Regulation of monocarboxylate transporter MCT1 expression by p53 mediates inward and outward lactate fluxes in tumors

Cancer Research

Volumn 72, Issue 4, 2012, Pages 939-948

  Boidot, Romain ^a,b   Veǵran, Fred́eŕique ^a,b   Meulle, Aline ^a   Le Breton, Aude ^a   Dessy, Chantal ^a   Sonveaux, Pierre ^a   Lizard Nacol, Sarab ^b   Feron, Olivier ^a  

^a UNIVERSITÉ CATHOLIQUE DE LOUVAIN   (Belgium)

^b CENTRE GEORGES FRANÇOIS LECLERC   (France)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; LACTIC ACID; MONOCARBOXYLATE TRANSPORTER 1; PROTEIN P53;

ARTICLE; BREAST CANCER; CELL HYPOXIA; CELL PROLIFERATION; CONTROLLED STUDY; GENE; GENE EXPRESSION; GLYCOLYSIS; HUMAN; HUMAN CELL; HUMAN TISSUE; IN VITRO STUDY; LOSS OF FUNCTION MUTATION; MCT1 GENE; MITOCHONDRIAL RESPIRATION; PRIORITY JOURNAL; PROGNOSIS; PROMOTER REGION; PROTEIN EXPRESSION; TUMOR SUPPRESSOR GENE; UPREGULATION;

BIOLOGICAL TRANSPORT; CELL HYPOXIA; CELL LINE, TUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE KNOCKDOWN TECHNIQUES; GENES, P53; GLYCOLYSIS; HUMANS; LACTIC ACID; MONOCARBOXYLIC ACID TRANSPORTERS; NEOPLASMS; PROTEIN-SERINE-THREONINE KINASES; RNA, MESSENGER; SYMPORTERS;

EID: 84857222449     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-11-2474     Document Type: Article

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