Chronic effects of palmitate overload on nutrient-induced insulin secretion and autocrine signalling in pancreatic MIN6 beta cells

PLoS ONE

Volumn 6, Issue 10, 2011, Pages

  Watson, Maria L ^a   Macrae, Katherine ^a   Marley, Anna E ^b   Hundal, Harinder S ^a  

^a UNIVERSITY OF DUNDEE   (United Kingdom)

^b ASTRAZENECA   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

2 BROMOPALMITIC ACID; AMINO ACID; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CERAMIDE; DIACYLGLYCEROL; GLUCOSE; INSULIN; MITOGEN ACTIVATED PROTEIN KINASE; PALMITIC ACID; PROTEIN KINASE B; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; PALMITIC ACID DERIVATIVE;

ANIMAL CELL; ARTICLE; AUTOCRINE EFFECT; CONTROLLED STUDY; ENZYME ACTIVATION; ESTERIFICATION; FATTY ACID OXIDATION; FATTY ACID TRANSPORT; INSULIN RELEASE; LIPOGENESIS; MITOCHONDRION; MOUSE; NONHUMAN; NUTRIENT; PANCREAS ISLET BETA CELL; ANIMAL; APOPTOSIS; CELL LINE; CYTOLOGY; DRUG EFFECT; METABOLISM; SECRETION; SIGNAL TRANSDUCTION; TIME;

AMINO ACIDS; ANIMALS; APOPTOSIS; AUTOCRINE COMMUNICATION; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL LINE; ENZYME ACTIVATION; GLUCOSE; INSULIN; INSULIN-SECRETING CELLS; MITOGEN-ACTIVATED PROTEIN KINASE 1; MITOGEN-ACTIVATED PROTEIN KINASE 3; PALMITATES; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 80053578696     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0025975     Document Type: Article

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