Prevention of hypoxia by myoglobin expression in human tumor cells promotes differentiation and inhibits metastasis

Journal of Clinical Investigation

Volumn 119, Issue 4, 2009, Pages 865-875

  Galluzzo, Maria ^a   Pennacchietti, Selma ^a   Rosano, Stefania ^a   Comoglio, Paolo M ^a   Michieli, Paolo ^a  

^a UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; MYOGLOBIN; OXYGEN; HIF1A PROTEIN, HUMAN; PRIMER DNA; RECOMBINANT PROTEIN;

ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; BINDING AFFINITY; CANCER INHIBITION; CELL DENSITY; CELL DIFFERENTIATION; CELL EXPANSION; CONTROLLED STUDY; FEMALE; GROWTH INHIBITION; HUMAN; HUMAN CELL; HYPOXIA; IN VITRO STUDY; LUNG CARCINOMA; METASTASIS; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; OXYGEN TRANSPORT; OXYGENATION; POINT MUTATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STORAGE; TUMOR; TUMOR CELL; TUMOR ENGRAFTMENT; TUMOR GROWTH; XENOGRAFT; XENOTRANSPLANTATION; AMINO ACID SEQUENCE; ANIMAL; CANCER TRANSPLANTATION; CELL DEATH; CELL HYPOXIA; CELL PROLIFERATION; GENE EXPRESSION; GENETIC TRANSDUCTION; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; NEOPLASM; NEOVASCULARIZATION (PATHOLOGY); NUDE MOUSE; PATHOLOGY; SEQUENCE HOMOLOGY; TUMOR CELL LINE; VASCULARIZATION;

AMINO ACID SEQUENCE; ANIMALS; BASE SEQUENCE; CELL DEATH; CELL DIFFERENTIATION; CELL HYPOXIA; CELL LINE, TUMOR; CELL PROLIFERATION; DNA PRIMERS; FEMALE; GENE EXPRESSION; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, NUDE; MOLECULAR SEQUENCE DATA; MUTATION; MYOGLOBIN; NEOPLASM METASTASIS; NEOPLASM TRANSPLANTATION; NEOPLASMS; NEOVASCULARIZATION, PATHOLOGIC; OXYGEN; RECOMBINANT PROTEINS; SEQUENCE HOMOLOGY, AMINO ACID; TRANSDUCTION, GENETIC; TRANSPLANTATION, HETEROLOGOUS;

EID: 65249095487     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI36579     Document Type: Article

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