CpG DNA induces IgG class switch DNA recombination by activating human B cells through an innate pathway that requires TLR9 and cooperates with IL-10

Journal of Immunology

Volumn 173, Issue 7, 2004, Pages 4479-4491

  He, Bing ^a   Qiao, Xugang ^a   Cerutti, Andrea ^a,b  

^a WEILL CORNELL MEDICAL COLLEGE   (United States)

^b Weill Graduate School of Medical Sciences of Cornell University   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; B LYMPHOCYTE RECEPTOR; CYTIDINE DEAMINASE; CYTOKINE; DNA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G; IMMUNOGLOBULIN M; INTERFERON REGULATORY FACTOR 4; INTERLEUKIN 10; STAT PROTEIN; STAT1 PROTEIN; STAT3 PROTEIN; TOLL LIKE RECEPTOR; TOLL LIKE RECEPTOR 9; TRANSCRIPTION FACTOR REL; TUMOR NECROSIS FACTOR;

ARTICLE; AUTOIMMUNE DISEASE; B LYMPHOCYTE; CONTROLLED STUDY; CPG ISLAND; DNA RECOMBINATION; ENZYME LINKED IMMUNOSORBENT ASSAY; FLOW CYTOMETRY; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; IMMUNE RESPONSE; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; RHEUMATOID ARTHRITIS; SOUTHERN BLOTTING; SYSTEMIC LUPUS ERYTHEMATOSUS;

EID: 4644241216     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.173.7.4479     Document Type: Article

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