-
1
-
-
0024299087
-
The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein
-
Hashimoto C, Hudson KL, Anderson KV. The Toll gene of Drosophila, required for dorsal-ventral embryonic polarity, appears to encode a transmembrane protein. Cell 1988; 52:269-79.
-
(1988)
Cell
, vol.52
, pp. 269-279
-
-
Hashimoto, C.1
Hudson, K.L.2
Anderson, K.V.3
-
2
-
-
0030831210
-
A human homologue of the Drosophila Toll protein signals activation of adaptive immunity
-
Medzhitov R, Preston-Hurlburt P, Janeway CA Jr. A human homologue of the Drosophila Toll protein signals activation of adaptive immunity. Nature 1997; 388:394-7.
-
(1997)
Nature
, vol.388
, pp. 394-397
-
-
Medzhitov, R.1
Preston-Hurlburt, P.2
Janeway Jr., C.A.3
-
3
-
-
0032509295
-
Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene
-
Poltorak A, He X, Smirnova I et al. Defective LPS signaling in C3H/HeJ and C57BL/10ScCr mice: mutations in Tlr4 gene. Science 1998; 282:2085-8.
-
(1998)
Science
, vol.282
, pp. 2085-2088
-
-
Poltorak, A.1
He, X.2
Smirnova, I.3
-
4
-
-
0035953543
-
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
-
Hayashi F, Smith KD, Ozinsky A et al. The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5. Nature 2001; 410:1099-103.
-
(2001)
Nature
, vol.410
, pp. 1099-1103
-
-
Hayashi, F.1
Smith, K.D.2
Ozinsky, A.3
-
5
-
-
0034922923
-
Discrimination of bacterial lipoproteins by Toll-like receptor 6
-
Takeuchi O, Kawai T, Muhlradt PF, Morr M, Radolf JD, Zychlinsky A, Takeda K, Akira S. Discrimination of bacterial lipoproteins by Toll-like receptor 6. Int Immunol 2001; 13:933-40.
-
(2001)
Int Immunol
, vol.13
, pp. 933-940
-
-
Takeuchi, O.1
Kawai, T.2
Muhlradt, P.F.3
Morr, M.4
Radolf, J.D.5
Zychlinsky, A.6
Takeda, K.7
Akira, S.8
-
6
-
-
0033580949
-
Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2
-
Schwandner R, Dziarski R, Wesche H, Rothe M, Kirschning CJ. Peptidoglycan- and lipoteichoic acid-induced cell activation is mediated by toll-like receptor 2. J Biol Chem 1999; 274:17406-9.
-
(1999)
J Biol Chem
, vol.274
, pp. 17406-17409
-
-
Schwandner, R.1
Dziarski, R.2
Wesche, H.3
Rothe, M.4
Kirschning, C.J.5
-
7
-
-
1542317550
-
Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA
-
Diebold SS, Kaisho T, Hemmi H, Akira S, Reis e Sousa C. Innate antiviral responses by means of TLR7-mediated recognition of single-stranded RNA. Science 2004; 303:1529-31.
-
(2004)
Science
, vol.303
, pp. 1529-1531
-
-
Diebold, S.S.1
Kaisho, T.2
Hemmi, H.3
Akira, S.4
Reis e Sousa, C.5
-
8
-
-
0034619794
-
A Toll-like receptor recognizes bacterial DNA
-
Hemmi H, Takeuchi O, Kawai T et al. A Toll-like receptor recognizes bacterial DNA. Nature 2000; 408:740-5.
-
(2000)
Nature
, vol.408
, pp. 740-745
-
-
Hemmi, H.1
Takeuchi, O.2
Kawai, T.3
-
9
-
-
0035909372
-
Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3
-
Alexopoulou L, Holt AC, Medzhitov R, Flavell RA. Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3. Nature 2001; 413:732-8.
-
(2001)
Nature
, vol.413
, pp. 732-738
-
-
Alexopoulou, L.1
Holt, A.C.2
Medzhitov, R.3
Flavell, R.A.4
-
10
-
-
40749098665
-
UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes
-
Kim YM, Brinkmann MM, Paquet ME, Ploegh HL. UNC93B1 delivers nucleotide-sensing toll-like receptors to endolysosomes. Nature 2008; 452:234-8.
-
(2008)
Nature
, vol.452
, pp. 234-238
-
-
Kim, Y.M.1
Brinkmann, M.M.2
Paquet, M.E.3
Ploegh, H.L.4
-
11
-
-
34247484007
-
The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling
-
Brinkmann MM, Spooner E, Hoebe K, Beutler B, Ploegh HL, Kim YM. The interaction between the ER membrane protein UNC93B and TLR3, 7, and 9 is crucial for TLR signaling. J Cell Biol 2007; 177:265-75.
-
(2007)
J Cell Biol
, vol.177
, pp. 265-275
-
-
Brinkmann, M.M.1
Spooner, E.2
Hoebe, K.3
Beutler, B.4
Ploegh, H.L.5
Kim, Y.M.6
-
12
-
-
79960470158
-
Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking
-
Fukui R, Saitoh S, Kanno A et al. Unc93B1 restricts systemic lethal inflammation by orchestrating Toll-like receptor 7 and 9 trafficking. Immunity 2011; 35:69-81.
-
(2011)
Immunity
, vol.35
, pp. 69-81
-
-
Fukui, R.1
Saitoh, S.2
Kanno, A.3
-
13
-
-
1542377424
-
A toll-like receptor that prevents infection by uropathogenic bacteria
-
Zhang D, Zhang G, Hayden MS, Greenblatt MB, Bussey C, Flavell RA, Ghosh S. A toll-like receptor that prevents infection by uropathogenic bacteria. Science 2004; 303:1522-6.
-
(2004)
Science
, vol.303
, pp. 1522-1526
-
-
Zhang, D.1
Zhang, G.2
Hayden, M.S.3
Greenblatt, M.B.4
Bussey, C.5
Flavell, R.A.6
Ghosh, S.7
-
14
-
-
20644433342
-
TLR11 activation of dendritic cells by a protozoan profilin-like protein
-
Yarovinsky F, Zhang D, Andersen JF et al. TLR11 activation of dendritic cells by a protozoan profilin-like protein. Science 2005; 308:1626-9.
-
(2005)
Science
, vol.308
, pp. 1626-1629
-
-
Yarovinsky, F.1
Zhang, D.2
Andersen, J.F.3
-
15
-
-
74549167783
-
Regulation of adaptive immunity by the innate immune system
-
Iwasaki A, Medzhitov R. Regulation of adaptive immunity by the innate immune system. Science 2010; 327:291-5.
-
(2010)
Science
, vol.327
, pp. 291-295
-
-
Iwasaki, A.1
Medzhitov, R.2
-
16
-
-
84859243942
-
Differential impact of Toll-like receptor signaling on distinct B cell subpopulations
-
Meyer-Bahlburg A, Rawlings DJ. Differential impact of Toll-like receptor signaling on distinct B cell subpopulations. Front Biosci 2011; 17:1499-516.
-
(2011)
Front Biosci
, vol.17
, pp. 1499-1516
-
-
Meyer-Bahlburg, A.1
Rawlings, D.J.2
-
17
-
-
0036570169
-
Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides
-
Hornung V, Rothenfusser S, Britsch S, Krug A, Jahrsdorfer B, Giese T, Endres S, Hartmann G. Quantitative expression of toll-like receptor 1-10 mRNA in cellular subsets of human peripheral blood mononuclear cells and sensitivity to CpG oligodeoxynucleotides. J Immunol 2002; 168:4531-7.
-
(2002)
J Immunol
, vol.168
, pp. 4531-4537
-
-
Hornung, V.1
Rothenfusser, S.2
Britsch, S.3
Krug, A.4
Jahrsdorfer, B.5
Giese, T.6
Endres, S.7
Hartmann, G.8
-
18
-
-
33746053199
-
A distinct Toll-like receptor repertoire in human tonsillar B cells, directly activated by PamCSK, R-837 and CpG-2006 stimulation
-
Mansson A, Adner M, Hockerfelt U, Cardell LO. A distinct Toll-like receptor repertoire in human tonsillar B cells, directly activated by PamCSK, R-837 and CpG-2006 stimulation. Immunology 2006; 118:539-48.
-
(2006)
Immunology
, vol.118
, pp. 539-548
-
-
Mansson, A.1
Adner, M.2
Hockerfelt, U.3
Cardell, L.O.4
-
19
-
-
79953892799
-
TLR1/2, TLR7, and TLR9 signals directly activate human peripheral blood naive and memory B cell subsets to produce cytokines, chemokines, and hematopoietic growth factors
-
Agrawal S, Gupta S. TLR1/2, TLR7, and TLR9 signals directly activate human peripheral blood naive and memory B cell subsets to produce cytokines, chemokines, and hematopoietic growth factors. J Clin Immunol 2010; 31:89-98.
-
(2010)
J Clin Immunol
, vol.31
, pp. 89-98
-
-
Agrawal, S.1
Gupta, S.2
-
20
-
-
0038142387
-
A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells
-
Bernasconi NL, Onai N, Lanzavecchia A. A role for Toll-like receptors in acquired immunity: up-regulation of TLR9 by BCR triggering in naive B cells and constitutive expression in memory B cells. Blood 2003; 101:4500-4.
-
(2003)
Blood
, vol.101
, pp. 4500-4504
-
-
Bernasconi, N.L.1
Onai, N.2
Lanzavecchia, A.3
-
21
-
-
0041743207
-
The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells
-
Bourke E, Bosisio D, Golay J, Polentarutti N, Mantovani A. The toll-like receptor repertoire of human B lymphocytes: inducible and selective expression of TLR9 and TLR10 in normal and transformed cells. Blood 2003; 102:956-63.
-
(2003)
Blood
, vol.102
, pp. 956-963
-
-
Bourke, E.1
Bosisio, D.2
Golay, J.3
Polentarutti, N.4
Mantovani, A.5
-
22
-
-
70449371316
-
Plasma cell toll-like receptor (TLR) expression differs from that of B cells, and plasma cell TLR triggering enhances immunoglobulin production
-
Dorner M, Brandt S, Tinguely M et al. Plasma cell toll-like receptor (TLR) expression differs from that of B cells, and plasma cell TLR triggering enhances immunoglobulin production. Immunology 2009; 128:573-9.
-
(2009)
Immunology
, vol.128
, pp. 573-579
-
-
Dorner, M.1
Brandt, S.2
Tinguely, M.3
-
23
-
-
41149150143
-
Toll-like receptor expression and responsiveness of distinct murine splenic and mucosal B-cell subsets
-
e863.
-
Gururajan M, Jacob J, Pulendran B. Toll-like receptor expression and responsiveness of distinct murine splenic and mucosal B-cell subsets. PLoS ONE 2007; 2:e863.
-
(2007)
PLoS ONE
, vol.2
-
-
Gururajan, M.1
Jacob, J.2
Pulendran, B.3
-
24
-
-
34250192856
-
TLR agonists selectively promote terminal plasma cell differentiation of B cell subsets specialized in thymus-independent responses
-
Genestier L, Taillardet M, Mondiere P, Gheit H, Bella C, Defrance T. TLR agonists selectively promote terminal plasma cell differentiation of B cell subsets specialized in thymus-independent responses. J Immunol 2007; 178:7779-86.
-
(2007)
J Immunol
, vol.178
, pp. 7779-7786
-
-
Genestier, L.1
Taillardet, M.2
Mondiere, P.3
Gheit, H.4
Bella, C.5
Defrance, T.6
-
25
-
-
0015834152
-
Proliferation of B and T cells in mixed lymphocyte cultures
-
Andersson LC, Nordling S, Hayry P. Proliferation of B and T cells in mixed lymphocyte cultures. J Exp Med 1973; 138:324-9.
-
(1973)
J Exp Med
, vol.138
, pp. 324-329
-
-
Andersson, L.C.1
Nordling, S.2
Hayry, P.3
-
26
-
-
34548314455
-
Polyinosinic acid is a ligand for toll-like receptor 3
-
Marshall-Clarke S, Downes JE, Haga IR, Bowie AG, Borrow P, Pennock JL, Grencis RK, Rothwell P. Polyinosinic acid is a ligand for toll-like receptor 3. J Biol Chem 2007; 282:24759-66.
-
(2007)
J Biol Chem
, vol.282
, pp. 24759-24766
-
-
Marshall-Clarke, S.1
Downes, J.E.2
Haga, I.R.3
Bowie, A.G.4
Borrow, P.5
Pennock, J.L.6
Grencis, R.K.7
Rothwell, P.8
-
27
-
-
33846526235
-
Influenza virus infection causes global respiratory tract B cell response modulation via innate immune signals
-
Chang WL, Coro ES, Rau FC, Xiao Y, Erle DJ, Baumgarth N. Influenza virus infection causes global respiratory tract B cell response modulation via innate immune signals. J Immunol 2007; 178:1457-67.
-
(2007)
J Immunol
, vol.178
, pp. 1457-1467
-
-
Chang, W.L.1
Coro, E.S.2
Rau, F.C.3
Xiao, Y.4
Erle, D.J.5
Baumgarth, N.6
-
28
-
-
27544434183
-
Essential function for the kinase TAK1 in innate and adaptive immune responses
-
Sato S, Sanjo H, Takeda K et al. Essential function for the kinase TAK1 in innate and adaptive immune responses. Nat Immunol 2005; 6:1087-95.
-
(2005)
Nat Immunol
, vol.6
, pp. 1087-1095
-
-
Sato, S.1
Sanjo, H.2
Takeda, K.3
-
29
-
-
15444364398
-
Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN
-
Bekeredjian-Ding IB, Wagner M, Hornung V, Giese T, Schnurr M, Endres S, Hartmann G. Plasmacytoid dendritic cells control TLR7 sensitivity of naive B cells via type I IFN. J Immunol 2005; 174:4043-50.
-
(2005)
J Immunol
, vol.174
, pp. 4043-4050
-
-
Bekeredjian-Ding, I.B.1
Wagner, M.2
Hornung, V.3
Giese, T.4
Schnurr, M.5
Endres, S.6
Hartmann, G.7
-
30
-
-
0034123135
-
Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells
-
Muzio M, Bosisio D, Polentarutti N et al. Differential expression and regulation of toll-like receptors (TLR) in human leukocytes: selective expression of TLR3 in dendritic cells. J Immunol 2000; 164:5998-6004.
-
(2000)
J Immunol
, vol.164
, pp. 5998-6004
-
-
Muzio, M.1
Bosisio, D.2
Polentarutti, N.3
-
31
-
-
0035164253
-
Regulation of Toll-like receptors in human monocytes and dendritic cells
-
Visintin A, Mazzoni A, Spitzer JH, Wyllie DH, Dower SK, Segal DM. Regulation of Toll-like receptors in human monocytes and dendritic cells. J Immunol 2001; 166:249-55.
-
(2001)
J Immunol
, vol.166
, pp. 249-255
-
-
Visintin, A.1
Mazzoni, A.2
Spitzer, J.H.3
Wyllie, D.H.4
Dower, S.K.5
Segal, D.M.6
-
32
-
-
0038242875
-
Toll-like receptor signaling pathways
-
Barton GM, Medzhitov R. Toll-like receptor signaling pathways. Science 2003; 300:1524-5.
-
(2003)
Science
, vol.300
, pp. 1524-1525
-
-
Barton, G.M.1
Medzhitov, R.2
-
33
-
-
33748871187
-
The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling
-
Carty M, Goodbody R, Schroder M, Stack J, Moynagh PN, Bowie AG. The human adaptor SARM negatively regulates adaptor protein TRIF-dependent Toll-like receptor signaling. Nat Immunol 2006; 7:1074-81.
-
(2006)
Nat Immunol
, vol.7
, pp. 1074-1081
-
-
Carty, M.1
Goodbody, R.2
Schroder, M.3
Stack, J.4
Moynagh, P.N.5
Bowie, A.G.6
-
34
-
-
34247566510
-
The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling
-
O'Neill LA, Bowie AG. The family of five: TIR-domain-containing adaptors in Toll-like receptor signalling. Nat Rev Immunol 2007; 7:353-64.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 353-364
-
-
O'Neill, L.A.1
Bowie, A.G.2
-
35
-
-
70349443224
-
Transcriptional control of the inflammatory response
-
Medzhitov R, Horng T. Transcriptional control of the inflammatory response. Nat Rev Immunol 2009; 9:692-703.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 692-703
-
-
Medzhitov, R.1
Horng, T.2
-
36
-
-
81055129618
-
Systematic discovery of TLR signaling components delineates viral-sensing circuits
-
Chevrier N, Mertins P, Artyomov MN et al. Systematic discovery of TLR signaling components delineates viral-sensing circuits. Cell 2011; 147:853-67.
-
(2011)
Cell
, vol.147
, pp. 853-867
-
-
Chevrier, N.1
Mertins, P.2
Artyomov, M.N.3
-
37
-
-
70349882120
-
Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses
-
Amit I, Garber M, Chevrier N et al. Unbiased reconstruction of a mammalian transcriptional network mediating pathogen responses. Science 2009; 326:257-63.
-
(2009)
Science
, vol.326
, pp. 257-263
-
-
Amit, I.1
Garber, M.2
Chevrier, N.3
-
38
-
-
33846351610
-
Genetic analysis of the innate immune responses in wild-derived inbred strains of mice
-
Stephan K, Smirnova I, Jacque B, Poltorak A. Genetic analysis of the innate immune responses in wild-derived inbred strains of mice. Eur J Immunol 2007; 37:212-23.
-
(2007)
Eur J Immunol
, vol.37
, pp. 212-223
-
-
Stephan, K.1
Smirnova, I.2
Jacque, B.3
Poltorak, A.4
-
39
-
-
34547881895
-
TLR9 stimulation drives naive B cells to proliferate and to attain enhanced antigen presenting function
-
Jiang W, Lederman MM, Harding CV, Rodriguez B, Mohner RJ, Sieg SF. TLR9 stimulation drives naive B cells to proliferate and to attain enhanced antigen presenting function. Eur J Immunol 2007; 37:2205-13.
-
(2007)
Eur J Immunol
, vol.37
, pp. 2205-2213
-
-
Jiang, W.1
Lederman, M.M.2
Harding, C.V.3
Rodriguez, B.4
Mohner, R.J.5
Sieg, S.F.6
-
40
-
-
40449137383
-
CpG drives human transitional B cells to terminal differentiation and production of natural antibodies
-
Capolunghi F, Cascioli S, Giorda E et al. CpG drives human transitional B cells to terminal differentiation and production of natural antibodies. J Immunol 2008; 180:800-8.
-
(2008)
J Immunol
, vol.180
, pp. 800-808
-
-
Capolunghi, F.1
Cascioli, S.2
Giorda, E.3
-
41
-
-
0023889066
-
Mitogen- and IL-4-regulated expression of germ-line Igγ 2b transcripts: evidence for directed heavy chain class switching
-
Lutzker S, Rothman P, Pollock R, Coffman R, Alt FW. Mitogen- and IL-4-regulated expression of germ-line Igγ 2b transcripts: evidence for directed heavy chain class switching. Cell 1988; 53:177-84.
-
(1988)
Cell
, vol.53
, pp. 177-184
-
-
Lutzker, S.1
Rothman, P.2
Pollock, R.3
Coffman, R.4
Alt, F.W.5
-
42
-
-
4644241216
-
CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10
-
He B, Qiao X, Cerutti A. CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10. J Immunol 2004; 173:4479-91.
-
(2004)
J Immunol
, vol.173
, pp. 4479-4491
-
-
He, B.1
Qiao, X.2
Cerutti, A.3
-
43
-
-
47949102460
-
Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF
-
Xu W, Santini PA, Matthews AJ, Chiu A, Plebani A, He B, Chen K, Cerutti A. Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF. J Immunol 2008; 181:276-87.
-
(2008)
J Immunol
, vol.181
, pp. 276-287
-
-
Xu, W.1
Santini, P.A.2
Matthews, A.J.3
Chiu, A.4
Plebani, A.5
He, B.6
Chen, K.7
Cerutti, A.8
-
44
-
-
49249088078
-
Comparison of human B cell activation by TLR7 and TLR9 agonists
-
39.
-
Hanten JA, Vasilakos JP, Riter CL, Neys L, Lipson KE, Alkan SS, Birmachu W. Comparison of human B cell activation by TLR7 and TLR9 agonists. BMC Immunol 2008; 9:39.
-
(2008)
BMC Immunol
, vol.9
-
-
Hanten, J.A.1
Vasilakos, J.P.2
Riter, C.L.3
Neys, L.4
Lipson, K.E.5
Alkan, S.S.6
Birmachu, W.7
-
45
-
-
53549135771
-
+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6
-
+, that strongly express cell surface Toll-like receptor 9 and secrete high levels of interleukin-6. Immunology 2008; 125:430-7.
-
(2008)
Immunology
, vol.125
, pp. 430-437
-
-
Cognasse, F.1
Hamzeh-Cognasse, H.2
Lafarge, S.3
Chavarin, P.4
Pozzetto, B.5
Richard, Y.6
Garraud, O.7
-
46
-
-
64249093402
-
Reduced c-myc expression levels limit follicular mature B cell cycling in response to TLR signals
-
Meyer-Bahlburg A, Bandaranayake AD, Andrews SF, Rawlings DJ. Reduced c-myc expression levels limit follicular mature B cell cycling in response to TLR signals. J Immunol 2009; 182:4065-75.
-
(2009)
J Immunol
, vol.182
, pp. 4065-4075
-
-
Meyer-Bahlburg, A.1
Bandaranayake, A.D.2
Andrews, S.F.3
Rawlings, D.J.4
-
48
-
-
2942748202
-
CpG DNA redirects class-switching towards "Th1-like" Ig isotype production via TLR9 and MyD88
-
Lin L, Gerth AJ, Peng SL. CpG DNA redirects class-switching towards "Th1-like" Ig isotype production via TLR9 and MyD88. Eur J Immunol 2004; 34:1483-7.
-
(2004)
Eur J Immunol
, vol.34
, pp. 1483-1487
-
-
Lin, L.1
Gerth, A.J.2
Peng, S.L.3
-
49
-
-
77955380255
-
Interleukin-10 mediated autoregulation of murine B-1 B-cells and its role in Borrelia hermsii infection
-
e11445.
-
Sindhava V, Woodman ME, Stevenson B, Bondada S. Interleukin-10 mediated autoregulation of murine B-1 B-cells and its role in Borrelia hermsii infection. PLoS ONE 2010; 5:e11445.
-
(2010)
PLoS ONE
, vol.5
-
-
Sindhava, V.1
Woodman, M.E.2
Stevenson, B.3
Bondada, S.4
-
50
-
-
73349120965
-
TLR cross-talk specifically regulates cytokine production by B cells from chronic inflammatory disease patients
-
Jagannathan M, Hasturk H, Liang Y et al. TLR cross-talk specifically regulates cytokine production by B cells from chronic inflammatory disease patients. J Immunol 2009; 183:7461-70.
-
(2009)
J Immunol
, vol.183
, pp. 7461-7470
-
-
Jagannathan, M.1
Hasturk, H.2
Liang, Y.3
-
51
-
-
68149126174
-
Murine B cell response to TLR7 ligands depends on an IFN-β feedback loop
-
Green NM, Laws A, Kiefer K et al. Murine B cell response to TLR7 ligands depends on an IFN-β feedback loop. J Immunol 2009; 183:1569-76.
-
(2009)
J Immunol
, vol.183
, pp. 1569-1576
-
-
Green, N.M.1
Laws, A.2
Kiefer, K.3
-
52
-
-
36249004377
-
TLR-mediated stimulation of APC: distinct cytokine responses of B cells and dendritic cells
-
Barr TA, Brown S, Ryan G, Zhao J, Gray D. TLR-mediated stimulation of APC: distinct cytokine responses of B cells and dendritic cells. Eur J Immunol 2007; 37:3040-53.
-
(2007)
Eur J Immunol
, vol.37
, pp. 3040-3053
-
-
Barr, T.A.1
Brown, S.2
Ryan, G.3
Zhao, J.4
Gray, D.5
-
53
-
-
42649111367
-
TLR-activated B cells suppress T cell-mediated autoimmunity
-
Lampropoulou V, Hoehlig K, Roch T et al. TLR-activated B cells suppress T cell-mediated autoimmunity. J Immunol 2008; 180:4763-73.
-
(2008)
J Immunol
, vol.180
, pp. 4763-4773
-
-
Lampropoulou, V.1
Hoehlig, K.2
Roch, T.3
-
54
-
-
15244349648
-
TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production
-
Lenert P, Brummel R, Field EH, Ashman RF. TLR-9 activation of marginal zone B cells in lupus mice regulates immunity through increased IL-10 production. J Clin Immunol 2005; 25:29-40.
-
(2005)
J Clin Immunol
, vol.25
, pp. 29-40
-
-
Lenert, P.1
Brummel, R.2
Field, E.H.3
Ashman, R.F.4
-
55
-
-
79957967904
-
CD40 signaling synergizes with TLR-2 in the BCR independent activation of resting B cells
-
Jain S, Chodisetti SB, Agrewala JN. CD40 signaling synergizes with TLR-2 in the BCR independent activation of resting B cells. PLoS ONE 2011; 6:e20651.
-
(2011)
PLoS ONE
, vol.6
-
-
Jain, S.1
Chodisetti, S.B.2
Agrewala, J.N.3
-
56
-
-
80053445138
-
Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells
-
e25542.
-
Boeglin E, Smulski CR, Brun S, Milosevic S, Schneider P, Fournel S. Toll-like receptor agonists synergize with CD40L to induce either proliferation or plasma cell differentiation of mouse B cells. PLoS ONE 2011; 6:e25542.
-
(2011)
PLoS ONE
, vol.6
-
-
Boeglin, E.1
Smulski, C.R.2
Brun, S.3
Milosevic, S.4
Schneider, P.5
Fournel, S.6
-
57
-
-
79953162780
-
Toll-like receptor driven B cell activation in the induction of systemic autoimmunity
-
Green NM, Marshak-Rothstein A. Toll-like receptor driven B cell activation in the induction of systemic autoimmunity. Semin Immunol 2011; 23:106-12.
-
(2011)
Semin Immunol
, vol.23
, pp. 106-112
-
-
Green, N.M.1
Marshak-Rothstein, A.2
-
58
-
-
39549105619
-
B cell autonomous TLR signaling and autoimmunity
-
Meyer-Bahlburg A, Rawlings DJ. B cell autonomous TLR signaling and autoimmunity. Autoimmun Rev 2008; 7:313-6.
-
(2008)
Autoimmun Rev
, vol.7
, pp. 313-316
-
-
Meyer-Bahlburg, A.1
Rawlings, D.J.2
-
59
-
-
0037237628
-
Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation
-
Boonstra A, Asselin-Paturel C, Gilliet M, Crain C, Trinchieri G, Liu YJ, O'Garra A. Flexibility of mouse classical and plasmacytoid-derived dendritic cells in directing T helper type 1 and 2 cell development: dependency on antigen dose and differential toll-like receptor ligation. J Exp Med 2003; 197:101-9.
-
(2003)
J Exp Med
, vol.197
, pp. 101-109
-
-
Boonstra, A.1
Asselin-Paturel, C.2
Gilliet, M.3
Crain, C.4
Trinchieri, G.5
Liu, Y.J.6
O'Garra, A.7
-
60
-
-
27744576801
-
Cell surface recycling of internalized antigen permits dendritic cell priming of B cells
-
Bergtold A, Desai DD, Gavhane A, Clynes R. Cell surface recycling of internalized antigen permits dendritic cell priming of B cells. Immunity 2005; 23:503-14.
-
(2005)
Immunity
, vol.23
, pp. 503-514
-
-
Bergtold, A.1
Desai, D.D.2
Gavhane, A.3
Clynes, R.4
-
61
-
-
78049456523
-
The germinal center reaction
-
quiz 8-9.
-
Gatto D, Brink R. The germinal center reaction. J Allergy Clin Immunol 2010;126:898-907; quiz 8-9.
-
(2010)
J Allergy Clin Immunol
, vol.126
, pp. 898-907
-
-
Gatto, D.1
Brink, R.2
-
62
-
-
44849084239
-
Viruses induce high expression of BAFF by salivary gland epithelial cells through TLR- and type-I IFN-dependent and -independent pathways
-
Ittah M, Miceli-Richard C, Gottenberg JE et al. Viruses induce high expression of BAFF by salivary gland epithelial cells through TLR- and type-I IFN-dependent and -independent pathways. Eur J Immunol 2008; 38:1058-64.
-
(2008)
Eur J Immunol
, vol.38
, pp. 1058-1064
-
-
Ittah, M.1
Miceli-Richard, C.2
Gottenberg, J.E.3
-
63
-
-
32944478316
-
Translating innate immunity into immunological memory: implications for vaccine development
-
Pulendran B, Ahmed R. Translating innate immunity into immunological memory: implications for vaccine development. Cell 2006; 124:849-63.
-
(2006)
Cell
, vol.124
, pp. 849-863
-
-
Pulendran, B.1
Ahmed, R.2
-
64
-
-
33845905223
-
Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling
-
Gavin AL, Hoebe K, Duong B, Ota T, Martin C, Beutler B, Nemazee D. Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling. Science 2006; 314:1936-8.
-
(2006)
Science
, vol.314
, pp. 1936-1938
-
-
Gavin, A.L.1
Hoebe, K.2
Duong, B.3
Ota, T.4
Martin, C.5
Beutler, B.6
Nemazee, D.7
-
65
-
-
37549034962
-
B cell intrinsic TLR signals amplify but are not required for humoral immunity
-
Meyer-Bahlburg A, Khim S, Rawlings DJ. B cell intrinsic TLR signals amplify but are not required for humoral immunity. J Exp Med 2007; 204:3095-101.
-
(2007)
J Exp Med
, vol.204
, pp. 3095-3101
-
-
Meyer-Bahlburg, A.1
Khim, S.2
Rawlings, D.J.3
-
66
-
-
0034775153
-
Toll-like receptors control activation of adaptive immune responses
-
Schnare M, Barton GM, Holt AC, Takeda K, Akira S, Medzhitov R. Toll-like receptors control activation of adaptive immune responses. Nat Immunol 2001; 2:947-50.
-
(2001)
Nat Immunol
, vol.2
, pp. 947-950
-
-
Schnare, M.1
Barton, G.M.2
Holt, A.C.3
Takeda, K.4
Akira, S.5
Medzhitov, R.6
-
67
-
-
27844541797
-
Control of B-cell responses by Toll-like receptors
-
Pasare C, Medzhitov R. Control of B-cell responses by Toll-like receptors. Nature 2005; 438:364-8.
-
(2005)
Nature
, vol.438
, pp. 364-368
-
-
Pasare, C.1
Medzhitov, R.2
-
68
-
-
48749132777
-
Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms
-
Hou B, Reizis B, DeFranco AL. Toll-like receptors activate innate and adaptive immunity by using dendritic cell-intrinsic and -extrinsic mechanisms. Immunity 2008; 29:272-82.
-
(2008)
Immunity
, vol.29
, pp. 272-282
-
-
Hou, B.1
Reizis, B.2
DeFranco, A.L.3
-
69
-
-
79952745936
-
Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response
-
Hou B, Saudan P, Ott G et al. Selective utilization of Toll-like receptor and MyD88 signaling in B cells for enhancement of the antiviral germinal center response. Immunity 2011; 34:375-84.
-
(2011)
Immunity
, vol.34
, pp. 375-384
-
-
Hou, B.1
Saudan, P.2
Ott, G.3
-
70
-
-
33645956556
-
Toll-like receptor stimulation as a third signal required for activation of human naive B cells
-
Ruprecht CR, Lanzavecchia A. Toll-like receptor stimulation as a third signal required for activation of human naive B cells. Eur J Immunol 2006; 36:810-6.
-
(2006)
Eur J Immunol
, vol.36
, pp. 810-816
-
-
Ruprecht, C.R.1
Lanzavecchia, A.2
-
71
-
-
80055080756
-
TLR7 controls the germinal center response to retroviral infection
-
e1002293.
-
Browne EP. TLR7 controls the germinal center response to retroviral infection. PLoS Pathog 2011; 7:e1002293.
-
(2011)
PLoS Pathog
, vol.7
-
-
Browne, E.P.1
-
72
-
-
79952173864
-
Programming the magnitude and persistence of antibody responses with innate immunity
-
Kasturi SP, Skountzou I, Albrecht RA et al. Programming the magnitude and persistence of antibody responses with innate immunity. Nature 2011; 470:543-7.
-
(2011)
Nature
, vol.470
, pp. 543-547
-
-
Kasturi, S.P.1
Skountzou, I.2
Albrecht, R.A.3
-
73
-
-
78650660388
-
TLR ligation triggers somatic hypermutation in transitional B cells inducing the generation of IgM memory B cells
-
Aranburu A, Ceccarelli S, Giorda E, Lasorella R, Ballatore G, Carsetti R. TLR ligation triggers somatic hypermutation in transitional B cells inducing the generation of IgM memory B cells. J Immunol 2010; 185:7293-301.
-
(2010)
J Immunol
, vol.185
, pp. 7293-7301
-
-
Aranburu, A.1
Ceccarelli, S.2
Giorda, E.3
Lasorella, R.4
Ballatore, G.5
Carsetti, R.6
-
74
-
-
77954945284
-
Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation
-
Garin A, Meyer-Hermann M, Contie M et al. Toll-like receptor 4 signaling by follicular dendritic cells is pivotal for germinal center onset and affinity maturation. Immunity 2010; 33:84-95.
-
(2010)
Immunity
, vol.33
, pp. 84-95
-
-
Garin, A.1
Meyer-Hermann, M.2
Contie, M.3
-
75
-
-
77954500603
-
Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner
-
Bessa J, Kopf M, Bachmann MF. Cutting edge: IL-21 and TLR signaling regulate germinal center responses in a B cell-intrinsic manner. J Immunol 2010; 184:4615-9.
-
(2010)
J Immunol
, vol.184
, pp. 4615-4619
-
-
Bessa, J.1
Kopf, M.2
Bachmann, M.F.3
-
76
-
-
79953122463
-
Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88
-
Rahman AH, Zhang R, Blosser CD, Hou B, Defranco AL, Maltzman JS, Wherry EJ, Turka LA. Antiviral memory CD8 T-cell differentiation, maintenance, and secondary expansion occur independently of MyD88. Blood 2011; 117:3123-30.
-
(2011)
Blood
, vol.117
, pp. 3123-3130
-
-
Rahman, A.H.1
Zhang, R.2
Blosser, C.D.3
Hou, B.4
Defranco, A.L.5
Maltzman, J.S.6
Wherry, E.J.7
Turka, L.A.8
-
77
-
-
33750827767
-
Human cytomegalovirus envelope glycoproteins B and H are necessary for TLR2 activation in permissive cells
-
Boehme KW, Guerrero M, Compton T. Human cytomegalovirus envelope glycoproteins B and H are necessary for TLR2 activation in permissive cells. J Immunol 2006; 177:7094-102.
-
(2006)
J Immunol
, vol.177
, pp. 7094-7102
-
-
Boehme, K.W.1
Guerrero, M.2
Compton, T.3
-
78
-
-
0036340341
-
Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling
-
Bieback K, Lien E, Klagge IM et al. Hemagglutinin protein of wild-type measles virus activates toll-like receptor 2 signaling. J Virol 2002; 76:8729-36.
-
(2002)
J Virol
, vol.76
, pp. 8729-8736
-
-
Bieback, K.1
Lien, E.2
Klagge, I.M.3
-
79
-
-
0036829988
-
Cell activation by synthetic lipopeptides of the hepatitis C virus (HCV) - core protein is mediated by toll like receptors (TLRs) 2 and 4
-
Duesberg U, von dem Bussche A, Kirschning C, Miyake K, Sauerbruch T, Spengler U. Cell activation by synthetic lipopeptides of the hepatitis C virus (HCV) - core protein is mediated by toll like receptors (TLRs) 2 and 4. Immunol Lett 2002; 84:89-95.
-
(2002)
Immunol Lett
, vol.84
, pp. 89-95
-
-
Duesberg, U.1
von dem Bussche, A.2
Kirschning, C.3
Miyake, K.4
Sauerbruch, T.5
Spengler, U.6
-
80
-
-
23844455909
-
Cytokine induction by the hepatitis B virus capsid in macrophages is facilitated by membrane heparan sulfate and involves TLR2
-
Cooper A, Tal G, Lider O, Shaul Y. Cytokine induction by the hepatitis B virus capsid in macrophages is facilitated by membrane heparan sulfate and involves TLR2. J Immunol 2005; 175:3165-76.
-
(2005)
J Immunol
, vol.175
, pp. 3165-3176
-
-
Cooper, A.1
Tal, G.2
Lider, O.3
Shaul, Y.4
-
81
-
-
0037061453
-
Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
-
Leadbetter EA, Rifkin IR, Hohlbaum AM, Beaudette BC, Shlomchik MJ, Marshak-Rothstein A. Chromatin-IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors. Nature 2002; 416:603-7.
-
(2002)
Nature
, vol.416
, pp. 603-607
-
-
Leadbetter, E.A.1
Rifkin, I.R.2
Hohlbaum, A.M.3
Beaudette, B.C.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
82
-
-
0347480224
-
Activation of autoreactive B cells by CpG dsDNA
-
Viglianti GA, Lau CM, Hanley TM, Miko BA, Shlomchik MJ, Marshak-Rothstein A. Activation of autoreactive B cells by CpG dsDNA. Immunity 2003; 19:837-47.
-
(2003)
Immunity
, vol.19
, pp. 837-847
-
-
Viglianti, G.A.1
Lau, C.M.2
Hanley, T.M.3
Miko, B.A.4
Shlomchik, M.J.5
Marshak-Rothstein, A.6
-
83
-
-
65249145364
-
Superantigen- and TLR-dependent activation of tonsillar B cells after receptor-mediated endocytosis
-
Jendholm J, Morgelin M, Perez Vidakovics ML, Carlsson M, Leffler H, Cardell LO, Riesbeck K. Superantigen- and TLR-dependent activation of tonsillar B cells after receptor-mediated endocytosis. J Immunol 2009; 182:4713-20.
-
(2009)
J Immunol
, vol.182
, pp. 4713-4720
-
-
Jendholm, J.1
Morgelin, M.2
Perez Vidakovics, M.L.3
Carlsson, M.4
Leffler, H.5
Cardell, L.O.6
Riesbeck, K.7
-
84
-
-
5944247564
-
Fc α/μ receptor mediates endocytosis of IgM-coated microbes
-
Shibuya A, Sakamoto N, Shimizu Y et al. Fc α/μ receptor mediates endocytosis of IgM-coated microbes. Nat Immunol 2000; 1:441-6.
-
(2000)
Nat Immunol
, vol.1
, pp. 441-446
-
-
Shibuya, A.1
Sakamoto, N.2
Shimizu, Y.3
-
85
-
-
33746607379
-
DC-SIGN on B lymphocytes is required for transmission of HIV-1 to T lymphocytes
-
e70.
-
Rappocciolo G, Piazza P, Fuller CL et al. DC-SIGN on B lymphocytes is required for transmission of HIV-1 to T lymphocytes. PLoS Pathog 2006; 2:e70.
-
(2006)
PLoS Pathog
, vol.2
-
-
Rappocciolo, G.1
Piazza, P.2
Fuller, C.L.3
-
86
-
-
33947134377
-
Autophagy-dependent viral recognition by plasmacytoid dendritic cells
-
Lee HK, Lund JM, Ramanathan B, Mizushima N, Iwasaki A. Autophagy-dependent viral recognition by plasmacytoid dendritic cells. Science 2007; 315:1398-401.
-
(2007)
Science
, vol.315
, pp. 1398-1401
-
-
Lee, H.K.1
Lund, J.M.2
Ramanathan, B.3
Mizushima, N.4
Iwasaki, A.5
-
87
-
-
33846937311
-
TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses
-
Heer AK, Shamshiev A, Donda A, Uematsu S, Akira S, Kopf M, Marsland BJ. TLR signaling fine-tunes anti-influenza B cell responses without regulating effector T cell responses. J Immunol 2007; 178:2182-91.
-
(2007)
J Immunol
, vol.178
, pp. 2182-2191
-
-
Heer, A.K.1
Shamshiev, A.2
Donda, A.3
Uematsu, S.4
Akira, S.5
Kopf, M.6
Marsland, B.J.7
-
88
-
-
78649423252
-
MyD88 signaling is indispensable for primary influenza A virus infection but dispensable for secondary infection
-
Seo SU, Kwon HJ, Song JH, Byun YH, Seong BL, Kawai T, Akira S, Kweon MN. MyD88 signaling is indispensable for primary influenza A virus infection but dispensable for secondary infection. J Virol 2010; 84:12713-22.
-
(2010)
J Virol
, vol.84
, pp. 12713-12722
-
-
Seo, S.U.1
Kwon, H.J.2
Song, J.H.3
Byun, Y.H.4
Seong, B.L.5
Kawai, T.6
Akira, S.7
Kweon, M.N.8
-
89
-
-
33646342149
-
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
-
Kato H, Takeuchi O, Sato S et al. Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses. Nature 2006; 441:101-5.
-
(2006)
Nature
, vol.441
, pp. 101-105
-
-
Kato, H.1
Takeuchi, O.2
Sato, S.3
-
90
-
-
38949117752
-
Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination
-
Koyama S, Ishii KJ, Kumar H, Tanimoto T, Coban C, Uematsu S, Kawai T, Akira S. Differential role of TLR- and RLR-signaling in the immune responses to influenza A virus infection and vaccination. J Immunol 2007; 179:4711-20.
-
(2007)
J Immunol
, vol.179
, pp. 4711-4720
-
-
Koyama, S.1
Ishii, K.J.2
Kumar, H.3
Tanimoto, T.4
Coban, C.5
Uematsu, S.6
Kawai, T.7
Akira, S.8
-
91
-
-
80055115679
-
MyD88 plays an essential role in inducing B cells capable of differentiating into antibody-secreting cells after vaccination
-
Kang SM, Yoo DG, Kim MC et al. MyD88 plays an essential role in inducing B cells capable of differentiating into antibody-secreting cells after vaccination. J Virol 2011; 85:11391-400.
-
(2011)
J Virol
, vol.85
, pp. 11391-11400
-
-
Kang, S.M.1
Yoo, D.G.2
Kim, M.C.3
-
92
-
-
52949131887
-
MAVS and MyD88 are essential for innate immunity but not cytotoxic T lymphocyte response against respiratory syncytial virus
-
Bhoj VG, Sun Q, Bhoj EJ et al. MAVS and MyD88 are essential for innate immunity but not cytotoxic T lymphocyte response against respiratory syncytial virus. Proc Natl Acad Sci U S A 2008; 105:14046-51.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 14046-14051
-
-
Bhoj, V.G.1
Sun, Q.2
Bhoj, E.J.3
-
93
-
-
58149336793
-
Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease
-
Delgado MF, Coviello S, Monsalvo AC et al. Lack of antibody affinity maturation due to poor Toll-like receptor stimulation leads to enhanced respiratory syncytial virus disease. Nat Med 2009; 15:34-41.
-
(2009)
Nat Med
, vol.15
, pp. 34-41
-
-
Delgado, M.F.1
Coviello, S.2
Monsalvo, A.C.3
-
94
-
-
33847386349
-
TLR-4 and CD14 polymorphisms in respiratory syncytial virus associated disease
-
Puthothu B, Forster J, Heinzmann A, Krueger M. TLR-4 and CD14 polymorphisms in respiratory syncytial virus associated disease. Dis Markers 2006; 22:303-8.
-
(2006)
Dis Markers
, vol.22
, pp. 303-308
-
-
Puthothu, B.1
Forster, J.2
Heinzmann, A.3
Krueger, M.4
-
95
-
-
34247154497
-
MyD88 is required for the formation of long-term humoral immunity to virus infection
-
Guay HM, Andreyeva TA, Garcea RL, Welsh RM, Szomolanyi-Tsuda E. MyD88 is required for the formation of long-term humoral immunity to virus infection. J Immunol 2007; 178:5124-31.
-
(2007)
J Immunol
, vol.178
, pp. 5124-5131
-
-
Guay, H.M.1
Andreyeva, T.A.2
Garcea, R.L.3
Welsh, R.M.4
Szomolanyi-Tsuda, E.5
-
96
-
-
34548737204
-
MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus
-
Lang KS, Navarini AA, Recher M et al. MyD88 protects from lethal encephalitis during infection with vesicular stomatitis virus. Eur J Immunol 2007; 37:2434-40.
-
(2007)
Eur J Immunol
, vol.37
, pp. 2434-2440
-
-
Lang, K.S.1
Navarini, A.A.2
Recher, M.3
-
97
-
-
63149198344
-
Vesicular stomatitis virus M protein mutant stimulates maturation of Toll-like receptor 7 (TLR7)-positive dendritic cells through TLR-dependent and -independent mechanisms
-
Ahmed M, Mitchell LM, Puckett S, Brzoza-Lewis KL, Lyles DS, Hiltbold EM. Vesicular stomatitis virus M protein mutant stimulates maturation of Toll-like receptor 7 (TLR7)-positive dendritic cells through TLR-dependent and -independent mechanisms. J Virol 2009; 83:2962-75.
-
(2009)
J Virol
, vol.83
, pp. 2962-2975
-
-
Ahmed, M.1
Mitchell, L.M.2
Puckett, S.3
Brzoza-Lewis, K.L.4
Lyles, D.S.5
Hiltbold, E.M.6
-
98
-
-
34247577195
-
Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway
-
Georgel P, Jiang Z, Kunz S et al. Vesicular stomatitis virus glycoprotein G activates a specific antiviral Toll-like receptor 4-dependent pathway. Virology 2007; 362:304-13.
-
(2007)
Virology
, vol.362
, pp. 304-313
-
-
Georgel, P.1
Jiang, Z.2
Kunz, S.3
-
99
-
-
34547102725
-
Epstein-Barr virus induces MCP-1 secretion by human monocytes via TLR2
-
Gaudreault E, Fiola S, Olivier M, Gosselin J. Epstein-Barr virus induces MCP-1 secretion by human monocytes via TLR2. J Virol 2007; 81:8016-24.
-
(2007)
J Virol
, vol.81
, pp. 8016-8024
-
-
Gaudreault, E.1
Fiola, S.2
Olivier, M.3
Gosselin, J.4
-
100
-
-
33751206873
-
Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells
-
Sato A, Linehan MM, Iwasaki A. Dual recognition of herpes simplex viruses by TLR2 and TLR9 in dendritic cells. Proc Natl Acad Sci U S A 2006; 103:17343-8.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 17343-17348
-
-
Sato, A.1
Linehan, M.M.2
Iwasaki, A.3
-
101
-
-
12144286763
-
Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection
-
Tabeta K, Georgel P, Janssen E et al. Toll-like receptors 9 and 3 as essential components of innate immune defense against mouse cytomegalovirus infection. Proc Natl Acad Sci U S A 2004; 101:3516-21.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3516-3521
-
-
Tabeta, K.1
Georgel, P.2
Janssen, E.3
-
102
-
-
27744451943
-
MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-α release and initiation of immune responses in vivo
-
Delale T, Paquin A, Asselin-Paturel C et al. MyD88-dependent and -independent murine cytomegalovirus sensing for IFN-α release and initiation of immune responses in vivo. J Immunol 2005; 175:6723-32.
-
(2005)
J Immunol
, vol.175
, pp. 6723-6732
-
-
Delale, T.1
Paquin, A.2
Asselin-Paturel, C.3
-
103
-
-
41949132774
-
Role for MyD88 signaling in murine γ herpesvirus 68 latency
-
Gargano LM, Moser JM, Speck SH. Role for MyD88 signaling in murine γ herpesvirus 68 latency. J Virol 2008; 82:3853-63.
-
(2008)
J Virol
, vol.82
, pp. 3853-3863
-
-
Gargano, L.M.1
Moser, J.M.2
Speck, S.H.3
-
104
-
-
1842588698
-
Development of a human adaptive immune system in cord blood cell-transplanted mice
-
Traggiai E, Chicha L, Mazzucchelli L, Bronz L, Piffaretti JC, Lanzavecchia A, Manz MG. Development of a human adaptive immune system in cord blood cell-transplanted mice. Science 2004; 304:104-7.
-
(2004)
Science
, vol.304
, pp. 104-107
-
-
Traggiai, E.1
Chicha, L.2
Mazzucchelli, L.3
Bronz, L.4
Piffaretti, J.C.5
Lanzavecchia, A.6
Manz, M.G.7
-
105
-
-
70350464959
-
Toll-like receptor 7-induced immune response to cutaneous West Nile virus infection
-
Welte T, Reagan K, Fang H et al. Toll-like receptor 7-induced immune response to cutaneous West Nile virus infection. J Gen Virol 2009; 90(Pt 11):2660-8.
-
(2009)
J Gen Virol
, vol.90
, Issue.PART 11
, pp. 2660-2668
-
-
Welte, T.1
Reagan, K.2
Fang, H.3
-
106
-
-
11144273976
-
Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis
-
Wang T, Town T, Alexopoulou L, Anderson JF, Fikrig E, Flavell RA. Toll-like receptor 3 mediates West Nile virus entry into the brain causing lethal encephalitis. Nat Med 2004; 10:1366-73.
-
(2004)
Nat Med
, vol.10
, pp. 1366-1373
-
-
Wang, T.1
Town, T.2
Alexopoulou, L.3
Anderson, J.F.4
Fikrig, E.5
Flavell, R.A.6
-
107
-
-
78049494595
-
The innate immune adaptor molecule MyD88 restricts West Nile virus replication and spread in neurons of the central nervous system
-
Szretter KJ, Daffis S, Patel J, Suthar MS, Klein RS, Gale M Jr, Diamond MS. The innate immune adaptor molecule MyD88 restricts West Nile virus replication and spread in neurons of the central nervous system. J Virol 2010; 84:12125-38.
-
(2010)
J Virol
, vol.84
, pp. 12125-12138
-
-
Szretter, K.J.1
Daffis, S.2
Patel, J.3
Suthar, M.S.4
Klein, R.S.5
Gale Jr., M.6
Diamond, M.S.7
-
108
-
-
79955784340
-
Decreased dengue replication and an increased anti-viral humoral response with the use of combined Toll-like receptor 3 and 7/8 agonists in macaques
-
e19323.
-
Sariol CA, Martinez MI, Rivera F et al. Decreased dengue replication and an increased anti-viral humoral response with the use of combined Toll-like receptor 3 and 7/8 agonists in macaques. PLoS ONE 2011; 6:e19323.
-
(2011)
PLoS ONE
, vol.6
-
-
Sariol, C.A.1
Martinez, M.I.2
Rivera, F.3
-
109
-
-
0037069682
-
HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites
-
Kwong PD, Doyle ML, Casper DJ et al. HIV-1 evades antibody-mediated neutralization through conformational masking of receptor-binding sites. Nature 2002; 420:678-82.
-
(2002)
Nature
, vol.420
, pp. 678-682
-
-
Kwong, P.D.1
Doyle, M.L.2
Casper, D.J.3
-
111
-
-
79960466171
-
Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry
-
Kane M, Case LK, Wang C, Yurkovetskiy L, Dikiy S, Golovkina TV. Innate immune sensing of retroviral infection via Toll-like receptor 7 occurs upon viral entry. Immunity 2011; 35:135-45.
-
(2011)
Immunity
, vol.35
, pp. 135-145
-
-
Kane, M.1
Case, L.K.2
Wang, C.3
Yurkovetskiy, L.4
Dikiy, S.5
Golovkina, T.V.6
-
112
-
-
61449084631
-
Myd88 is required for an antibody response to retroviral infection
-
e1000298.
-
Browne EP, Littman DR. Myd88 is required for an antibody response to retroviral infection. PLoS Pathog 2009; 5:e1000298.
-
(2009)
PLoS Pathog
, vol.5
-
-
Browne, E.P.1
Littman, D.R.2
-
113
-
-
80054115012
-
Successful transmission of a retrovirus depends on the commensal microbiota
-
Kane M, Case LK, Kopaskie K, Kozlova A, MacDearmid C, Chervonsky AV, Golovkina TV. Successful transmission of a retrovirus depends on the commensal microbiota. Science 2011; 334:245-9.
-
(2011)
Science
, vol.334
, pp. 245-249
-
-
Kane, M.1
Case, L.K.2
Kopaskie, K.3
Kozlova, A.4
MacDearmid, C.5
Chervonsky, A.V.6
Golovkina, T.V.7
-
114
-
-
0037133308
-
Murine retroviruses activate B cells via interaction with toll-like receptor 4
-
Rassa JC, Meyers JL, Zhang Y, Kudaravalli R, Ross SR. Murine retroviruses activate B cells via interaction with toll-like receptor 4. Proc Natl Acad Sci U S A 2002; 99:2281-6.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 2281-2286
-
-
Rassa, J.C.1
Meyers, J.L.2
Zhang, Y.3
Kudaravalli, R.4
Ross, S.R.5
-
115
-
-
0141998606
-
Molecular identification of a danger signal that alerts the immune system to dying cells
-
Shi Y, Evans JE, Rock KL. Molecular identification of a danger signal that alerts the immune system to dying cells. Nature 2003; 425:516-21.
-
(2003)
Nature
, vol.425
, pp. 516-521
-
-
Shi, Y.1
Evans, J.E.2
Rock, K.L.3
-
116
-
-
0037471003
-
Pyogenic bacterial infections in humans with IRAK-4 deficiency
-
Picard C, Puel A, Bonnet M et al. Pyogenic bacterial infections in humans with IRAK-4 deficiency. Science 2003; 299:2076-9.
-
(2003)
Science
, vol.299
, pp. 2076-2079
-
-
Picard, C.1
Puel, A.2
Bonnet, M.3
-
117
-
-
48749109290
-
Pyogenic bacterial infections in humans with MyD88 deficiency
-
von BernuthH, Picard C, Jin Z et al. Pyogenic bacterial infections in humans with MyD88 deficiency. Science 2008; 321:691-6.
-
(2008)
Science
, vol.321
, pp. 691-696
-
-
von, B.1
Picard, C.2
Jin, Z.3
-
118
-
-
34948904198
-
Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity
-
Ku CL, von Bernuth H, Picard C et al. Selective predisposition to bacterial infections in IRAK-4-deficient children: IRAK-4-dependent TLRs are otherwise redundant in protective immunity. J Exp Med 2007; 204:2407-22.
-
(2007)
J Exp Med
, vol.204
, pp. 2407-2422
-
-
Ku, C.L.1
von Bernuth, H.2
Picard, C.3
-
119
-
-
34548699323
-
TLR3 deficiency in patients with herpes simplex encephalitis
-
Zhang SY, Jouanguy E, Ugolini S et al. TLR3 deficiency in patients with herpes simplex encephalitis. Science 2007; 317:1522-7.
-
(2007)
Science
, vol.317
, pp. 1522-1527
-
-
Zhang, S.Y.1
Jouanguy, E.2
Ugolini, S.3
-
120
-
-
80555144890
-
Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity
-
Guo Y, Audry M, Ciancanelli M et al. Herpes simplex virus encephalitis in a patient with complete TLR3 deficiency: TLR3 is otherwise redundant in protective immunity. J Exp Med 2011; 208:2083-98.
-
(2011)
J Exp Med
, vol.208
, pp. 2083-2098
-
-
Guo, Y.1
Audry, M.2
Ciancanelli, M.3
-
121
-
-
55349142293
-
IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans
-
Isnardi I, Ng YS, Srdanovic I et al. IRAK-4- and MyD88-dependent pathways are essential for the removal of developing autoreactive B cells in humans. Immunity 2008; 29:746-57.
-
(2008)
Immunity
, vol.29
, pp. 746-757
-
-
Isnardi, I.1
Ng, Y.S.2
Srdanovic, I.3
-
122
-
-
80053132436
-
Broad neutralization coverage of HIV by multiple highly potent antibodies
-
Walker LM, Huber M, Doores KJ et al. Broad neutralization coverage of HIV by multiple highly potent antibodies. Nature 2011; 477:466-70.
-
(2011)
Nature
, vol.477
, pp. 466-470
-
-
Walker, L.M.1
Huber, M.2
Doores, K.J.3
|