Synthesis and evaluation of 2′-O-allyl substituted dinucleotide cap analog for mRNA translation

Bioorganic and Medicinal Chemistry

Volumn 18, Issue 22, 2010, Pages 8061-8065

  Kore, Anilkumar R ^a   Charles, Irudaya ^a  

^a Life Technologies Corporation   (United States)

Author keywords

2 O Allyl substituted dinucleotide cap analog; Cap analog; Capping efficiency; HeLa cells; In vitro transcription; Luciferase activity; Translation efficiency

Indexed keywords

CAPPED RNA; DINUCLEOTIDE; MESSENGER RNA; RNA POLYMERASE;

ARTICLE; CANCER IMMUNIZATION; CONTROLLED STUDY; DRUG SYNTHESIS; GENE THERAPY; GENETIC TRANSFECTION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; PROTEIN SYNTHESIS; RNA CAPPING; RNA TRANSCRIPTION; RNA TRANSLATION;

DINUCLEOSIDE PHOSPHATES; DNA-DIRECTED RNA POLYMERASES; DRUG DESIGN; HELA CELLS; HUMANS; PROTEIN BIOSYNTHESIS; RNA CAP ANALOGS; RNA, MESSENGER; VIRAL PROTEINS;

EID: 78449258644     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2010.09.013     Document Type: Article

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