Ferredoxin reductase affects p53-dependent, 5-fluorouracil-induced apoptosis in colorectal cancer cells

Nature Medicine

Volumn 7, Issue 10, 2001, Pages 1111-1117

  Hwang, Paul M ^a,b,c   Bunz, Fred ^b   Yu, Jian ^b   Rago, Carlo ^a   Chan, Timothy A ^b   Murphy, Michael P ^d   Kelso, Geoffry F ^e   Smith, Robin A J ^e   Kinzler, Kenneth W ^b   Vogelstein, Bert ^a,b  

^a JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY   (United States)

^c NATIONAL HEART LUNG AND BLOOD INSTITUTE   (United States)

^d WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^e UNIVERSITY OF OTAGO   (New Zealand)

Author keywords

[No Author keywords available]

Indexed keywords

FERREDOXIN REDUCTASE; FLUOROURACIL; GENE PRODUCT; PROTEIN P53; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL; CELL GROWTH; CELL VIABILITY; COLORECTAL CANCER; CONTROLLED STUDY; DNA FLANKING REGION; DRUG EFFECT; DRUG MECHANISM; ENZYME MECHANISM; GENE EXPRESSION; GENE FUNCTION; GENE INDUCTION; GENE OVEREXPRESSION; GENETIC CODE; HUMAN; HUMAN CELL; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

ANTIMETABOLITES, ANTINEOPLASTIC; APOPTOSIS; CELL DIVISION; COLORECTAL NEOPLASMS; FERREDOXIN-NADP REDUCTASE; FLOW CYTOMETRY; FLUOROURACIL; GENE EXPRESSION; GENE TARGETING; HUMANS; OXIDATIVE STRESS; RECOMBINATION, GENETIC; TUMOR CELLS, CULTURED; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0034775927     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm1001-1111     Document Type: Article

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