Mitochondrial genome instability and ROS enhance intestinal tumorigenesis in APC Min/+ mice

American Journal of Pathology

Volumn 180, Issue 1, 2012, Pages 24-31

  Woo, Dong Kyun ^a,b   Green, Paula D ^c   Santos, Janine H ^c   D'Souza, Anthony D ^a   Walther, Zenta ^a   Martin, W David ^d   Christian, Brooke E ^a   Chandel, Navdeep S ^e   Shadel, Gerald S ^a  

^a YALE UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Gyeongsang National University   (South Korea)

^c RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^d EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^e NORTHWESTERN UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA CATENIN; CATALASE; MITOCHONDRIAL DNA; MITOCHONDRIAL TRANSCRIPTION FACTOR A; REACTIVE OXYGEN METABOLITE; WNT PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; APOPTOSIS; ARTICLE; CANCER CELL; CARCINOGENESIS; COLON POLYPOSIS; CONTROLLED STUDY; DNA DAMAGE; EMBRYO; FEMALE; GENE MUTATION; GENOMIC INSTABILITY; INTESTINE CANCER; MALE; MITOCHONDRIAL GENOME; MOUSE; NONHUMAN; OXIDATIVE PHOSPHORYLATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TUMOR GROWTH;

ADENOMATOUS POLYPOSIS COLI; ANIMALS; CELL TRANSFORMATION, NEOPLASTIC; DNA DAMAGE; DNA, MITOCHONDRIAL; DNA-BINDING PROTEINS; GENOME, MITOCHONDRIAL; GENOMIC INSTABILITY; HIGH MOBILITY GROUP PROTEINS; MICE; MICE, KNOCKOUT; MITOCHONDRIAL DISEASES; REACTIVE OXYGEN SPECIES;

EID: 83455228665     PISSN: 00029440     EISSN: 15252191     Source Type: Journal    
DOI: 10.1016/j.ajpath.2011.10.003     Document Type: Article

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