Metabolic regulation of oxygen and redox homeostasis by p53: Lessons from evolutionary biology?

Free Radical Biology and Medicine

Volumn 53, Issue 6, 2012, Pages 1279-1285

  Zhuang, Jie ^a   Ma, Wenzhe ^a   Lago, Cory U ^a   Hwang, Paul M ^a  

^a NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

Author keywords

Altitude; Antioxidant; Cancer; Free radicals; Metabolism; Mitochondria; Oxidative stress; Oxygen; p53; Redox

Indexed keywords

APURINIC ENDONUCLEASE; GLUTATHIONE PEROXIDASE 1; GUANIDINOACETATE METHYLTRANSFERASE; HYPOXIA INDUCIBLE FACTOR; MANGANESE SUPEROXIDE DISMUTASE; OXYGEN; PROTEIN; PROTEIN P53; REACTIVE OXYGEN METABOLITE; REDOX EFFECTOR FACTOR 1; TRANSCRIPTION FACTOR NRF2; UNCLASSIFIED DRUG;

CARCINOGENESIS; CELL ACTIVITY; CELL METABOLISM; DNA DAMAGE; GENE SEQUENCE; GENOMIC INSTABILITY; MITOCHONDRION; OXIDATION REDUCTION REACTION; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN STABILITY; PROTEIN STRUCTURE; REVIEW; UBIQUITINATION;

ANIMALS; BIOLOGICAL EVOLUTION; CELL TRANSFORMATION, NEOPLASTIC; GENOMIC INSTABILITY; HOMEOSTASIS; HUMANS; MUTATION; OXIDATION-REDUCTION; OXIDATIVE STRESS; OXYGEN; TUMOR SUPPRESSOR PROTEIN P53;

EID: 84865301808     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2012.07.026     Document Type: Review

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