Inhibition of foxo1 protects pancreatic islet β-cells against fatty acid and endoplasmic reticulum stress-induced apoptosis

Diabetes

Volumn 57, Issue 4, 2008, Pages 846-859

  Martinez, Sara C ^a   Tanabe, Katsuya ^a   Cras Méneur, Corentin ^a   Abumrad, Nada A ^a   Bernal Mizrachi, Ernesto ^a   Permutt, M Alan ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CCAAT ENHANCER BINDING PROTEIN; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; INSULIN; OLEIC ACID; PALMITIC ACID; PROTEIN KINASE B; TRANSCRIPTION FACTOR FKHR; FATTY ACID; FORKHEAD TRANSCRIPTION FACTOR; FOXO1 PROTEIN, MOUSE; PROPIDIUM IODIDE; UNCLASSIFIED DRUG;

ADENOVIRUS; ALLELE; ANIMAL CELL; ANIMAL EXPERIMENT; APOPTOSIS; ARTICLE; CELL SURVIVAL; ENDOPLASMIC RETICULUM STRESS; GENE EXPRESSION; INSULINOMA; MALE; MICROARRAY ANALYSIS; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; WESTERN BLOTTING; ANIMAL; C57BL MOUSE; CELL DEATH; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; ENDOPLASMIC RETICULUM; GENETICS; MECHANICAL STRESS; PHYSIOLOGY; PLASMID; REPORTER GENE; SIGNAL TRANSDUCTION; TRANSGENIC MOUSE; TUMOR CELL LINE;

ANIMALS; APOPTOSIS; CELL DEATH; CELL LINE, TUMOR; ENDOPLASMIC RETICULUM; FATTY ACIDS, NONESTERIFIED; FORKHEAD TRANSCRIPTION FACTORS; GENES, REPORTER; INSULIN-SECRETING CELLS; INSULINOMA; MALE; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OLEIC ACID; PALMITIC ACID; PLASMIDS; PROPIDIUM; SIGNAL TRANSDUCTION; STRESS, MECHANICAL;

EID: 42449126643     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db07-0595     Document Type: Article

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