Ceramide generation is sufficient to account for the inhibition of the insulin-stimulated PKB pathway in C2C12 skeletal muscle cells pretreated with palmitate

Journal of Biological Chemistry

Volumn 274, Issue 34, 1999, Pages 24202-24210

  Schmitz Peiffer, Carsten ^a   Craig, Denby L ^a   Biden, Trevor J ^a  

^a GARVAN INSTITUTE OF MEDICAL RESEARCH   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

CERAMIDE; GLYCOGEN; INSULIN; LINOLEIC ACID; MITOGEN ACTIVATED PROTEIN KINASE; OLEIC ACID; PALMITIC ACID; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE; PROTEIN KINASE B;

ANIMAL CELL; ARTICLE; CELL LEVEL; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME PHOSPHORYLATION; ENZYME REGULATION; GLYCOGEN SYNTHESIS; INSULIN RESISTANCE; MOLECULAR DYNAMICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; REGULATORY MECHANISM; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CA(2+)-CALMODULIN DEPENDENT PROTEIN KINASE; CELLS, CULTURED; CERAMIDES; GLYCOGEN; GLYCOGEN SYNTHASE KINASES; INSULIN; INSULIN RESISTANCE; MICE; MUSCLE, SKELETAL; PALMITIC ACID; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RESPONSE ELEMENTS;

ANIMALIA;

EID: 0033588253     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.274.34.24202     Document Type: Article

References (48)

1. DeFronzo, R. A., Gunnarsson, R., Bjorkman, O., Olsson, M., and Wahren, J. (1985) J. Clin. Invest. 76, 149-155
2. McGarry, J. D. (1992) Science 258, 766-770
3. Borkman, M., Storlien, L. H., Pan, D. A., Jenkins, A. B., Chisholm, D. J., and Campbell, L. V. (1993) N. Engl. J. Med. 328, 238-244
4. Goodyear, L. J., Giorgino, F., Sherman, L. A., Carey, J., Smith, R. J., and Dohm, G. L. (1995) J. Clin. Invest. 95, 2195-2204
5. Villarpalasi, C., and Farese, R. V. (1994) Diabetologia 37, 885-888
6. Storlien, L. H., Kraegen, E. W., Chisholm, D. J., Ford, G. L., Bruce, D. G., and Pascoe, W. S. (1987) Science 237, 885-888
7. Kraegen, E. W., Clark, P. W., Jenkins, A. B., Daley, E. A., Chisholm, D. J., and Storlien, L. H. (1991) Diabetes 40, 1397-1403
8. Eckel, J., and Reinauer, H. (1990) Biochem. Soc. Trans. 18, 1125-1127
9. Shillabeer, G., Chamoun, C., Hatch, G., and Lau, D. C. W. (1995) Biochem. Biophys. Res. Commun. 207, 768-774
10. Lawrence, J. C., and Roach, P. J. (1997) Diabetes 46, 541-547
11. White, M. F. (1998) Mol. Cell. Biochem. 182, 3-11
12. Yamauchi, T., Tobe, K., Tamemoto, H., Ueki, K., Kaburagi, Y., Yamamotohonda, R., Takahashi, Y., Yoshizawa, F., Aizawa, S., Akanuma, Y., Sonenberg, N., Yazaki, Y., and Kadowaki, T. (1996) Mol. Cell. Biol. 16, 3074-3084
13. White, M. F. (1997) Diabetologia 40, Suppl. 2, 2-17
14. Alessi, D. R., and Cohen, P. (1998) Curr. Opin. Gen. Dev. 8, 55-62
15. Cross, D. A. E., Alessi, D. R., Cohen, P., Andjelkovich, M., and Hemmings, B. A. (1995) Nature 378, 785-789
16. Skurat, A. V., and Roach, P. J. (1995) J. Biol. Chem. 270, 12491-12497
17. Ragolia, L., and Begum, N. (1998) Mol. Cell. Biochem. 182, 49-58
18. Holness, M. J., Fryer, L., and Sugden, M. C. (1997) Biochem. Soc. Trans. 25, 1-7
19. Shulman, G. I., Rothman, D. L., Jue, T., Stein, P., DeFronzo, R. A., and Shulman, R. G. (1990) N. Engl. J. Med. 322, 223-228
20. Moxham, C. M., Tabrizchi, A., Davis, R. J., and Malbon, C. C. (1996) J. Biol. Chem. 271, 30765-30773
21. Guo, J. H., Wang, H., and Malbon, C. C. (1998) J. Biol. Chem. 273, 16487-16493
22. Randle, P. J., Kerbey, A. L., and Espinal, J. (1988) Diabetes Metab. Rev. 4, 623-638
23. Schmitz-Peiffer, C., Browne, C. L., Oakes, N. D., Watkinson, A., Chisholm, D. J., Kraegen, E. W., and Biden, T. J. (1997) Diabetes 46, 169-178
24. Schmitz-Peiffer, C., Oakes, N. D., Browne, C. L., Kraegen, E. W., and Biden, T. J. (1997) Am. J. Physiol. 273, E915-E921
25. Basu, S., Bayoumy, S., Zhang, Y., Lozano, J., and Kolesnick, R (1998) J. Biol. Chem. 273, 30419-30426
26. Zhou, H. L., Summers, S. K., Birnbaum, M. J., and Pittman, R. N. (1998) J. Biol. Chem. 273, 16568-16575
27. Summers, S. A., Garza, L. A., Zhou, H. L., and Birnbaum, M. J. (1998) Mol. Cell. Biol. 18, 5457-5464
28. Merrill, A., Jr., and Jones, D. D. (1990) Biochim. Biophys. Acta 1044, 1-12
29. Svedberg, J., Bjorntorp, P., Smith, U., and Lonnroth, P. (1990) Diabetes 39, 570-574
30. Berti, L., Kellerer, M., Capp, E., and Haring, H. U. (1997) Diabetologia 40, 606-609
31. Bradford, M. M. (1976) Anal. Biochem. 72, 248-254
32. Ferre, P., Leturque, A., Burnol, A. F., Penicaud, L., and Girard, J. (1985) Biochem. J. 228, 103-110
33. Folli, F., Saad, M. J. A., Backer, J. M., and Kahn, C. R. (1992) J. Biol. Chem. 267, 22171-22177
34. Bjornholm, M., Kawano, Y., Lehtihet, M., and Zierath, J. R. (1997) Diabetes 46, 524-527
35. Laemmli, U. K. (1970) Nature 227, 680-685
36. Turinsky, J., O'Sullivan, D. M., and Bayly, B. P. (1990) J. Biol. Chem. 265, 16880-16885
37. Martin, A., Duffy, P. A., Liossis, C., Gomezmunoz, A., Obrien, L., Stone, J. C., and Brindley, D. N. (1997) Oncogene 14, 1571-1580
38. Gorski, J., Nawrocki, A., and Murthy, M. (1998) Mol. Cell. Biochem. 178, 113-118
39. Moyers, J. S., Bilan, P. J., Reynet, C., and Kahn, C. R. (1996) J. Biol. Chem. 271, 23111-23116
40. Ogihara, T., Shin, B. C., Anai, M., Katagiri, H., Inukai, K., Funaki, M., Fukushima, Y., Ishihara, H., Takata, K., Kikuchi, M., Yazaki, Y., Oka, Y., and Asano, T. (1997) J. Biol. Chem. 272, 12868-12873
41. Wang, C. N., Obrien, L., and Brindley, D. N. (1998) Diabetes 47, 24-31
42. Kolesnick, R., and Kronke, M. (1998) Ann. Rev. Physiol. 60, 643-665
43. Meier, R., Thelen, M., and Hemmings, B. A. (1998) EMBO J. 17, 7294-7303
44. Hannun, Y. A. (1994) J. Biol. Chem. 269, 3125-3128
45. Hunnicutt, J. W., Hardy, R. W., Williford, J., and McDonald, J. M. (1994) Diabetes 43, 540-545
46. Van Epps-Fung, M., Williford, J., Wells, A., and Hardy, R. W. (1997) Endocrinology 138, 4338-4345
47. Eckel, J., Asskamp, B., and Reinauer, H. (1991) Endocrinology 129, 345-352
48. Usui, I., Takata, Y., Imamura, T., Morioka, H., Sasaoka, T., Sawa, T., Ishihara, H., Ishiki, M., and Kobayashi, M. (1997) Diabetologia 40, 894-901