Toll-like receptor-dependent activation of several human blood cell types by protamine-condensed mRNA

European Journal of Immunology

Volumn 35, Issue 5, 2005, Pages 1557-1566

  Scheel, Birgit ^a,b   Teufel, Regina ^a   Probst, Jochen ^b   Carralot, Jean Philippe ^a,b   Geginat, Jens ^c   Radsak, Markus ^b   Jarrossay, David ^c   Wagner, Hermann ^d   Jung, Günther ^e   Rammensee, Hans Georg ^b   Hoerr, Ingmar ^a   Pascolo, Steve ^a,b  

^a CureVac GmbH   (Germany)

^b Interfaculty Institute for Cell Biology   (Germany)

^c INSTITUTE FOR RESEARCH IN BIOMEDICINE   (Switzerland)

^d TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^e UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

B cell; DC; Protamine; RNA; TLR

Indexed keywords

ALPHA INTERFERON; CYTOKINE; MESSENGER RNA; MYELOID DIFFERENTIATION FACTOR 88; PROTAMINE; RNA; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 7; TOLL LIKE RECEPTOR 8; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; B LYMPHOCYTE ACTIVATION; CELL ACTIVATION; CELL CULTURE; CELL STIMULATION; CONTROLLED STUDY; CYTOKINE RELEASE; GRANULOCYTE; HUMAN; HUMAN CELL; IMMUNOSTIMULATION; MONOCYTE; MOUSE; NATURAL KILLER CELL; NONHUMAN; PERIPHERAL BLOOD MONONUCLEAR CELL; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN SECRETION; PROTEIN STABILITY; RNA VIRUS; VIRUS NUCLEOCAPSID;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; ANTIGENS, DIFFERENTIATION; CYTOKINES; DENDRITIC CELLS; ENZYME-LINKED IMMUNOSORBENT ASSAY; GRANULOCYTES; HUMANS; LEUKOCYTES, MONONUCLEAR; MEMBRANE GLYCOPROTEINS; MICE; MYELOID DIFFERENTIATION FACTOR 88; NEUTROPHIL ACTIVATION; PROTAMINES; RECEPTORS, CELL SURFACE; RECEPTORS, IMMUNOLOGIC; RNA, MESSENGER; TOLL-LIKE RECEPTOR 7; TOLL-LIKE RECEPTOR 8; TOLL-LIKE RECEPTORS;

EID: 21044440406     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200425656     Document Type: Article

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