메뉴 건너뛰기




Volumn 63, Issue 5, 2003, Pages 980-986

Wild-type p53 regulates human ribonucleotide reductase by protein-protein interaction with p53R2 as well as hRRM2 subunits

Author keywords

[No Author keywords available]

Indexed keywords

DEOXYRIBONUCLEOTIDE; PROTEIN P53; PROTEIN SUBUNIT; RIBONUCLEOTIDE; RIBONUCLEOTIDE REDUCTASE;

EID: 0037374051     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (109)

References (47)
  • 1
    • 0025602528 scopus 로고
    • Regulation and drug resistance mechanisms of mammalian ribonucleotide reductase, and the significance to DNA synthesis
    • Wright, J. A., Chan, A. K., Choy, B. K., Hurta, R. A., and McClarty, G. A. Regulation and drug resistance mechanisms of mammalian ribonucleotide reductase, and the significance to DNA synthesis. Biochem. Cell Biol., 68: 1364-1371, 1990.
    • (1990) Biochem. Cell Biol. , vol.68 , pp. 1364-1371
    • Wright, J.A.1    Chan, A.K.2    Choy, B.K.3    Hurta, R.A.4    McClarty, G.A.5
  • 2
    • 0026713701 scopus 로고
    • Alterations in the activity and regulation of mammalian ribonucleotide reductase by chlorambucil, a DNA damaging agent
    • Hurta, R. A., and Wright, J. A. Alterations in the activity and regulation of mammalian ribonucleotide reductase by chlorambucil, a DNA damaging agent. J. Biol. Chem., 267: 7066-7071, 1992.
    • (1992) J. Biol. Chem. , vol.267 , pp. 7066-7071
    • Hurta, R.A.1    Wright, J.A.2
  • 5
    • 0035798630 scopus 로고    scopus 로고
    • Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells
    • Guittet, O., Hakansson, P., Voevodskaya, N., Fridd, S., Graslund, A., Arakawa, H., Nakamura, Y., and Thelander, L. Mammalian p53R2 protein forms an active ribonucleotide reductase in vitro with the R1 protein, which is expressed both in resting cells in response to DNA damage and in proliferating cells. J. Biol. Chem., 276: 40647-40651, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 40647-40651
    • Guittet, O.1    Hakansson, P.2    Voevodskaya, N.3    Fridd, S.4    Graslund, A.5    Arakawa, H.6    Nakamura, Y.7    Thelander, L.8
  • 6
    • 0032988122 scopus 로고    scopus 로고
    • Introduction: p53 - The first twenty years
    • Oren. M., and Rotter, V. Introduction: p53 - the first twenty years. Cell Mol. Life Sci., 55: 9-11, 1999.
    • (1999) Cell Mol. Life Sci. , vol.55 , pp. 9-11
    • Oren, M.1    Rotter, V.2
  • 7
    • 0033552638 scopus 로고    scopus 로고
    • Twenty years of p53 research: Structural and functional aspects of the p53 protein
    • May, P., and May, E. Twenty years of p53 research: structural and functional aspects of the p53 protein. Oncogene, 18: 7621-7636, 1999.
    • (1999) Oncogene , vol.18 , pp. 7621-7636
    • May, P.1    May, E.2
  • 8
    • 0030941458 scopus 로고    scopus 로고
    • p53, the cellular gatekeeper for growth and division
    • Levine, A. J. p53, the cellular gatekeeper for growth and division. Cell, 88: 323-331, 1997.
    • (1997) Cell , vol.88 , pp. 323-331
    • Levine, A.J.1
  • 9
    • 0029670589 scopus 로고    scopus 로고
    • p53 in signaling checkpoint arrest or apoptosis
    • Bates, S., and Vousden, K. H. p53 in signaling checkpoint arrest or apoptosis. Curr. Opin. Genet. Dev., 6: 12-18, 1996.
    • (1996) Curr. Opin. Genet. Dev. , vol.6 , pp. 12-18
    • Bates, S.1    Vousden, K.H.2
  • 10
    • 0031987277 scopus 로고    scopus 로고
    • Regulation of p53 downstream genes
    • El-Deiry, W. S. Regulation of p53 downstream genes. Semin. Cancer Biol., 8: 345-357, 1998.
    • (1998) Semin. Cancer Biol. , vol.8 , pp. 345-357
    • El-Deiry, W.S.1
  • 11
    • 0037122893 scopus 로고    scopus 로고
    • The interaction of p53 with the neuclear matrix is mediated by F-actin and modulated by DNA damage
    • Okorokov, A. L., Rubbi, C. P., Metcalfe, S., and Milner, J. The interaction of p53 with the neuclear matrix is mediated by F-actin and modulated by DNA damage. Oncogene, 21: 356-367. 2002.
    • (2002) Oncogene , vol.21 , pp. 356-367
    • Okorokov, A.L.1    Rubbi, C.P.2    Metcalfe, S.3    Milner, J.4
  • 12
    • 0035893389 scopus 로고    scopus 로고
    • Interaction of p53 and DNA-PK in response to nucleoside analogues: Potential role as a sensor complex for DNA damage
    • Achanta, G., Pelicano, H., Feng, L., Plunkett, W., and Huang, P. Interaction of p53 and DNA-PK in response to nucleoside analogues: potential role as a sensor complex for DNA damage. Cancer Res., 61: 8723-8729, 2001.
    • (2001) Cancer Res. , vol.61 , pp. 8723-8729
    • Achanta, G.1    Pelicano, H.2    Feng, L.3    Plunkett, W.4    Huang, P.5
  • 13
    • 0034625375 scopus 로고    scopus 로고
    • Controlled protein degradation regulates ribonucleotide reductase activity in proliferating mammalian cells during the normal cell cycle and in response to DNA damage and replication blocks
    • Chabes, A., and Thelander, L. Controlled protein degradation regulates ribonucleotide reductase activity in proliferating mammalian cells during the normal cell cycle and in response to DNA damage and replication blocks. J. Biol. Chem., 275: 17747-17753, 2000.
    • (2000) J. Biol. Chem. , vol.275 , pp. 17747-17753
    • Chabes, A.1    Thelander, L.2
  • 14
    • 85047680162 scopus 로고    scopus 로고
    • p53 accumulates but is functionally impaired when DNA synthesis is blocked
    • Gottifredi, V., Shieh, S., Taya, Y., and Prives, C. p53 accumulates but is functionally impaired when DNA synthesis is blocked. Proc. Natl. Acad. Sci. USA, 98: 1036-1041, 2001.
    • (2001) Proc. Natl. Acad. Sci. USA , vol.98 , pp. 1036-1041
    • Gottifredi, V.1    Shieh, S.2    Taya, Y.3    Prives, C.4
  • 15
    • 0027486697 scopus 로고
    • Replitase: A complex integrating dNTP synthesis and DNA replication
    • Reddy, G. P., and Fager, R. S. Replitase: a complex integrating dNTP synthesis and DNA replication. Crit. Rev. Eukaryot. Gene Expr., 3: 255-277, 1993.
    • (1993) Crit. Rev. Eukaryot. Gene Expr. , vol.3 , pp. 255-277
    • Reddy, G.P.1    Fager, R.S.2
  • 16
    • 0022610664 scopus 로고
    • Eukaryotic DNA metabolism. Are deoxyribonucleotides channeled to replication sites?
    • Mathews, C. K., and Slabaugh, M. B. Eukaryotic DNA metabolism. Are deoxyribonucleotides channeled to replication sites? Exp. Cell Res., 162: 285-295, 1986.
    • (1986) Exp. Cell Res. , vol.162 , pp. 285-295
    • Mathews, C.K.1    Slabaugh, M.B.2
  • 17
    • 0021765989 scopus 로고
    • Studies directed toward testing the "channeling" hypothesis-ribonucleotides - DNA in leukemia L1210 cells
    • Chiba, P., Bacon, P. E., and Cory, J. G. Studies directed toward testing the "channeling" hypothesis-ribonucleotides - DNA in leukemia L1210 cells. Biochem. Biophys. Res. Commun., 123: 656-662, 1984.
    • (1984) Biochem. Biophys. Res. Commun. , vol.123 , pp. 656-662
    • Chiba, P.1    Bacon, P.E.2    Cory, J.G.3
  • 18
    • 0019025846 scopus 로고
    • Multienzyme complex for metabolic channeling in mammalian DNA replication
    • Prem veer Reddy, G., and Pardee, A. B. Multienzyme complex for metabolic channeling in mammalian DNA replication. Proc. Natl. Acad. Sci. USA, 77: 3312-3316, 1980.
    • (1980) Proc. Natl. Acad. Sci. USA , vol.77 , pp. 3312-3316
    • Prem veer Reddy, G.1    Pardee, A.B.2
  • 19
    • 0021417356 scopus 로고
    • Localization of ribonucleotide reductase in mammalian cells
    • Engstrom, Y., Rozell, B., Hansson, H. A., Stemme, S., and Thelander, L. Localization of ribonucleotide reductase in mammalian cells. EMBO. J., 3: 863-867, 1984.
    • (1984) EMBO J. , vol.3 , pp. 863-867
    • Engstrom, Y.1    Rozell, B.2    Hansson, H.A.3    Stemme, S.4    Thelander, L.5
  • 20
    • 0024026803 scopus 로고
    • Immunocytochemical evidence for the cytoplasmic localization and differential expression during the cell cycle of the M1 and M2 subunits of mammalian ribonucleotide reductase
    • Engstrom, Y., and Rozell, B. Immunocytochemical evidence for the cytoplasmic localization and differential expression during the cell cycle of the M1 and M2 subunits of mammalian ribonucleotide reductase. EMBO. J., 7: 1615-1620, 1988.
    • (1988) EMBO J. , vol.7 , pp. 1615-1620
    • Engstrom, Y.1    Rozell, B.2
  • 22
    • 0025940113 scopus 로고
    • Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles
    • Isaacs, W. B., Carter, B. S., and Ewing, C. M. Wild-type p53 suppresses growth of human prostate cancer cells containing mutant p53 alleles. Cancer Res., 51: 4716-4720, 1991.
    • (1991) Cancer Res. , vol.51 , pp. 4716-4720
    • Isaacs, W.B.1    Carter, B.S.2    Ewing, C.M.3
  • 23
    • 0036134649 scopus 로고    scopus 로고
    • A potential role of p53 and WOX1 in mitochondrial apoptosis
    • Chang, N. S. A potential role of p53 and WOX1 in mitochondrial apoptosis. Int. J. Mol. Med., 9: 19-24, 2002.
    • (2002) Int. J. Mol. Med. , vol.9 , pp. 19-24
    • Chang, N.S.1
  • 24
    • 0013466484 scopus 로고    scopus 로고
    • Human ribonucleotide reductase subunit, hRRM2 complement p53R2 in response to UV induced repair in p53 mutant cells
    • Zhou, B., Mo, X., Xue, L. L., Liu, X., Qiu, W., and Yen, Y. Human ribonucleotide reductase subunit, hRRM2 complement p53R2 in response to UV induced repair in p53 mutant cells. Proc. Am. Assoc. Cancer Res., 43: 1151, 2002.
    • (2002) Proc. Am. Assoc. Cancer Res. , vol.43 , pp. 1151
    • Zhou, B.1    Mo, X.2    Xue, L.L.3    Liu, X.4    Qiu, W.5    Yen, Y.6
  • 25
    • 0033198464 scopus 로고    scopus 로고
    • Overstatement of ribonucleotide reductase as a mechanism of resistance to 2.2-difluorodeoxycitidine in the human KB cancer cell line
    • Goan, Y. G., Zhou, B. S., Hu, E., Mi, S., and Yen, Y. Overstatement of ribonucleotide reductase as a mechanism of resistance to 2.2-difluorodeoxycitidine in the human KB cancer cell line. Cancer Res., 59: 4204-4207, 1999.
    • (1999) Cancer Res. , vol.59 , pp. 4204-4207
    • Goan, Y.G.1    Zhou, B.S.2    Hu, E.3    Mi, S.4    Yen, Y.5
  • 26
    • 10344266073 scopus 로고
    • Regulation of ribonucleotide reductase activity in mammalian cells
    • Cory, J. G., and Sato, A. Regulation of ribonucleotide reductase activity in mammalian cells. Mol. Cell. Biochem., 53: 257-266, 1983.
    • (1983) Mol. Cell. Biochem. , vol.53 , pp. 257-266
    • Cory, J.G.1    Sato, A.2
  • 27
    • 0025788998 scopus 로고
    • Enhanced malignant transformation induced by expression of a distinct protein domain of ribonucleotide reductase large subunit from herpes simplex virus type 2
    • Ali, M. A., McWeeney, D., Milosavljevic, A., Jurka, J., and Jariwalla, R. J. Enhanced malignant transformation induced by expression of a distinct protein domain of ribonucleotide reductase large subunit from herpes simplex virus type 2. Proc. Natl. Acad. Sci. USA, 88: 8257-8261, 1991.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 8257-8261
    • Ali, M.A.1    McWeeney, D.2    Milosavljevic, A.3    Jurka, J.4    Jariwalla, R.J.5
  • 28
    • 0031938457 scopus 로고    scopus 로고
    • Ribonucleotide reductase overexpression affects metastatic potential in human KB cancer cells
    • Zhou, B. S., Ker, R., and Yen, Y. Ribonucleotide reductase overexpression affects metastatic potential in human KB cancer cells. Clin. Exp. Metastasis, 16: 43-49, 1998.
    • (1998) Clin. Exp. Metastasis , vol.16 , pp. 43-49
    • Zhou, B.S.1    Ker, R.2    Yen, Y.3
  • 29
    • 0033552613 scopus 로고    scopus 로고
    • Regulation of p53 stability
    • Ashcroft, M., and Vousden, K. H. Regulation of p53 stability. Oncogene, 18: 7637-7643, 1999.
    • (1999) Oncogene , vol.18 , pp. 7637-7643
    • Ashcroft, M.1    Vousden, K.H.2
  • 30
    • 0030853074 scopus 로고    scopus 로고
    • Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts
    • Ford, J. M., and Hanawalt, P. C. Expression of wild-type p53 is required for efficient global genomic nucleotide excision repair in UV-irradiated human fibroblasts. J. Biol. Chem., 272: 28073-28080, 1997.
    • (1997) J. Biol. Chem. , vol.272 , pp. 28073-28080
    • Ford, J.M.1    Hanawalt, P.C.2
  • 31
    • 0030731179 scopus 로고    scopus 로고
    • p53-mediated protective responses to UV irradiation
    • Smith, M. L., and Fomace, A. J., Jr. p53-mediated protective responses to UV irradiation. Proc. Natl. Acad. Sci. USA, 94: 12255-12257, 1997.
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 12255-12257
    • Smith, M.L.1    Fomace A.J., Jr.2
  • 33
    • 0036121363 scopus 로고    scopus 로고
    • p53 regulation of DNA excision repair pathways
    • Smith, M. L., and Seo, Y. R. p53 regulation of DNA excision repair pathways. Mutagenesis, 17: 149-156, 2002.
    • (2002) Mutagenesis , vol.17 , pp. 149-156
    • Smith, M.L.1    Seo, Y.R.2
  • 34
    • 0027298576 scopus 로고
    • Induction of cellular p53 activity by DNA-damaging agents and growth arrest
    • Zhan, Q., Carrier, F., and Fomace, A. J., Jr. Induction of cellular p53 activity by DNA-damaging agents and growth arrest. Mol. Cell. Biol., 13: 4242-4250, 1993.
    • (1993) Mol. Cell. Biol. , vol.13 , pp. 4242-4250
    • Zhan, Q.1    Carrier, F.2    Fomace A.J., Jr.3
  • 35
    • 0013528832 scopus 로고    scopus 로고
    • Characterization of enzymatic properties of the human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits
    • Qiu, W., Zhou, B., Darwish, D., Liu, X., Xue, L., and Yen, Y. Characterization of enzymatic properties of the human ribonucleotide reductase holoenzyme reconstituted in vitro from hRRM1, hRRM2, and p53R2 subunits. Proc. Am. Assoc. Cancer Res., 43: 1142, 2002.
    • (2002) Proc. Am. Assoc. Cancer Res. , vol.43 , pp. 1142
    • Qiu, W.1    Zhou, B.2    Darwish, D.3    Liu, X.4    Xue, L.5    Yen, Y.6
  • 36
    • 0028919069 scopus 로고
    • Involvement of the p53 tumour suppressor in repair of UV-type DNA damage
    • Smith, M. L., Chen, I. T., Zhan, Q., O'Connor, P. M., and Fornace, A. J., Jr. Involvement of the p53 tumour suppressor in repair of UV-type DNA damage. Oncogene, 10: 1053-1059, 1995.
    • (1995) Oncogene , vol.10 , pp. 1053-1059
    • Smith, M.L.1    Chen, I.T.2    Zhan, Q.3    O'Connor, P.M.4    Fornace A.J., Jr.5
  • 37
    • 0021133987 scopus 로고
    • Cell cycle-dependent regulation of mammalian ribonucleotide reductase. The S phase-correlated increase in subunit M2 is regulated by de novo protein synthesis
    • Eriksson, S., Graslund, A., Skog, S., Thelander, L., and Tribukait, B. Cell cycle-dependent regulation of mammalian ribonucleotide reductase. The S phase-correlated increase in subunit M2 is regulated by de novo protein synthesis. J. Biol. Chem., 259: 11695-11700, 1984.
    • (1984) J. Biol. Chem. , vol.259 , pp. 11695-11700
    • Eriksson, S.1    Graslund, A.2    Skog, S.3    Thelander, L.4    Tribukait, B.5
  • 38
    • 0025322164 scopus 로고
    • Effect of cyclic AMP on the cell cycle regulation of ribonucleotide reductase M2 subunit messenger RNA concentrations in wild-type and mutant S49 T lymphoma cells
    • Albert, D. A., Nodzenski, E., Yim, G., and Kowalski, J. Effect of cyclic AMP on the cell cycle regulation of ribonucleotide reductase M2 subunit messenger RNA concentrations in wild-type and mutant S49 T lymphoma cells. J. Cell. Physiol., 143, 251-256, 1990.
    • (1990) J. Cell. Physiol. , vol.143 , pp. 251-256
    • Albert, D.A.1    Nodzenski, E.2    Yim, G.3    Kowalski, J.4
  • 39
    • 0034738967 scopus 로고    scopus 로고
    • A ribonucleotide reductase gene is a transcriptional target of p53 and p73
    • Nakano, K., Bálint, E., Ashcroft, M., and Vousden, K. H. A ribonucleotide reductase gene is a transcriptional target of p53 and p73. Oncogene, 19: 4283-4289, 2000.
    • (2000) Oncogene , vol.19 , pp. 4283-4289
    • Nakano, K.1    Bálint, E.2    Ashcroft, M.3    Vousden, K.H.4
  • 40
    • 0024376690 scopus 로고
    • DNA damage induction of ribonucleotide reductase
    • Elledge, S. J., and Davis, R. W. DNA damage induction of ribonucleotide reductase. Mol. Cell. Biol., 9: 4932-4940, 1989.
    • (1989) Mol. Cell. Biol. , vol.9 , pp. 4932-4940
    • Elledge, S.J.1    Davis, R.W.2
  • 41
    • 0032523834 scopus 로고    scopus 로고
    • Expression of ribonucleotide reductase after ionizing radiation in human cervical carcinoma cells
    • Kuo, M. L., and Kinsella, T. J. Expression of ribonucleotide reductase after ionizing radiation in human cervical carcinoma cells. Cancer Res., 58: 2245-2252, 1998.
    • (1998) Cancer Res. , vol.58 , pp. 2245-2252
    • Kuo, M.L.1    Kinsella, T.J.2
  • 42
    • 0022260274 scopus 로고
    • Cell cycle-dependent expression of mammalian ribonucleotide reductase. Differential regulation of the two subunits
    • Engstrom, Y., Eriksson, S., Jildevik, I., Skog, S., Thelander, L., and Tribukait, B. Cell cycle-dependent expression of mammalian ribonucleotide reductase. Differential regulation of the two subunits. J. Biol. Chem., 260: 9114-9116, 1985.
    • (1985) J. Biol. Chem. , vol.260 , pp. 9114-9116
    • Engstrom, Y.1    Eriksson, S.2    Jildevik, I.3    Skog, S.4    Thelander, L.5    Tribukait, B.6
  • 43
    • 0023712808 scopus 로고
    • Ribonucleotide reductase M1 subunit in cellular proliferation, quiescence, and differentiation
    • Mann, G. J., Musgrove, E. A., Fox, R. M., and Thelander, L. Ribonucleotide reductase M1 subunit in cellular proliferation, quiescence, and differentiation. Cancer Res., 48: 5151-5156, 1988.
    • (1988) Cancer Res. , vol.48 , pp. 5151-5156
    • Mann, G.J.1    Musgrove, E.A.2    Fox, R.M.3    Thelander, L.4
  • 44
    • 0027524622 scopus 로고
    • Structure and promoter characterization of the gene encoding the large subunit (R1 protein) of mouse ribonucleotide reductase
    • Björklund, S., Hjortsberg, K., Johansson, E., and Thelander, L. Structure and promoter characterization of the gene encoding the large subunit (R1 protein) of mouse ribonucleotide reductase. Proc. Natl. Acad. Sci. USA, 90: 11322-11326, 1993.
    • (1993) Proc. Natl. Acad. Sci. USA , vol.90 , pp. 11322-11326
    • Björklund, S.1    Hjortsberg, K.2    Johansson, E.3    Thelander, L.4
  • 45
    • 0027073296 scopus 로고
    • Escherichia coli ribonucleotide reductase expression is cell cycle regulated
    • Sun, L., and Fuchs, J. A. Escherichia coli ribonucleotide reductase expression is cell cycle regulated. Mol. Biol. Cell, 3: 1094-1105, 1992.
    • (1992) Mol. Biol. Cell , vol.3 , pp. 1094-1105
    • Sun, L.1    Fuchs, J.A.2
  • 46
    • 0016267499 scopus 로고
    • Nuclear and cytoplasmic pools of deoxyribonucleoside triphosphates in Chinese hamster ovary cells
    • Skoog, L., and Bjursell, G. Nuclear and cytoplasmic pools of deoxyribonucleoside triphosphates in Chinese hamster ovary cells. J. Biol. Chem., 249: 6434-6438, 1974.
    • (1974) J. Biol. Chem. , vol.249 , pp. 6434-6438
    • Skoog, L.1    Bjursell, G.2
  • 47
    • 0034594895 scopus 로고    scopus 로고
    • p53 sends nucleotides to repair DNA
    • Lozano, G., and Elledge, S. J. p53 sends nucleotides to repair DNA. Nature (Lond.), 404: 24-25, 2000.
    • (2000) Nature (Lond.) , vol.404 , pp. 24-25
    • Lozano, G.1    Elledge, S.J.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.