메뉴 건너뛰기




Volumn 17, Issue 4, 2010, Pages 439-447

Progress and prospects: Nuclear import of nonviral vectors

Author keywords

Importin; Karyopherin; Nonviral gene transfer; Nuclear localization signal; Nuclear pore complex; Plasmid

Indexed keywords

CARRIER PROTEIN; CELL PROTEIN; CHAPERONE; CYTOSKELETON PROTEIN; DNA BINDING PROTEIN; GENOMIC DNA; HISTONE; HISTONE H2B; IMMEDIATE EARLY PROTEIN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; KARYOPHERIN; LIGAND; LIPOSOME; MACROGOL; NAKED DNA; NANOPARTICLE; NUCLEAR PROTEIN; OCTAMER TRANSCRIPTION FACTOR 1; POLYAMIDOAMINE; POLYETHYLENEIMINE; POLYLYSINE; POLYMER; RAN PROTEIN; RIBOSOME PROTEIN; THYMIDINE KINASE; TRANSCRIPTION FACTOR AP 1; TRANSCRIPTION FACTOR AP 2; ZINC FINGER PROTEIN;

EID: 77950857472     PISSN: 09697128     EISSN: 14765462     Source Type: Journal    
DOI: 10.1038/gt.2010.31     Document Type: Review
Times cited : (176)

References (19)
  • 1
    • 65749110643 scopus 로고    scopus 로고
    • Tissue-specific and transcription factormediated nuclear entry of DNA
    • Miller AM, Dean DA. Tissue-specific and transcription factormediated nuclear entry of DNA. Adv Drug Deliv Rev 2009; 61: 603-613.
    • (2009) Adv Drug Deliv Rev , vol.61 , pp. 603-613
    • Miller, A.M.1    Dean, D.A.2
  • 2
    • 62849113646 scopus 로고    scopus 로고
    • Quantification of plasmid DNA copies in the nucleus after lipoplex and polyplex transfection
    • Cohen RN, van der Aa MA, Macaraeg N, Lee AP, Szoka Jr FC. Quantification of plasmid DNA copies in the nucleus after lipoplex and polyplex transfection. J Control Release 2009; 135: 166-174.
    • (2009) J Control Release , vol.135 , pp. 166-174
    • Cohen, R.N.1    Van Der Aa, M.A.2    MacAraeg, N.3    Lee, A.P.4    Szoka Jr., F.C.5
  • 3
    • 75449093579 scopus 로고    scopus 로고
    • The efficiency of nuclear plasmid DNA delivery is a critical determinant of transgene expression at the single cell level
    • Glover DJ, Leyton DL, Moseley GW, Jans DA. The efficiency of nuclear plasmid DNA delivery is a critical determinant of transgene expression at the single cell level. J Gene Med 2010; 12: 77-85.
    • J Gene Med , vol.2010 , Issue.12 , pp. 77-85
    • Glover, D.J.1    Leyton, D.L.2    Moseley, G.W.3    Jans, D.A.4
  • 4
    • 69249222891 scopus 로고    scopus 로고
    • Nuclear localization signals and human disease
    • McLane LM, Corbett AH. Nuclear localization signals and human disease. IUBMB Life 2009; 61: 697-706.
    • (2009) IUBMB Life , vol.61 , pp. 697-706
    • McLane, L.M.1    Corbett, A.H.2
  • 6
    • 47749088627 scopus 로고    scopus 로고
    • Smooth muscle-specific gene delivery in the vasculature based on restriction of DNA nuclear import
    • Young JL, Zimmer WE, Dean DA. Smooth muscle-specific gene delivery in the vasculature based on restriction of DNA nuclear import. Exp Biol Med 2008; 233: 840-848.
    • (2008) Exp Biol Med , vol.233 , pp. 840-848
    • Young, J.L.1    Zimmer, W.E.2    Dean, D.A.3
  • 7
    • 77950861301 scopus 로고    scopus 로고
    • The SP-C promoter facilitates alveolar type II epithelial cell-specific plasmid nuclear import and gene expression
    • e-pub ahead of print
    • Degiulio JV, Kaufman CD, Dean DA. The SP-C promoter facilitates alveolar type II epithelial cell-specific plasmid nuclear import and gene expression. Gene Therapy 2010, (e-pub ahead of print).
    • (2010) Gene Therapy
    • Degiulio, J.V.1    Kaufman, C.D.2    Dean, D.A.3
  • 8
    • 47549103094 scopus 로고    scopus 로고
    • Cell-specific nuclear import of plasmid DNA in smooth muscle requires tissue-specific transcription factors and DNA sequences
    • Miller AM, Dean DA. Cell-specific nuclear import of plasmid DNA in smooth muscle requires tissue-specific transcription factors and DNA sequences. Gene Therapy 2008; 15: 1107-1115.
    • (2008) Gene Therapy , vol.15 , pp. 1107-1115
    • Miller, A.M.1    Dean, D.A.2
  • 9
    • 70449120385 scopus 로고    scopus 로고
    • Identification of protein cofactors necessary for sequence-specific plasmid DNA nuclear import
    • Miller AM, Munkonge FM, Alton EW, Dean DA. Identification of protein cofactors necessary for sequence-specific plasmid DNA nuclear import. Mol Ther 2009; 17: 1897-1903.
    • (2009) Mol Ther , vol.17 , pp. 1897-1903
    • Miller, A.M.1    Munkonge, F.M.2    Alton, E.W.3    Dean, D.A.4
  • 10
    • 70350351352 scopus 로고    scopus 로고
    • Identification and functional characterisation of cytoplasmic determinants of plasmid DNA nuclear import
    • Munkonge FM, Amin V, Hyde SC, Green AM, Pringle IA, Gill DR et al. Identification and functional characterisation of cytoplasmic determinants of plasmid DNA nuclear import. J Biol Chem 2009; 284: 26978-26987.
    • (2009) J Biol Chem , vol.284 , pp. 26978-26987
    • Munkonge, F.M.1    Amin, V.2    Hyde, S.C.3    Green, A.M.4    Pringle, I.A.5    Gill, D.R.6
  • 12
    • 55249114136 scopus 로고    scopus 로고
    • Amphiphilic block copolymers enhance cellular uptake and nuclear entry of polyplex-delivered DNA
    • Yang Z, Sahay G, Sriadibhatla S, Kabanov AV. Amphiphilic block copolymers enhance cellular uptake and nuclear entry of polyplex-delivered DNA. Bioconjug Chem 2008; 19: 1987-1994.
    • (2008) Bioconjug Chem , vol.19 , pp. 1987-1994
    • Yang, Z.1    Sahay, G.2    Sriadibhatla, S.3    Kabanov, A.V.4
  • 13
    • 47249158181 scopus 로고    scopus 로고
    • Nuclear delivery of NFiB-assisted DNA/polymer complexes: Plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging
    • Breuzard G, Tertil M, Goncalves C, Cheradame H, Geguan P, Pichon C et al. Nuclear delivery of NFiB-assisted DNA/polymer complexes: plasmid DNA quantitation by confocal laser scanning microscopy and evidence of nuclear polyplexes by FRET imaging. Nucleic Acids Res 2008; 36: e71.
    • (2008) Nucleic Acids Res , vol.36
    • Breuzard, G.1    Tertil, M.2    Goncalves, C.3    Cheradame, H.4    Geguan, P.5    Pichon, C.6
  • 14
    • 33947212504 scopus 로고    scopus 로고
    • MIDGE/hNIS vaccination generates antigen-associated CD8+ IFN-gamma+ T cells and enhances protective antitumor immunity
    • Choi Y, Jeon YH, Kang JH, Chung JK, Schmidt M, Kim AC. MIDGE/hNIS vaccination generates antigen-associated CD8+ IFN-gamma+ T cells and enhances protective antitumor immunity. Int J Cancer 2007; 120: 1942-1950.
    • (2007) Int J Cancer , vol.120 , pp. 1942-1950
    • Choi, Y.1    Jeon, Y.H.2    Kang, J.H.3    Chung, J.K.4    Schmidt, M.5    Kim, A.C.6
  • 15
    • 57349105135 scopus 로고    scopus 로고
    • Designed multidomain protein as a carrier of nucleic acids into cells
    • Xavier J, Singh S, Dean DA, Rao NM, Gopal V. Designed multidomain protein as a carrier of nucleic acids into cells. J Control Release 2009; 133: 154-160.
    • (2009) J Control Release , vol.133 , pp. 154-160
    • Xavier, J.1    Singh, S.2    Dean, D.A.3    Rao, N.M.4    Gopal, V.5
  • 16
    • 58149183267 scopus 로고    scopus 로고
    • Effect of peptides bearing nuclear localization signals on therapeutic ultrasound mediated gene delivery
    • Duvshani-Eshet M, Keren H, Oz S, Radzishevsky IS, Mor A, Machluf M. Effect of peptides bearing nuclear localization signals on therapeutic ultrasound mediated gene delivery. J Gene Med 2008; 10: 1150-1159.
    • (2008) J Gene Med , vol.10 , pp. 1150-1159
    • Duvshani-Eshet, M.1    Keren, H.2    Oz, S.3    Radzishevsky, I.S.4    Mor, A.5    MacHluf, M.6
  • 17
    • 65949101881 scopus 로고    scopus 로고
    • Dexamethasoneconjugated polyethylenimine as an efficient gene carrier with an anti-apoptotic effect to cardiomyocytes
    • Kim H, Kim HA, Bae YM, Choi JS, Lee M. Dexamethasoneconjugated polyethylenimine as an efficient gene carrier with an anti-apoptotic effect to cardiomyocytes. J Gene Med 2009; 11: 515-522.
    • (2009) J Gene Med , vol.11 , pp. 515-522
    • Kim, H.1    Kim, H.A.2    Bae, Y.M.3    Choi, J.S.4    Lee, M.5
  • 18
    • 38649138015 scopus 로고    scopus 로고
    • Cell surface nucleolin serves as receptor for DNA nanoparticles composed of pegylated polylysine and DNA
    • Chen X, Kube DM, Cooper MJ, Davis PB. Cell surface nucleolin serves as receptor for DNA nanoparticles composed of pegylated polylysine and DNA. Mol Ther 2008; 16: 333-342.
    • (2008) Mol Ther , vol.16 , pp. 333-342
    • Chen, X.1    Kube, D.M.2    Cooper, M.J.3    Davis, P.B.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.