Circularization of mRNA by eukaryotic translation initiation factors

Molecular Cell

Volumn 2, Issue 1, 1998, Pages 135-140

  Wells, Sandra E ^a   Hillner, Paul E ^b   Vale, Ronald D ^b   Sachs, Alan B ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

EIF4G1 PROTEIN, HUMAN; EIF4G1 PROTEIN, S CEREVISIAE; FUNGAL PROTEIN; FUNGAL RNA; GLUTATHIONE TRANSFERASE; HYBRID PROTEIN; INITIATION FACTOR; INITIATION FACTOR 4E; INITIATION FACTOR 4G; MESSENGER RNA; PEPTIDE FRAGMENT; POLYADENYLIC ACID BINDING PROTEIN; RNA; RNA BINDING PROTEIN; RNA, CIRCULAR;

ARTICLE; ATOMIC FORCE MICROSCOPY; BIOSYNTHESIS; CHEMISTRY; CONFORMATION; GENETICS; MACROMOLECULE; METABOLISM; PROTEIN SYNTHESIS; SACCHAROMYCES CEREVISIAE; ULTRASTRUCTURE;

EUKARYOTIC INITIATION FACTOR-4E; EUKARYOTIC INITIATION FACTOR-4G; FUNGAL PROTEINS; GLUTATHIONE TRANSFERASE; MACROMOLECULAR SUBSTANCES; MICROSCOPY, ATOMIC FORCE; NUCLEIC ACID CONFORMATION; PEPTIDE FRAGMENTS; PEPTIDE INITIATION FACTORS; POLY(A)-BINDING PROTEINS; PROTEIN BIOSYNTHESIS; RECOMBINANT FUSION PROTEINS; RNA; RNA, FUNGAL; RNA, MESSENGER; RNA-BINDING PROTEINS; SACCHAROMYCES CEREVISIAE;

EID: 0032112017     PISSN: 10972765     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1097-2765(00)80122-7     Document Type: Article

References (30)

1. Altmann, M., Schmitz, N., Berset, C., and Trachsel, H. (1997). A novel inhibitor of cap-dependent translation initiation in yeast: p20 competes with elF4G for binding to elF4E. EMBO J. 16, 1114-1121.
2. Anderson, J., Paddy, M., and Swanson, M. (1993). PUB1 is a major nuclear and cytoplasmic polyadenylated RNA-binding protein in Saccharomyces cerevisiae. Mol. Cell. Biol. 136, 102-112.
3. Christensen, A.K., Kahn, L.E., and Bourne, C.M. (1987). Circular polysemes predominate on the rough endoplasmic reticulum of somatotropes and mammotropes in the rat anterior pituitary. Amer. J. Anat. 178, 1-10.
4. Deardorff, J.A., and Sachs, A.B. (1997). Differential effects of aromatic and charged residue substitutions in the RNA binding domains of the yeast poly(A)-binding protein. J. Mol. Biol. 269, 67-81.
5. Edery, I., Altmann, M., and Sonenberg, N. (1988). High-level synthesis in Escherichia coli of functional cap-binding eukaryotic initiation factor elF-4E and affinity purification using a simplified cap-analog resin. Gene 74, 517-525.
6. Gallie, D.R. (1991). The cap and the poly(A) tail function synergistically to regulate mRNA translational efficiency. Genes Dev. 5, 2108-2116.
7. Goyer, C., Altmann, M., Lee, H.S., Blanc, A., Deshmukh, M., Woolford, J.L, Trachsel, H., and Sonenberg, N. (1993). TIF4631 and TIF4632: two genes encoding the high-molecular weight subunits of the cap-binding protein complex (eukaryotic initiation factor 4F) contain an RNA recognition motif sequence and carry out an essential function. Mol. Cell. Biol. 13, 4860-4874.
8. Haghighat, A., Mader, S., Pause, A., and Sonenberg, N. (1995). Repression of cap-dependent translation by 4E-binding protein 1:competition with p200 for binding to eukaryotic initiation factor-4E. EMBO J. 14, 5701-5709.
9. Hansma, P.K., Cleveland, J.P., Radmacher, M., Walters, D.A., Hillner, P.E., Bezanilla, M., Fritz, M., Vie, D., Hansma, H.G., Prater, C.B., et al. (1994). Tapping mode atomic force microscopy in liquids. Appl. Phys. Lett. 64, 1738-1740.
10. Kasas, S., Thomson, N.H., Smith, B.L., Hansma, H.G., Zhu, X., Guthold, M., Bustamante, C., Kool, E., Kashlev, M., and Hansma, P.K. (1997). Escherichia coli RNA polymerase activity observed using atomic force microscopy. Biochemistry 36, 461-468.
11. Kessler, S.H., and Sachs, A.B. (1998). RNA recognition motif 2 of yeast Pab1p is required for its functional interaction with elF4G. Mol. Cell. Biol. 18, 51-57.
12. Lamphear, B.J., Kirchweger, R., Skern, T., and Rhoads, R.E. (1995). Mapping of functional domains in eukaryotic protein synthesis initiation factor 4G (elF4G) with picornaviral proteases. J. Biol. Chem. 270, 21975-21983.
13. Mader, S., Lee, H., Pause, A., and Sonenberg, N. (1995). The translation initiation factor elF-4E binds to a common motif shared by the translation factor elF-4g and the translational repressors 4E-binding proteins. Mol. Cell. Biol. 15, 4990-4997.
14. Merrick, W.C., and Hershey, J.W.B. (1996). The pathway and mechanism of eukaryotic protein synthesis. In Translational Control, J.W.B. Hershey, M.B. Mathews, and N. Sonenberg, eds. (New York: Cold Spring Harbor Laboratory Press), pp. 31-70.
15. Minich, W.B., Balasta, M.L., Goss, D.L., and Rhoads, R.E. (1994). Chromatographic resolution of in vivo phosphorylated and nonphosphorylated eukaryotic translation initiation factor elF-4E: increased cap affinity of the phosphorylated form. Proc. Natl. Acad. Sci. USA 91, 7668-7672.
16. Morley, S.J., Curtis, P.S., and Pain, V.M. (1997). elF4G: translation's mystery factor begins to yield its secrets. RNA 3, 1085-1104.
17. Munroe, D., and Jacobson, A. (1990). mRNA poly(A) tail, a 3′ enhancer of translation initiation. Mol. Cell. Biol. 10, 3441-3455.
18. Pasquinelli, A.E., Dahlberg, J.E., and Lund, E. (1995). Reverse 5′ caps in RNAs made in vitro by phage RNA polymerases. RNA 1, 957-967.
19. Sachs, A.B. (1990). The role of poly(A) in the translation and stability of mRNA. Curr. Opin. Cell Biol. 2, 1092-1098.
20. Sachs, A.B., and Davis, R.W. (1989). The poly(A) binding protein is required for poly(A) shortening and 60S ribosomal subunit-dependent translation initiation. Cell 58, 857-867.
21. Sachs, A.B., Davis, R.W., and Kornberg, R.D. (1987). A single domain of yeast poly(A)-binding protein is necessary and sufficient for RNA binding and cell viability. Mol. Cell. Biol. 7, 3268-3276.
22. Sachs, A.B., Sarnow, P., and Hentze, M.W. (1997). Starting at the beginning, middle, and end: translation initiation in eukaryotes. Cell 89, 831-838.
23. Sheets, M., Wu, M., and Wickens, M. (1995). Polyadenylation of c-mos mRNA as a control point in Xenopus meiotic maturation. Nature 374, 511-516.
24. Shore, D., and Baldwin, R.L. (1983). Energetics of DNA twisting. J. Mol. Biol. 170, 957-981.
25. Sonenberg, N. (1996). mRNA 5′ cap-binding protein e1F4E and control of cell growth. In Translational Control, J.W.B. Hershey, M.B. Mathews, and N. Sonenberg, eds. (New York: Cold Spring Harbor Laboratory Press), pp. 245-269.
26. Tarun, S.Z., and Sachs, A.B. (1995). A common function for mRNA 5′ and 3′ ends in translation initiation in yeast. Genes Dev. 9, 2997-3007.
27. Tarun, S.Z., and Sachs, A.B. (1996). Association of the yeast poly(A) tail binding protein with translation initiation factor elF-4G. EMBO J. 15, 7168-7177.
28. Tarun, S.Z., and Sachs, A.B. (1997). Binding of elF4E to elF4G represses translation of uncapped mRNa. Mol. Cell. Biol. 17, 6876-6886.
29. Tarun, S.Z., Wells, S.E., Deardorff, J.A., and Sachs, A.B. (1997). Translation initiation factor elF-4G mediates in vitro poly(A) taildependent translation. Proc. Natl. Acad. Sci. USA 94, 9046-9051.
30. Vasilescu, S., Ptushkina, M., Linz, B., Muller, P.P., and McCarthy, J.E.G. (1996). Mutants of eukaryotic initiation factor elF-4E with altered mRNA cap binding specificity reprogram mRNA selection by ribosomes in Saccharomyces cerevisiae. J. Biol. Chem. 271, 7030-7037.