The innate immune adaptor molecule MyD88 restricts west nile virus replication and spread in neurons of the central nervous system

Journal of Virology

Volumn 84, Issue 23, 2010, Pages 12125-12138

  Szretter, Kristy J ^a   Daffis, Stephane ^a   Patel, Jigisha ^a   Suthar, Mehul S ^b   Klein, Robyn S ^a   Gale Jr , Michael ^b   Diamond, Michael S ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF WASHINGTON SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA INTERFERON; BETA INTERFERON; CXCL9 CHEMOKINE; GAMMA INTERFERON INDUCIBLE PROTEIN 10; INTERFERON REGULATORY FACTOR 7; MYELOID DIFFERENTIATION FACTOR 88; RETINOIC ACID INDUCIBLE PROTEIN I; TOLL LIKE RECEPTOR 3;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; B LYMPHOCYTE; BRAIN REGION; CELLULAR IMMUNITY; CENTRAL NERVOUS SYSTEM; CENTRAL NERVOUS SYSTEM INFECTION; CONTROLLED STUDY; CYTOKINE PRODUCTION; FLAVIVIRUS INFECTION; HUMORAL IMMUNITY; INNATE IMMUNITY; LEUKOCYTE MIGRATION; MACROPHAGE; MONOCYTE; MOUSE; MYELOID DENDRITIC CELL; NERVE CELL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; SURVIVAL; T LYMPHOCYTE; VIRUS PATHOGENESIS; VIRUS REPLICATION; VIRUS VIRULENCE; WEST NILE FLAVIVIRUS;

ANIMALS; CD8-POSITIVE T-LYMPHOCYTES; CENTRAL NERVOUS SYSTEM; CHEMOKINES; DNA PRIMERS; GENE EXPRESSION REGULATION; IMMUNOHISTOCHEMISTRY; INTERFERON TYPE I; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; MYELOID DIFFERENTIATION FACTOR 88; NEURONS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STATISTICS, NONPARAMETRIC; VIRUS REPLICATION; WEST NILE FEVER; WEST NILE VIRUS;

MUS; WEST NILE VIRUS;

EID: 78049494595     PISSN: 0022538X     EISSN: 10985514     Source Type: Journal    
DOI: 10.1128/JVI.01026-10     Document Type: Article

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