Viral double-stranded RNA triggers Ig class switching by activating upper respiratory mucosa B cells through an innate TLR3 pathway involving BAFF

Journal of Immunology

Volumn 181, Issue 1, 2008, Pages 276-287

  Xu, Weifeng ^a   Santini, Paul A ^a,b   Matthews, Allysia J ^a,c   Chiu, April ^a   Plebani, Alessandro ^d   He, Bing ^a   Chen, Kang ^c   Cerutti, Andrea ^a,c,e  

^a Department of Pathology and Laboratory Medicine ^*  (United States)

^b Cell and Molecular Biology Allied Program

^c Weill Cornell Graduate School of Biomedical Sciences   (United States)

^d UNIVERSITY OF BRESCIA   (Italy)

^e WEILL CORNELL MEDICAL COLLEGE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

B CELL ACTIVATING FACTOR; CD40 ANTIGEN; DOUBLE STRANDED RNA; IMMUNOGLOBULIN A; IMMUNOGLOBULIN CLASS; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; IMMUNOGLOBULIN G; LYMPHOCYTE ANTIGEN RECEPTOR; TOLL LIKE RECEPTOR 3; TOLL LIKE RECEPTOR ADAPTOR MOLECULE 1; VIRUS RNA; AICDA (ACTIVATION INDUCED CYTIDINE DEAMINASE); AICDA (ACTIVATION-INDUCED CYTIDINE DEAMINASE); CYTIDINE DEAMINASE; IMMUNOGLOBULIN; TICAM1 PROTEIN, HUMAN; TLR3 PROTEIN, HUMAN; VESICULAR TRANSPORT ADAPTOR PROTEIN;

ARTICLE; B LYMPHOCYTE; GENE REARRANGEMENT; GENETIC RECOMBINATION; GENETIC TRANSCRIPTION; IMMUNOGLOBULIN PRODUCTION; INNATE IMMUNITY; PRIORITY JOURNAL; RESPIRATORY TRACT MUCOSA; UPPER RESPIRATORY TRACT; VIRUS INFECTION; CELL CULTURE; CELL PROLIFERATION; CYTOLOGY; DENDRITIC CELL; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MUCOSA; SIGNAL TRANSDUCTION; UPREGULATION;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; ANTIGENS, CD40; B-CELL ACTIVATING FACTOR; B-LYMPHOCYTES; CELL PROLIFERATION; CELLS, CULTURED; CYTIDINE DEAMINASE; DENDRITIC CELLS; HUMANS; IMMUNOGLOBULIN CLASS SWITCHING; IMMUNOGLOBULINS; MUCOUS MEMBRANE; RNA, DOUBLE-STRANDED; SIGNAL TRANSDUCTION; TOLL-LIKE RECEPTOR 3; UP-REGULATION;

EID: 47949102460     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.1.276     Document Type: Article

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