-693
-
-
Munch, R.C.1
Muhlebach, M.D.2
Schaser, T.3
Kneissl, S.4
Jost, C.5
Pluckthun, A.6
-
19
-
-
64749102457
-
Lentiviral vectors with measles virus glycoproteins - dream team for gene transfer?
-
Buchholz CJ, Muhlebach MD, Cichutek K. Lentiviral vectors with measles virus glycoproteins - dream team for gene transfer? Trends Biotechnol 2009; 27(5): 259-65.
-
(2009)
Trends Biotechnol
, vol.27
, Issue.5
, pp. 259-265
-
-
Buchholz, C.J.1
Muhlebach, M.D.2
Cichutek, K.3
-
20
-
-
58149374562
-
Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases
-
Beumer KJ, Trautman JK, Bozas A, Liu JL, Rutter J, Gall JG, et al. Efficient gene targeting in Drosophila by direct embryo injection with zinc-finger nucleases. Proc Natl Acad Sci U S A 2008; 105(50): 19821-6.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, Issue.50
, pp. 19821-19826
-
-
Beumer, K.J.1
Trautman, J.K.2
Bozas, A.3
Liu, J.L.4
Rutter, J.5
Gall, J.G.6
-
21
-
-
77956988605
-
Targeted mutagenesis in the silkworm Bombyx mori using zinc finger nuclease mRNA injection
-
Takasu Y, Kobayashi I, Beumer K, Uchino K, Sezutsu H, Sajwan S, et al. Targeted mutagenesis in the silkworm Bombyx mori using zinc finger nuclease mRNA injection. Insect Biochem Mol Biol 2010; 40(10): 759-65.
-
(2010)
Insect Biochem Mol Biol
, vol.40
, Issue.10
, pp. 759-765
-
-
Takasu, Y.1
Kobayashi, I.2
Beumer, K.3
Uchino, K.4
Sezutsu, H.5
Sajwan, S.6
-
22
-
-
79961196358
-
Knockout rats generated by embryo microinjection of TALENs
-
Tesson L, Usal C, Menoret S, Leung E, Niles BJ, Remy S, et al. Knockout rats generated by embryo microinjection of TALENs. Nat Biotechnol 2011; 29(8): 695-6.
-
(2011)
Nat Biotechnol
, vol.29
, Issue.8
, pp. 695-696
-
-
Tesson, L.1
Usal, C.2
Menoret, S.3
Leung, E.4
Niles, B.J.5
Remy, S.6
-
23
-
-
32944464648
-
Pathogen recognition and innate immunity
-
Akira S, Uematsu S, Takeuchi O. Pathogen recognition and innate immunity. Cell 2006; 124(4): 783-801.
-
(2006)
Cell
, vol.124
, Issue.4
, pp. 783-801
-
-
Akira, S.1
Uematsu, S.2
Takeuchi, O.3
-
24
-
-
34248672889
-
Antiviral signaling through pattern recognition receptors
-
Kawai T, Akira S. Antiviral signaling through pattern recognition receptors. J Biochem 2007; 141(2): 137-45.
-
(2007)
J Biochem
, vol.141
, Issue.2
, pp. 137-145
-
-
Kawai, T.1
Akira, S.2
-
25
-
-
48949094095
-
Structural mechanism of RNA recognition by the RIG-I-like receptors
-
Yoneyama M, Fujita T. Structural mechanism of RNA recognition by the RIG-I-like receptors. Immunity 2008; 29(2): 178-81.
-
(2008)
Immunity
, vol.29
, Issue.2
, pp. 178-181
-
-
Yoneyama, M.1
Fujita, T.2
-
26
-
-
77249132637
-
Recognition of viruses by cytoplasmic sensors
-
Wilkins C, Gale M, Jr. Recognition of viruses by cytoplasmic sensors. Curr Opin Immunol 2010; 22(1): 41-7.
-
(2010)
Curr Opin Immunol
, vol.22
, Issue.1
, pp. 41-47
-
-
Wilkins, C.1
Gale Jr., M.2
-
27
-
-
79551687500
-
Regulation of innate immunity through RNA structure and the protein kinase PKR
-
Nallagatla SR, Toroney R, Bevilacqua PC. Regulation of innate immunity through RNA structure and the protein kinase PKR. Curr Opin Struct Biol 2011; 21(1): 119-27.
-
(2011)
Curr Opin Struct Biol
, vol.21
, Issue.1
, pp. 119-127
-
-
Nallagatla, S.R.1
Toroney, R.2
Bevilacqua, P.C.3
-
28
-
-
78651335915
-
The RNA Modification Database, RNAMDB: 2011 update
-
Database issue
-
Cantara WA, Crain PF, Rozenski J, McCloskey JA, Harris KA, Zhang X, et al. The RNA Modification Database, RNAMDB: 2011 update. Nucleic Acids Res 2011; 39(Database issue): D195-D201.
-
(2011)
Nucleic Acids Res
, vol.39
-
-
Cantara, W.A.1
Crain, P.F.2
Rozenski, J.3
McCloskey, J.A.4
Harris, K.A.5
Zhang, X.6
-
29
-
-
77957242130
-
Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation
-
Anderson BR, Muramatsu H, Nallagatla SR, Bevilacqua PC, Sansing LH, Weissman D, et al. Incorporation of pseudouridine into mRNA enhances translation by diminishing PKR activation. Nucleic Acids Res 2010; 38(17): 5884-92.
-
(2010)
Nucleic Acids Res
, vol.38
, Issue.17
, pp. 5884-5892
-
-
Anderson, B.R.1
Muramatsu, H.2
Nallagatla, S.R.3
Bevilacqua, P.C.4
Sansing, L.H.5
Weissman, D.6
-
30
-
-
82255164455
-
Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L
-
Anderson BR, Muramatsu H, Jha BK, Silverman RH, Weissman D, Kariko K. Nucleoside modifications in RNA limit activation of 2'-5'-oligoadenylate synthetase and increase resistance to cleavage by RNase L. Nucleic Acids Res 2011; 39(21): 9329-38.
-
(2011)
Nucleic Acids Res
, vol.39
, Issue.21
, pp. 9329-9338
-
-
Anderson, B.R.1
Muramatsu, H.2
Jha, B.K.3
Silverman, R.H.4
Weissman, D.5
Kariko, K.6
-
31
-
-
79751497093
-
Expression of therapeutic proteins after delivery of chemically modified mRNA in mice
-
Kormann MS, Hasenpusch G, Aneja MK, Nica G, Flemmer AW, Herber-Jonat S, et al. Expression of therapeutic proteins after delivery of chemically modified mRNA in mice. Nat Biotechnol 2011; 29(2): 154-7.
-
(2011)
Nat Biotechnol
, vol.29
, Issue.2
, pp. 154-157
-
-
Kormann, M.S.1
Hasenpusch, G.2
Aneja, M.K.3
Nica, G.4
Flemmer, A.W.5
Herber-Jonat, S.6
-
32
-
-
33750976374
-
5'-Triphosphate RNA is the ligand for RIG-I
-
Hornung V, Ellegast J, Kim S, Brzozka K, Jung A, Kato H, et al. 5'-Triphosphate RNA is the ligand for RIG-I. Science 2006; 314(5801): 994-7.
-
(2006)
Science
, vol.314
, Issue.5801
, pp. 994-997
-
-
Hornung, V.1
Ellegast, J.2
Kim, S.3
Brzozka, K.4
Jung, A.5
Kato, H.6
-
33
-
-
33750984771
-
RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates
-
Pichlmair A, Schulz O, Tan CP, Naslund TI, Liljestrom P, Weber F, et al. RIG-I-mediated antiviral responses to single-stranded RNA bearing 5'-phosphates. Science 2006; 314(5801): 997-1001.
-
(2006)
Science
, vol.314
, Issue.5801
, pp. 997-1001
-
-
Pichlmair, A.1
Schulz, O.2
Tan, C.P.3
Naslund, T.I.4
Liljestrom, P.5
Weber, F.6
-
34
-
-
77955352428
-
Innate immune suppression enables frequent transfection with RNA encoding reprogramming proteins
-
Angel M, Yanik MF. Innate immune suppression enables frequent transfection with RNA encoding reprogramming proteins. PLoS One 2010; 5(7): e11756.
-
(2010)
PLoS One
, vol.5
, Issue.7
-
-
Angel, M.1
Yanik, M.F.2
-
37
-
-
60149090021
-
The many pathways of RNA degradation
-
Houseley J, Tollervey D. The many pathways of RNA degradation. Cell 2009; 136(4): 763-76.
-
(2009)
Cell
, vol.136
, Issue.4
, pp. 763-776
-
-
Houseley, J.1
Tollervey, D.2
-
38
-
-
85011942140
-
The eukaryotic RNA exosome: Same scaffold but variable catalytic subunits
-
Lykke-Andersen S, Tomecki R, Jensen TH, Dziembowski A. The eukaryotic RNA exosome: same scaffold but variable catalytic subunits. RNA Biol 2011; 8(1): 61-6.
-
(2011)
RNA Biol
, vol.8
, Issue.1
, pp. 61-66
-
-
Lykke-Andersen, S.1
Tomecki, R.2
Jensen, T.H.3
Dziembowski, A.4
-
39
-
-
47749109512
-
Mechanistic and kinetic analysis of the DcpS scavenger decapping enzyme
-
Liu SW, Rajagopal V, Patel SS, Kiledjian M. Mechanistic and kinetic analysis of the DcpS scavenger decapping enzyme. J Biol Chem 2008; 283(24): 16427-36.
-
(2008)
J Biol Chem
, vol.283
, Issue.24
, pp. 16427-16436
-
-
Liu, S.W.1
Rajagopal, V.2
Patel, S.S.3
Kiledjian, M.4
-
40
-
-
78149426485
-
Multiple mRNA decapping enzymes in mammalian cells
-
Song MG, Li Y, Kiledjian M. Multiple mRNA decapping enzymes in mammalian cells. Mol Cell 2010; 40(3): 423-32.
-
(2010)
Mol Cell
, vol.40
, Issue.3
, pp. 423-432
-
-
Song, M.G.1
Li, Y.2
Kiledjian, M.3
-
41
-
-
79951969817
-
Coupled 5' nucleotide recognition and processivity in Xrn1-mediated mRNA decay
-
Jinek M, Coyle SM, Doudna JA. Coupled 5' nucleotide recognition and processivity in Xrn1-mediated mRNA decay. Mol Cell 2011; 41(5): 600-8.
-
(2011)
Mol Cell
, vol.41
, Issue.5
, pp. 600-608
-
-
Jinek, M.1
Coyle, S.M.2
Doudna, J.A.3
-
42
-
-
79952362044
-
Structural and biochemical studies of the 5'-3' exoribonuclease Xrn1
-
Chang JH, Xiang S, Xiang K, Manley JL, Tong L. Structural and biochemical studies of the 5'-3' exoribonuclease Xrn1. Nat Struct Mol Biol 2011; 18(3): 270-6.
-
(2011)
Nat Struct Mol Biol
, vol.18
, Issue.3
, pp. 270-276
-
-
Chang, J.H.1
Xiang, S.2
Xiang, K.3
Manley, J.L.4
Tong, L.5
-
43
-
-
0027214097
-
Yeast cells lacking 5'-3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure
-
Hsu CL, Stevens A. Yeast cells lacking 5'-3' exoribonuclease 1 contain mRNA species that are poly(A) deficient and partially lack the 5' cap structure. Mol Cell Biol 1993; 13(8): 4826-35.
-
(1993)
Mol Cell Biol
, vol.13
, Issue.8
, pp. 4826-4835
-
-
Hsu, C.L.1
Stevens, A.2
-
45
-
-
77956034926
-
Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism
-
Tomecki R, Dziembowski A. Novel endoribonucleases as central players in various pathways of eukaryotic RNA metabolism. RNA 2010; 16(9): 1692-724.
-
(2010)
RNA
, vol.16
, Issue.9
, pp. 1692-1724
-
-
Tomecki, R.1
Dziembowski, A.2
-
46
-
-
75149146546
-
Endoribonucleases--enzymes gaining spotlight in mRNA metabolism
-
Li WM, Barnes T, Lee CH. Endoribonucleases--enzymes gaining spotlight in mRNA metabolism. FEBS J 2010; 277(3): 627-41.
-
(2010)
FEBS J
, vol.277
, Issue.3
, pp. 627-641
-
-
Li, W.M.1
Barnes, T.2
Lee, C.H.3
-
47
-
-
58149216546
-
RNA stability: Is it the endo' the world as we know it?
-
Wilusz J. RNA stability: is it the endo' the world as we know it? Nat Struct Mol Biol 2009; 16(1): 9-10.
-
(2009)
Nat Struct Mol Biol
, vol.16
, Issue.1
, pp. 9-10
-
-
Wilusz, J.1
-
48
-
-
39349103969
-
Vaccination with messenger RNA (mRNA)
-
Pascolo S. Vaccination with messenger RNA (mRNA). Handb Exp Pharmacol 2008; (183): 221-35.
-
(2008)
Handb Exp Pharmacol
, Issue.183
, pp. 221-235
-
-
Pascolo, S.1
-
49
-
-
0029400164
-
Reverse 5' caps in RNAs made in vitro by phage RNA polymerases
-
Pasquinelli AE, Dahlberg JE, Lund E. Reverse 5' caps in RNAs made in vitro by phage RNA polymerases. RNA 1995; 1(9): 957-67.
-
(1995)
RNA
, vol.1
, Issue.9
, pp. 957-967
-
-
Pasquinelli, A.E.1
Dahlberg, J.E.2
Lund, E.3
-
50
-
-
0041331485
-
Novel anti-reverse cap analogs with superior translational properties
-
Jemielity J, Fowler T, Zuberek J, Stepinski J, Lewdorowicz M, Niedzwiecka A, et al. Novel anti-reverse cap analogs with superior translational properties. RNA 2003; 9(9): 1108-22.
-
(2003)
RNA
, vol.9
, Issue.9
, pp. 1108-1122
-
-
Jemielity, J.1
Fowler, T.2
Zuberek, J.3
Stepinski, J.4
Lewdorowicz, M.5
Niedzwiecka, A.6
-
51
-
-
0037165409
-
Synthesis and application of a chain-terminating dinucleotide mRNA cap analog
-
Peng ZH, Sharma V, Singleton SF, Gershon PD. Synthesis and application of a chain-terminating dinucleotide mRNA cap analog. Org Lett 2002; 4(2): 161-4.
-
(2002)
Org Lett
, vol.4
, Issue.2
, pp. 161-164
-
-
Peng, Z.H.1
Sharma, V.2
Singleton, S.F.3
Gershon, P.D.4
-
52
-
-
0034768443
-
Synthesis and properties of mRNAs containing the novel antireverse cap analogs 7-methyl(3'-O-methyl)GpppG and 7-methyl (3'-deoxy)GpppG
-
Stepinski J, Waddell C, Stolarski R, Darzynkiewicz E, Rhoads RE. Synthesis and properties of mRNAs containing the novel antireverse cap analogs 7-methyl(3'-O-methyl)GpppG and 7-methyl (3'-deoxy)GpppG. RNA 2001; 7(10): 1486-95.
-
(2001)
RNA
, vol.7
, Issue.10
, pp. 1486-1495
-
-
Stepinski, J.1
Waddell, C.2
Stolarski, R.3
Darzynkiewicz, E.4
Rhoads, R.E.5
-
53
-
-
30544433619
-
mRNA transfection of dendritic cells: Synergistic effect of ARCA mRNA capping with Poly(A) chains in cis and in trans for a high protein expression level
-
Mockey M, Goncalves C, Dupuy FP, Lemoine FM, Pichon C, Midoux P. mRNA transfection of dendritic cells: synergistic effect of ARCA mRNA capping with Poly(A) chains in cis and in trans for a high protein expression level. Biochem Biophys Res Commun 2006; 340(4): 1062-8.
-
(2006)
Biochem Biophys Res Commun
, vol.340
, Issue.4
, pp. 1062-1068
-
-
Mockey, M.1
Goncalves, C.2
Dupuy, F.P.3
Lemoine, F.M.4
Pichon, C.5
Midoux, P.6
-
54
-
-
33846912739
-
Dendritic cells transfected with interleukin-12 and tumor-associated antigen messenger RNA induce high avidity cytotoxic T cells
-
Bontkes HJ, Kramer D, Ruizendaal JJ, Kueter EW, Van Tendeloo VF, Meijer CJ, et al. Dendritic cells transfected with interleukin-12 and tumor-associated antigen messenger RNA induce high avidity cytotoxic T cells. Gene Ther 2007; 14(4): 366-75.
-
(2007)
Gene Ther
, vol.14
, Issue.4
, pp. 366-375
-
-
Bontkes, H.J.1
Kramer, D.2
Ruizendaal, J.J.3
Kueter, E.W.4
van Tendeloo, V.F.5
Meijer, C.J.6
-
55
-
-
33846136138
-
Synthetic messenger RNA as a tool for gene therapy
-
Rabinovich PM, Komarovskaya ME, Ye ZJ, Imai C, Campana D, Bahceci E, et al. Synthetic messenger RNA as a tool for gene therapy. Hum Gene Ther 2006; 17(10): 1027-35.
-
(2006)
Hum Gene Ther
, vol.17
, Issue.10
, pp. 1027-1035
-
-
Rabinovich, P.M.1
Komarovskaya, M.E.2
Ye, Z.J.3
Imai, C.4
Campana, D.5
Bahceci, E.6
-
56
-
-
34247218172
-
Vaccination with dendritic cells transfected with mRNA-encoded folate-receptor-alpha for relapsed metastatic ovarian cancer
-
Hernando JJ, Park TW, Fischer HP, Zivanovic O, Braun M, Polcher M, et al. Vaccination with dendritic cells transfected with mRNA-encoded folate-receptor-alpha for relapsed metastatic ovarian cancer. Lancet Oncol 2007; 8(5): 451-4.
-
(2007)
Lancet Oncol
, vol.8
, Issue.5
, pp. 451-454
-
-
Hernando, J.J.1
Park, T.W.2
Fischer, H.P.3
Zivanovic, O.4
Braun, M.5
Polcher, M.6
-
57
-
-
34548552532
-
Synthesis and application of 2'-fluoro-substituted cap analogs
-
Kore AR, Shanmugasundaram M, Charles I, Cheng AM, Barta TJ. Synthesis and application of 2'-fluoro-substituted cap analogs. Bioorg Med Chem Lett 2007; 17(19): 5295-9.
-
(2007)
Bioorg Med Chem Lett
, vol.17
, Issue.19
, pp. 5295-5299
-
-
Kore, A.R.1
Shanmugasundaram, M.2
Charles, I.3
Cheng, A.M.4
Barta, T.J.5
-
58
-
-
49849097489
-
Synthesis and application of a new 2',3'-isopropylidene guanosine substituted cap analog
-
Kore AR, Shanmugasundaram M, Vlassov AV. Synthesis and application of a new 2',3'-isopropylidene guanosine substituted cap analog. Bioorg Med Chem Lett 2008; 18(17): 4828-32.
-
(2008)
Bioorg Med Chem Lett
, vol.18
, Issue.17
, pp. 4828-4832
-
-
Kore, A.R.1
Shanmugasundaram, M.2
Vlassov, A.V.3
-
59
-
-
69949134881
-
Locked nucleic acid (LNA)-modified dinucleotide mRNA cap analogue: Synthesis, enzymatic incorporation, and utilization
-
Kore AR, Shanmugasundaram M, Charles I, Vlassov AV, Barta TJ. Locked nucleic acid (LNA)-modified dinucleotide mRNA cap analogue: synthesis, enzymatic incorporation, and utilization. J Am Chem Soc 2009; 131(18): 6364-5.
-
(2009)
J Am Chem Soc
, vol.131
, Issue.18
, pp. 6364-6365
-
-
Kore, A.R.1
Shanmugasundaram, M.2
Charles, I.3
Vlassov, A.V.4
Barta, T.J.5
-
60
-
-
78449258644
-
Synthesis and evaluation of 2'-O-allyl substituted dinucleotide cap analog for mRNA translation
-
Kore AR, Charles I. Synthesis and evaluation of 2'-O-allyl substituted dinucleotide cap analog for mRNA translation. Bioorg Med Chem 2010; 18(22): 8061-5.
-
(2010)
Bioorg Med Chem
, vol.18
, Issue.22
, pp. 8061-8065
-
-
Kore, A.R.1
Charles, I.2
-
61
-
-
4344688972
-
Novel cap analogs for in vitro synthesis of mRNAs with high translational efficiency
-
Grudzien E, Stepinski J, Jankowska-Anyszka M, Stolarski R, Darzynkiewicz E, Rhoads RE. Novel cap analogs for in vitro synthesis of mRNAs with high translational efficiency. RNA 2004; 10(9): 1479-87.
-
(2004)
RNA
, vol.10
, Issue.9
, pp. 1479-1487
-
-
Grudzien, E.1
Stepinski, J.2
Jankowska-Anyszka, M.3
Stolarski, R.4
Darzynkiewicz, E.5
Rhoads, R.E.6
-
62
-
-
33644984354
-
Enzymatically stable 5' mRNA cap analogs: Synthesis and binding studies with human DcpS decapping enzyme
-
Kalek M, Jemielity J, Darzynkiewicz ZM, Bojarska E, Stepinski J, Stolarski R, et al. Enzymatically stable 5' mRNA cap analogs: synthesis and binding studies with human DcpS decapping enzyme. Bioorg Med Chem 2006; 14(9): 3223-30.
-
(2006)
Bioorg Med Chem
, vol.14
, Issue.9
, pp. 3223-3230
-
-
Kalek, M.1
Jemielity, J.2
Darzynkiewicz, Z.M.3
Bojarska, E.4
Stepinski, J.5
Stolarski, R.6
-
63
-
-
33644851380
-
Differential inhibition of mRNA degradation pathways by novel cap analogs
-
Grudzien E, Kalek M, Jemielity J, Darzynkiewicz E, Rhoads RE. Differential inhibition of mRNA degradation pathways by novel cap analogs. J Biol Chem 2006; 281(4): 1857-67.
-
(2006)
J Biol Chem
, vol.281
, Issue.4
, pp. 1857-1867
-
-
Grudzien, E.1
Kalek, M.2
Jemielity, J.3
Darzynkiewicz, E.4
Rhoads, R.E.5
-
64
-
-
79955037730
-
Translation, stability, and resistance to decapping of mRNAs containing caps substituted in the triphosphate chain with BH3, Se, and NH
-
Su W, Slepenkov S, Grudzien-Nogalska E, Kowalska J, Kulis M, Zuberek J, et al. Translation, stability, and resistance to decapping of mRNAs containing caps substituted in the triphosphate chain with BH3, Se, and NH. RNA 2011; 17(5): 978-88.
-
(2011)
RNA
, vol.17
, Issue.5
, pp. 978-988
-
-
Su, W.1
Slepenkov, S.2
Grudzien-Nogalska, E.3
Kowalska, J.4
Kulis, M.5
Zuberek, J.6
-
65
-
-
84857359449
-
Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety--fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis
-
Rydzik AM, Kulis M, Lukaszewicz M, Kowalska J, Zuberek J, Darzynkiewicz ZM, et al. Synthesis and properties of mRNA cap analogs containing imidodiphosphate moiety--fairly mimicking natural cap structure, yet resistant to enzymatic hydrolysis. Bioorg Med Chem 2012; 20(5): 1699-710.
-
(2012)
Bioorg Med Chem
, vol.20
, Issue.5
, pp. 1699-1710
-
-
Rydzik, A.M.1
Kulis, M.2
Lukaszewicz, M.3
Kowalska, J.4
Zuberek, J.5
Darzynkiewicz, Z.M.6
-
66
-
-
44149090552
-
Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS
-
Kowalska J, Lewdorowicz M, Zuberek J, Grudzien-Nogalska E, Bojarska E, Stepinski J, et al. Synthesis and characterization of mRNA cap analogs containing phosphorothioate substitutions that bind tightly to eIF4E and are resistant to the decapping pyrophosphatase DcpS. RNA 2008; 14(6): 1119-31.
-
(2008)
RNA
, vol.14
, Issue.6
, pp. 1119-1131
-
-
Kowalska, J.1
Lewdorowicz, M.2
Zuberek, J.3
Grudzien-Nogalska, E.4
Bojarska, E.5
Stepinski, J.6
-
67
-
-
34748856370
-
Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells
-
Grudzien-Nogalska E, Jemielity J, Kowalska J, Darzynkiewicz E, Rhoads RE. Phosphorothioate cap analogs stabilize mRNA and increase translational efficiency in mammalian cells. RNA 2007; 13(10): 1745-55.
-
(2007)
RNA
, vol.13
, Issue.10
, pp. 1745-1755
-
-
Grudzien-Nogalska, E.1
Jemielity, J.2
Kowalska, J.3
Darzynkiewicz, E.4
Rhoads, R.E.5
-
68
-
-
0037121926
-
Human Dcp2: A catalytically active mRNA decapping enzyme located in specific cytoplasmic structures
-
Van DE, Cougot N, Meyer S, Babajko S, Wahle E, Seraphin B. Human Dcp2: a catalytically active mRNA decapping enzyme located in specific cytoplasmic structures. EMBO J 2002; 21(24): 6915-24.
-
(2002)
EMBO J
, vol.21
, Issue.24
, pp. 6915-6924
-
-
Van, D.E.1
Cougot, N.2
Meyer, S.3
Babajko, S.4
Wahle, E.5
Seraphin, B.6
-
69
-
-
70350521453
-
Phosphoroselenoate dinucleotides for modification of mRNA 5' end
-
Kowalska J, Lukaszewicz M, Zuberek J, Darzynkiewicz E, Jemielity J. Phosphoroselenoate dinucleotides for modification of mRNA 5' end. Chembiochem 2009; 10(15): 2469-73.
-
(2009)
Chembiochem
, vol.10
, Issue.15
, pp. 2469-2473
-
-
Kowalska, J.1
Lukaszewicz, M.2
Zuberek, J.3
Darzynkiewicz, E.4
Jemielity, J.5
-
70
-
-
0041331485
-
Novel anti-reverse cap analogs with superior translational properties
-
Jemielity J, Fowler T, Zuberek J, Stepinski J, Lewdorowicz M, Niedzwiecka A, et al. Novel anti-reverse cap analogs with superior translational properties. RNA 2003; 9(9): 1108-22.
-
(2003)
RNA
, vol.9
, Issue.9
, pp. 1108-1122
-
-
Jemielity, J.1
Fowler, T.2
Zuberek, J.3
Stepinski, J.4
Lewdorowicz, M.5
Niedzwiecka, A.6
-
71
-
-
70349189317
-
Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression
-
Zdanowicz A, Thermann R, Kowalska J, Jemielity J, Duncan K, Preiss T, et al. Drosophila miR2 primarily targets the m7GpppN cap structure for translational repression. Mol Cell 2009; 35(6): 881-8.
-
(2009)
Mol Cell
, vol.35
, Issue.6
, pp. 881-888
-
-
Zdanowicz, A.1
Thermann, R.2
Kowalska, J.3
Jemielity, J.4
Duncan, K.5
Preiss, T.6
-
72
-
-
70350650542
-
Synthetic dinucleotide mRNA cap analogs with tetraphosphate 5',5' bridge containing methylenebis(phosphonate) modification
-
Rydzik AM, Lukaszewicz M, Zuberek J, Kowalska J, Darzynkiewicz ZM, Darzynkiewicz E, et al. Synthetic dinucleotide mRNA cap analogs with tetraphosphate 5',5' bridge containing methylenebis(phosphonate) modification. Org Biomol Chem 2009; 7(22): 4763-76.
-
(2009)
Org Biomol Chem
, vol.7
, Issue.22
, pp. 4763-4776
-
-
Rydzik, A.M.1
Lukaszewicz, M.2
Zuberek, J.3
Kowalska, J.4
Darzynkiewicz, Z.M.5
Darzynkiewicz, E.6
-
73
-
-
77952557529
-
Towards mRNA with superior translational activity: Synthesis and properties of ARCA tetraphosphates with single phosphorothioate modifications
-
Strenkowska M, Kowalska J, Lukaszewicz M, Zuberek J, Su W, Rhoads RE, et al. Towards mRNA with superior translational activity: synthesis and properties of ARCA tetraphosphates with single phosphorothioate modifications. New J Chem 2010; 34(5): 993-1007.
-
(2010)
New J Chem
, vol.34
, Issue.5
, pp. 993-1007
-
-
Strenkowska, M.1
Kowalska, J.2
Lukaszewicz, M.3
Zuberek, J.4
Su, W.5
Rhoads, R.E.6
-
74
-
-
55249105461
-
Ectopic expression of a truncated CD40L protein from synthetic post-transcriptionally capped RNA in dendritic cells induces high levels of IL-12 secretion
-
Tcherepanova IY, Adams MD, Feng X, Hinohara A, Horvatinovich J, Calderhead D, et al. Ectopic expression of a truncated CD40L protein from synthetic post-transcriptionally capped RNA in dendritic cells induces high levels of IL-12 secretion. BMC Mol Biol 2008; 9: 90.
-
(2008)
BMC Mol Biol
, vol.9
, pp. 90
-
-
Tcherepanova, I.Y.1
Adams, M.D.2
Feng, X.3
Hinohara, A.4
Horvatinovich, J.5
Calderhead, D.6
-
75
-
-
42449114149
-
New insights into internal ribosome entry site elements relevant for viral gene expression
-
Martinez-Salas E, Pacheco A, Serrano P, Fernandez N. New insights into internal ribosome entry site elements relevant for viral gene expression. J Gen Virol 2008; 89(Pt 3): 611-26.
-
(2008)
J Gen Virol
, vol.89
, Issue.Pt 3
, pp. 611-626
-
-
Martinez-Salas, E.1
Pacheco, A.2
Serrano, P.3
Fernandez, N.4
-
76
-
-
39649100209
-
Enhanced protein expression by internal ribosomal entry site-driven mRNA translation as a novel approach for in vitro loading of dendritic cells with antigens
-
Tan X, Wan Y. Enhanced protein expression by internal ribosomal entry site-driven mRNA translation as a novel approach for in vitro loading of dendritic cells with antigens. Hum Immunol 2008; 69(1): 32-40.
-
(2008)
Hum Immunol
, vol.69
, Issue.1
, pp. 32-40
-
-
Tan, X.1
Wan, Y.2
-
77
-
-
0141446194
-
Identification of mRNAs associated with alphaCP2-containing RNP complexes
-
Waggoner SA, Liebhaber SA. Identification of mRNAs associated with alphaCP2-containing RNP complexes. Mol Cell Biol 2003; 23(19): 7055-67.
-
(2003)
Mol Cell Biol
, vol.23
, Issue.19
, pp. 7055-7067
-
-
Waggoner, S.A.1
Liebhaber, S.A.2
-
78
-
-
0034898553
-
Structural and functional analysis of an mRNP complex that mediates the high stability of human beta-globin mRNA
-
Yu J, Russell JE. Structural and functional analysis of an mRNP complex that mediates the high stability of human beta-globin mRNA. Mol Cell Biol 2001; 21(17): 5879-88.
-
(2001)
Mol Cell Biol
, vol.21
, Issue.17
, pp. 5879-5888
-
-
Yu, J.1
Russell, J.E.2
-
79
-
-
0030987239
-
Four highly stable eukaryotic mRNAs assemble 3' untranslated region RNA-protein complexes sharing cis and trans components
-
Holcik M, Liebhaber SA. Four highly stable eukaryotic mRNAs assemble 3' untranslated region RNA-protein complexes sharing cis and trans components. Proc Natl Acad Sci U S A 1997; 94(6): 2410-4.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, Issue.6
, pp. 2410-2414
-
-
Holcik, M.1
Liebhaber, S.A.2
-
80
-
-
33644750707
-
A nucleolin-binding 3' untranslated region element stabilizes beta-globin mRNA in vivo
-
Jiang Y, Xu XS, Russell JE. A nucleolin-binding 3' untranslated region element stabilizes beta-globin mRNA in vivo. Mol Cell Biol 2006; 26(6): 2419-29.
-
(2006)
Mol Cell Biol
, vol.26
, Issue.6
, pp. 2419-2429
-
-
Jiang, Y.1
Xu, X.S.2
Russell, J.E.3
-
81
-
-
0141592713
-
Efficient presentation of known HLA class IIrestricted MAGE-A3 epitopes by dendritic cells electroporated with messenger RNA encoding an invariant chain with genetic exchange of class II-associated invariant chain peptide
-
Bonehill A, Heirman C, Tuyaerts S, Michiels A, Zhang Y, van der Bruggen P, et al. Efficient presentation of known HLA class IIrestricted MAGE-A3 epitopes by dendritic cells electroporated with messenger RNA encoding an invariant chain with genetic exchange of class II-associated invariant chain peptide. Cancer Res 2003; 63(17): 5587-94.
-
(2003)
Cancer Res
, vol.63
, Issue.17
, pp. 5587-5594
-
-
Bonehill, A.1
Heirman, C.2
Tuyaerts, S.3
Michiels, A.4
Zhang, Y.5
van der Bruggen, P.6
-
83
-
-
34548472407
-
Lsm proteins bind and stabilize RNAs containing 5' poly(A) tracts
-
Bergman N, Moraes KC, Anderson JR, Zaric B, Kambach C, Schneider RJ, et al. Lsm proteins bind and stabilize RNAs containing 5' poly(A) tracts. Nat Struct Mol Biol 2007; 14(9): 824-31.
-
(2007)
Nat Struct Mol Biol
, vol.14
, Issue.9
, pp. 824-831
-
-
Bergman, N.1
Moraes, K.C.2
Anderson, J.R.3
Zaric, B.4
Kambach, C.5
Schneider, R.J.6
-
84
-
-
0030068269
-
Translation of Sindbis virus mRNA: Analysis of sequences downstream of the initiating AUG codon that enhance translation
-
Frolov I, Schlesinger S. Translation of Sindbis virus mRNA: analysis of sequences downstream of the initiating AUG codon that enhance translation. J Virol 1996; 70(2): 1182-90.
-
(1996)
J Virol
, vol.70
, Issue.2
, pp. 1182-1190
-
-
Frolov, I.1
Schlesinger, S.2
-
85
-
-
0028152741
-
A significantly improved Semliki Forest virus expression system based on translation enhancer segments from the viral capsid gene
-
Sjoberg EM, Suomalainen M, Garoff H. A significantly improved Semliki Forest virus expression system based on translation enhancer segments from the viral capsid gene. Biotechnology (NY) 1994; 12(11): 1127-31.
-
(1994)
Biotechnology (NY)
, vol.12
, Issue.11
, pp. 1127-1131
-
-
Sjoberg, E.M.1
Suomalainen, M.2
Garoff, H.3
-
86
-
-
0027332585
-
5' sequences of rubella virus RNA stimulate translation of chimeric RNAs and specifically interact with two host-encoded proteins
-
Pogue GP, Cao XQ, Singh NK, Nakhasi HL. 5' sequences of rubella virus RNA stimulate translation of chimeric RNAs and specifically interact with two host-encoded proteins. J Virol 1993; 67(12): 7106-17.
-
(1993)
J Virol
, vol.67
, Issue.12
, pp. 7106-7117
-
-
Pogue, G.P.1
Cao, X.Q.2
Singh, N.K.3
Nakhasi, H.L.4
-
87
-
-
37849019535
-
The 3' untranslated region of sindbis virus represses deadenylation of viral transcripts in mosquito and Mammalian cells
-
Garneau NL, Sokoloski KJ, Opyrchal M, Neff CP, Wilusz CJ, Wilusz J. The 3' untranslated region of sindbis virus represses deadenylation of viral transcripts in mosquito and Mammalian cells. J Virol 2008; 82(2): 880-92.
-
(2008)
J Virol
, vol.82
, Issue.2
, pp. 880-892
-
-
Garneau, N.L.1
Sokoloski, K.J.2
Opyrchal, M.3
Neff, C.P.4
Wilusz, C.J.5
Wilusz, J.6
-
88
-
-
77953768679
-
A method for stabilizing RNA for transfection that allows control of expression duration
-
Hayashi T, Lamba DA, Slowik A, Reh TA, Bermingham-McDonogh O. A method for stabilizing RNA for transfection that allows control of expression duration. Dev Dyn 2010; 239(7): 2034-40.
-
(2010)
Dev Dyn
, vol.239
, Issue.7
, pp. 2034-2040
-
-
Hayashi, T.1
Lamba, D.A.2
Slowik, A.3
Reh, T.A.4
Bermingham-McDonogh, O.5
-
89
-
-
20744431725
-
Control of translation by the 5'-and 3'-terminal regions of the dengue virus genome
-
Chiu WW, Kinney RM, Dreher TW. Control of translation by the 5'-and 3'-terminal regions of the dengue virus genome. J Virol 2005; 79(13): 8303-15.
-
(2005)
J Virol
, vol.79
, Issue.13
, pp. 8303-8315
-
-
Chiu, W.W.1
Kinney, R.M.2
Dreher, T.W.3
-
90
-
-
5144228164
-
Enhancement of dengue virus translation: Role of the 3' untranslated region and the terminal 3' stem-loop domain
-
Holden KL, Harris E. Enhancement of dengue virus translation: role of the 3' untranslated region and the terminal 3' stem-loop domain. Virology 2004; 329(1): 119-33.
-
(2004)
Virology
, vol.329
, Issue.1
, pp. 119-133
-
-
Holden, K.L.1
Harris, E.2
-
91
-
-
0027518202
-
Translational control by influenza virus. Selective translation is mediated by sequences within the viral mRNA 5'-untranslated region
-
Garfinkel MS, Katze MG. Translational control by influenza virus. Selective translation is mediated by sequences within the viral mRNA 5'-untranslated region. J Biol Chem 1993; 268(30): 22223-6.
-
(1993)
J Biol Chem
, vol.268
, Issue.30
, pp. 22223-22226
-
-
Garfinkel, M.S.1
Katze, M.G.2
-
92
-
-
8944255627
-
The translation-enhancing region of the Semliki Forest virus subgenome is only functional in the virusinfected cell
-
Sjoberg EM, Garoff H. The translation-enhancing region of the Semliki Forest virus subgenome is only functional in the virusinfected cell. J Gen Virol 1996; 77 (Pt 6): 1323-7.
-
(1996)
J Gen Virol
, vol.77
, Issue.Pt 6
, pp. 1323-1327
-
-
Sjoberg, E.M.1
Garoff, H.2
-
93
-
-
0037413975
-
Modulating gene expression using DNA vaccines with different 3'-UTRs influences antibody titer, seroconversion and cytokine profiles
-
Zinckgraf JW, Silbart LK. Modulating gene expression using DNA vaccines with different 3'-UTRs influences antibody titer, seroconversion and cytokine profiles. Vaccine 2003; 21(15): 1640-9.
-
(2003)
Vaccine
, vol.21
, Issue.15
, pp. 1640-1649
-
-
Zinckgraf, J.W.1
Silbart, L.K.2
-
94
-
-
0018879196
-
Codon catalog usage and the genome hypothesis
-
Grantham R, Gautier C, Gouy M, Mercier R, Pave A. Codon catalog usage and the genome hypothesis. Nucleic Acids Res 1980; 8(1): r49-r62.
-
(1980)
Nucleic Acids Res
, vol.8
, Issue.1
-
-
Grantham, R.1
Gautier, C.2
Gouy, M.3
Mercier, R.4
Pave, A.5
-
95
-
-
0021958933
-
Codon usage and tRNA content in unicellular and multicellular organisms
-
Ikemura T. Codon usage and tRNA content in unicellular and multicellular organisms. Mol Biol Evol 1985; 2(1): 13-34.
-
(1985)
Mol Biol Evol
, vol.2
, Issue.1
, pp. 13-34
-
-
Ikemura, T.1
-
96
-
-
0019308408
-
The influence of codon context on genetic code translation
-
Bossi L, Ruth JR. The influence of codon context on genetic code translation. Nature 1980; 286(5769): 123-7.
-
(1980)
Nature
, vol.286
, Issue.5769
, pp. 123-127
-
-
Bossi, L.1
Ruth, J.R.2
-
97
-
-
84859185749
-
Engineering genes for predictable protein expression
-
Gustafsson C, Minshull J, Govindarajan S, Ness J, Villalobos A, Welch M. Engineering genes for predictable protein expression. Protein Expr Purif 2012; 83(1): 37-46.
-
(2012)
Protein Expr Purif
, vol.83
, Issue.1
, pp. 37-46
-
-
Gustafsson, C.1
Minshull, J.2
Govindarajan, S.3
Ness, J.4
Villalobos, A.5
Welch, M.6
-
98
-
-
80055031054
-
Species-specific codon context rules unveil nonneutrality effects of synonymous mutations
-
Moura GR, Pinheiro M, Freitas A, Oliveira JL, Frommlet JC, Carreto L, et al. Species-specific codon context rules unveil nonneutrality effects of synonymous mutations. PLoS One 2011; 6(10): e26817.
-
(2011)
PLoS One
, vol.6
, Issue.10
-
-
Moura, G.R.1
Pinheiro, M.2
Freitas, A.3
Oliveira, J.L.4
Frommlet, J.C.5
Carreto, L.6
-
99
-
-
56749163584
-
Preferred and avoided codon pairs in three domains of life
-
Tats A, Tenson T, Remm M. Preferred and avoided codon pairs in three domains of life. BMC Genomics 2008; 9: 463.
-
(2008)
BMC Genomics
, vol.9
, pp. 463
-
-
Tats, A.1
Tenson, T.2
Remm, M.3
-
100
-
-
0346104825
-
Mammalian mutation pressure, synonymous codon choice, and mRNA degradation
-
Duan J, Antezana MA. Mammalian mutation pressure, synonymous codon choice, and mRNA degradation. J Mol Evol 2003; 57(6): 694-701.
-
(2003)
J Mol Evol
, vol.57
, Issue.6
, pp. 694-701
-
-
Duan, J.1
Antezana, M.A.2
-
101
-
-
12144251356
-
The AU-rich transcriptome: More than interferons and cytokines, and its role in disease
-
Khabar KS. The AU-rich transcriptome: more than interferons and cytokines, and its role in disease. J Interferon Cytokine Res 2005; 25(1): 1-10.
-
(2005)
J Interferon Cytokine Res
, vol.25
, Issue.1
, pp. 1-10
-
-
Khabar, K.S.1
-
102
-
-
79952289327
-
Multiparameter RNA and codon optimization: A standardized tool to assess and enhance autologous mammalian gene expression
-
Fath S, Bauer AP, Liss M, Spriestersbach A, Maertens B, Hahn P, et al. Multiparameter RNA and codon optimization: a standardized tool to assess and enhance autologous mammalian gene expression. PLoS One 2011; 6(3): e17596.
-
(2011)
PLoS One
, vol.6
, Issue.3
-
-
Fath, S.1
Bauer, A.P.2
Liss, M.3
Spriestersbach, A.4
Maertens, B.5
Hahn, P.6
-
103
-
-
33748686759
-
Simultaneous activation of viral antigen-specific memory CD4+ and CD8+ T-cells using mRNA-electroporated CD40-activated autologous B-cells
-
Van den Bosch GA, Van GE, Ponsaerts P, Nijs G, Lenjou M, Apers L, et al. Simultaneous activation of viral antigen-specific memory CD4+ and CD8+ T-cells using mRNA-electroporated CD40-activated autologous B-cells. J Immunother 2006; 29(5): 512-23.
-
(2006)
J Immunother
, vol.29
, Issue.5
, pp. 512-523
-
-
van den Bosch, G.A.1
Van, G.E.2
Ponsaerts, P.3
Nijs, G.4
Lenjou, M.5
Apers, L.6
-
104
-
-
33344461737
-
Efficient stimulation of HIV-1-specific T cells using dendritic cells electroporated with mRNA encoding autologous HIV-1 Gag and Env proteins
-
Van Gulck ER, Ponsaerts P, Heyndrickx L, Vereecken K, Moerman F, De RA, et al. Efficient stimulation of HIV-1-specific T cells using dendritic cells electroporated with mRNA encoding autologous HIV-1 Gag and Env proteins. Blood 2006; 107(5): 1818-27.
-
(2006)
Blood
, vol.107
, Issue.5
, pp. 1818-1827
-
-
van Gulck, E.R.1
Ponsaerts, P.2
Heyndrickx, L.3
Vereecken, K.4
Moerman, F.5
De, R.A.6
-
105
-
-
58149308061
-
Modified tumour antigen-encoding mRNA facilitates the analysis of naturally occurring and vaccine-induced CD4 and CD8 T cells in cancer patients
-
Knights AJ, Nuber N, Thomson CW, de la Rosa O, Jager E, Tiercy JM, et al. Modified tumour antigen-encoding mRNA facilitates the analysis of naturally occurring and vaccine-induced CD4 and CD8 T cells in cancer patients. Cancer Immunol Immunother 2009; 58(3): 325-38.
-
(2009)
Cancer Immunol Immunother
, vol.58
, Issue.3
, pp. 325-338
-
-
Knights, A.J.1
Nuber, N.2
Thomson, C.W.3
de la Rosa, O.4
Jager, E.5
Tiercy, J.M.6
-
106
-
-
33645997354
-
Codon modification of T cell receptors allows enhanced functional expression in transgenic human T cells
-
Scholten KB, Kramer D, Kueter EW, Graf M, Schoedl T, Meijer CJ, et al. Codon modification of T cell receptors allows enhanced functional expression in transgenic human T cells. Clin Immunol 2006; 119(2): 135-45.
-
(2006)
Clin Immunol
, vol.119
, Issue.2
, pp. 135-145
-
-
Scholten, K.B.1
Kramer, D.2
Kueter, E.W.3
Graf, M.4
Schoedl, T.5
Meijer, C.J.6
-
107
-
-
0024591905
-
The poly(A)-poly(A)-binding protein complex is a major determinant of mRNA stability in vitro
-
Bernstein P, Peltz SW, Ross J. The poly(A)-poly(A)-binding protein complex is a major determinant of mRNA stability in vitro. Mol Cell Biol 1989; 9(2): 659-70.
-
(1989)
Mol Cell Biol
, vol.9
, Issue.2
, pp. 659-670
-
-
Bernstein, P.1
Peltz, S.W.2
Ross, J.3
-
108
-
-
0023405161
-
A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability
-
Sachs AB, Davis RW, Kornberg RD. A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability. Mol Cell Biol 1987; 7(9): 3268-76.
-
(1987)
Mol Cell Biol
, vol.7
, Issue.9
, pp. 3268-3276
-
-
Sachs, A.B.1
Davis, R.W.2
Kornberg, R.D.3
-
109
-
-
0019004777
-
Repeating structure of cytoplasmic poly(A)-ribonucleoprotein
-
Baer BW, Kornberg RD. Repeating structure of cytoplasmic poly(A)-ribonucleoprotein. Proc Natl Acad Sci U S A 1980; 77(4): 1890-2.
-
(1980)
Proc Natl Acad Sci U S A
, vol.77
, Issue.4
, pp. 1890-1892
-
-
Baer, B.W.1
Kornberg, R.D.2
-
110
-
-
0032112017
-
Circularization of mRNA by eukaryotic translation initiation factors
-
Wells SE, Hillner PE, Vale RD, Sachs AB. Circularization of mRNA by eukaryotic translation initiation factors. Mol Cell 1998; 2(1): 135-40.
-
(1998)
Mol Cell
, vol.2
, Issue.1
, pp. 135-140
-
-
Wells, S.E.1
Hillner, P.E.2
Vale, R.D.3
Sachs, A.B.4
-
111
-
-
0031915525
-
Tailing and 3'-end labeling of RNA with yeast poly(A) polymerase and various nucleotides
-
Martin G, Keller W. Tailing and 3'-end labeling of RNA with yeast poly(A) polymerase and various nucleotides. RNA 1998; 4(2): 226-30.
-
(1998)
RNA
, vol.4
, Issue.2
, pp. 226-230
-
-
Martin, G.1
Keller, W.2
-
112
-
-
0039535081
-
Poly(A) tail shortening by a mammalian poly(A)-specific 3'-exoribonuclease
-
Korner CG, Wahle E. Poly(A) tail shortening by a mammalian poly(A)-specific 3'-exoribonuclease. J Biol Chem 1997; 272(16): 10448-56.
-
(1997)
J Biol Chem
, vol.272
, Issue.16
, pp. 10448-10456
-
-
Korner, C.G.1
Wahle, E.2
-
113
-
-
35148891213
-
A placenta-specific gene ectopically activated in many human cancers is essentially involved in malignant cell processes
-
Koslowski M, Sahin U, Mitnacht-Kraus R, Seitz G, Huber C, Tureci O. A placenta-specific gene ectopically activated in many human cancers is essentially involved in malignant cell processes. Cancer Res 2007; 67(19): 9528-34.
-
(2007)
Cancer Res
, vol.67
, Issue.19
, pp. 9528-9534
-
-
Koslowski, M.1
Sahin, U.2
Mitnacht-Kraus, R.3
Seitz, G.4
Huber, C.5
Tureci, O.6
-
114
-
-
0026322151
-
A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma
-
van der Bruggen P, Traversari C, Chomez P, Lurquin C, De PE, van den Eynde B, et al. A gene encoding an antigen recognized by cytolytic T lymphocytes on a human melanoma. Science 1991; 254(5038): 1643-7.
-
(1991)
Science
, vol.254
, Issue.5038
, pp. 1643-1647
-
-
van der Bruggen, P.1
Traversari, C.2
Chomez, P.3
Lurquin, C.4
De, P.E.5
van den Eynde, B.6
-
115
-
-
77954552963
-
TAA polyepitope DNA-based vaccines: A potential tool for cancer therapy
-
Bei R, Scardino A. TAA polyepitope DNA-based vaccines: a potential tool for cancer therapy. J Biomed Biotechnol 2010; 2010: 102758.
-
(2758)
J Biomed Biotechnol
, vol.2010
, Issue.10
, pp. 2010
-
-
Bei, R.1
Scardino, A.2
-
117
-
-
84860303882
-
Viral and non-viral methods to genetically modify dendritic cells
-
Humbert JM, Halary F. Viral and non-viral methods to genetically modify dendritic cells. Curr Gene Ther 2012; 12(2): 127-36.
-
(2012)
Curr Gene Ther
, vol.12
, Issue.2
, pp. 127-136
-
-
Humbert, J.M.1
Halary, F.2
-
118
-
-
84858780815
-
Cancer immunotherapy via dendritic cells
-
Palucka K, Banchereau J. Cancer immunotherapy via dendritic cells. Nat Rev Cancer 2012; 12(4): 265-77.
-
(2012)
Nat Rev Cancer
, vol.12
, Issue.4
, pp. 265-277
-
-
Palucka, K.1
Banchereau, J.2
-
119
-
-
37349109250
-
Plasmid DNA-and messenger RNA-based anti-cancer vaccination
-
Weide B, Garbe C, Rammensee HG, Pascolo S. Plasmid DNA-and messenger RNA-based anti-cancer vaccination. Immunol Lett 2008; 115(1): 33-42.
-
(2008)
Immunol Lett
, vol.115
, Issue.1
, pp. 33-42
-
-
Weide, B.1
Garbe, C.2
Rammensee, H.G.3
Pascolo, S.4
-
120
-
-
2942559009
-
Cancer immunotherapy with mRNA transfected dendritic cells
-
Gilboa E, Vieweg J. Cancer immunotherapy with mRNA transfected dendritic cells. Immunol Rev 2004; 199: 251-63.
-
(2004)
Immunol Rev
, vol.199
, pp. 251-263
-
-
Gilboa, E.1
Vieweg, J.2
-
121
-
-
65249088470
-
Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients
-
Verdijk P, Aarntzen EH, Lesterhuis WJ, Boullart AC, Kok E, van Rossum MM, et al. Limited amounts of dendritic cells migrate into the T-cell area of lymph nodes but have high immune activating potential in melanoma patients. Clin Cancer Res 2009; 15(7): 2531-40.
-
(2009)
Clin Cancer Res
, vol.15
, Issue.7
, pp. 2531-2540
-
-
Verdijk, P.1
Aarntzen, E.H.2
Lesterhuis, W.J.3
Boullart, A.C.4
Kok, E.5
van Rossum, M.M.6
-
122
-
-
33746910738
-
Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA
-
Kyte JA, Mu L, Aamdal S, Kvalheim G, Dueland S, Hauser M, et al. Phase I/II trial of melanoma therapy with dendritic cells transfected with autologous tumor-mRNA. Cancer Gene Ther 2006; 13(10): 905-18.
-
(2006)
Cancer Gene Ther
, vol.13
, Issue.10
, pp. 905-918
-
-
Kyte, J.A.1
Mu, L.2
Aamdal, S.3
Kvalheim, G.4
Dueland, S.5
Hauser, M.6
-
123
-
-
27144507469
-
Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients
-
Mu LJ, Kyte JA, Kvalheim G, Aamdal S, Dueland S, Hauser M, et al. Immunotherapy with allotumour mRNA-transfected dendritic cells in androgen-resistant prostate cancer patients. Br J Cancer 2005; 93(7): 749-56.
-
(2005)
Br J Cancer
, vol.93
, Issue.7
, pp. 749-756
-
-
Mu, L.J.1
Kyte, J.A.2
Kvalheim, G.3
Aamdal, S.4
Dueland, S.5
Hauser, M.6
-
124
-
-
0033565923
-
Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration
-
Eggert AA, Schreurs MW, Boerman OC, Oyen WJ, de Boer AJ, Punt CJ, et al. Biodistribution and vaccine efficiency of murine dendritic cells are dependent on the route of administration. Cancer Res 1999; 59(14): 3340-5.
-
(1999)
Cancer Res
, vol.59
, Issue.14
, pp. 3340-3345
-
-
Eggert, A.A.1
Schreurs, M.W.2
Boerman, O.C.3
Oyen, W.J.4
de Boer, A.J.5
Punt, C.J.6
-
125
-
-
0025231388
-
Direct gene transfer into mouse muscle in vivo
-
Wolff JA, Malone RW, Williams P, Chong W, Acsadi G, Jani A, et al. Direct gene transfer into mouse muscle in vivo. Science 1990; 247(4949 Pt 1): 1465-8.
-
(1990)
Science
, vol.247
, Issue.4949 Pt 1
, pp. 1465-1468
-
-
Wolff, J.A.1
Malone, R.W.2
Williams, P.3
Chong, W.4
Acsadi, G.5
Jani, A.6
-
126
-
-
78549283854
-
Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity
-
Kreiter S, Selmi A, Diken M, Koslowski M, Britten CM, Huber C, et al. Intranodal vaccination with naked antigen-encoding RNA elicits potent prophylactic and therapeutic antitumoral immunity. Cancer Res 2010; 70(22): 9031-40.
-
(2010)
Cancer Res
, vol.70
, Issue.22
, pp. 9031-9040
-
-
Kreiter, S.1
Selmi, A.2
Diken, M.3
Koslowski, M.4
Britten, C.M.5
Huber, C.6
-
127
-
-
0037342270
-
Quantitating protein synthesis, degradation, and endogenous antigen processing
-
Princiotta MF, Finzi D, Qian SB, Gibbs J, Schuchmann S, Buttgereit F, et al. Quantitating protein synthesis, degradation, and endogenous antigen processing. Immunity 2003; 18(3): 343-54.
-
(2003)
Immunity
, vol.18
, Issue.3
, pp. 343-354
-
-
Princiotta, M.F.1
Finzi, D.2
Qian, S.B.3
Gibbs, J.4
Schuchmann, S.5
Buttgereit, F.6
-
128
-
-
34247517688
-
The adjuvant mechanism of cationic dimethyldioctadecylammonium liposomes
-
Korsholm KS, Agger EM, Foged C, Christensen D, Dietrich J, Andersen CS, et al. The adjuvant mechanism of cationic dimethyldioctadecylammonium liposomes. Immunology 2007; 121(2): 216-26.
-
(2007)
Immunology
, vol.121
, Issue.2
, pp. 216-226
-
-
Korsholm, K.S.1
Agger, E.M.2
Foged, C.3
Christensen, D.4
Dietrich, J.5
Andersen, C.S.6
-
129
-
-
21044440406
-
Toll-like receptor-dependent activation of several human blood cell types by protamine-condensed mRNA
-
Scheel B, Teufel R, Probst J, Carralot JP, Geginat J, Radsak M, et al. Toll-like receptor-dependent activation of several human blood cell types by protamine-condensed mRNA. Eur J Immunol 2005; 35(5): 1557-66.
-
(2005)
Eur J Immunol
, vol.35
, Issue.5
, pp. 1557-1566
-
-
Scheel, B.1
Teufel, R.2
Probst, J.3
Carralot, J.P.4
Geginat, J.5
Radsak, M.6
-
130
-
-
15244342229
-
Effect of synthetic lipopeptides formulated in liposomes on the maturation of human dendritic cells
-
Espuelas S, Roth A, Thumann C, Frisch B, Schuber F. Effect of synthetic lipopeptides formulated in liposomes on the maturation of human dendritic cells. Mol Immunol 2005; 42(6): 721-9.
-
(2005)
Mol Immunol
, vol.42
, Issue.6
, pp. 721-729
-
-
Espuelas, S.1
Roth, A.2
Thumann, C.3
Frisch, B.4
Schuber, F.5
-
131
-
-
0028965192
-
Characterization of a messenger RNA polynucleotide vaccine vector
-
Conry RM, LoBuglio AF, Wright M, Sumerel L, Pike MJ, Johanning F, et al. Characterization of a messenger RNA polynucleotide vaccine vector. Cancer Res 1995; 55(7): 1397-400.
-
(1995)
Cancer Res
, vol.55
, Issue.7
, pp. 1397-1400
-
-
Conry, R.M.1
Lobuglio, A.F.2
Wright, M.3
Sumerel, L.4
Pike, M.J.5
Johanning, F.6
-
132
-
-
34447633941
-
Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent
-
Probst J, Weide B, Scheel B, Pichler BJ, Hoerr I, Rammensee HG, et al. Spontaneous cellular uptake of exogenous messenger RNA in vivo is nucleic acid-specific, saturable and ion dependent. Gene Ther 2007; 14(15): 1175-80.
-
(2007)
Gene Ther
, vol.14
, Issue.15
, pp. 1175-1180
-
-
Probst, J.1
Weide, B.2
Scheel, B.3
Pichler, B.J.4
Hoerr, I.5
Rammensee, H.G.6
-
133
-
-
79960145796
-
Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation
-
Diken M, Kreiter S, Selmi A, Britten CM, Huber C, Tureci O, et al. Selective uptake of naked vaccine RNA by dendritic cells is driven by macropinocytosis and abrogated upon DC maturation. Gene Ther 2011; 18(7): 702-8.
-
(2011)
Gene Ther
, vol.18
, Issue.7
, pp. 702-708
-
-
Diken, M.1
Kreiter, S.2
Selmi, A.3
Britten, C.M.4
Huber, C.5
Tureci, O.6
-
134
-
-
84859417996
-
Preclinical evaluation of TriMix and antigen mRNA-based antitumor therapy
-
Van LS, Goyvaerts C, Maenhout S, Goethals L, Disy A, Benteyn D, et al. Preclinical evaluation of TriMix and antigen mRNA-based antitumor therapy. Cancer Res 2012; 72(7): 1661-71.
-
(2012)
Cancer Res
, vol.72
, Issue.7
, pp. 1661-1671
-
-
Van, L.S.1
Goyvaerts, C.2
Maenhout, S.3
Goethals, L.4
Disy, A.5
Benteyn, D.6
-
135
-
-
55749108698
-
Modification of CEA with both CRT and TAT PTD induces potent anti-tumor immune responses in RNA-pulsed DC vaccination
-
Kim SG, Park MY, Kim CH, Sohn HJ, Kim HS, Park JS, et al. Modification of CEA with both CRT and TAT PTD induces potent anti-tumor immune responses in RNA-pulsed DC vaccination. Vaccine 2008; 26(50): 6433-40.
-
(2008)
Vaccine
, vol.26
, Issue.50
, pp. 6433-6440
-
-
Kim, S.G.1
Park, M.Y.2
Kim, C.H.3
Sohn, H.J.4
Kim, H.S.5
Park, J.S.6
-
136
-
-
38949169532
-
Tumor vaccine therapy against recrudescent tumor using dendritic cells simultaneously transfected with tumor RNA and granulocyte macrophage colony-stimulating factor RNA
-
Naka T, Iwahashi M, Nakamura M, Ojima T, Nakamori M, Ueda K, et al. Tumor vaccine therapy against recrudescent tumor using dendritic cells simultaneously transfected with tumor RNA and granulocyte macrophage colony-stimulating factor RNA. Cancer Sci 2008; 99(2): 407-13.
-
(2008)
Cancer Sci
, vol.99
, Issue.2
, pp. 407-413
-
-
Naka, T.1
Iwahashi, M.2
Nakamura, M.3
Ojima, T.4
Nakamori, M.5
Ueda, K.6
-
137
-
-
0029839058
-
Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo
-
Boczkowski D, Nair SK, Snyder D, Gilboa E. Dendritic cells pulsed with RNA are potent antigen-presenting cells in vitro and in vivo. J Exp Med 1996; 184(2): 465-72.
-
(1996)
J Exp Med
, vol.184
, Issue.2
, pp. 465-472
-
-
Boczkowski, D.1
Nair, S.K.2
Snyder, D.3
Gilboa, E.4
-
138
-
-
0036167308
-
Autologous dendritic cells transfected with prostatespecific antigen RNA stimulate CTL responses against metastatic prostate tumors
-
Heiser A, Coleman D, Dannull J, Yancey D, Maurice MA, Lallas CD, et al. Autologous dendritic cells transfected with prostatespecific antigen RNA stimulate CTL responses against metastatic prostate tumors. J Clin Invest 2002; 109(3): 409-17.
-
(2002)
J Clin Invest
, vol.109
, Issue.3
, pp. 409-417
-
-
Heiser, A.1
Coleman, D.2
Dannull, J.3
Yancey, D.4
Maurice, M.A.5
Lallas, C.D.6
-
139
-
-
79957732443
-
Tumor vaccination using messenger RNA: Prospects of a future therapy
-
Kreiter S, Diken M, Selmi A, Tureci O, Sahin U. Tumor vaccination using messenger RNA: prospects of a future therapy. Curr Opin Immunol 2011; 23(3): 399-406.
-
(2011)
Curr Opin Immunol
, vol.23
, Issue.3
, pp. 399-406
-
-
Kreiter, S.1
Diken, M.2
Selmi, A.3
Tureci, O.4
Sahin, U.5
-
141
-
-
4644324025
-
Cancer immunotherapy: Moving beyond current vaccines
-
Rosenberg SA, Yang JC, Restifo NP. Cancer immunotherapy: moving beyond current vaccines. Nat Med 2004; 10(9): 909-15.
-
(2004)
Nat Med
, vol.10
, Issue.9
, pp. 909-915
-
-
Rosenberg, S.A.1
Yang, J.C.2
Restifo, N.P.3
-
142
-
-
44949195901
-
Results of the first phase I/II clinical vaccination trial with direct injection of mRNA
-
Weide B, Carralot JP, Reese A, Scheel B, Eigentler TK, Hoerr I, et al. Results of the first phase I/II clinical vaccination trial with direct injection of mRNA. J Immunother 2008; 31(2): 180-8.
-
(2008)
J Immunother
, vol.31
, Issue.2
, pp. 180-188
-
-
Weide, B.1
Carralot, J.P.2
Reese, A.3
Scheel, B.4
Eigentler, T.K.5
Hoerr, I.6
-
143
-
-
79955630363
-
Intradermal vaccinations with RNA coding for TAA generate CD8+ and CD4+ immune responses and induce clinical benefit in vaccinated patients
-
Rittig SM, Haentschel M, Weimer KJ, Heine A, Muller MR, Brugger W, et al. Intradermal vaccinations with RNA coding for TAA generate CD8+ and CD4+ immune responses and induce clinical benefit in vaccinated patients. Mol Ther 2011; 19(5): 990-9.
-
(2011)
Mol Ther
, vol.19
, Issue.5
, pp. 990-999
-
-
Rittig, S.M.1
Haentschel, M.2
Weimer, K.J.3
Heine, A.4
Muller, M.R.5
Brugger, W.6
-
144
-
-
67651152679
-
Direct injection of protamine-protected mRNA: Results of a phase 1/2 vaccination trial in metastatic melanoma patients
-
Weide B, Pascolo S, Scheel B, Derhovanessian E, Pflugfelder A, Eigentler TK, et al. Direct injection of protamine-protected mRNA: results of a phase 1/2 vaccination trial in metastatic melanoma patients. J Immunother 2009; 32(5): 498-507.
-
(2009)
J Immunother
, vol.32
, Issue.5
, pp. 498-507
-
-
Weide, B.1
Pascolo, S.2
Scheel, B.3
Derhovanessian, E.4
Pflugfelder, A.5
Eigentler, T.K.6
-
145
-
-
73449132930
-
Immunotherapy of human cancers using gene modified T lymphocytes
-
Vera JF, Brenner MK, Dotti G. Immunotherapy of human cancers using gene modified T lymphocytes. Curr Gene Ther 2009; 9(5): 396-408.
-
(2009)
Curr Gene Ther
, vol.9
, Issue.5
, pp. 396-408
-
-
Vera, J.F.1
Brenner, M.K.2
Dotti, G.3
-
146
-
-
79960008541
-
Prospects and limitations of T cell receptor gene therapy
-
Jorritsma A, Schotte R, Coccoris M, de Witte MA, Schumacher TN. Prospects and limitations of T cell receptor gene therapy. Curr Gene Ther 2011; 11(4): 276-87.
-
(2011)
Curr Gene Ther
, vol.11
, Issue.4
, pp. 276-287
-
-
Jorritsma, A.1
Schotte, R.2
Coccoris, M.3
de Witte, M.A.4
Schumacher, T.N.5
-
147
-
-
0036635506
-
T-cell-receptor gene therapy
-
Schumacher TN. T-cell-receptor gene therapy. Nat Rev Immunol 2002; 2(7): 512-9.
-
(2002)
Nat Rev Immunol
, vol.2
, Issue.7
, pp. 512-519
-
-
Schumacher, T.N.1
-
148
-
-
77950961198
-
Building better chimeric antigen receptors for adoptive T cell therapy
-
Bridgeman JS, Hawkins RE, Hombach AA, Abken H, Gilham DE. Building better chimeric antigen receptors for adoptive T cell therapy. Curr Gene Ther 2010; 10(2): 77-90.
-
(2010)
Curr Gene Ther
, vol.10
, Issue.2
, pp. 77-90
-
-
Bridgeman, J.S.1
Hawkins, R.E.2
Hombach, A.A.3
Abken, H.4
Gilham, D.E.5
-
149
-
-
0033168142
-
Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity
-
Clay TM, Custer MC, Sachs J, Hwu P, Rosenberg SA, Nishimura MI. Efficient transfer of a tumor antigen-reactive TCR to human peripheral blood lymphocytes confers anti-tumor reactivity. J Immunol 1999; 163(1): 507-13.
-
(1999)
J Immunol
, vol.163
, Issue.1
, pp. 507-513
-
-
Clay, T.M.1
Custer, M.C.2
Sachs, J.3
Hwu, P.4
Rosenberg, S.A.5
Nishimura, M.I.6
-
150
-
-
0034769412
-
Immunotherapy through TCR gene transfer
-
Kessels HW, Wolkers MC, Van B, Van V, Schumacher TN. Immunotherapy through TCR gene transfer. Nat Immunol 2001; 2(10): 957-61.
-
(2001)
Nat Immunol
, vol.2
, Issue.10
, pp. 957-961
-
-
Kessels, H.W.1
Wolkers, M.C.2
Van, B.3
Van, V.4
Schumacher, T.N.5
-
151
-
-
33749624177
-
Cancer regression in patients after transfer of genetically engineered lymphocytes
-
Morgan RA, Dudley ME, Wunderlich JR, Hughes MS, Yang JC, Sherry RM, et al. Cancer regression in patients after transfer of genetically engineered lymphocytes. Science 2006; 314(5796): 126-9.
-
(2006)
Science
, vol.314
, Issue.5796
, pp. 126-129
-
-
Morgan, R.A.1
Dudley, M.E.2
Wunderlich, J.R.3
Hughes, M.S.4
Yang, J.C.5
Sherry, R.M.6
-
152
-
-
70149114880
-
Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen
-
Johnson LA, Morgan RA, Dudley ME, Cassard L, Yang JC, Hughes MS, et al. Gene therapy with human and mouse T-cell receptors mediates cancer regression and targets normal tissues expressing cognate antigen. Blood 2009; 114(3): 535-46.
-
(2009)
Blood
, vol.114
, Issue.3
, pp. 535-546
-
-
Johnson, L.A.1
Morgan, R.A.2
Dudley, M.E.3
Cassard, L.4
Yang, J.C.5
Hughes, M.S.6
-
153
-
-
79952187823
-
T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis
-
Parkhurst MR, Yang JC, Langan RC, Dudley ME, Nathan DA, Feldman SA, et al. T cells targeting carcinoembryonic antigen can mediate regression of metastatic colorectal cancer but induce severe transient colitis. Mol Ther 2011; 19(3): 620-6.
-
(2011)
Mol Ther
, vol.19
, Issue.3
, pp. 620-626
-
-
Parkhurst, M.R.1
Yang, J.C.2
Langan, R.C.3
Dudley, M.E.4
Nathan, D.A.5
Feldman, S.A.6
-
154
-
-
79952304769
-
Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1
-
Robbins PF, Morgan RA, Feldman SA, Yang JC, Sherry RM, Dudley ME, et al. Tumor Regression in Patients With Metastatic Synovial Cell Sarcoma and Melanoma Using Genetically Engineered Lymphocytes Reactive With NY-ESO-1. J Clin Oncol 2011.
-
(2011)
J Clin Oncol
-
-
Robbins, P.F.1
Morgan, R.A.2
Feldman, S.A.3
Yang, J.C.4
Sherry, R.M.5
Dudley, M.E.6
-
155
-
-
50549096284
-
Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells
-
Till BG, Jensen MC, Wang J, Chen EY, Wood BL, Greisman HA, et al. Adoptive immunotherapy for indolent non-Hodgkin lymphoma and mantle cell lymphoma using genetically modified autologous CD20-specific T cells. Blood 2008; 112(6): 2261-71.
-
(2008)
Blood
, vol.112
, Issue.6
, pp. 2261-2271
-
-
Till, B.G.1
Jensen, M.C.2
Wang, J.3
Chen, E.Y.4
Wood, B.L.5
Greisman, H.A.6
-
156
-
-
80051775476
-
T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia
-
Kalos M, Levine BL, Porter DL, Katz S, Grupp SA, Bagg A, et al. T cells with chimeric antigen receptors have potent antitumor effects and can establish memory in patients with advanced leukemia. Sci Transl Med 2011; 3(95): 95ra73.
-
(2011)
Sci Transl Med
, vol.3
, Issue.95
-
-
Kalos, M.1
Levine, B.L.2
Porter, D.L.3
Katz, S.4
Grupp, S.A.5
Bagg, A.6
-
157
-
-
80054680991
-
Treating cancer with genetically engineered T cells
-
Park TS, Rosenberg SA, Morgan RA. Treating cancer with genetically engineered T cells. Trends Biotechnol 2011; 29(11): 550-7.
-
(2011)
Trends Biotechnol
, vol.29
, Issue.11
, pp. 550-557
-
-
Park, T.S.1
Rosenberg, S.A.2
Morgan, R.A.3
-
158
-
-
70349438847
-
Engineering lymphocyte subsets: Tools, trials and tribulations
-
June CH, Blazar BR, Riley JL. Engineering lymphocyte subsets: tools, trials and tribulations. Nat Rev Immunol 2009; 9(10): 704-16.
-
(2009)
Nat Rev Immunol
, vol.9
, Issue.10
, pp. 704-716
-
-
June, C.H.1
Blazar, B.R.2
Riley, J.L.3
-
159
-
-
60649103432
-
Clinical application of lentiviral vectors - concepts and practice
-
Schambach A, Baum C. Clinical application of lentiviral vectors - concepts and practice. Curr Gene Ther 2008; 8(6): 474-82.
-
(2008)
Curr Gene Ther
, vol.8
, Issue.6
, pp. 474-482
-
-
Schambach, A.1
Baum, C.2
-
160
-
-
84860718270
-
Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells
-
Scholler J, Brady TL, Binder-Scholl G, Hwang WT, Plesa G, Hege KM, et al. Decade-long safety and function of retroviral-modified chimeric antigen receptor T cells. Sci Transl Med 2012; 4(132): 132ra53.
-
(2012)
Sci Transl Med
, vol.4
, Issue.132
-
-
Scholler, J.1
Brady, T.L.2
Binder-Scholl, G.3
Hwang, W.T.4
Plesa, G.5
Hege, K.M.6
-
161
-
-
77950475517
-
Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2
-
Morgan RA, Yang JC, Kitano M, Dudley ME, Laurencot CM, Rosenberg SA. Case report of a serious adverse event following the administration of T cells transduced with a chimeric antigen receptor recognizing ERBB2. Mol Ther 2010; 18(4): 843-51.
-
(2010)
Mol Ther
, vol.18
, Issue.4
, pp. 843-851
-
-
Morgan, R.A.1
Yang, J.C.2
Kitano, M.3
Dudley, M.E.4
Laurencot, C.M.5
Rosenberg, S.A.6
-
162
-
-
28844442400
-
High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation
-
Zhao Y, Zheng Z, Cohen CJ, Gattinoni L, Palmer DC, Restifo NP, et al. High-efficiency transfection of primary human and mouse T lymphocytes using RNA electroporation. Mol Ther 2006; 13(1): 151-9.
-
(2006)
Mol Ther
, vol.13
, Issue.1
, pp. 151-159
-
-
Zhao, Y.1
Zheng, Z.2
Cohen, C.J.3
Gattinoni, L.4
Palmer, D.C.5
Restifo, N.P.6
-
163
-
-
33646145685
-
A new way to generate cytolytic tumor-specific T cells: Electroporation of RNA coding for a T cell receptor into T lymphocytes
-
Schaft N, Dorrie J, Muller I, Beck V, Baumann S, Schunder T, et al. A new way to generate cytolytic tumor-specific T cells: electroporation of RNA coding for a T cell receptor into T lymphocytes. Cancer Immunol Immunother 2006; 55(9): 1132-41.
-
(2006)
Cancer Immunol Immunother
, vol.55
, Issue.9
, pp. 1132-1141
-
-
Schaft, N.1
Dorrie, J.2
Muller, I.3
Beck, V.4
Baumann, S.5
Schunder, T.6
-
164
-
-
67349189462
-
Adoptive immunotherapy using human peripheral blood lymphocytes transferred with RNA encoding Her-2/neu-specific chimeric immune receptor in ovarian cancer xenograft
-
Yoon SH, Lee JM, Cho HI, Kim H, Kim HS, Park MY, et al. Adoptive immunotherapy using human peripheral blood lymphocytes transferred with RNA encoding Her-2/neu-specific chimeric immune receptor in ovarian cancer xenograft. Cancer Gene Ther 2009; 16: 489-97.
-
(2009)
Cancer Gene Ther
, vol.16
, pp. 489-497
-
-
Yoon, S.H.1
Lee, J.M.2
Cho, H.I.3
Kim, H.4
Kim, H.S.5
Park, M.Y.6
-
165
-
-
58849111711
-
Chimeric receptor mRNA transfection as a tool to generate antineoplastic lymphocytes
-
Rabinovich PM, Komarovskaya ME, Wrzesinski SH, Alderman JL, Budak-Alpdogan T, Karpikov A, et al. Chimeric receptor mRNA transfection as a tool to generate antineoplastic lymphocytes. Hum Gene Ther 2009; 20(1): 51-61.
-
(2009)
Hum Gene Ther
, vol.20
, Issue.1
, pp. 51-61
-
-
Rabinovich, P.M.1
Komarovskaya, M.E.2
Wrzesinski, S.H.3
Alderman, J.L.4
Budak-Alpdogan, T.5
Karpikov, A.6
-
166
-
-
78549253550
-
Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor
-
Zhao Y, Moon E, Carpenito C, Paulos CM, Liu X, Brennan AL, et al. Multiple injections of electroporated autologous T cells expressing a chimeric antigen receptor mediate regression of human disseminated tumor. Cancer Res 2010; 70(22): 9053-61.
-
(2010)
Cancer Res
, vol.70
, Issue.22
, pp. 9053-9061
-
-
Zhao, Y.1
Moon, E.2
Carpenito, C.3
Paulos, C.M.4
Liu, X.5
Brennan, A.L.6
-
167
-
-
83455213653
-
Treatment of advanced leukemia in mice with mRNA engineered T cells
-
Barrett DM, Zhao Y, Liu X, Jiang S, Carpenito C, Kalos M, et al. Treatment of advanced leukemia in mice with mRNA engineered T cells. Hum Gene Ther 2011; 22(12): 1575-86.
-
(2011)
Hum Gene Ther
, vol.22
, Issue.12
, pp. 1575-1586
-
-
Barrett, D.M.1
Zhao, Y.2
Liu, X.3
Jiang, S.4
Carpenito, C.5
Kalos, M.6
-
168
-
-
77956884540
-
Direct and indirect antitumor effects by human peripheral blood lymphocytes expressing both chimeric immune receptor and interleukin-2 in ovarian cancer xenograft model
-
Lee JM, Yoon SH, Kim HS, Kim SY, Sohn HJ, Oh ST, et al. Direct and indirect antitumor effects by human peripheral blood lymphocytes expressing both chimeric immune receptor and interleukin-2 in ovarian cancer xenograft model. Cancer Gene Ther 2010; 17(10): 742-50.
-
(2010)
Cancer Gene Ther
, vol.17
, Issue.10
, pp. 742-750
-
-
Lee, J.M.1
Yoon, S.H.2
Kim, H.S.3
Kim, S.Y.4
Sohn, H.J.5
Oh, S.T.6
-
169
-
-
84859379903
-
Mesothelin-targeted agents in clinical trials and in preclinical development
-
Kelly RJ, Sharon E, Pastan I, Hassan R. Mesothelin-targeted agents in clinical trials and in preclinical development. Mol Cancer Ther 2012; 11(3): 517-25.
-
(2012)
Mol Cancer Ther
, vol.11
, Issue.3
, pp. 517-525
-
-
Kelly, R.J.1
Sharon, E.2
Pastan, I.3
Hassan, R.4
-
170
-
-
33747195353
-
Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors
-
Takahashi K, Yamanaka S. Induction of pluripotent stem cells from mouse embryonic and adult fibroblast cultures by defined factors. Cell 2006; 126(4): 663-76.
-
(2006)
Cell
, vol.126
, Issue.4
, pp. 663-676
-
-
Takahashi, K.1
Yamanaka, S.2
-
171
-
-
84856007232
-
The promise of induced pluripotent stem cells in research and therapy
-
Robinton DA, Daley GQ. The promise of induced pluripotent stem cells in research and therapy. Nature 2012; 481(7381): 295-305.
-
(2012)
Nature
, vol.481
, Issue.7381
, pp. 295-305
-
-
Robinton, D.A.1
Daley, G.Q.2
-
172
-
-
34249880066
-
Generation of germlinecompetent induced pluripotent stem cells
-
Okita K, Ichisaka T, Yamanaka S. Generation of germlinecompetent induced pluripotent stem cells. Nature 2007; 448(7151): 313-7.
-
(2007)
Nature
, vol.448
, Issue.7151
, pp. 313-317
-
-
Okita, K.1
Ichisaka, T.2
Yamanaka, S.3
-
173
-
-
80055113187
-
Activation of pluripotency-associated genes in mouse embryonic fibroblasts by non-viral transfection with in vitroderived mRNAs encoding Oct4, Sox2, Klf4 and cMyc
-
Tavernier G, Wolfrum K, Demeester J, De Smedt SC, Adjaye J, Rejman J. Activation of pluripotency-associated genes in mouse embryonic fibroblasts by non-viral transfection with in vitroderived mRNAs encoding Oct4, Sox2, Klf4 and cMyc. Biomaterials 2012; 33(2): 412-7.
-
(2012)
Biomaterials
, vol.33
, Issue.2
, pp. 412-417
-
-
Tavernier, G.1
Wolfrum, K.2
Demeester, J.3
de Smedt, S.C.4
Adjaye, J.5
Rejman, J.6
-
174
-
-
78649471039
-
Direct conversion of human fibroblasts to multilineage blood progenitors
-
Szabo E, Rampalli S, Risueno RM, Schnerch A, Mitchell R, Fiebig-Comyn A, et al. Direct conversion of human fibroblasts to multilineage blood progenitors. Nature 2010; 468(7323): 521-6.
-
(2010)
Nature
, vol.468
, Issue.7323
, pp. 521-526
-
-
Szabo, E.1
Rampalli, S.2
Risueno, R.M.3
Schnerch, A.4
Mitchell, R.5
Fiebig-Comyn, A.6
-
175
-
-
77649162059
-
Direct conversion of fibroblasts to functional neurons by defined factors
-
Vierbuchen T, Ostermeier A, Pang ZP, Kokubu Y, Sudhof TC, Wernig M. Direct conversion of fibroblasts to functional neurons by defined factors. Nature 2010; 463(7284): 1035-41.
-
(2010)
Nature
, vol.463
, Issue.7284
, pp. 1035-1041
-
-
Vierbuchen, T.1
Ostermeier, A.2
Pang, Z.P.3
Kokubu, Y.4
Sudhof, T.C.5
Wernig, M.6
-
176
-
-
79951711771
-
Zinc-finger nucleases: A panoramic view
-
Carroll D. Zinc-finger nucleases: a panoramic view. Curr Gene Ther 2011; 11(1): 2-10.
-
(2011)
Curr Gene Ther
, vol.11
, Issue.1
, pp. 2-10
-
-
Carroll, D.1
-
177
-
-
79951699566
-
Zinc-finger nuclease based genome surgery: It's all about specificity
-
Handel EM, Cathomen T. Zinc-finger nuclease based genome surgery: it's all about specificity. Curr Gene Ther 2011; 11(1): 28-37.
-
(2011)
Curr Gene Ther
, vol.11
, Issue.1
, pp. 28-37
-
-
Handel, E.M.1
Cathomen, T.2
-
179
-
-
44949155482
-
Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases
-
Doyon Y, McCammon JM, Miller JC, Faraji F, Ngo C, Katibah GE, et al. Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases. Nat Biotechnol 2008; 26(6): 702-8.
-
(2008)
Nat Biotechnol
, vol.26
, Issue.6
, pp. 702-708
-
-
Doyon, Y.1
McCammon, J.M.2
Miller, J.C.3
Faraji, F.4
Ngo, C.5
Katibah, G.E.6
-
180
-
-
67749106611
-
Knockout rats via embryo microinjection of zinc-finger nucleases
-
Geurts AM, Cost GJ, Freyvert Y, Zeitler B, Miller JC, Choi VM, et al. Knockout rats via embryo microinjection of zinc-finger nucleases. Science 2009; 325(5939): 433.
-
(2009)
Science
, vol.325
, Issue.5939
, pp. 433
-
-
Geurts, A.M.1
Cost, G.J.2
Freyvert, Y.3
Zeitler, B.4
Miller, J.C.5
Choi, V.M.6
-
181
-
-
0034777146
-
piggyBac-mediated transposition in Drosophila melanogaster: An evaluation of the use of constitutive promoters to control transposase gene expression
-
Li X, Heinrich JC, Scott MJ. piggyBac-mediated transposition in Drosophila melanogaster: an evaluation of the use of constitutive promoters to control transposase gene expression. Insect Mol Biol 2001; 10(5): 447-55.
-
(2001)
Insect Mol Biol
, vol.10
, Issue.5
, pp. 447-455
-
-
Li, X.1
Heinrich, J.C.2
Scott, M.J.3
-
182
-
-
34250786956
-
Messenger RNA as a source of transposase for sleeping beauty transposon-mediated correction of hereditary tyrosinemia type I
-
Wilber A, Wangensteen KJ, Chen Y, Zhuo L, Frandsen JL, Bell JB, et al. Messenger RNA as a source of transposase for sleeping beauty transposon-mediated correction of hereditary tyrosinemia type I. Mol Ther 2007; 15(7): 1280-7.
-
(2007)
Mol Ther
, vol.15
, Issue.7
, pp. 1280-1287
-
-
Wilber, A.1
Wangensteen, K.J.2
Chen, Y.3
Zhuo, L.4
Frandsen, J.L.5
Bell, J.B.6
-
183
-
-
32944463921
-
RNA as a source of transposase for Sleeping Beautymediated gene insertion and expression in somatic cells and tissues
-
Wilber A, Frandsen JL, Geurts JL, Largaespada DA, Hackett PB, McIvor RS. RNA as a source of transposase for Sleeping Beautymediated gene insertion and expression in somatic cells and tissues. Mol Ther 2006; 13(3): 625-30.
-
(2006)
Mol Ther
, vol.13
, Issue.3
, pp. 625-630
-
-
Wilber, A.1
Frandsen, J.L.2
Geurts, J.L.3
Largaespada, D.A.4
Hackett, P.B.5
McIvor, R.S.6
-
184
-
-
84860539841
-
Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin
-
Kariko K, Muramatsu H, Keller JM, Weissman D. Increased erythropoiesis in mice injected with submicrogram quantities of pseudouridine-containing mRNA encoding erythropoietin. Mol Ther 2012; 20(5): 948-53.
-
(2012)
Mol Ther
, vol.20
, Issue.5
, pp. 948-953
-
-
Kariko, K.1
Muramatsu, H.2
Keller, J.M.3
Weissman, D.4
|