Roles of ceramide and sphingolipids in pancreatic β-cell function and dysfunction

Islets

Volumn 4, Issue 3, 2012, Pages 177-187

  Boslem, Ebru ^a,b   Meikle, Peter J ^c   Biden, Trevor J ^a,b  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

^b UNIVERSITY OF NEW SOUTH WALES   (Australia)

^c BAKER IDI HEART AND DIABETES INSTITUTE   (Australia)

Author keywords

Apoptosis; Ceramide; Endoplasmic reticulum stress; Islet; Lipidomics; Lipotoxicity; Palmitate; Pancreatic cell; Trafficking; Type 1 diabetes; Type 2 diabetes

Indexed keywords

BETA GLUCOSYLCERAMIDE; BETA LACTOSYLCERAMIDE; CERAMIDE; ENZYME INHIBITOR; FINGOLIMOD; GALACTOSYLCERAMIDE; GANGLIOSIDE; GANGLIOSIDE GM2; GENZ 123346; GLUCOSYLCERAMIDE; GLYCOSPHINGOLIPID; INSULIN; SERINE PALMITOYLTRANSFERASE; SERINE PALMITOYLTRANSFERASE INHIBITOR; SPHINGOLIPID; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOSINE 1 PHOSPHATE; SULFATIDE; UNCLASSIFIED DRUG;

AUTOIMMUNITY; CELL MIGRATION; CYTOKINE RELEASE; EXOCYTOSIS; GENE EXPRESSION; GOLGI COMPLEX; INSULIN DEPENDENT DIABETES MELLITUS; LIPID METABOLISM; LIPOTOXICITY; NON INSULIN DEPENDENT DIABETES MELLITUS; PANCREAS ISLET CELL FUNCTION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CERAMIDES; DIABETES MELLITUS, TYPE 1; DIABETES MELLITUS, TYPE 2; HUMANS; INSULIN-SECRETING CELLS; SIGNAL TRANSDUCTION; SPHINGOLIPIDS;

EID: 84864396455     PISSN: 19382014     EISSN: 19382022     Source Type: Journal    
DOI: 10.4161/isl.20102     Document Type: Review

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