Innate immune suppression enables frequent transfection with RNA encoding reprogramming proteins

PLoS ONE

Volumn 5, Issue 7, 2010, Pages

  Angel, Matthew ^a   Yanik, Mehmet Fatih ^a,b  

^a Department of Electrical Engineering and Computer Science   (United States)

^b USA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA INTERFERON; INITIATION FACTOR 2ALPHA; KRUPPEL LIKE FACTOR 4; OCTAMER TRANSCRIPTION FACTOR 4; PROTEIN UTF1; RNA; SMALL INTERFERING RNA; STAT2 PROTEIN; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR SOX2; UNCLASSIFIED DRUG; KRUPPEL LIKE FACTOR; NUCLEAR PROTEIN; POU5F1 PROTEIN, HUMAN; PROTEIN SERINE THREONINE KINASE; STAT2 PROTEIN, MOUSE; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR SOX; UTF1 PROTEIN, HUMAN;

ARTICLE; DESENSITIZATION; FIBROBLAST; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; INNATE IMMUNITY; PROTEIN EXPRESSION; ANIMAL; CELL CULTURE; CELL LINE; GENETICS; IMMUNOHISTOCHEMISTRY; METABOLISM; METHODOLOGY; MOUSE; PHYSIOLOGY; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

RNA VIRUSES;

ANIMALS; BLOTTING, WESTERN; CELL LINE; CELLS, CULTURED; FIBROBLASTS; IMMUNITY, INNATE; IMMUNOHISTOCHEMISTRY; INTERFERON-BETA; KRUPPEL-LIKE TRANSCRIPTION FACTORS; MICE; NUCLEAR PROTEINS; OCTAMER TRANSCRIPTION FACTOR-3; PROTEIN-SERINE-THREONINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, SMALL INTERFERING; SOXB1 TRANSCRIPTION FACTORS; STAT2 TRANSCRIPTION FACTOR; TRANS-ACTIVATORS; TRANSFECTION;

EID: 77955352428     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0011756     Document Type: Article

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