메뉴 건너뛰기




Volumn 8, Issue 3, 2012, Pages 183-192

Resistance to type 2 diabetes mellitus: A matter of hormesis?

Author keywords

[No Author keywords available]

Indexed keywords

INSULIN;

EID: 84862742993     PISSN: 17595029     EISSN: 17595037     Source Type: Journal    
DOI: 10.1038/nrendo.2011.158     Document Type: Article
Times cited : (70)

References (131)
  • 1
    • 72449150103 scopus 로고    scopus 로고
    • The global diabetes epidemic as a consequence of lifestyle- induced low-grade inflammation
    • Kolb, H. and Mandrup-Poulsen, T The global diabetes epidemic as a consequence of lifestyle- induced low-grade inflammation. Diabetologia 53, 10-20 (2010).
    • (2010) Diabetologia , vol.53 , pp. 10-20
    • Kolb, H.1    Mandrup-Poulsen, T.2
  • 2
    • 0031710787 scopus 로고    scopus 로고
    • Prevalence of insulin resistance in metabolic disorders: The Bruneck study
    • Bonora, E. et al. Prevalence of insulin resistance in metabolic disorders: the Bruneck study. Diabetes 47, 1643-1649 (1998).
    • (1998) Diabetes , vol.47 , pp. 1643-1649
    • Bonora, E.1
  • 3
    • 0030884698 scopus 로고    scopus 로고
    • European Group for the Study of Insulin Resistance (EGIR)
    • Ferrannini, E. et al. European Group for the Study of Insulin Resistance (EGIR). J. Clin. Invest. 100, 1166-1173 (1997).
    • (1997) J. Clin. Invest , vol.100 , pp. 1166-1173
    • Ferrannini, E.1
  • 4
    • 79960226240 scopus 로고    scopus 로고
    • Characterizing the profile of obese patients who are metabolically healthy
    • Primeau, V et al. Characterizing the profile of obese patients who are metabolically healthy. Int. J. Obes. (Lond.) 35, 971-981 (2011).
    • (2011) Int. J. Obes. (Lond.) , vol.35 , pp. 971-981
    • Primeau, V.1
  • 7
    • 79951694160 scopus 로고    scopus 로고
    • Prevalence, metabolic features, and prognosis of metabolically healthy obese Italian individuals: The Cremona study
    • Calori, G. et al. Prevalence, metabolic features, and prognosis of metabolically healthy obese Italian individuals: the Cremona study. Diabetes Care 34, 210-215 (2011).
    • (2011) Diabetes Care , vol.34 , pp. 210-215
    • Calori, G.1
  • 8
    • 33644749322 scopus 로고    scopus 로고
    • Mechanisms of pancreatic (3-cell death in type 1 and type 2 diabetes: Many differences, few similarities
    • Cnop, M. et al. Mechanisms of pancreatic 3-cell death in type 1 and type 2 diabetes: many differences, few similarities. Diabetes 54 (Suppl. 2), 97-107 (2005).
    • (2005) Diabetes , vol.54 , pp. 97-107
    • Cnop, M.1
  • 9
    • 53549094111 scopus 로고    scopus 로고
    • Relationship between 3-cell mass and diabetes onset. Diabetes. Obes
    • Matveyenko, A. V. and Butler, P C. Relationship between 3-cell mass and diabetes onset. Diabetes. Obes. Metab. 10 (Suppl. 4), 23-31 (2008).
    • (2008) Metab , vol.10 , pp. 23-31
    • Matveyenko, A.V.1    Butler, P.C.2
  • 10
    • 79151478555 scopus 로고    scopus 로고
    • Type 2 diabetes as an inflammatory disease
    • Donath, M. Y and Shoelson, S. E. Type 2 diabetes as an inflammatory disease. Nat. Rev. Immunol. 11, 98-107 (2011).
    • (2011) Nat. Rev. Immunol , vol.11 , pp. 98-107
    • Donath, M.Y.1    Shoelson, S.E.2
  • 11
    • 43849111166 scopus 로고    scopus 로고
    • The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: A 20-year follow-up study
    • Li, G. et al. The long-term effect of lifestyle interventions to prevent diabetes in the China Da Qing Diabetes Prevention Study: a 20-year follow-up study. Lancet 371, 1783-1789 (2008).
    • (2008) Lancet , vol.371 , pp. 1783-1789
    • Li, G.1
  • 12
    • 70449517253 scopus 로고    scopus 로고
    • 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study
    • Diabetes Prevention Program Research Group. 10-year follow-up of diabetes incidence and weight loss in the Diabetes Prevention Program Outcomes Study. Lancet 374, 1677-1686 (2009)
    • (2009) Lancet , vol.374 , pp. 1677-1686
  • 13
    • 34250844410 scopus 로고    scopus 로고
    • Biological stress response terminology: Integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol. Appl
    • Calabrese, E. J. et al. Biological stress response terminology: integrating the concepts of adaptive response and preconditioning stress within a hormetic dose-response framework. Toxicol. Appl. Pharmacol. 222, 122-128 (2007).
    • (2007) Pharmacol , vol.222 , pp. 122-128
    • Calabrese, E.J.1
  • 14
    • 0034455878 scopus 로고    scopus 로고
    • Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes
    • Mohanty, P et al. Glucose challenge stimulates reactive oxygen species (ROS) generation by leucocytes. J. Clin. Endocrinol. Metab. 85, 2970-2973 (2000).
    • (2000) J. Clin. Endocrinol. Metab , vol.85 , pp. 2970-2973
    • Mohanty, P.1
  • 15
    • 0037109184 scopus 로고    scopus 로고
    • Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: Role of oxidative stress
    • Esposito, K. et al. Inflammatory cytokine concentrations are acutely increased by hyperglycemia in humans: role of oxidative stress. Circulation 106, 2067-2072 (2002).
    • (2002) Circulation , vol.106 , pp. 2067-2072
    • Esposito, K.1
  • 16
    • 0642307072 scopus 로고    scopus 로고
    • Meal modulation of circulating interleukin 18 and adiponectin concentrations in healthy subjects and in patients with type 2 diabetes mellitus
    • Esposito, K. et al. Meal modulation of circulating interleukin 18 and adiponectin concentrations in healthy subjects and in patients with type 2 diabetes mellitus. Am. J. Clin. Nutr. 78, 1135-1140 (2003).
    • (2003) Am. J. Clin. Nutr , vol.78 , pp. 1135-1140
    • Esposito, K.1
  • 17
    • 2142827887 scopus 로고    scopus 로고
    • Increase in intranuclear nuclear factor kB and decrease in inhibitor kB in mononuclear cells after a mixed meal: Evidence for a proinflammatory effect
    • Aljada, A. et al. Increase in intranuclear nuclear factor kB and decrease in inhibitor kB in mononuclear cells after a mixed meal: evidence for a proinflammatory effect. Am. J. Clin. Nutr. 79, 682-690 (2004).
    • (2004) Am. J. Clin. Nutr , vol.79 , pp. 682-690
    • Aljada, A.1
  • 18
    • 5444256832 scopus 로고    scopus 로고
    • Activation of leukocytes by postprandial lipemia in healthy volunteers
    • van Oostrom, A. J. et al. Activation of leukocytes by postprandial lipemia in healthy volunteers. Atherosclerosis 177, 175-182 (2004).
    • (2004) Atherosclerosis , vol.177 , pp. 175-182
    • Van Oostrom, A.J.1
  • 19
    • 43849102129 scopus 로고    scopus 로고
    • High-fat, energy-dense, fast-food-style breakfast results in an increase in oxidative stress in metabolic syndrome
    • Devaraj, S., Wang-Polagruto, J., Polagruto, J., Keen, C. L. and Jialal, I. High-fat, energy-dense, fast-food-style breakfast results in an increase in oxidative stress in metabolic syndrome. Metabolism 57, 867-870 (2008).
    • (2008) Metabolism , vol.57 , pp. 867-870
    • Devaraj, S.1    Wang-Polagruto, J.2    Polagruto, J.3    Keen, C.L.4    Jialal, I.5
  • 20
    • 43549113382 scopus 로고    scopus 로고
    • High-glycemic index carbohydrate increases nuclear factor-KB activation in mononuclear cells of young, lean healthy subjects
    • Dickinson, S., Hancock, D. P., Petocz, P., Ceriello, A., Brand-Miller, J. High-glycemic index carbohydrate increases nuclear factor-KB activation in mononuclear cells of young, lean healthy subjects. Am. J. Clin. Nutr. 87, 1188-1193 (2008).
    • (2008) Am. J. Clin. Nutr , vol.87 , pp. 1188-1193
    • Dickinson, S.1    Hancock, D.P.2    Petocz, P.3    Ceriello, A.4    Brand-Miller, J.5
  • 21
    • 48749128643 scopus 로고    scopus 로고
    • Structures of the Toll-like receptor family and its ligand complexes
    • Jin, M. S. and Lee, J. O. Structures of the Toll-like receptor family and its ligand complexes. Immunity 29, 182-191 (2008).
    • (2008) Immunity , vol.29 , pp. 182-191
    • Jin, M.S.1    Lee, J.O.2
  • 22
    • 17844391306 scopus 로고    scopus 로고
    • Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4
    • Weatherill, A. R. et al. Saturated and polyunsaturated fatty acids reciprocally modulate dendritic cell functions mediated through TLR4. J. Immunol. 174, 5390-5397 (2005).
    • (2005) J. Immunol , vol.174 , pp. 5390-5397
    • Weatherill, A.R.1
  • 23
    • 33750584214 scopus 로고    scopus 로고
    • TLR4 links innate immunity and fatty acid-induced insulin resistance
    • Shi, H. et al. TLR4 links innate immunity and fatty acid-induced insulin resistance. J. Clin. Invest. 116, 3015-3025 (2006).
    • (2006) J. Clin. Invest , vol.116 , pp. 3015-3025
    • Shi, H.1
  • 24
    • 58149310977 scopus 로고    scopus 로고
    • Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-KB pathway in adipocytes links nutritional signalling with innate immunity
    • Schaeffler, A. et al. Fatty acid-induced induction of Toll-like receptor-4/nuclear factor-KB pathway in adipocytes links nutritional signalling with innate immunity. Immunology 126, 233-245 (2009).
    • (2009) Immunology , vol.126 , pp. 233-245
    • Schaeffler, A.1
  • 25
    • 77950888339 scopus 로고    scopus 로고
    • Nutrient modification of the innate immune response: A novel mechanism by which saturated fatty acids greatly amplify monocyte inflammation. Arterioscler. Thromb. Vasc
    • Schwartz, E. A. et al. Nutrient modification of the innate immune response: a novel mechanism by which saturated fatty acids greatly amplify monocyte inflammation. Arterioscler. Thromb. Vasc. Biol. 30, 802-808 (2010).
    • (2010) Biol , vol.30 , pp. 802-808
    • Schwartz, E.A.1
  • 26
    • 33745945755 scopus 로고    scopus 로고
    • Tolerance to microbial TLR ligands: Molecular mechanisms and relevance to disease
    • Medvedev, A. E., Sabroe, I., Hasday, J. D. and Vogel, S. N. Tolerance to microbial TLR ligands: molecular mechanisms and relevance to disease. J. Endotoxin. Res. 12, 133-150 (2006).
    • (2006) J. Endotoxin. Res , vol.12 , pp. 133-150
    • Medvedev, A.E.1    Sabroe, I.2    Hasday, J.D.3    Vogel, S.N.4
  • 27
    • 35748984420 scopus 로고    scopus 로고
    • Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance
    • Biswas, S. K. et al. Role for MyD88-independent, TRIF pathway in lipid A/TLR4-induced endotoxin tolerance. J. Immunol. 179, 4083-4092 (2007).
    • (2007) J. Immunol , vol.179 , pp. 4083-4092
    • Biswas, S.K.1
  • 28
    • 70349650125 scopus 로고    scopus 로고
    • Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-p-dependent pathways and increases expression of negative regulators of TLR signaling
    • Piao, W. et al. Endotoxin tolerance dysregulates MyD88- and Toll/IL-1R domain-containing adapter inducing IFN-p-dependent pathways and increases expression of negative regulators of TLR signaling. J. Leukoc. Biol. 86, 863-875 (2009).
    • (2009) J. Leukoc. Biol , vol.86 , pp. 863-875
    • Piao, W.1
  • 29
    • 78650671081 scopus 로고    scopus 로고
    • Inhibition of TLR4-induced IKB kinase activity by the RON receptor tyrosine kinase and its ligand, macrophage-stimulating protein
    • Ray, M. et al. Inhibition of TLR4-induced IKB kinase activity by the RON receptor tyrosine kinase and its ligand, macrophage-stimulating protein. J. Immunol. 185, 7309-7316 (2010).
    • (2010) J. Immunol , vol.185 , pp. 7309-7316
    • Ray, M.1
  • 30
    • 50449086746 scopus 로고    scopus 로고
    • Obesity and free fatty acids. Endocrinol
    • Boden, G. Obesity and free fatty acids. Endocrinol. Metab. Clin. North Am. 37, 635-646 (2008).
    • (2008) Metab. Clin. North Am , vol.37 , pp. 635-646
    • Boden, G.1
  • 31
    • 58149333718 scopus 로고    scopus 로고
    • High glucose induces Toll-like receptor expression in human monocytes: Mechanism of activation
    • Dasu, M. R., Devaraj, S., Zhao, L., Hwang, D. H. and Jialal, I. High glucose induces Toll-like receptor expression in human monocytes: mechanism of activation. Diabetes 57, 3090-3098 (2008).
    • (2008) Diabetes , vol.57 , pp. 3090-3098
    • Dasu, M.R.1    Devaraj, S.2    Zhao, L.3    Hwang, D.H.4    Jialal, I.5
  • 32
    • 33644757817 scopus 로고    scopus 로고
    • Natural antibiotics and insulin sensitivity: The role of bactericidal/permeability- increasing protein
    • Gubern, C. et al. Natural antibiotics and insulin sensitivity: the role of bactericidal/permeability- increasing protein. Diabetes 55, 216-224 (2006).
    • (2006) Diabetes , vol.55 , pp. 216-224
    • Gubern, C.1
  • 33
    • 33947182436 scopus 로고    scopus 로고
    • Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes
    • Creely, S. J. et al. Lipopolysaccharide activates an innate immune system response in human adipose tissue in obesity and type 2 diabetes. Am. J. Physiol. Endocrinol. Metab. 292, E740-E747 (2007).
    • (2007) Am. J. Physiol. Endocrinol. Metab , vol.292 , pp. E740-E747
    • Creely, S.J.1
  • 34
    • 77950419928 scopus 로고    scopus 로고
    • Elevated endotoxin levels in non-alcoholic fatty liver disease
    • Harte, A. L. et al. Elevated endotoxin levels in non-alcoholic fatty liver disease. J. Inflamm. (Lond.) 7, 15 (2010).
    • (2010) J. Inflamm. (Lond.) , vol.7 , pp. 15
    • Harte, A.L.1
  • 35
    • 77953060025 scopus 로고    scopus 로고
    • Increased Toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects
    • Dasu, M. R., Devaraj, S., Park, S. and Jialal, I. Increased Toll-like receptor (TLR) activation and TLR ligands in recently diagnosed type 2 diabetic subjects. Diabetes Care 33, 861-868 (2010).
    • (2010) Diabetes Care , vol.33 , pp. 861-868
    • Dasu, M.R.1    Devaraj, S.2    Park, S.3    Jialal, I.4
  • 36
    • 34848815899 scopus 로고    scopus 로고
    • Different TNFa expression elicited by glucose in monocytes from type 2 diabetes mellitus patients
    • Chacón, M. R. et al. Different TNFa expression elicited by glucose in monocytes from type 2 diabetes mellitus patients. Atherosclerosis 194, 18-25 (2007).
    • (2007) Atherosclerosis , vol.194 , pp. 18-25
    • Chacón, M.R.1
  • 37
    • 77955273068 scopus 로고    scopus 로고
    • Y High interleukin-12 production from stimulated peripheral blood mononuclear cells of type 2 diabetes patients
    • Wu, H. P, Kuo, S. F., Wu, S. Y and Chuang, D. Y High interleukin-12 production from stimulated peripheral blood mononuclear cells of type 2 diabetes patients. Cytokine 51, 298-304 (2010)
    • (2010) Cytokine , vol.51 , pp. 298-304
    • Wu, H.P.1    Kuo, S.F.2    Wu, S.Y.3    Chuang, D.4
  • 38
    • 79958248856 scopus 로고    scopus 로고
    • Type 2 diabetes and lipoprotein metabolism affect LPS-induced cytokine and chemokine release in primary human monocytes
    • Bala, M. et al. Type 2 diabetes and lipoprotein metabolism affect LPS-induced cytokine and chemokine release in primary human monocytes. Exp. Clin. Endocrinol. Diabetes 119, 370-376 (2011).
    • (2011) Exp. Clin. Endocrinol. Diabetes , vol.119 , pp. 370-376
    • Bala, M.1
  • 39
    • 58149359307 scopus 로고    scopus 로고
    • Elevated Toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects
    • Reyna, S. M. et al. Elevated Toll-like receptor 4 expression and signaling in muscle from insulin-resistant subjects. Diabetes 57, 2595-2602 (2008).
    • (2008) Diabetes , vol.57 , pp. 2595-2602
    • Reyna, S.M.1
  • 40
    • 0036224269 scopus 로고    scopus 로고
    • Low production capacity of interleukin-10 associates with the metabolic syndrome and type 2 diabetes: The Leiden 85- Plus Study
    • van Exel, E. et al. Low production capacity of interleukin-10 associates with the metabolic syndrome and type 2 diabetes: the Leiden 85- Plus Study. Diabetes 51, 1088-1092 (2002).
    • (2002) Diabetes , vol.51 , pp. 1088-1092
    • Van Exel, E.1
  • 41
    • 78650773537 scopus 로고    scopus 로고
    • Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors
    • Dasu, M. R., Jialal, I. Free fatty acids in the presence of high glucose amplify monocyte inflammation via Toll-like receptors. Am. J. Physiol. Endocrinol. Metab. 300, 145-154 (2011).
    • (2011) Am. J. Physiol. Endocrinol. Metab , vol.300 , pp. 145-154
    • Dasu, M.R.1    Jialal, I.2
  • 42
    • 12144290761 scopus 로고    scopus 로고
    • Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo
    • Kim, H. J. et al. Differential effects of interleukin-6 and -10 on skeletal muscle and liver insulin action in vivo. Diabetes 53, 1060-1067 (2004).
    • (2004) Diabetes , vol.53 , pp. 1060-1067
    • Kim, H.J.1
  • 43
    • 0037012406 scopus 로고    scopus 로고
    • Postprandial endothelial activation in healthy subjects and in type 2 diabetic patients: Role of fat and carbohydrate meals
    • Nappo, F. et al. Postprandial endothelial activation in healthy subjects and in type 2 diabetic patients: role of fat and carbohydrate meals. J. Am. Coll. Cardiol. 39, 1145-1150 (2002).
    • (2002) J. Am. Coll. Cardiol , vol.39 , pp. 1145-1150
    • Nappo, F.1
  • 44
    • 33846821855 scopus 로고    scopus 로고
    • Postprandial variations of plasma inflammatory markers in abdominally obese men
    • Blackburn, P et al. Postprandial variations of plasma inflammatory markers in abdominally obese men. Obesity (Silver Spring) 14, 1747-1754 (2006).
    • (2006) Obesity (Silver Spring) , vol.14 , pp. 1747-1754
    • Blackburn, P.1
  • 45
    • 35948940807 scopus 로고    scopus 로고
    • Prolonged reactive oxygen species generation and nuclear factor-KB activation after a high-fat, high-carbohydrate meal in the obese
    • Patel, C. et al. Prolonged reactive oxygen species generation and nuclear factor-KB activation after a high-fat, high-carbohydrate meal in the obese. J. Clin. Endocrinol. Metab. 92, 4476-4479 (2007).
    • (2007) J. Clin. Endocrinol. Metab , vol.92 , pp. 4476-4479
    • Patel, C.1
  • 46
    • 33947388389 scopus 로고    scopus 로고
    • The metabolic syndrome sensitizes leukocytes for glucose-induced immune gene expression
    • Kempf, K. et al. The metabolic syndrome sensitizes leukocytes for glucose-induced immune gene expression. J. Mol. Med. 85, 389-396 (2007).
    • (2007) J. Mol. Med , vol.85 , pp. 389-396
    • Kempf, K.1
  • 47
    • 35648996899 scopus 로고    scopus 로고
    • Obese reproductive-age women exhibit a proatherogenic inflammatory response during hyperglycemia
    • Gonzalez, F., Rote, N. S., Minium, J., O’leary, V. B. and Kirwan, J. P Obese reproductive-age women exhibit a proatherogenic inflammatory response during hyperglycemia. Obesity (Silver Spring) 15, 2436-2444 (2007).
    • (2007) Obesity (Silver Spring) , vol.15 , pp. 2436-2444
    • Gonzalez, F.1    Rote, N.S.2    Minium, J.3    O’Leary, V.B.4    Kirwan, J.P.5
  • 48
    • 77950290067 scopus 로고    scopus 로고
    • Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression
    • Zacharioudaki, V. et al. Adiponectin promotes endotoxin tolerance in macrophages by inducing IRAK-M expression. J. Immunol. 182, 6444-6451 (2009).
    • (2009) J. Immunol , vol.182 , pp. 6444-6451
    • Zacharioudaki, V.1
  • 49
    • 77955494890 scopus 로고    scopus 로고
    • The obese healthy paradox: Is inflammation the answer
    • Barbarroja, N. et al. The obese healthy paradox: is inflammation the answer? Biochem. J. 430, 141-149 (2010).
    • (2010) Biochem. J , vol.430 , pp. 141-149
    • Barbarroja, N.1
  • 50
    • 70349769764 scopus 로고    scopus 로고
    • Reactive oxygen species production by mitochondria
    • Lambert, A. J. and Brand, M. D. Reactive oxygen species production by mitochondria. Methods Mol. Biol. 554, 165-181 (2009).
    • (2009) Methods Mol. Biol , vol.554 , pp. 165-181
    • Lambert, A.J.1    Brand, M.D.2
  • 51
    • 73449124480 scopus 로고    scopus 로고
    • Mitochondrial glutathione, a key survival antioxidant. Antioxid. Redox
    • Mari, M., Morales, A., Colell, A., Garcia-Ruiz, C. and Fernandez-Checa, J. C. Mitochondrial glutathione, a key survival antioxidant. Antioxid. Redox. Signal. 11, 2685-2700 (2009).
    • (2009) Signal , vol.11 , pp. 2685-2700
    • Mari, M.1    Morales, A.2    Colell, A.3    Garcia-Ruiz, C.4    Fernandez-Checa, J.C.5
  • 52
    • 53349101264 scopus 로고    scopus 로고
    • Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia
    • El Osta, A. et al. Transient high glucose causes persistent epigenetic changes and altered gene expression during subsequent normoglycemia. J. Exp. Med. 205, 2409-2417 (2008).
    • (2008) J. Exp. Med , vol.205 , pp. 2409-2417
    • El Osta, A.1
  • 53
    • 48749100078 scopus 로고    scopus 로고
    • Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells
    • Lambertucci, R. H. et al. Palmitate increases superoxide production through mitochondrial electron transport chain and NADPH oxidase activity in skeletal muscle cells. J. Cell Physiol. 216, 796-804 (2008).
    • (2008) J. Cell Physiol , vol.216 , pp. 796-804
    • Lambertucci, R.H.1
  • 54
    • 34547119919 scopus 로고    scopus 로고
    • High glucose induces IL-1p expression in human monocytes: Mechanistic insights
    • Dasu, M. R., Devaraj, S. and Jialal, I. High glucose induces IL-1p expression in human monocytes: mechanistic insights. Am. J. Physiol. Endocrinol. Metab. 293, 337-346 (2007).
    • (2007) Am. J. Physiol. Endocrinol. Metab , vol.293 , pp. 337-346
    • Dasu, M.R.1    Devaraj, S.2    Jialal, I.3
  • 55
    • 0042266366 scopus 로고    scopus 로고
    • Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity
    • Short, K. R. et al. Impact of aerobic exercise training on age-related changes in insulin sensitivity and muscle oxidative capacity. Diabetes 52, 1888-1896 (2003).
    • (2003) Diabetes , vol.52 , pp. 1888-1896
    • Short, K.R.1
  • 56
    • 66649109663 scopus 로고    scopus 로고
    • Antioxidants prevent health- promoting effects of physical exercise in humans
    • Ristow, M. et al. Antioxidants prevent health- promoting effects of physical exercise in humans. Proc. Natl Acad. Sci. USA 106, 8665-8670 (2009).
    • (2009) Proc. Natl Acad. Sci. USA , vol.106 , pp. 8665-8670
    • Ristow, M.1
  • 57
    • 38149131289 scopus 로고    scopus 로고
    • Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance
    • Gomez-Cabrera, M. C. et al. Oral administration of vitamin C decreases muscle mitochondrial biogenesis and hampers training-induced adaptations in endurance performance. Am. J. Clin. Nutr. 87, 142-149 (2008).
    • (2008) Am. J. Clin. Nutr , vol.87 , pp. 142-149
    • Gomez-Cabrera, M.C.1
  • 58
    • 79955423639 scopus 로고    scopus 로고
    • Antioxidant supplementation reduces skeletal muscle mitochondrial biogenesis. Med. Sci
    • Strobel, N. A. et al. Antioxidant supplementation reduces skeletal muscle mitochondrial biogenesis. Med. Sci. Sports Exerc. 43, 1017-1024 (2011).
    • (2011) Sports Exerc , vol.43 , pp. 1017-1024
    • Strobel, N.A.1
  • 59
    • 78650913154 scopus 로고    scopus 로고
    • Impaired redox signaling and antioxidant gene expression in endothelial cells in diabetes: A role for mitochondria and the nuclear factor-E2-related factor 2-Kelch-like ECH-associated protein 1 defense pathway. Antioxid. Redox
    • Cheng, X., Siow, R. C. and Mann, G. E. Impaired redox signaling and antioxidant gene expression in endothelial cells in diabetes: a role for mitochondria and the nuclear factor-E2-related factor 2-Kelch-like ECH-associated protein 1 defense pathway. Antioxid. Redox. Signal. 14, 469-487 (2011).
    • (2011) Signal , vol.14 , pp. 469-487
    • Cheng, X.1    Siow, R.C.2    Mann, G.E.3
  • 60
    • 79953810587 scopus 로고    scopus 로고
    • Oltipraz upregulates the nuclear factor (Erythroid-derived 2)-like 2 (NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high-fat diet in C57BL/6J mice
    • Yu, Z. et al. Oltipraz upregulates the nuclear factor (erythroid-derived 2)-like 2 (NRF2) antioxidant system and prevents insulin resistance and obesity induced by a high-fat diet in C57BL/6J mice. Diabetologia 54, 922-934 (2011).
    • (2011) Diabetologia , vol.54 , pp. 922-934
    • Yu, Z.1
  • 61
    • 48449094498 scopus 로고    scopus 로고
    • AMPK and PPARS agonists are exercise mimetics
    • Narkar, V. A. et al. AMPK and PPARS agonists are exercise mimetics. Cell 134, 405-415 (2008).
    • (2008) Cell , vol.134 , pp. 405-415
    • Narkar, V.A.1
  • 62
    • 77952548782 scopus 로고    scopus 로고
    • How increased oxidative stress promotes longevity and metabolic health: The concept of mitochondrial hormesis (mitohormesis). Exp
    • Ristow, M. and Zarse, K. How increased oxidative stress promotes longevity and metabolic health: the concept of mitochondrial hormesis (mitohormesis). Exp. Gerontol. 45, 410-418 (2010).
    • (2010) Gerontol , vol.45 , pp. 410-418
    • Ristow, M.1    Zarse, K.2
  • 63
    • 62749130586 scopus 로고    scopus 로고
    • Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet
    • Gupte, A. A., Bomhoff, G. L., Swerdlow, R. H. and Geiger, P. C. Heat treatment improves glucose tolerance and prevents skeletal muscle insulin resistance in rats fed a high-fat diet. Diabetes 58, 567-578 (2009).
    • (2009) Diabetes , vol.58 , pp. 567-578
    • Gupte, A.A.1    Bomhoff, G.L.2    Swerdlow, R.H.3    Geiger, P.C.4
  • 64
    • 77249122068 scopus 로고    scopus 로고
    • Mild thermotolerance induced at 40 degrees C increases antioxidants and protects HeLa cells against mitochondrial apoptosis induced by hydrogen peroxide
    • Pallepati, P. and Averill-Bates, D. Mild thermotolerance induced at 40 degrees C increases antioxidants and protects HeLa cells against mitochondrial apoptosis induced by hydrogen peroxide: Role of p53. Arch. Biochem. Biophys. 495, 97-111 (2010).
    • (2010) Role of P53. Arch. Biochem. Biophys. , vol.495 , pp. 97-111
    • Pallepati, P.1    Averill-Bates, D.2
  • 65
    • 34748850786 scopus 로고    scopus 로고
    • Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell
    • Schulz, T. J. et al. Glucose restriction extends Caenorhabditis elegans life span by inducing mitochondrial respiration and increasing oxidative stress. Cell. Metab. 6, 280-293 (2007).
    • (2007) Metab , vol.6 , pp. 280-293
    • Schulz, T.J.1
  • 66
    • 78650177082 scopus 로고    scopus 로고
    • Inhibition of respiration extends C. Elegans life span via reactive oxygen species that increase HIF-1 activity
    • Lee, S. J., Hwang, A. B. and Kenyon, C. Inhibition of respiration extends C. elegans life span via reactive oxygen species that increase HIF-1 activity. Curr. Biol. 20, 2131-2136 (2010).
    • (2010) Curr. Biol , vol.20 , pp. 2131-2136
    • Lee, S.J.1    Hwang, A.B.2    Kenyon, C.3
  • 67
    • 70350365865 scopus 로고    scopus 로고
    • C. Elegans as model for the study of high glucose-mediated life span reduction
    • Schlotterer, A. et al. C. elegans as model for the study of high glucose-mediated life span reduction. Diabetes 58, 2450-2456 (2009).
    • (2009) Diabetes , vol.58 , pp. 2450-2456
    • Schlotterer, A.1
  • 68
    • 0036788293 scopus 로고    scopus 로고
    • Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes
    • Kelley, D. E., He, J., Menshikova, E. V. and Ritov, V. B. Dysfunction of mitochondria in human skeletal muscle in type 2 diabetes. Diabetes 51, 2944-2950 (2002).
    • (2002) Diabetes , vol.51 , pp. 2944-2950
    • Kelley, D.E.1    He, J.2    Menshikova, E.V.3    Ritov, V.B.4
  • 69
    • 1642377274 scopus 로고    scopus 로고
    • Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes
    • Petersen, K. F., Dufour, S., Befroy, D., Garcia, R. and Shulman, G. I. Impaired mitochondrial activity in the insulin-resistant offspring of patients with type 2 diabetes. N. Engl. J. Med. 350, 664-671 (2004).
    • (2004) N. Engl. J. Med , vol.350 , pp. 664-671
    • Petersen, K.F.1    Dufour, S.2    Befroy, D.3    Garcia, R.4    Shulman, G.I.5
  • 70
    • 33847611885 scopus 로고    scopus 로고
    • Patients with type 2 diabetes have normal mitochondrial function in skeletal muscle
    • Boushel, R. et al. Patients with type 2 diabetes have normal mitochondrial function in skeletal muscle. Diabetologia 50, 790-796 (2007).
    • (2007) Diabetologia , vol.50 , pp. 790-796
    • Boushel, R.1
  • 71
    • 0942301241 scopus 로고    scopus 로고
    • Disassociation of muscle triglyceride content and insulin sensitivity after exercise training in patients with type 2 diabetes
    • Bruce, C. R., Kriketos, A. D., Cooney, G. J. and Hawley, J. A. Disassociation of muscle triglyceride content and insulin sensitivity after exercise training in patients with type 2 diabetes. Diabetologia 47, 23-30 (2004).
    • (2004) Diabetologia , vol.47 , pp. 23-30
    • Bruce, C.R.1    Kriketos, A.D.2    Cooney, G.J.3    Hawley, J.A.4
  • 72
    • 20444466581 scopus 로고    scopus 로고
    • Contrasting clinical and cardiovascular risk status between early and later onset type 2 diabetes
    • Hatunic, M., Burns, N., Finucane, F., Mannion, C. and Nolan, J. J. Contrasting clinical and cardiovascular risk status between early and later onset type 2 diabetes. Diab. Vasc. Dis. Res. 2, 73-75 (2005).
    • (2005) Diab. Vasc. Dis. Res , vol.2 , pp. 73-75
    • Hatunic, M.1    Burns, N.2    Finucane, F.3    Mannion, C.4    Nolan, J.J.5
  • 73
    • 41449091754 scopus 로고    scopus 로고
    • Early-onset type 2 diabetes mellitus: An increasing phenomenon of elevated cardiovascular risk. Expert
    • Song, S. H. and Hardisty, C. A. Early-onset type 2 diabetes mellitus: an increasing phenomenon of elevated cardiovascular risk. Expert Rev. Cardiovasc. Ther. 6, 315-322 (2008).
    • (2008) Rev. Cardiovasc. Ther , vol.6 , pp. 315-322
    • Song, S.H.1    Hardisty, C.A.2
  • 74
    • 77649244994 scopus 로고    scopus 로고
    • Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1a/mitofusin-2 regulatory pathway in response to physical activity
    • Hernandez-Alvarez, M. I. et al. Subjects with early-onset type 2 diabetes show defective activation of the skeletal muscle PGC-1a/mitofusin-2 regulatory pathway in response to physical activity. Diabetes Care 33, 645-651 (2010).
    • (2010) Diabetes Care , vol.33 , pp. 645-651
    • Hernandez-Alvarez, M.I.1
  • 75
    • 34249945638 scopus 로고    scopus 로고
    • Early-onset type 2 diabetes in obese white subjects is characterised by a marked defect in p cell insulin secretion, severe insulin resistance and a lack of response to aerobic exercise training
    • Burns, N. et al. Early-onset type 2 diabetes in obese white subjects is characterised by a marked defect in p cell insulin secretion, severe insulin resistance and a lack of response to aerobic exercise training. Diabetologia 50, 1500-1508 (2007).
    • (2007) Diabetologia , vol.50 , pp. 1500-1508
    • Burns, N.1
  • 76
    • 60749137649 scopus 로고    scopus 로고
    • Extremely short duration high intensity interval training substantially improves insulin action in young healthy males. BMC Endocr
    • Babraj, J. A. et al. Extremely short duration high intensity interval training substantially improves insulin action in young healthy males. BMC Endocr. Disord. 9, 3 (2009).
    • (2009) Disord , vol.9 , pp. 3
    • Babraj, J.A.1
  • 77
    • 72449181721 scopus 로고    scopus 로고
    • Improved insulin sensitivity after exercise: Focus on insulin signaling
    • Frosig, C. and Richter, E. A. Improved insulin sensitivity after exercise: focus on insulin signaling. Obesity (Silver Spring) 17 (Suppl. 3), 15-20 (2009).
    • (2009) Obesity (Silver Spring) , vol.17 , pp. 15-20
    • Frosig, C.1    Richter, E.A.2
  • 78
    • 79955972054 scopus 로고    scopus 로고
    • The effect of rowing on endothelial function and insulin action in healthy controls and in patients with type 2 diabetes
    • Olsen, D. B., Scheede-Bergdahl, C., Reving, D., Boushel, R. and Dela, F. The effect of rowing on endothelial function and insulin action in healthy controls and in patients with type 2 diabetes. Scand. J. Med. Sci. Sports 21, 420-430 (2011).
    • (2011) Scand. J. Med. Sci. Sports , vol.21 , pp. 420-430
    • Olsen, D.B.1    Scheede-Bergdahl, C.2    Reving, D.3    Boushel, R.4    Dela, F.5
  • 79
    • 77950349827 scopus 로고    scopus 로고
    • Restoration of muscle mitochondrial function and metabolic flexibility in type 2 diabetes by exercise training is paralleled by increased myocellular fat storage and improved insulin sensitivity
    • Meex, R. C. et al. Restoration of muscle mitochondrial function and metabolic flexibility in type 2 diabetes by exercise training is paralleled by increased myocellular fat storage and improved insulin sensitivity. Diabetes 59, 572-579 (2010).
    • (2010) Diabetes , vol.59 , pp. 572-579
    • Meex, R.C.1
  • 80
    • 77955508579 scopus 로고    scopus 로고
    • Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals
    • Phielix, E., Meex, R., Moonen-Kornips, E., Hesselink, M. K. and Schrauwen, P. Exercise training increases mitochondrial content and ex vivo mitochondrial function similarly in patients with type 2 diabetes and in control individuals. Diabetologia 53, 1714-1721 (2010).
    • (2010) Diabetologia , vol.53 , pp. 1714-1721
    • Phielix, E.1    Meex, R.2    Moonen-Kornips, E.3    Hesselink, M.K.4    Schrauwen, P.5
  • 81
    • 77956013253 scopus 로고    scopus 로고
    • Minireview: Inflammation and obesity pathogenesis: The hypothalamus heats up
    • Thaler, J. P and Schwartz, M. W. Minireview: inflammation and obesity pathogenesis: the hypothalamus heats up. Endocrinology 151, 4109-4115 (2010).
    • (2010) Endocrinology , vol.151 , pp. 4109-4115
    • Thaler, J.P.1    Schwartz, M.W.2
  • 82
    • 77956772446 scopus 로고    scopus 로고
    • Sensing the fuels: Glucose and lipid signaling in the CNS controlling energy homeostasis
    • Jordan, S. D., Konner, A. C. and Bruning, J. C. Sensing the fuels: glucose and lipid signaling in the CNS controlling energy homeostasis. Cell. Mol. Life Sci. 67, 3255-3273 (2010).
    • (2010) Cell. Mol. Life Sci , vol.67 , pp. 3255-3273
    • Jordan, S.D.1    Konner, A.C.2    Bruning, J.C.3
  • 83
    • 33745828301 scopus 로고    scopus 로고
    • Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells
    • Wei, Y, Wang, D., Topczewski, F. and Pagliassotti, M. J. Saturated fatty acids induce endoplasmic reticulum stress and apoptosis independently of ceramide in liver cells. Am. J. Physiol. Endocrinol. Metab. 291, 275-281 (2006).
    • (2006) Am. J. Physiol. Endocrinol. Metab , vol.291 , pp. 275-281
    • Wei, Y.1    Wang, D.2    Topczewski, F.3    Pagliassotti, M.J.4
  • 84
    • 39149104320 scopus 로고    scopus 로고
    • The role for endoplasmic reticulum stress in diabetes mellitus. Endocr
    • Eizirik, D. L., Cardozo, A. K. and Cnop, M. The role for endoplasmic reticulum stress in diabetes mellitus. Endocr. Rev. 29, 42-61 (2008).
    • (2008) Rev , vol.29 , pp. 42-61
    • Eizirik, D.L.1    Cardozo, A.K.2    Cnop, M.3
  • 85
    • 77950343252 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress and the inflammatory basis of metabolic disease
    • Hotamisligil, G. S. Endoplasmic reticulum stress and the inflammatory basis of metabolic disease. Cell 140, 900-917 (2010).
    • (2010) Cell , vol.140 , pp. 900-917
    • Hotamisligil, G.S.1
  • 86
    • 34250899722 scopus 로고    scopus 로고
    • Signal integration in the endoplasmic reticulum unfolded protein response
    • Ron, D. and Walter, P Signal integration in the endoplasmic reticulum unfolded protein response. Nat. Rev. Mol. Cell Biol. 8, 519-529 (2007).
    • (2007) Nat. Rev. Mol. Cell Biol , vol.8 , pp. 519-529
    • Ron, D.1    Walter, P.2
  • 87
    • 33748069813 scopus 로고    scopus 로고
    • Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes
    • Ozcan, U. et al. Chemical chaperones reduce ER stress and restore glucose homeostasis in a mouse model of type 2 diabetes. Science 313, 1137-1140 (2006).
    • (2006) Science , vol.313 , pp. 1137-1140
    • Ozcan, U.1
  • 88
    • 78650826465 scopus 로고    scopus 로고
    • Endoplasmic reticulum chaperon tauroursodeoxycholic acid alleviates obesity- induced myocardial contractile dysfunction
    • Ceylan-Isik, A. F., Sreejayan, N. and Ren, J. Endoplasmic reticulum chaperon tauroursodeoxycholic acid alleviates obesity- induced myocardial contractile dysfunction. J. Mol. Cell Cardiol. 50, 107-116 (2011).
    • (2011) J. Mol. Cell Cardiol , vol.50 , pp. 107-116
    • Ceylan-Isik, A.F.1    Sreejayan, N.2    Ren, J.3
  • 89
    • 77955411159 scopus 로고    scopus 로고
    • Tauroursodeoxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women
    • Kars, M. et al. Tauroursodeoxycholic acid may improve liver and muscle but not adipose tissue insulin sensitivity in obese men and women. Diabetes 59, 1899-1905 (2010).
    • (2010) Diabetes , vol.59 , pp. 1899-1905
    • Kars, M.1
  • 90
    • 79953001199 scopus 로고    scopus 로고
    • Preconditioning with endoplasmic reticulum stress mitigates retinal endothelial inflammation via activation of X-box binding protein 1
    • Li, J., Wang, J. J. and Zhang, S. X. Preconditioning with endoplasmic reticulum stress mitigates retinal endothelial inflammation via activation of X-box binding protein 1. J. Biol. Chem. 286, 4912-4921 (2011).
    • (2011) J. Biol. Chem , vol.286 , pp. 4912-4921
    • Li, J.1    Wang, J.J.2    Zhang, S.X.3
  • 91
    • 69849104186 scopus 로고    scopus 로고
    • A subcytotoxic dose of subtilase cytotoxin prevents lipopolysaccharide- induced inflammatory responses, depending on its capacity to induce the unfolded protein response
    • Harama, D. et al. A subcytotoxic dose of subtilase cytotoxin prevents lipopolysaccharide- induced inflammatory responses, depending on its capacity to induce the unfolded protein response. J. Immunol. 183, 1368-1374 (2009).
    • (2009) J. Immunol , vol.183 , pp. 1368-1374
    • Harama, D.1
  • 92
    • 5644231992 scopus 로고    scopus 로고
    • Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes
    • Ozcan, U. et al. Endoplasmic reticulum stress links obesity, insulin action, and type 2 diabetes. Science 306, 457-61 (2004).
    • (2004) Science , vol.306 , pp. 457-461
    • Ozcan, U.1
  • 93
    • 19944430402 scopus 로고    scopus 로고
    • Involvement of endoplasmic reticulum stress in insulin resistance and diabetes
    • Nakatani, Y et al. Involvement of endoplasmic reticulum stress in insulin resistance and diabetes. J. Biol. Chem. 280, 847-851 (2005).
    • (2005) J. Biol. Chem , vol.280 , pp. 847-851
    • Nakatani, Y.1
  • 94
    • 66449137379 scopus 로고    scopus 로고
    • GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice
    • Kammoun, H. L. et al. GRP78 expression inhibits insulin and ER stress-induced SREBP-1c activation and reduces hepatic steatosis in mice. J. Clin. Invest. 119, 1201-1215 (2009).
    • (2009) J. Clin. Invest , vol.119 , pp. 1201-1215
    • Kammoun, H.L.1
  • 95
    • 77449096697 scopus 로고    scopus 로고
    • Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance
    • Ye, R. et al. Grp78 heterozygosity promotes adaptive unfolded protein response and attenuates diet-induced obesity and insulin resistance. Diabetes 59, 6-16 (2010).
    • (2010) Diabetes , vol.59 , pp. 6-16
    • Ye, R.1
  • 96
    • 79952122987 scopus 로고    scopus 로고
    • Deletion of Nck1 attenuates hepatic ER stress signaling, improves glucose tolerance and insulin signaling in liver of obese mice
    • Latreille, M., Laberge, M. K., Bourret, G., Yamani, L. and Larose, L. Deletion of Nck1 attenuates hepatic ER stress signaling, improves glucose tolerance and insulin signaling in liver of obese mice. Am. J. Physiol. Endocrinol. Metab. 300, E423-E434 (2011).
    • (2011) Am. J. Physiol. Endocrinol. Metab , vol.300 , pp. E423-E434
    • Latreille, M.1    Laberge, M.K.2    Bourret, G.3    Yamani, L.4    Larose, L.5
  • 97
    • 79551510124 scopus 로고    scopus 로고
    • The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1a/ATF6a complex. Cell
    • Wu, J. et al. The unfolded protein response mediates adaptation to exercise in skeletal muscle through a PGC-1a/ATF6a complex. Cell. Metab. 13, 160-169 (2011).
    • (2011) Metab , vol.13 , pp. 160-169
    • Wu, J.1
  • 98
    • 77952552782 scopus 로고    scopus 로고
    • Stress and hormetic regulation of the aging process. Ageing Res
    • Salminen, A. and Kaarniranta, K. ER stress and hormetic regulation of the aging process. Ageing Res. Rev. 9, 211-217 (2010).
    • (2010) Rev , vol.9 , pp. 211-217
    • Salminen, A.1    Kaarniranta, K.2
  • 99
    • 34547638958 scopus 로고    scopus 로고
    • High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated (3-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes
    • Huang, C. J. et al. High expression rates of human islet amyloid polypeptide induce endoplasmic reticulum stress mediated 3-cell apoptosis, a characteristic of humans with type 2 but not type 1 diabetes. Diabetes 56, 2016-2027 (2007).
    • (2007) Diabetes , vol.56 , pp. 2016-2027
    • Huang, C.J.1
  • 100
    • 64649101777 scopus 로고    scopus 로고
    • Successful versus failed adaptation to high-fat diet-induced insulin resistance the role of IAPP-induced 3-cell endoplasmic reticulum stress
    • Matveyenko, A. V., Gurlo, T., Daval, M., Butler, A. E. and Butler, P. C. Successful versus failed adaptation to high-fat diet-induced insulin resistance: the role of IAPP-induced 3-cell endoplasmic reticulum stress. Diabetes 58, 906-916 (2009).
    • (2009) Diabetes , vol.58 , pp. 906-916
    • Matveyenko, A.V.1    Gurlo, T.2    Daval, M.3    Butler, A.E.4    Butler, P.C.5
  • 101
    • 0009760791 scopus 로고    scopus 로고
    • Heat shock protein hsp70 overexpression confers resistance against nitric oxide
    • Bellmann, K., Jaattela, M., Wissing, D., Burkart, V. and Kolb, H. Heat shock protein hsp70 overexpression confers resistance against nitric oxide. FEBS Lett. 391, 185-188 (1996).
    • (1996) FEBS Lett , vol.391 , pp. 185-188
    • Bellmann, K.1    Jaattela, M.2    Wissing, D.3    Burkart, V.4    Kolb, H.5
  • 102
    • 0030980991 scopus 로고    scopus 로고
    • Low stress response enhances vulnerability of islet cells in diabetes-prone BB rats
    • Bellmann, K., Hui, L., Radons, J., Burkart, V. and Kolb, H. Low stress response enhances vulnerability of islet cells in diabetes-prone BB rats. Diabetes 46, 232-236 (1997).
    • (1997) Diabetes , vol.46 , pp. 232-236
    • Bellmann, K.1    Hui, L.2    Radons, J.3    Burkart, V.4    Kolb, H.5
  • 103
    • 0026052415 scopus 로고
    • Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 13-induced impaired 3-cell function
    • Margulis, B. A., Sandler, S., Eizirik, D. L., Welsh, N. and Welsh, M. Liposomal delivery of purified heat shock protein hsp70 into rat pancreatic islets as protection against interleukin 13-induced impaired 3-cell function. Diabetes 40, 1418-1422 (1991).
    • (1991) Diabetes , vol.40 , pp. 1418-1422
    • Margulis, B.A.1    Sandler, S.2    Eizirik, D.L.3    Welsh, N.4    Welsh, M.5
  • 104
    • 33646533330 scopus 로고    scopus 로고
    • Interferon-y potentiates endoplasmic reticulum stress- induced death by reducing pancreatic 3 cell defence mechanisms
    • Pirot, P, Eizirik, D. L. and Cardozo, A. K. Interferon-y potentiates endoplasmic reticulum stress- induced death by reducing pancreatic 3 cell defence mechanisms. Diabetologia 49, 1229-1236 (2006).
    • (2006) Diabetologia , vol.49 , pp. 1229-1236
    • Pirot, P.1    Eizirik, D.L.2    Cardozo, A.K.3
  • 105
    • 49649084031 scopus 로고    scopus 로고
    • Initiation and execution of lipotoxic ER stress in pancreatic 3-cells
    • Cunha, D. A. et al. Initiation and execution of lipotoxic ER stress in pancreatic 3-cells. J. Cell Sci. 121, 2308-2318 (2008).
    • (2008) J. Cell Sci , vol.121 , pp. 2308-2318
    • Cunha, D.A.1
  • 106
    • 34147106529 scopus 로고    scopus 로고
    • Global profiling of genes modified by endoplasmic reticulum stress in pancreatic 3 cells reveals the early degradation of insulin mRNAs
    • Pirot, P. et al. Global profiling of genes modified by endoplasmic reticulum stress in pancreatic 3 cells reveals the early degradation of insulin mRNAs. Diabetologia 50, 1006-1014 (2007).
    • (2007) Diabetologia , vol.50 , pp. 1006-1014
    • Pirot, P.1
  • 107
    • 33751069967 scopus 로고    scopus 로고
    • Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins
    • Rutkowski, D. T. et al. Adaptation to ER stress is mediated by differential stabilities of pro-survival and pro-apoptotic mRNAs and proteins. PLoS Biol. 4, e374 (2006).
    • (2006) Plos Biol , vol.374 , pp. 4
    • Rutkowski, D.T.1
  • 108
    • 77952574173 scopus 로고    scopus 로고
    • ER stress in pancreatic 3 cells: The thin red line between adaptation and failure
    • Eizirik, D. L. and Cnop, M. ER stress in pancreatic 3 cells: the thin red line between adaptation and failure. Sci.Signal. 3, pe7 (2010).
    • (2010) Sci.Signal
    • Eizirik, D.L.1    Cnop, M.2
  • 109
    • 0041853778 scopus 로고    scopus 로고
    • Protection of renal epithelial cells against oxidative injury by endoplasmic reticulum stress preconditioning is mediated by ERK1/2 activation
    • Hung, C. C., Ichimura, T., Stevens, J. L. and Bonventre, J. V. Protection of renal epithelial cells against oxidative injury by endoplasmic reticulum stress preconditioning is mediated by ERK1/2 activation. J. Biol. Chem. 278, 29317-29326 (2003).
    • (2003) J. Biol. Chem , vol.278 , pp. 29317-29326
    • Hung, C.C.1    Ichimura, T.2    Stevens, J.L.3    Bonventre, J.V.4
  • 110
    • 73249116246 scopus 로고    scopus 로고
    • Glucagon-like peptide-1 agonists protect pancreatic (3-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB
    • Cunha, D. A. et al. Glucagon-like peptide-1 agonists protect pancreatic 3-cells from lipotoxic endoplasmic reticulum stress through upregulation of BiP and JunB. Diabetes 58, 2851-2862 (2009).
    • (2009) Diabetes , vol.58 , pp. 2851-2862
    • Cunha, D.A.1
  • 111
    • 33750448469 scopus 로고    scopus 로고
    • GLP-1 receptor activation improves 3 cell function and survival following induction of endoplasmic reticulum stress
    • Yusta, B. et al. GLP-1 receptor activation improves 3 cell function and survival following induction of endoplasmic reticulum stress. Cell. Metab. 4, 391-06 (2006).
    • (2006) Cell. Metab , vol.4 , pp. 391-406
    • Yusta, B.1
  • 112
    • 72049110972 scopus 로고    scopus 로고
    • Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets
    • Johnson, J. D. et al. Different effects of FK506, rapamycin, and mycophenolate mofetil on glucose-stimulated insulin release and apoptosis in human islets. Cell Transplant. 18, 833-845 (2009).
    • (2009) Cell Transplant , vol.18 , pp. 833-845
    • Johnson, J.D.1
  • 113
    • 73349106529 scopus 로고    scopus 로고
    • The effects of glucagon-like peptide-1 on the 3 cell. Diab. Obes
    • Vilsboll, T. The effects of glucagon-like peptide-1 on the 3 cell. Diab. Obes. Metab. 11 (Suppl. 3), 11-18 (2009).
    • (2009) Metab , vol.11 , pp. 11-18
    • Vilsboll, T.1
  • 114
    • 77949817711 scopus 로고    scopus 로고
    • AMPK and SIRT1: A long¬standing partnership
    • Ruderman, N. B. et al. AMPK and SIRT1: a long¬standing partnership? Am. J. Physiol. Endocrinol. Metab. 298, 751-760 (2010).
    • (2010) Am. J. Physiol. Endocrinol. Metab , vol.298 , pp. 751-760
    • Ruderman, N.B.1
  • 115
    • 78650987216 scopus 로고    scopus 로고
    • Sirtuin-1 regulation of mammalian metabolism. Trends Mol
    • Gillum, M. P., Erion, D. M. and Shulman, G. I. Sirtuin-1 regulation of mammalian metabolism. Trends Mol. Med. 17, 8-13 (2010).
    • (2010) Med , vol.17 , pp. 8-13
    • Gillum, M.P.1    Erion, D.M.2    Shulman, G.I.3
  • 116
    • 79953206276 scopus 로고    scopus 로고
    • Resveratrol potentiates glucose- stimulated insulin secretion in INS-1E 3-cells and human islets through a SIRT1-dependent mechanism
    • Vetterli, L., Brun, T., Giovannoni, L., Bosco, D. and Maechler, P. Resveratrol potentiates glucose- stimulated insulin secretion in INS-1E 3-cells and human islets through a SIRT1-dependent mechanism. J. Biol. Chem. 286, 6049-6060 (2011).
    • (2011) J. Biol. Chem , vol.286 , pp. 6049-6060
    • Vetterli, L.1    Brun, T.2    Giovannoni, L.3    Bosco, D.4    Maechler, P.5
  • 117
    • 0033625664 scopus 로고    scopus 로고
    • Interleukin-13-induced alteration in a 3-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis
    • Ling, Z., Van de Casteele, M., Eizirik, D. L. and Pipeleers, D. G. Interleukin-13-induced alteration in a 3-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine-induced apoptosis. Diabetes 49, 340-345 (2000).
    • (2000) Diabetes , vol.49 , pp. 340-345
    • Ling, Z.1    Van De Casteele, M.2    Eizirik, D.L.3    Pipeleers, D.G.4
  • 118
    • 77749234186 scopus 로고    scopus 로고
    • Current status of islet cell replacement and regeneration therapy
    • Halban, P. A., German, M. S., Kahn, S. E. and Weir, G. C. Current status of islet cell replacement and regeneration therapy. J. Clin. Endocrinol. Metab. 95, 1034-1043 (2010).
    • (2010) J. Clin. Endocrinol. Metab , vol.95 , pp. 1034-1043
    • Halban, P.A.1    German, M.S.2    Kahn, S.E.3    Weir, G.C.4
  • 119
    • 79251634527 scopus 로고    scopus 로고
    • 3 cell regeneration in human pancreas. Semin
    • Gianani, R. 3 cell regeneration in human pancreas. Semin. Immunopathol. 33, 23-27 (2011).
    • (2011) Immunopathol , vol.33 , pp. 23-27
    • Gianani, R.1
  • 120
    • 77955272726 scopus 로고    scopus 로고
    • Giving and taking: Endothelial and 3-cells in the islets of Langerhans
    • Eberhard, D., Kragl, M. and Lammert, E. ‘Giving and taking’: endothelial and 3-cells in the islets of Langerhans. Trends Endocrinol. Metab. 21, 457-63 (2010).
    • (2010) Trends Endocrinol. Metab. , vol.21 , pp. 457-463
    • Eberhard, D.1    Kragl, M.2    Lammert, E.3
  • 121
    • 77649103802 scopus 로고    scopus 로고
    • Novel biological insights emerging from genetic studies of type 2 diabetes and related metabolic traits
    • De Silva, N. M. and Frayling, T. M. Novel biological insights emerging from genetic studies of type 2 diabetes and related metabolic traits. Curr. Opin. Lipidol. 21, 44-50 (2010).
    • (2010) Curr. Opin. Lipidol , vol.21 , pp. 44-50
    • De Silva, N.M.1    Frayling, T.M.2
  • 123
    • 0025600472 scopus 로고
    • Hyperglycemia-induced 3 cell toxicity. The fate of pancreatic islets transplanted into diabetic mice is dependent on their genetic background
    • Korsgren, O., Jansson, L., Sandler, S., and Andersson, A. Hyperglycemia-induced 3 cell toxicity. The fate of pancreatic islets transplanted into diabetic mice is dependent on their genetic background. J. Clin. Invest. 86, 2161-2168 (1990).
    • (1990) J. Clin. Invest , vol.86 , pp. 2161-2168
    • Korsgren, O.1    Jansson, L.2    Sandler, S.3    Andersson, A.4
  • 124
    • 55749086379 scopus 로고    scopus 로고
    • Association of SIRT1 gene variation with visceral obesity. Hum
    • Peeters, A. V. et al. Association of SIRT1 gene variation with visceral obesity. Hum. Genet. 124, 431-36 (2008).
    • (2008) Genet , vol.124 , pp. 431-436
    • Peeters, A.V.1
  • 125
    • 70349974821 scopus 로고    scopus 로고
    • Genetic variations in regulatory pathways of fatty acid and glucose metabolism are associated with obesity phenotypes: A population-based cohort study
    • van den Berg, S. W. et al. Genetic variations in regulatory pathways of fatty acid and glucose metabolism are associated with obesity phenotypes: a population-based cohort study. Int. J. Obes. (Lond.) 33, 1143-1152 (2009).
    • (2009) Int. J. Obes. (Lond.) , vol.33 , pp. 1143-1152
    • Van Den Berg, S.W.1
  • 126
    • 73249152036 scopus 로고    scopus 로고
    • SIRT1 genetic variation is related to BMI and risk of obesity
    • Zillikens, M. C. et al. SIRT1 genetic variation is related to BMI and risk of obesity. Diabetes 58, 2828-2834 (2009).
    • (2009) Diabetes , vol.58 , pp. 2828-2834
    • Zillikens, M.C.1
  • 127
    • 58749099124 scopus 로고    scopus 로고
    • SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention—the TULIP Study. BMC Med
    • Weyrich, P. et al. SIRT1 genetic variants associate with the metabolic response of Caucasians to a controlled lifestyle intervention—the TULIP Study. BMC Med. Genet. 9, 100 (2008).
    • (2008) Genet , vol.9 , pp. 100
    • Weyrich, P.1
  • 128
    • 77949397703 scopus 로고    scopus 로고
    • The association between the peroxisome proliferator-activated receptor- gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: A HuGE review and meta-analysis
    • Gouda, H. N. et al. The association between the peroxisome proliferator-activated receptor- gamma2 (PPARG2) Pro12Ala gene variant and type 2 diabetes mellitus: a HuGE review and meta-analysis. Am. J. Epidemiol. 171, 645-655 (2010).
    • (2010) Am. J. Epidemiol , vol.171 , pp. 645-655
    • Gouda, H.N.1
  • 129
    • 77956922366 scopus 로고    scopus 로고
    • Association between heme oxygenase-1 gene promoter polymorphisms and type 2 diabetes mellitus: A HuGE review and meta-analysis
    • Bao, W. et al. Association between heme oxygenase-1 gene promoter polymorphisms and type 2 diabetes mellitus: a HuGE review and meta-analysis. Am. J. Epidemiol. 172, 631-636 (2010).
    • (2010) Am. J. Epidemiol , vol.172 , pp. 631-636
    • Bao, W.1
  • 130
    • 48349144852 scopus 로고    scopus 로고
    • Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell
    • Pearson, K. J. et al. Resveratrol delays age-related deterioration and mimics transcriptional aspects of dietary restriction without extending life span. Cell. Metab. 8, 157-168 (2008).
    • (2008) Metab , vol.8 , pp. 157-168
    • Pearson, K.J.1
  • 131
    • 79953193036 scopus 로고    scopus 로고
    • Sensing of energy and nutrients by AMP-activated protein kinase
    • Hardie, D. G. Sensing of energy and nutrients by AMP-activated protein kinase. Am. J. Clin. Nutr. 93, 891-896 (2011).
    • (2011) Am. J. Clin. Nutr , vol.93 , pp. 891-896
    • Hardie, D.G.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.