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Volumn 366, Issue 1579, 2011, Pages 2748-2755

Innate immunity and adjuvants

Author keywords

Dendritic cell; Influenza virus; Interferon; Signalling pathway; Toll like receptor

Indexed keywords

ADAPTATION; ALLERGY; ANTIGEN; CANCER; CYTOPLASM; DISEASE TREATMENT; HOST-PATHOGEN INTERACTION; IMMUNITY; PARADIGM SHIFT; PATHOGEN; PATHOGENICITY; VIRAL DISEASE; VIRUS;

EID: 80052464906     PISSN: 09628436     EISSN: 14712970     Source Type: Journal    
DOI: 10.1098/rstb.2011.0106     Document Type: Article
Times cited : (130)

References (36)
  • 1
    • 0030595339 scopus 로고    scopus 로고
    • The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults
    • 10.1016/S0092-8674(00)80172-5
    • Lemaitre, B., Nicolas, E., Michaut, L., Reichhart, J. M. & Hoffmann, J. A. 1996 The dorsoventral regulatory gene cassette spätzle/Toll/cactus controls the potent antifungal response in Drosophila adults. Cell 86, 973-983. (doi:10.1016/S0092-8674(00)80172-5)
    • (1996) Cell , vol.86 , pp. 973-983
    • Lemaitre, B.1    Nicolas, E.2    Michaut, L.3    Reichhart, J.M.4    Hoffmann, J.A.5
  • 2
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • 10.1016/j.cell.2006.02.015
    • Akira, S., Uematsu, S. & Takeuchi, O. 2006 Pathogen recognition and innate immunity. Cell 124, 783-801. (doi:10.1016/j.cell.2006.02.015)
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 3
    • 3142654210 scopus 로고    scopus 로고
    • Inferences, questions and possibilities in Toll-like receptor signalling
    • 10.1038/nature02761
    • Beutler, B. 2004 Inferences, questions and possibilities in Toll-like receptor signalling. Nature 430, 257-263. (doi:10.1038/nature02761)
    • (2004) Nature , vol.430 , pp. 257-263
    • Beutler, B.1
  • 4
    • 35349016235 scopus 로고    scopus 로고
    • Recognition of microorganisms and activation of the immune response
    • 10.1038/nature06246
    • Medzhitov, R. 2007 Recognition of microorganisms and activation of the immune response. Nature 449, 819-826. (doi:10.1038/nature06246)
    • (2007) Nature , vol.449 , pp. 819-826
    • Medzhitov, R.1
  • 5
    • 0032509295 scopus 로고
    • Defective LPS signaling in C3H/ HeJ and C57BL/10ScCr mice: Mutations in Tlr4 gene
    • 10.1126/science.282. 5396.2085
    • Poltorak, X. et al. 1988 Defective LPS signaling in C3H/ HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 282, 2085-2088. (doi:10.1126/science.282. 5396.2085)
    • (1988) Science , vol.282 , pp. 2085-2088
    • Poltorak, X.1
  • 6
    • 0033120081 scopus 로고    scopus 로고
    • Cutting Edge: TLR4-deficient mice are hyporesponsive to LPS: Evidence for TLR4 as the Lps gene product
    • Hoshino, K., Takeuchi, O., Kawai, T., Sanjo, H., Ogawa, T., Takeda, Y., Takeda, K. & Akira, S. 1999 Cutting Edge: TLR4-deficient mice are hyporesponsive to LPS: evidence for TLR4 as the Lps gene product. J. Immunol. 162, 3749-3752.
    • (1999) J. Immunol , vol.162 , pp. 3749-3752
    • Hoshino, K.1    Takeuchi, O.2    Kawai, T.3    Sanjo, H.4    Ogawa, T.5    Takeda, Y.6    Takeda, K.7    Akira, S.8
  • 7
    • 0033532629 scopus 로고    scopus 로고
    • MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4
    • 10.1084/jem.189.11.1777
    • Shimazu, R., Akash, i.S., Ogata, H., Nagai, Y., Fukudome, K., Miyake, K. & Kimot, M. 1999 MD-2, a molecule that confers lipopolysaccharide responsiveness on Toll-like receptor 4. J. Exp. Med. 189, 1777-1782. (doi:10.1084/jem.189.11.1777)
    • (1999) J. Exp. Med , vol.189 , pp. 1777-1782
    • Shimazu, R.1    Akash, I.S.2    Ogata, H.3    Nagai, Y.4    Fukudome, K.5    Miyake, K.6    Kimot, M.7
  • 8
    • 0033213590 scopus 로고    scopus 로고
    • Differential roles of Toll-like receptor (TLR) 2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components
    • 10. 1016/S1074-7613(00)80119-3
    • Takeuchi, O., Hoshino, K., Kawai, T., Sanjo, H., Takada, H., Ogawa, T., Takeda, K. & Akira, S. 1999 Differential roles of Toll-like receptor (TLR) 2 and TLR4 in recognition of Gram-negative and Gram-positive bacterial cell wall components. Immunity 11, 443-451. (doi:10. 1016/S1074-7613(00)80119-3)
    • (1999) Immunity , vol.11 , pp. 443-451
    • Takeuchi, O.1    Hoshino, K.2    Kawai, T.3    Sanjo, H.4    Takada, H.5    Ogawa, T.6    Takeda, K.7    Akira, S.8
  • 9
    • 0034650420 scopus 로고    scopus 로고
    • Cutting Edge: Preferentially the R-stereoisomer of the mycoplasmal lipopeptide MALP-2 activates immune cells through a TLR-2 and MyD88-dependent signaling pathway
    • Takeuchi, O., Grotel, K., Kaufmann, A., Kawai, T., Hoshino, K., Morrl, M., Muhlradt, P. F. & Akira, S. 2000 Cutting Edge: preferentially the R-stereoisomer of the mycoplasmal lipopeptide MALP-2 activates immune cells through a TLR-2 and MyD88-dependent signaling pathway. J. Immunol 164, 554-557.
    • (2000) J. Immunol , vol.164 , pp. 554-557
    • Takeuchi, O.1    Grotel, K.2    Kaufmann, A.3    Kawai, T.4    Hoshino, K.5    Morrl, M.6    Muhlradt, P.F.7    Akira, S.8
  • 11
    • 0035953543 scopus 로고    scopus 로고
    • The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
    • 10.1038/35074106
    • Hayashi, F. et al. 2001 The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 410, 1099-1103. (doi:10.1038/35074106)
    • (2001) Nature , vol.410 , pp. 1099-1103
    • Hayashi, F.1
  • 12
    • 33746161021 scopus 로고    scopus 로고
    • Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c(+) lamina propria cells
    • 10. 1038/ni1362
    • Uematsu, S. et al. 2006 Detection of pathogenic intestinal bacteria by Toll-like receptor 5 on intestinal CD11c(+) lamina propria cells. Nat. Immunol. 7, 868-874. (doi:10. 1038/ni1362)
    • (2006) Nat. Immunol , vol.7 , pp. 868-874
    • Uematsu, S.1
  • 13
    • 0034619794 scopus 로고    scopus 로고
    • A Toll-like receptor recognizes bacterial DNA
    • 10.1038/ 35047123
    • Hemmi, H. et al. 2000 A Toll-like receptor recognizes bacterial DNA. Nature 408, 740-745. (doi:10.1038/ 35047123)
    • (2000) Nature , vol.408 , pp. 740-745
    • Hemmi, H.1
  • 14
    • 0036008014 scopus 로고    scopus 로고
    • Small anti-viral compounds activate immune cells via the TLR7-MyD88-dependent signaling pathway
    • 10. 1038/ni758
    • Hemmi, H. et al. 2002 Small anti-viral compounds activate immune cells via the TLR7-MyD88-dependent signaling pathway. Nat. Immunol. 3, 196-200. (doi:10. 1038/ni758)
    • (2002) Nat. Immunol , vol.3 , pp. 196-200
    • Hemmi, H.1
  • 15
    • 1542317578 scopus 로고    scopus 로고
    • Species-specific recognition of single-stranded RNA via toll-like receptors 7 and 8
    • 10.1126/science.1093620
    • Heil, F., Hemmi, H., Hochrein, H., Ampenberger, F., Kirschning, C., Akira, S., Li, G., Wagner, H. & Baer, S. 2004 Species-specific recognition of single-stranded RNA via toll-like receptors 7 and 8. Science 505, 1526-1529. (doi:10.1126/science.1093620)
    • (2004) Science , vol.505 , pp. 1526-1529
    • Heil, F.1    Hemmi, H.2    Hochrein, H.3    Ampenberger, F.4    Kirschning, C.5    Akira, S.6    Li, G.7    Wagner, H.8    Baer, S.9
  • 16
    • 1542317550 scopus 로고    scopus 로고
    • Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
    • 10.1126/science.1093616
    • Dinebold, S. S., Kaisho, T., Hemmi, H., Akira, S. & Reise Sousa, C. 2004 Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 505, 1529-1531. (doi:10.1126/science.1093616)
    • (2004) Science , vol.505 , pp. 1529-1531
    • Dinebold, S.S.1    Kaisho, T.2    Hemmi, H.3    Akira, S.4    Reise Sousa, C.5
  • 17
    • 0035909372 scopus 로고    scopus 로고
    • Recognition of double-stranded RNA and activation of NF-kB by Toll-like receptor 3
    • 10.1038/35099560
    • Alexopoulou, L., Holt, A. C., Medzhitov, R. & Flavell, R. A. 2001 Recognition of double-stranded RNA and activation of NF-kB by Toll-like receptor 3. Nature 413, 732-738. (doi:10.1038/35099560)
    • (2001) Nature , vol.413 , pp. 732-738
    • Alexopoulou, L.1    Holt, A.C.2    Medzhitov, R.3    Flavell, R.A.4
  • 18
    • 0033166472 scopus 로고    scopus 로고
    • Unresponsiveness of MyD88-deficient mice to endotoxin
    • 10.1016/ S1074-7613(00)80086-2
    • Kawai, T., Adachi, O., Ogawa, T., Takeda, K. & Akira, S. 1999 Unresponsiveness of MyD88-deficient mice to endotoxin. Immunity 11, 115-122. (doi:10.1016/ S1074-7613(00)80086-2)
    • (1999) Immunity , vol.11 , pp. 115-122
    • Kawai, T.1    Adachi, O.2    Ogawa, T.3    Takeda, K.4    Akira, S.5
  • 19
    • 51349158231 scopus 로고    scopus 로고
    • Signalling adaptors used by Toll-like receptors: An update
    • 10.1016/j.cyto.2008.07.010
    • Kenny, E. F. & O'Neill, L. A. 2008 Signalling adaptors used by Toll-like receptors: an update. Cytokine 43, 342-349. (doi:10.1016/j.cyto.2008.07.010)
    • (2008) Cytokine , vol.43 , pp. 342-349
    • Kenny, E.F.1    O'Neill, L.A.2
  • 20
    • 77951260924 scopus 로고    scopus 로고
    • The role of pattern-recognition receptors in innate immunity: Update on Toll-like receptors
    • 10.1038/ni. 1863
    • Kawai, T. & Akira, S. 2010 The role of pattern-recognition receptors in innate immunity: update on Toll-like receptors. Nat. Immunol. 11, 373-384. (doi:10.1038/ni. 1863)
    • (2010) Nat. Immunol , vol.11 , pp. 373-384
    • Kawai, T.1    Akira, S.2
  • 21
    • 0043176281 scopus 로고    scopus 로고
    • Role of adaptor TRIF in the MyD88-independent Toll-like receptor signaling pathway
    • 10.1126/science.1087262
    • Yamamoto, M. et al. 2003 Role of adaptor TRIF in the MyD88-independent Toll-like receptor signaling pathway. Science 301, 640-643. (doi:10.1126/science.1087262)
    • (2003) Science , vol.301 , pp. 640-643
    • Yamamoto, M.1
  • 22
    • 5444274514 scopus 로고    scopus 로고
    • Interferon-a induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6
    • 10.1038/ni1118
    • Kawai, T. et al. 2004 Interferon-a induction through Toll-like receptors involves a direct interaction of IRF7 with MyD88 and TRAF6. Nat. Immunol. 5, 1061-1068. (doi:10.1038/ni1118)
    • (2004) Nat. Immunol , vol.5 , pp. 1061-1068
    • Kawai, T.1
  • 23
    • 58049217490 scopus 로고    scopus 로고
    • RNA recognition and signal transduction by RIG-I-like receptors
    • 10.1111/j.1600-065X.2008.00727.x
    • Yoneyama, M. & Fujita, T. 2009 RNA recognition and signal transduction by RIG-I-like receptors. Immunol. Rev. 227, 54-65. (doi:10.1111/j.1600-065X.2008.00727.x)
    • (2009) Immunol. Rev , vol.227 , pp. 54-65
    • Yoneyama, M.1    Fujita, T.2
  • 24
    • 58049202272 scopus 로고    scopus 로고
    • Innate immunity to virus infection
    • 10.1111/j. 1600-065X.2008.00737.x
    • Takeuchi, O. & Akira, S. 2009 Innate immunity to virus infection. Immunol. Rev. 227, 75-86. (doi:10.1111/j. 1600-065X.2008.00737.x)
    • (2009) Immunol Rev , vol.227 , pp. 75-86
    • Takeuchi, O.1    Akira, S.2
  • 25
    • 3242813113 scopus 로고    scopus 로고
    • 2004 The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses
    • 10. 1038/ni1087
    • Yoneyama, M., Kikuchi, M., Matsukawa, T., Shinobu, N., Imaizaumi, T., Miyagishi, M., Taira, K., Akira, S. & Fujita, T. 2004 The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses. Nat. Immunol. 5, 730-737. (doi:10. 1038/ni1087)
    • Nat. Immunol , vol.5 , pp. 730-737
    • Yoneyama, M.1    Kikuchi, M.2    Matsukawa, T.3    Shinobu, N.4    Imaizaumi, T.5    Miyagishi, M.6    Taira, K.7    Akira, S.8    Fujita, T.9
  • 26
    • 22544455673 scopus 로고    scopus 로고
    • Cell type-specific involvement of RIG-I in antiviral response
    • 10.1016/j.immuni.2005.04.010
    • Kato, H. et al. 2005 Cell type-specific involvement of RIG-I in antiviral response. Immunity 23, 19-28. (doi:10.1016/j.immuni.2005.04.010)
    • (2005) Immunity , vol.23 , pp. 19-28
    • Kato, H.1
  • 28
    • 24144461689 scopus 로고    scopus 로고
    • Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NFkB and IRF 3
    • 10.1016/j.cell. 2005.08.012
    • Seth, R. B., Sun, L., Ea, C. K. & Chen, Z. J. 2005 Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NFkB and IRF 3. Cell 122, 669-682. (doi:10.1016/j.cell. 2005.08.012)
    • (2005) Cell , vol.122 , pp. 669-682
    • Seth, R.B.1    Sun, L.2    Ea, C.K.3    Chen, Z.J.4
  • 29
    • 33646342149 scopus 로고    scopus 로고
    • Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
    • 10.1038/nature04734
    • Kato, H. et al. 2006 Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 441, 101-105. (doi:10.1038/nature04734)
    • (2006) Nature , vol.441 , pp. 101-105
    • Kato, H.1
  • 30
    • 46949097299 scopus 로고    scopus 로고
    • Length-dependent recognition of double-stranded ribonucleic acids by retinoic acidinducible gene-I and melanoma differentiation-associated gene 5
    • 10. 1084/jem.20080091
    • Kato, H. et al. 2008 Length-dependent recognition of double-stranded ribonucleic acids by retinoic acidinducible gene-I and melanoma differentiation-associated gene 5. J. Exp. Med. 205, 1601-1610. (doi:10. 1084/jem.20080091)
    • (2008) J. Exp. Med , vol.205 , pp. 1601-1610
    • Kato, H.1
  • 31
    • 53349178089 scopus 로고    scopus 로고
    • STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
    • 10. 1038/nature07317
    • Ishikawa, H. & Barber, G. N. 2008 STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling. Nature 455, 674-678. (doi:10. 1038/nature07317)
    • (2008) Nature , vol.455 , pp. 674-678
    • Ishikawa, H.1    Barber, G.N.2
  • 32
    • 17644366913 scopus 로고    scopus 로고
    • NOD-LRR proteins: Role in host-microbial interactions and inflammatory disease
    • 10.1146/annurev.biochem.74. 082803.133347
    • Inohara, N., Chamaillard, M., McDonald, C. & Nuñez, G. 2005 NOD-LRR proteins: role in host-microbial interactions and inflammatory disease. Annu. Rev. Biochem. 74, 355-383. (doi:10.1146/annurev.biochem.74. 082803.133347)
    • (2005) Annu Rev. Biochem , vol.74 , pp. 355-383
    • Inohara, N.1    Chamaillard, M.2    McDonald, C.3    Nuñez, G.4
  • 33
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • 10.1016/j.cell.2010.01.040
    • Schroder, K. & Tschopp, J. 2010 The inflammasomes. Cell 140, 821-832.(doi:10.1016/j.cell.2010.01.040)
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 34
    • 70349213245 scopus 로고    scopus 로고
    • The Dectin-2 family of C-type lectins in immunity and homeostasis
    • 10.1016/j.cyto.2009.07.010
    • Graham, L. M. & Brown, G. D. 2009 The Dectin-2 family of C-type lectins in immunity and homeostasis. Cytokine 48, 148-155. (doi:10.1016/j.cyto.2009.07.010)
    • (2009) Cytokine , vol.48 , pp. 148-155
    • Graham, L.M.1    Brown, G.D.2
  • 35
    • 38949117752 scopus 로고    scopus 로고
    • Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination
    • Koyama, S., Ishii, K. J., Kumar, H., Tanimoto, T., Coban, C., Uematsu, S., Kawai, T. & Akira, S. 2007 Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination. J. Immunol. 179, 4711-4720.
    • (2007) J. Immunol , vol.179 , pp. 4711-4720
    • Koyama, S.1    Ishii, K.J.2    Kumar, H.3    Tanimoto, T.4    Coban, C.5    Uematsu, S.6    Kawai, T.7    Akira, S.8
  • 36
    • 77952982038 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypes
    • 25ra24., 10.1126/scitranslmed. 3000759
    • Koyama, S. et al. 2010 Plasmacytoid dendritic cells delineate immunogenicity of influenza vaccine subtypes. Sci. Transl. Med. 2, 25ra24. (doi:10.1126/scitranslmed. 3000759)
    • (2010) Sci. Transl. Med , vol.2
    • Koyama, S.1


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