-
1
-
-
35549006000
-
Blood-brain barrier and energy balance
-
10.1038/oby.2006.315 1:CAS:528:DC%2BD28XhtV2qu7jN
-
WA Banks 2006 Blood-brain barrier and energy balance Obesity (Silver Spring) 14 Suppl 5 234S 237S 10.1038/oby.2006.315 1:CAS:528:DC%2BD28XhtV2qu7jN
-
(2006)
Obesity (Silver Spring)
, vol.14
, Issue.SUPPL 5
-
-
Banks, W.A.1
-
2
-
-
72449184473
-
Integrative neurobiology of energy homeostasis-neurocircuits, signals and mediators
-
19729032 10.1016/j.yfrne.2009.08.002 1:CAS:528:DC%2BD1MXhs1WgsbvP
-
C Sanchez-Lasheras A Christine Konner JC Bruning 2009 Integrative neurobiology of energy homeostasis-neurocircuits, signals and mediators Front Neuroendocrinol 31 4 15 19729032 10.1016/j.yfrne.2009.08.002 1:CAS:528:DC%2BD1MXhs1WgsbvP
-
(2009)
Front Neuroendocrinol
, vol.31
, pp. 4-15
-
-
Sanchez-Lasheras, C.1
Christine Konner, A.2
Bruning, J.C.3
-
3
-
-
0003659796
-
Leçons de physiologie experimentale appliquée à la medecine
-
C Bernard 1855 Leçons de physiologie experimentale appliquée à la medecine Baillère et Fils Paris 2 296 313
-
(1855)
Baillère et Fils Paris
, vol.2
, pp. 296-313
-
-
Bernard, C.1
-
4
-
-
0002712310
-
Glucostatic mechanism of regulation of food intake
-
13063674 10.1056/NEJM195307022490104 1:STN:280:DyaG3s%2FovVKmuw%3D%3D
-
J Mayer 1953 Glucostatic mechanism of regulation of food intake N Engl J Med 249 13 16 13063674 10.1056/NEJM195307022490104 1:STN:280: DyaG3s%2FovVKmuw%3D%3D
-
(1953)
N Engl J Med
, vol.249
, pp. 13-16
-
-
Mayer, J.1
-
5
-
-
0014683812
-
Glucose and osmosensitive neurones of the rat hypothalamus
-
5778398 10.1038/222282a0 1:STN:280:DyaF1M7lvVGrtg%3D%3D
-
Y Oomura T Ono H Ooyama MJ Wayner 1969 Glucose and osmosensitive neurones of the rat hypothalamus Nature 222 282 284 5778398 10.1038/222282a0 1:STN:280:DyaF1M7lvVGrtg%3D%3D
-
(1969)
Nature
, vol.222
, pp. 282-284
-
-
Oomura, Y.1
Ono, T.2
Ooyama, H.3
Wayner, M.J.4
-
6
-
-
0001643038
-
Activity of single neurons in the hypothalamic feeding centers: Effect of glucose
-
14237464 1:STN:280:DyaF2M%2FktFyrsQ%3D%3D
-
BK Anand GS Chhina KN Sharma S Dua B Singh 1964 Activity of single neurons in the hypothalamic feeding centers: effect of glucose Am J Physiol 207 1146 1154 14237464 1:STN:280:DyaF2M%2FktFyrsQ%3D%3D
-
(1964)
Am J Physiol
, vol.207
, pp. 1146-1154
-
-
Anand, B.K.1
Chhina, G.S.2
Sharma, K.N.3
Dua, S.4
Singh, B.5
-
7
-
-
0021249617
-
Neural network of glucose monitoring system
-
6090526 10.1016/0165-1838(84)90033-X 1:STN:280:DyaL2M%2Fgsl2qtA%3D%3D
-
Y Oomura H Yoshimatsu 1984 Neural network of glucose monitoring system J Auton Nerv Syst 10 359 372 6090526 10.1016/0165-1838(84)90033-X 1:STN:280:DyaL2M%2Fgsl2qtA%3D%3D
-
(1984)
J Auton Nerv Syst
, vol.10
, pp. 359-372
-
-
Oomura, Y.1
Yoshimatsu, H.2
-
8
-
-
2642641299
-
Glucose-induced intracellular ion changes in sugar-sensitive hypothalamic neurons
-
9535943 1:CAS:528:DyaK1cXjtVCmsrs%3D
-
IA Silver M Erecinska 1998 Glucose-induced intracellular ion changes in sugar-sensitive hypothalamic neurons J Neurophysiol 79 1733 1745 9535943 1:CAS:528:DyaK1cXjtVCmsrs%3D
-
(1998)
J Neurophysiol
, vol.79
, pp. 1733-1745
-
-
Silver, I.A.1
Erecinska, M.2
-
9
-
-
7044253373
-
+ channel-independent mechanism is involved in glucose-excited neurons of mouse arcuate nucleus
-
DOI 10.2337/diabetes.53.11.2767
-
X Fioramonti A Lorsignol A Taupignon L Penicaud 2004 A new ATP-sensitive K+ channel-independent mechanism is involved in glucose-excited neurons of mouse arcuate nucleus Diabetes 53 2767 2775 15504956 10.2337/diabetes.53.11.2767 1:CAS:528:DC%2BD2cXpvV2it74%3D (Pubitemid 39425901)
-
(2004)
Diabetes
, vol.53
, Issue.11
, pp. 2767-2775
-
-
Fioramonti, X.1
Lorsignol, A.2
Taupignon, A.3
Penicaud, L.4
-
11
-
-
34548207654
-
Brain glucose sensing, counterregulation, and energy homeostasis
-
1:CAS:528:DC%2BD2sXhtVentrbO
-
N Marty M Dallaporta B Thorens 2007 Brain glucose sensing, counterregulation, and energy homeostasis Physiology (Bethesda) 22 241 251 1:CAS:528:DC%2BD2sXhtVentrbO
-
(2007)
Physiology (Bethesda)
, vol.22
, pp. 241-251
-
-
Marty, N.1
Dallaporta, M.2
Thorens, B.3
-
12
-
-
0017887676
-
Projections from the nucleus of the solitary tract in the rat
-
DOI 10.1016/0306-4522(78)90102-1
-
R Norgren 1978 Projections from the nucleus of the solitary tract in the rat Neuroscience 3 207 218 733004 10.1016/0306-4522(78)90102-1 1:STN:280:DyaE1M%2FpsVanug%3D%3D (Pubitemid 8319765)
-
(1978)
Neuroscience
, vol.3
, Issue.2
, pp. 207-218
-
-
Norgren, R.1
-
13
-
-
27344433932
-
Agouti-related peptide-expressing neurons are mandatory for feeding
-
DOI 10.1038/nn1548, PII N1548
-
E Gropp M Shanabrough E Borok AW Xu R Janoschek T Buch L Plum N Balthasar B Hampel A Waisman GS Barsh TL Horvath JC Bruning 2005 Agouti-related peptide-expressing neurons are mandatory for feeding Nat Neurosci 8 1289 1291 16158063 10.1038/nn1548 1:CAS:528:DC%2BD2MXhtVeqs7zI (Pubitemid 41630413)
-
(2005)
Nature Neuroscience
, vol.8
, Issue.10
, pp. 1289-1291
-
-
Gropp, E.1
Shanabrough, M.2
Borok, E.3
Xu, A.W.4
Janoschek, R.5
Buch, T.6
Plum, L.7
Balthasar, N.8
Hampel, B.9
Waisman, A.10
Barsh, G.S.11
Horvath, T.L.12
Bruning, J.C.13
-
14
-
-
68949120737
-
Control of energy homeostasis by insulin and leptin: Targeting the arcuate nucleus and beyond
-
19351541 10.1016/j.physbeh.2009.03.027 1:CAS:528:DC%2BD1MXmvF2itLY%3D
-
AC Konner T Klockener JC Bruning 2009 Control of energy homeostasis by insulin and leptin: targeting the arcuate nucleus and beyond Physiol Behav 97 632 638 19351541 10.1016/j.physbeh.2009.03.027 1:CAS:528:DC%2BD1MXmvF2itLY%3D
-
(2009)
Physiol Behav
, vol.97
, pp. 632-638
-
-
Konner, A.C.1
Klockener, T.2
Bruning, J.C.3
-
15
-
-
0027488373
-
The prohormone convertases PC1 and PC2 mediate distinct endoproteolytic cleavages in a strict temporal order during proopiomelanocortin biosynthetic processing
-
8380577 1:CAS:528:DyaK3sXhs1Wnsr8%3D
-
A Zhou BT Bloomquist RE Mains 1993 The prohormone convertases PC1 and PC2 mediate distinct endoproteolytic cleavages in a strict temporal order during proopiomelanocortin biosynthetic processing J Biol Chem 268 1763 1769 8380577 1:CAS:528:DyaK3sXhs1Wnsr8%3D
-
(1993)
J Biol Chem
, vol.268
, pp. 1763-1769
-
-
Zhou, A.1
Bloomquist, B.T.2
Mains, R.E.3
-
16
-
-
0030614331
-
Role of melanocortlnergic neurons in feeding and the agouti obesity syndrome
-
DOI 10.1038/385165a0
-
W Fan BA Boston RA Kesterson VJ Hruby RD Cone 1997 Role of melanocortinergic neurons in feeding and the agouti obesity syndrome Nature 385 165 168 8990120 10.1038/385165a0 1:CAS:528:DyaK2sXks1Witw%3D%3D (Pubitemid 27034218)
-
(1997)
Nature
, vol.385
, Issue.6612
, pp. 165-168
-
-
Fan, W.1
Boston, B.A.2
Kesterson, R.A.3
Hruby, V.J.4
Cone, R.D.5
-
17
-
-
33645089926
-
A role for beta-melanocyte-stimulating hormone in human body-weight regulation
-
16459315 10.1016/j.cmet.2006.01.007 1:CAS:528:DC%2BD28XhvFyjtLo%3D
-
H Biebermann TR Castaneda F van Landeghem A von Deimling F Escher G Brabant J Hebebrand A Hinney MH Tschop A Gruters H Krude 2006 A role for beta-melanocyte-stimulating hormone in human body-weight regulation Cell Metab 3 141 146 16459315 10.1016/j.cmet.2006.01.007 1:CAS:528:DC%2BD28XhvFyjtLo%3D
-
(2006)
Cell Metab
, vol.3
, pp. 141-146
-
-
Biebermann, H.1
Castaneda, T.R.2
Van Landeghem, F.3
Von Deimling, A.4
Escher, F.5
Brabant, G.6
Hebebrand, J.7
Hinney, A.8
Tschop, M.H.9
Gruters, A.10
Krude, H.11
-
18
-
-
33645048441
-
A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance
-
16459314 10.1016/j.cmet.2006.01.006 1:CAS:528:DC%2BD28XhvFyjtL0%3D
-
YS Lee BG Challis DA Thompson GS Yeo JM Keogh ME Madonna V Wraight M Sims V Vatin D Meyre J Shield C Burren Z Ibrahim T Cheetham P Swift A Blackwood CC Hung NJ Wareham P Froguel GL Millhauser S O'Rahilly IS Farooqi 2006 A POMC variant implicates beta-melanocyte-stimulating hormone in the control of human energy balance Cell Metab 3 135 140 16459314 10.1016/j.cmet.2006.01.006 1:CAS:528:DC%2BD28XhvFyjtL0%3D
-
(2006)
Cell Metab
, vol.3
, pp. 135-140
-
-
Lee, Y.S.1
Challis, B.G.2
Thompson, D.A.3
Yeo, G.S.4
Keogh, J.M.5
Madonna, M.E.6
Wraight, V.7
Sims, M.8
Vatin, V.9
Meyre, D.10
Shield, J.11
Burren, C.12
Ibrahim, Z.13
Cheetham, T.14
Swift, P.15
Blackwood, A.16
Hung, C.C.17
Wareham, N.J.18
Froguel, P.19
Millhauser, G.L.20
O'Rahilly, S.21
Farooqi, I.S.22
more..
-
19
-
-
0028606308
-
Differential effects of melanocortin peptides on neural melanocortin receptors
-
7808440 1:CAS:528:DyaK2MXivFKqt7k%3D
-
RA Adan RD Cone JP Burbach WH Gispen 1994 Differential effects of melanocortin peptides on neural melanocortin receptors Mol Pharmacol 46 1182 1190 7808440 1:CAS:528:DyaK2MXivFKqt7k%3D
-
(1994)
Mol Pharmacol
, vol.46
, pp. 1182-1190
-
-
Adan, R.A.1
Cone, R.D.2
Burbach, J.P.3
Gispen, W.H.4
-
20
-
-
0028237203
-
The human melanocyte stimulating hormone receptor has evolved to become "super-sensitive" to melanocortin peptides
-
7926261 10.1016/0303-7207(94)90113-9 1:STN:280:DyaK2M%2FhtFShsQ%3D%3D
-
KG Mountjoy 1994 The human melanocyte stimulating hormone receptor has evolved to become "super-sensitive" to melanocortin peptides Mol Cell Endocrinol 102 R7 R11 7926261 10.1016/0303-7207(94)90113-9 1:STN:280: DyaK2M%2FhtFShsQ%3D%3D
-
(1994)
Mol Cell Endocrinol
, vol.102
-
-
Mountjoy, K.G.1
-
21
-
-
0021713735
-
Neuropeptide Y: Stimulation of feeding and drinking by injection into the paraventricular nucleus
-
DOI 10.1016/0024-3205(84)90032-8
-
BG Stanley SF Leibowitz 1984 Neuropeptide Y: stimulation of feeding and drinking by injection into the paraventricular nucleus Life Sci 35 2635 2642 6549039 10.1016/0024-3205(84)90032-8 1:CAS:528:DyaL2MXhvVaqug%3D%3D (Pubitemid 15221101)
-
(1984)
Life Sciences
, vol.35
, Issue.26
, pp. 2635-2642
-
-
Stanley, B.G.1
Leibowitz, S.F.2
-
22
-
-
0021248888
-
Neuropeptide y and human pancreatic polypeptide stimulate feeding behavior in rats
-
6547387 10.1210/endo-115-1-427 1:CAS:528:DyaL2cXks1Knurc%3D
-
JT Clark PS Kalra WR Crowley SP Kalra 1984 Neuropeptide Y and human pancreatic polypeptide stimulate feeding behavior in rats Endocrinology 115 427 429 6547387 10.1210/endo-115-1-427 1:CAS:528:DyaL2cXks1Knurc%3D
-
(1984)
Endocrinology
, vol.115
, pp. 427-429
-
-
Clark, J.T.1
Kalra, P.S.2
Crowley, W.R.3
Kalra, S.P.4
-
23
-
-
0030764741
-
Antagonism of Central Melanocortin receptors in vitro and in vivo by agouti-related protein
-
DOI 10.1126/science.278.5335.135
-
MM Ollmann BD Wilson YK Yang JA Kerns Y Chen I Gantz GS Barsh 1997 Antagonism of central melanocortin receptors in vitro and in vivo by agouti-related protein Science 278 135 138 9311920 10.1126/science.278.5335.135 1:CAS:528:DyaK2sXmsV2ltrw%3D (Pubitemid 27446294)
-
(1997)
Science
, vol.278
, Issue.5335
, pp. 135-138
-
-
Ollmann, M.M.1
Wilson, B.D.2
Yang, Y.-K.3
Kerns, J.A.4
Chen, Y.5
Gantz, I.6
Barsh, G.S.7
-
24
-
-
0037387207
-
ATP channels
-
DOI 10.1210/en.2002-221033
-
N Ibrahim MA Bosch JL Smart J Qiu M Rubinstein OK Ronnekleiv MJ Low MJ Kelly 2003 Hypothalamic proopiomelanocortin neurons are glucose responsive and express K(ATP) channels Endocrinology 144 1331 1340 12639916 10.1210/en.2002-221033 1:CAS:528:DC%2BD3sXisVegsLs%3D (Pubitemid 36428475)
-
(2003)
Endocrinology
, vol.144
, Issue.4
, pp. 1331-1340
-
-
Ibrahim, N.1
Bosch, M.A.2
Smart, J.L.3
Qiu, J.4
Rubinstein, M.5
Ronnekleiv, O.K.6
Low, M.J.7
Kelly, M.J.8
-
25
-
-
0033515710
-
Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y
-
DOI 10.1016/S0304-3940(99)00185-8, PII S0304394099001858
-
S Muroya T Yada S Shioda M Takigawa 1999 Glucose-sensitive neurons in the rat arcuate nucleus contain neuropeptide Y Neurosci Lett 264 113 116 10320027 10.1016/S0304-3940(99)00185-8 1:CAS:528:DyaK1MXisFCrtbg%3D (Pubitemid 29195962)
-
(1999)
Neuroscience Letters
, vol.264
, Issue.1-3
, pp. 113-116
-
-
Muroya, S.1
Yada, T.2
Shioda, S.3
Takigawa, M.4
-
26
-
-
33845945261
-
Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity
-
DOI 10.1007/s00125-006-0473-3
-
PD Mountjoy SJ Bailey GA Rutter 2007 Inhibition by glucose or leptin of hypothalamic neurons expressing neuropeptide Y requires changes in AMP-activated protein kinase activity Diabetologia 50 168 177 17093945 10.1007/s00125-006- 0473-3 1:CAS:528:DC%2BD2sXot1Wg (Pubitemid 46035865)
-
(2007)
Diabetologia
, vol.50
, Issue.1
, pp. 168-177
-
-
Mountjoy, P.D.1
Bailey, S.J.2
Rutter, G.A.3
-
27
-
-
34248204584
-
Characterization of glucosensing neuron subpopulations in the arcuate nucleus: Integration in neuropeptide y and pro-opio melanocortin networks?
-
DOI 10.2337/db06-0567
-
X Fioramonti S Contie Z Song VH Routh A Lorsignol L Penicaud 2007 Characterization of glucosensing neuron subpopulations in the arcuate nucleus: integration in neuropeptide Y and pro-opio melanocortin networks? Diabetes 56 1219 1227 17261674 10.2337/db06-0567 1:CAS:528:DC%2BD2sXltlantb8%3D (Pubitemid 46715601)
-
(2007)
Diabetes
, vol.56
, Issue.5
, pp. 1219-1227
-
-
Fioramonti, X.1
Contie, S.2
Song, Z.3
Routh, V.H.4
Lorsignol, A.5
Penicaud, L.6
-
29
-
-
0032576592
-
Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area
-
DOI 10.1002/(SICI)1096-9861(19981228)402:4<442::AID-CNE2>3.0.CO;2-R
-
CF Elias CB Saper E Maratos-Flier NA Tritos C Lee J Kelly JB Tatro GE Hoffman MM Ollmann GS Barsh T Sakurai M Yanagisawa JK Elmquist 1998 Chemically defined projections linking the mediobasal hypothalamus and the lateral hypothalamic area J Comp Neurol 402 442 459 9862320 10.1002/(SICI)1096- 9861(19981228)402:4<442::AID-CNE2>3.0.CO;2-R 1:STN:280: DyaK1M%2FnslWgtA%3D%3D (Pubitemid 29001074)
-
(1998)
Journal of Comparative Neurology
, vol.402
, Issue.4
, pp. 442-459
-
-
Elias, C.F.1
Saper, C.B.2
Maratos-Flier, E.3
Tritos, N.A.4
Lee, C.5
Kelly, J.6
Tatro, J.B.7
Huffman, G.E.8
Ollmann, M.M.9
Barsh, G.S.10
Sakurai, T.11
Yanagisawa, M.12
Elmquist, J.K.13
-
30
-
-
0032576536
-
Hypocretin/orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: Relationship to the neuropeptide Y and agouti gene-related protein systems
-
DOI 10.1002/(SICI)1096-9861(19981228)402:4<460::AID-CNE3>3.0.CO;2-S
-
C Broberger L De Lecea JG Sutcliffe T Hokfelt 1998 Hypocretin/orexin- and melanin-concentrating hormone-expressing cells form distinct populations in the rodent lateral hypothalamus: relationship to the neuropeptide Y and agouti gene-related protein systems J Comp Neurol 402 460 474 9862321 10.1002/(SICI)1096-9861(19981228)402:4<460::AID-CNE3>3.0.CO;2-S 1:CAS:528:DyaK1MXmslE%3D (Pubitemid 29001075)
-
(1998)
Journal of Comparative Neurology
, vol.402
, Issue.4
, pp. 460-474
-
-
Broberger, C.1
De Lecea, L.2
Sutcliffe, J.G.3
Hokfelt, T.4
-
31
-
-
0035157768
-
Glucose sensing in pancreatic beta-cells: A model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus
-
11147773 10.2337/diabetes.50.1.1 1:CAS:528:DC%2BD3MXis1Ogtg%3D%3D
-
FC Schuit P Huypens H Heimberg DG Pipeleers 2001 Glucose sensing in pancreatic beta-cells: a model for the study of other glucose-regulated cells in gut, pancreas, and hypothalamus Diabetes 50 1 11 11147773 10.2337/diabetes.50. 1.1 1:CAS:528:DC%2BD3MXis1Ogtg%3D%3D
-
(2001)
Diabetes
, vol.50
, pp. 1-11
-
-
Schuit, F.C.1
Huypens, P.2
Heimberg, H.3
Pipeleers, D.G.4
-
32
-
-
0032829063
-
Hypothalamic glucose sensor: Similarities to and differences from pancreatic β-cell mechanisms
-
DOI 10.2337/diabetes.48.9.1763
-
XJ Yang LM Kow T Funabashi CV Mobbs 1999 Hypothalamic glucose sensor: similarities to and differences from pancreatic beta-cell mechanisms Diabetes 48 1763 1772 10480606 10.2337/diabetes.48.9.1763 1:CAS:528:DyaK1MXmtVaitL0%3D (Pubitemid 29415195)
-
(1999)
Diabetes
, vol.48
, Issue.9
, pp. 1763-1772
-
-
Yang, X.-J.1
Kow, L.-M.2
Funabashi, T.3
Mobbs, C.V.4
-
33
-
-
33847746338
-
Glucose sensing by hypothalamic neurones and pancreatic islet cells: AMPle evidence for common mechanisms?
-
DOI 10.1113/expphysiol.2006.036004
-
PD Mountjoy GA Rutter 2007 Glucose sensing by hypothalamic neurones and pancreatic islet cells: AMPle evidence for common mechanisms? Exp Physiol 92 311 319 17158178 10.1113/expphysiol.2006.036004 1:CAS:528:DC%2BD2sXkvFegs7o%3D (Pubitemid 46376321)
-
(2007)
Experimental Physiology
, vol.92
, Issue.2
, pp. 311-319
-
-
Mountjoy, P.D.1
Rutter, G.A.2
-
34
-
-
0015722983
-
Effect of carbohydrates upon fluorescence of reduced pyridine nucleotides from perifused isolated pancreatic islets
-
4149332 10.1007/BF00461692 1:CAS:528:DyaE2cXotVOmsQ%3D%3D
-
U Panten J Christians E von Kriegstein W Poser A Hasselblatt 1973 Effect of carbohydrates upon fluorescence of reduced pyridine nucleotides from perifused isolated pancreatic islets Diabetologia 9 477 482 4149332 10.1007/BF00461692 1:CAS:528:DyaE2cXotVOmsQ%3D%3D
-
(1973)
Diabetologia
, vol.9
, pp. 477-482
-
-
Panten, U.1
Christians, J.2
Von Kriegstein, E.3
Poser, W.4
Hasselblatt, A.5
-
35
-
-
0021741559
-
Glucose induces closure of single potassium channels in isolated rat pancreatic β-cells
-
DOI 10.1038/312446a0
-
FM Ashcroft DE Harrison SJ Ashcroft 1984 Glucose induces closure of single potassium channels in isolated rat pancreatic beta-cells Nature 312 446 448 6095103 10.1038/312446a0 1:CAS:528:DyaL2MXit1Smtg%3D%3D (Pubitemid 15217837)
-
(1984)
Nature
, vol.312
, Issue.5993
, pp. 446-448
-
-
Ashcroft, F.M.1
Harrison, D.E.2
Ashcroft, S.J.H.3
-
36
-
-
5044231048
-
Distribution and anatomical localization of the glucose transporter 2 (GLUT2) in the adult rat brain - An immunohistochemical study
-
DOI 10.1016/j.jchemneu.2004.05.009, PII S0891061804000742
-
M Arluison M Quignon P Nguyen B Thorens C Leloup L Penicaud 2004 Distribution and anatomical localization of the glucose transporter 2 (GLUT2) in the adult rat brain-an immunohistochemical study J Chem Neuroanat 28 117 136 15482899 10.1016/j.jchemneu.2004.05.009 1:CAS:528:DC%2BD2cXos1ersbc%3D (Pubitemid 39336524)
-
(2004)
Journal of Chemical Neuroanatomy
, vol.28
, Issue.3
, pp. 117-136
-
-
Arluison, M.1
Quignon, M.2
Nguyen, P.3
Thorens, B.4
Leloup, C.5
Penicaud, L.6
-
37
-
-
1442276966
-
Physiological and Molecular Characteristics of Rat Hypothalamic Ventromedial Nucleus Glucosensing Neurons
-
DOI 10.2337/diabetes.53.3.549
-
L Kang VH Routh EV Kuzhikandathil LD Gaspers BE Levin 2004 Physiological and molecular characteristics of rat hypothalamic ventromedial nucleus glucosensing neurons Diabetes 53 549 559 14988237 10.2337/diabetes.53.3.549 1:CAS:528:DC%2BD2cXhvFelurw%3D (Pubitemid 38270622)
-
(2004)
Diabetes
, vol.53
, Issue.3
, pp. 549-559
-
-
Kang, L.1
Routh, V.H.2
Kuzhikandathil, E.V.3
Gaspers, L.D.4
Levin, B.E.5
-
38
-
-
0028157201
-
Glucose transporter 2 (GLUT 2): Expression in specific brain nuclei
-
8199863 10.1016/0006-8993(94)90653-X 1:CAS:528:DyaK2cXitFegsr8%3D
-
C Leloup M Arluison N Lepetit N Cartier P Marfaing-Jallat P Ferre L Penicaud 1994 Glucose transporter 2 (GLUT 2): expression in specific brain nuclei Brain Res 638 221 226 8199863 10.1016/0006-8993(94)90653-X 1:CAS:528:DyaK2cXitFegsr8%3D
-
(1994)
Brain Res
, vol.638
, pp. 221-226
-
-
Leloup, C.1
Arluison, M.2
Lepetit, N.3
Cartier, N.4
Marfaing-Jallat, P.5
Ferre, P.6
Penicaud, L.7
-
39
-
-
10244241840
-
Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: Evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake
-
8863504 10.1046/j.1471-4159.1996.67051982.x 1:CAS:528:DyaK28XmsV2qsbo%3D
-
M Navarro F Rodriquez de Fonseca E Alvarez JA Chowen JA Zueco R Gomez J Eng E Blazquez 1996 Colocalization of glucagon-like peptide-1 (GLP-1) receptors, glucose transporter GLUT-2, and glucokinase mRNAs in rat hypothalamic cells: evidence for a role of GLP-1 receptor agonists as an inhibitory signal for food and water intake J Neurochem 67 1982 1991 8863504 10.1046/j.1471-4159.1996. 67051982.x 1:CAS:528:DyaK28XmsV2qsbo%3D
-
(1996)
J Neurochem
, vol.67
, pp. 1982-1991
-
-
Navarro, M.1
Rodriquez De Fonseca, F.2
Alvarez, E.3
Chowen, J.A.4
Zueco, J.A.5
Gomez, R.6
Eng, J.7
Blazquez, E.8
-
40
-
-
31044444108
-
Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocytedependent glucose sensors
-
DOI 10.1172/JCI26309
-
N Marty M Dallaporta M Foretz M Emery D Tarussio I Bady C Binnert F Beermann B Thorens 2005 Regulation of glucagon secretion by glucose transporter type 2 (glut2) and astrocyte-dependent glucose sensors J Clin Invest 115 3545 3553 16322792 10.1172/JCI26309 1:CAS:528:DC%2BD2MXhtlSqtLvK (Pubitemid 43121842)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.12
, pp. 3545-3553
-
-
Marty, N.1
Dallaporta, M.2
Foretz, M.3
Emery, M.4
Tarussio, D.5
Bady, I.6
Binnert, C.7
Beermann, F.8
Thorens, B.9
-
41
-
-
0030067124
-
Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm
-
8549869 10.2337/diabetes.45.2.223 1:CAS:528:DyaK28XjslWnsr4%3D
-
FM Matschinsky 1996 Banting Lecture 1995. A lesson in metabolic regulation inspired by the glucokinase glucose sensor paradigm Diabetes 45 223 241 8549869 10.2337/diabetes.45.2.223 1:CAS:528:DyaK28XjslWnsr4%3D
-
(1996)
Diabetes
, vol.45
, pp. 223-241
-
-
Matschinsky, F.M.1
-
42
-
-
0036303140
-
Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons
-
12086933 10.2337/diabetes.51.7.2056 1:CAS:528:DC%2BD38Xlt1Wltr8%3D
-
AA Dunn-Meynell VH Routh L Kang L Gaspers BE Levin 2002 Glucokinase is the likely mediator of glucosensing in both glucose-excited and glucose-inhibited central neurons Diabetes 51 2056 2065 12086933 10.2337/diabetes.51.7.2056 1:CAS:528:DC%2BD38Xlt1Wltr8%3D
-
(2002)
Diabetes
, vol.51
, pp. 2056-2065
-
-
Dunn-Meynell, A.A.1
Routh, V.H.2
Kang, L.3
Gaspers, L.4
Levin, B.E.5
-
43
-
-
0028101926
-
Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut
-
8106409 1:CAS:528:DyaK2cXhvVCmtLY%3D
-
TL Jetton Y Liang CC Pettepher EC Zimmerman FG Cox K Horvath FM Matschinsky MA Magnuson 1994 Analysis of upstream glucokinase promoter activity in transgenic mice and identification of glucokinase in rare neuroendocrine cells in the brain and gut J Biol Chem 269 3641 3654 8106409 1:CAS:528:DyaK2cXhvVCmtLY%3D
-
(1994)
J Biol Chem
, vol.269
, pp. 3641-3654
-
-
Jetton, T.L.1
Liang, Y.2
Pettepher, C.C.3
Zimmerman, E.C.4
Cox, F.G.5
Horvath, K.6
Matschinsky, F.M.7
Magnuson, M.A.8
-
44
-
-
0034115117
-
Localization of glucokinase gene expression in the rat brain
-
10905475 10.2337/diabetes.49.5.693 1:CAS:528:DC%2BD3cXjsF2msrw%3D
-
RM Lynch LS Tompkins HL Brooks AA Dunn-Meynell BE Levin 2000 Localization of glucokinase gene expression in the rat brain Diabetes 49 693 700 10905475 10.2337/diabetes.49.5.693 1:CAS:528:DC%2BD3cXjsF2msrw%3D
-
(2000)
Diabetes
, vol.49
, pp. 693-700
-
-
Lynch, R.M.1
Tompkins, L.S.2
Brooks, H.L.3
Dunn-Meynell, A.A.4
Levin, B.E.5
-
45
-
-
3242765290
-
The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides
-
DOI 10.2337/diabetes.53.8.1959
-
R Wang X Liu ST Hentges AA Dunn-Meynell BE Levin W Wang VH Routh 2004 The regulation of glucose-excited neurons in the hypothalamic arcuate nucleus by glucose and feeding-relevant peptides Diabetes 53 1959 1965 15277373 10.2337/diabetes.53.8.1959 1:CAS:528:DC%2BD2cXmtFGqsb4%3D (Pubitemid 38970742)
-
(2004)
Diabetes
, vol.53
, Issue.8
, pp. 1959-1965
-
-
Wang, R.1
Liu, X.2
Hentges, S.T.3
Dunn-Meynell, A.A.4
Levin, B.E.5
Wang, W.6
Routh, V.H.7
-
46
-
-
33644773627
-
Glucokinase is a critical regulator of ventromedial hypothalamic neuronal glucosensing
-
DOI 10.2337/diabetes.55.02.06.db05-1229
-
L Kang AA Dunn-Meynell VH Routh LD Gaspers Y Nagata T Nishimura J Eiki BB Zhang BE Levin 2006 Glucokinase is a critical regulator of ventromedial hypothalamic neuronal glucosensing Diabetes 55 412 420 16443775 10.2337/diabetes.55.02.06.db05-1229 1:CAS:528:DC%2BD28XhsFajs7g%3D (Pubitemid 43343271)
-
(2006)
Diabetes
, vol.55
, Issue.2
, pp. 412-420
-
-
Kang, L.1
Dunn-Meynell, A.A.2
Routh, V.H.3
Gaspers, L.D.4
Nagata, Y.5
Nishimura, T.6
Eiki, J.7
Zhang, B.B.8
Levin, B.E.9
-
47
-
-
0032787462
-
+ channels and insulin secretion: Their role in health and disease
-
DOI 10.1007/s001250051247
-
FM Ashcroft FM Gribble 1999 ATP-sensitive K+ channels and insulin secretion: their role in health and disease Diabetologia 42 903 919 10491749 10.1007/s001250051247 1:CAS:528:DyaK1MXkvF2ksLg%3D (Pubitemid 29369597)
-
(1999)
Diabetologia
, vol.42
, Issue.8
, pp. 903-919
-
-
Ashcroft, F.M.1
Gribble, F.M.2
-
48
-
-
0025186956
-
Tolbutamide excites rat glucoreceptive ventromedial hypothalamic neurones by indirect inhibition of ATP-K+ channels
-
2127550 1:CAS:528:DyaK3cXmt1Cnsbw%3D
-
ML Ashford PR Boden JM Treherne 1990 Tolbutamide excites rat glucoreceptive ventromedial hypothalamic neurones by indirect inhibition of ATP-K+ channels Br J Pharmacol 101 531 540 2127550 1:CAS:528:DyaK3cXmt1Cnsbw%3D
-
(1990)
Br J Pharmacol
, vol.101
, pp. 531-540
-
-
Ashford, M.L.1
Boden, P.R.2
Treherne, J.M.3
-
50
-
-
0032517821
-
+ channel in rat brain
-
DOI 10.1016/S0006-8993(98)00956-1, PII S0006899398009561
-
AA Dunn-Meynell NE Rawson BE Levin 1998 Distribution and phenotype of neurons containing the ATP-sensitive K+ channel in rat brain Brain Res 814 41 54 9838037 10.1016/S0006-8993(98)00956-1 1:CAS:528:DyaK1cXnsFWltL0%3D (Pubitemid 29023410)
-
(1998)
Brain Research
, vol.814
, Issue.1-2
, pp. 41-54
-
-
Dunn-Meynell, A.A.1
Rawson, N.E.2
Levin, B.E.3
-
51
-
-
0030874406
-
Histological markers of neuronal, axonal and astrocytic changes after lateral rigid impact traumatic brain injury
-
DOI 10.1016/S0006-8993(97)00210-2, PII S0006899397002102
-
AA Dunn-Meynell BE Levin 1997 Histological markers of neuronal, axonal and astrocytic changes after lateral rigid impact traumatic brain injury Brain Res 761 25 41 9247063 10.1016/S0006-8993(97)00210-2 1:CAS:528:DyaK2sXjslKmt7o%3D (Pubitemid 27314730)
-
(1997)
Brain Research
, vol.761
, Issue.1
, pp. 25-41
-
-
Dunn-Meynell, A.A.1
Levin, B.E.2
-
52
-
-
0031440266
-
Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels
-
DOI 10.1038/37379
-
D Spanswick MA Smith VE Groppi SD Logan ML Ashford 1997 Leptin inhibits hypothalamic neurons by activation of ATP-sensitive potassium channels Nature 390 521 525 9394003 10.1038/37379 1:CAS:528:DyaK2sXnvF2ntbc%3D (Pubitemid 28013134)
-
(1997)
Nature
, vol.390
, Issue.6659
, pp. 521-525
-
-
Spanswick, D.1
Smith, M.A.2
Groppi, V.E.3
Logan, S.D.4
Ashford, M.L.J.5
-
53
-
-
0035042796
-
ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis
-
11319559 1:CAS:528:DC%2BD3MXjt1ersbc%3D
-
T Miki B Liss K Minami T Shiuchi A Saraya Y Kashima M Horiuchi F Ashcroft Y Minokoshi J Roeper S Seino 2001 ATP-sensitive K+ channels in the hypothalamus are essential for the maintenance of glucose homeostasis Nat Neurosci 4 507 512 11319559 1:CAS:528:DC%2BD3MXjt1ersbc%3D
-
(2001)
Nat Neurosci
, vol.4
, pp. 507-512
-
-
Miki, T.1
Liss, B.2
Minami, K.3
Shiuchi, T.4
Saraya, A.5
Kashima, Y.6
Horiuchi, M.7
Ashcroft, F.8
Minokoshi, Y.9
Roeper, J.10
Seino, S.11
-
54
-
-
0035650534
-
Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus
-
11723049 10.2337/diabetes.50.12.2673 1:CAS:528:DC%2BD3MXovVOiu70%3D
-
Z Song BE Levin JJ McArdle N Bakhos VH Routh 2001 Convergence of pre- and postsynaptic influences on glucosensing neurons in the ventromedial hypothalamic nucleus Diabetes 50 2673 2681 11723049 10.2337/diabetes.50.12.2673 1:CAS:528:DC%2BD3MXovVOiu70%3D
-
(2001)
Diabetes
, vol.50
, pp. 2673-2681
-
-
Song, Z.1
Levin, B.E.2
McArdle, J.J.3
Bakhos, N.4
Routh, V.H.5
-
55
-
-
4644298411
-
+ channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses
-
DOI 10.2337/diabetes.53.10.2542
-
ML Evans RJ McCrimmon DE Flanagan T Keshavarz X Fan EC McNay RJ Jacob RS Sherwin 2004 Hypothalamic ATP-sensitive K+ channels play a key role in sensing hypoglycemia and triggering counterregulatory epinephrine and glucagon responses Diabetes 53 2542 2551 15448082 10.2337/diabetes.53.10.2542 1:CAS:528: DC%2BD2cXotFymtr4%3D (Pubitemid 39299260)
-
(2004)
Diabetes
, vol.53
, Issue.10
, pp. 2542-2551
-
-
Evans, M.L.1
McCrimmon, R.J.2
Flanagan, D.E.3
Keshavarz, T.4
Fan, X.5
McNay, E.C.6
Jacob, R.J.7
Sherwin, R.S.8
-
56
-
-
33644696261
-
+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats
-
DOI 10.2337/diabetes.54.11.3169
-
RJ McCrimmon ML Evans X Fan EC McNay O Chan Y Ding W Zhu DX Gram RS Sherwin 2005 Activation of ATP-sensitive K+ channels in the ventromedial hypothalamus amplifies counterregulatory hormone responses to hypoglycemia in normal and recurrently hypoglycemic rats Diabetes 54 3169 3174 16249441 10.2337/diabetes.54.11.3169 1:CAS:528:DC%2BD2MXht1Siu7fI (Pubitemid 43334371)
-
(2005)
Diabetes
, vol.54
, Issue.11
, pp. 3169-3174
-
-
McCrimmon, R.J.1
Evans, M.L.2
Fan, X.3
McNay, E.C.4
Chan, O.5
Ding, Y.6
Zhu, W.7
Gram, D.X.8
Sherwin, R.S.9
-
57
-
-
0033988307
-
+ channels in glucose- sensing in the rat solitary tract nucleus
-
DOI 10.1016/S0304-3940(99)00898-8, PII S0304394099008988
-
M Dallaporta J Perrin JC Orsini 2000 Involvement of adenosine triphosphate-sensitive K+ channels in glucose-sensing in the rat solitary tract nucleus Neurosci Lett 278 77 80 10643805 10.1016/S0304-3940(99)00898-8 1:CAS:528:DC%2BD3cXotFCm (Pubitemid 30009901)
-
(2000)
Neuroscience Letters
, vol.278
, Issue.1-2
, pp. 77-80
-
-
Dallaporta, M.1
Perrin, J.2
Orsini, J.-C.3
-
58
-
-
34548604499
-
Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity
-
DOI 10.1038/nature06098, PII NATURE06098
-
LE Parton CP Ye R Coppari PJ Enriori B Choi CY Zhang C Xu CR Vianna N Balthasar CE Lee JK Elmquist MA Cowley BB Lowell 2007 Glucose sensing by POMC neurons regulates glucose homeostasis and is impaired in obesity Nature 449 228 232 17728716 10.1038/nature06098 1:CAS:528:DC%2BD2sXhtVagtb3L (Pubitemid 47402365)
-
(2007)
Nature
, vol.449
, Issue.7159
, pp. 228-232
-
-
Parton, L.E.1
Ye, C.P.2
Coppari, R.3
Enriori, P.J.4
Choi, B.5
Zhang, C.-Y.6
Xu, C.7
Vianna, C.R.8
Balthasar, N.9
Lee, C.E.10
Elmquist, J.K.11
Cowley, M.A.12
Lowell, B.B.13
-
59
-
-
33845897913
-
+ conductances in CART and NPY/AgRP expressing neurons of the hypothalamic arcuate nucleus
-
DOI 10.1016/j.neuroscience.2006.09.059, PII S0306452206013091
-
M van den Top DJ Lyons K Lee E Coderre LP Renaud D Spanswick 2007 Pharmacological and molecular characterization of ATP-sensitive K(+) conductances in CART and NPY/AgRP expressing neurons of the hypothalamic arcuate nucleus Neuroscience 144 815 824 17137725 10.1016/j.neuroscience.2006.09.059 1:CAS:528:DC%2BD2sXhsFKkuw%3D%3D (Pubitemid 46019837)
-
(2007)
Neuroscience
, vol.144
, Issue.3
, pp. 815-824
-
-
Van Den Top, M.1
Lyons, D.J.2
Lee, K.3
Coderre, E.4
Renaud, L.P.5
Spanswick, D.6
-
60
-
-
0033104765
-
Glucose-receptive neurones in the rat ventromedial hypothalamus express KATP channels composed of Kir6.1 and SUR1 subunits
-
10050011 10.1111/j.1469-7793.1999.439ac.x 1:CAS:528:DyaK1MXisF2jsr0%3D
-
K Lee AK Dixon PJ Richardson RD Pinnock 1999 Glucose-receptive neurones in the rat ventromedial hypothalamus express KATP channels composed of Kir6.1 and SUR1 subunits J Physiol 515 Pt 2 439 452 10050011 10.1111/j.1469-7793.1999. 439ac.x 1:CAS:528:DyaK1MXisF2jsr0%3D
-
(1999)
J Physiol
, vol.515
, Issue.PART 2
, pp. 439-452
-
-
Lee, K.1
Dixon, A.K.2
Richardson, P.J.3
Pinnock, R.D.4
-
61
-
-
0025164846
-
Glucose, sulfonylureas, and neurotransmitter release: Role of ATP-sensitive K+ channels
-
2305257 10.1126/science.2305257 1:CAS:528:DyaK3cXhslakurs%3D
-
S Amoroso H Schmid-Antomarchi M Fosset M Lazdunski 1990 Glucose, sulfonylureas, and neurotransmitter release: role of ATP-sensitive K+ channels Science 247 852 854 2305257 10.1126/science.2305257 1:CAS:528:DyaK3cXhslakurs%3D
-
(1990)
Science
, vol.247
, pp. 852-854
-
-
Amoroso, S.1
Schmid-Antomarchi, H.2
Fosset, M.3
Lazdunski, M.4
-
62
-
-
2042449726
-
In vitro increase in intracellular calcium concentrations induced by low or high extracellular glucose levels in ependymocytes and serotonergic neurons of the rat lower brainstem
-
DOI 10.1210/en.2003-1191
-
R Moriyama H Tsukamura M Kinoshita H Okazaki Y Kato K Maeda 2004 In vitro increase in intracellular calcium concentrations induced by low or high extracellular glucose levels in ependymocytes and serotonergic neurons of the rat lower brainstem Endocrinology 145 2507 2515 14962992 10.1210/en.2003-1191 1:CAS:528:DC%2BD2cXjsV2jsLc%3D (Pubitemid 38535078)
-
(2004)
Endocrinology
, vol.145
, Issue.5
, pp. 2507-2515
-
-
Moriyama, R.1
Tsukamura, H.2
Kinoshita, M.3
Okazaki, H.4
Kato, Y.5
Maeda, K.-I.6
-
63
-
-
12144275681
-
Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus
-
DOI 10.2337/diabetes.54.1.15
-
Z Song VH Routh 2005 Differential effects of glucose and lactate on glucosensing neurons in the ventromedial hypothalamic nucleus Diabetes 54 15 22 15616006 10.2337/diabetes.54.1.15 1:CAS:528:DC%2BD2MXhtVWjur8%3D (Pubitemid 40105090)
-
(2005)
Diabetes
, vol.54
, Issue.1
, pp. 15-22
-
-
Song, Z.1
Routh, V.U.2
-
64
-
-
72449180982
-
Sweet taste signaling functions as a hypothalamic glucose sensor
-
19587847 10.3389/neuro.07.012.2009 1:CAS:528:DC%2BD1MXhtVShtLrN
-
X Ren L Zhou R Terwilliger SS Newton IE de Araujo 2009 Sweet taste signaling functions as a hypothalamic glucose sensor Front Integr Neurosci 3 12 19587847 10.3389/neuro.07.012.2009 1:CAS:528:DC%2BD1MXhtVShtLrN
-
(2009)
Front Integr Neurosci
, vol.3
, pp. 12
-
-
Ren, X.1
Zhou, L.2
Terwilliger, R.3
Newton, S.S.4
De Araujo, I.E.5
-
65
-
-
0016191102
-
Glucose inhibition of the glucose-sensitive neurone in the rat lateral hypothalamus
-
4818362 10.1038/247284a0 1:CAS:528:DyaE2cXktVWktbY%3D
-
Y Oomura H Ooyama M Sugimori T Nakamura Y Yamada 1974 Glucose inhibition of the glucose-sensitive neurone in the rat lateral hypothalamus Nature 247 284 286 4818362 10.1038/247284a0 1:CAS:528:DyaE2cXktVWktbY%3D
-
(1974)
Nature
, vol.247
, pp. 284-286
-
-
Oomura, Y.1
Ooyama, H.2
Sugimori, M.3
Nakamura, T.4
Yamada, Y.5
-
66
-
-
33646914929
-
+ Channels Mediate Inhibition of Orexin Neurons by Glucose
-
DOI 10.1016/j.neuron.2006.04.032, PII S0896627306003692
-
D Burdakov LT Jensen H Alexopoulos RH Williams IM Fearon I O'Kelly O Gerasimenko L Fugger A Verkhratsky 2006 Tandem-pore K+ channels mediate inhibition of orexin neurons by glucose Neuron 50 711 722 16731510 10.1016/j.neuron.2006.04.032 1:CAS:528:DC%2BD28XlvVakur8%3D (Pubitemid 43792383)
-
(2006)
Neuron
, vol.50
, Issue.5
, pp. 711-722
-
-
Burdakov, D.1
Jensen, L.T.2
Alexopoulos, H.3
Williams, R.H.4
Fearon, I.M.5
O'Kelly, I.6
Gerasimenko, O.7
Fugger, L.8
Verkhratsky, A.9
-
67
-
-
61449104516
-
Glucose inhibition persists in hypothalamic neurons lacking tandem-pore K+ channels
-
19244527 10.1523/JNEUROSCI.5764-08.2009 1:CAS:528:DC%2BD1MXislWhurk%3D
-
A Guyon MP Tardy C Rovere JL Nahon J Barhanin F Lesage 2009 Glucose inhibition persists in hypothalamic neurons lacking tandem-pore K+ channels J Neurosci 29 2528 2533 19244527 10.1523/JNEUROSCI.5764-08.2009 1:CAS:528:DC%2BD1MXislWhurk%3D
-
(2009)
J Neurosci
, vol.29
, pp. 2528-2533
-
-
Guyon, A.1
Tardy, M.P.2
Rovere, C.3
Nahon, J.L.4
Barhanin, J.5
Lesage, F.6
-
68
-
-
58149317260
-
Metabolism-independent sugar sensing in central orexin neurons
-
18591392 10.2337/db08-0548 1:CAS:528:DC%2BD1MXhs1KnsLk%3D
-
JA Gonzalez LT Jensen L Fugger D Burdakov 2008 Metabolism-independent sugar sensing in central orexin neurons Diabetes 57 2569 2576 18591392 10.2337/db08-0548 1:CAS:528:DC%2BD1MXhs1KnsLk%3D
-
(2008)
Diabetes
, vol.57
, pp. 2569-2576
-
-
Gonzalez, J.A.1
Jensen, L.T.2
Fugger, L.3
Burdakov, D.4
-
69
-
-
53849145356
-
Hypothalamic orexins/hypocretins as regulators of breathing
-
18828950 10.1017/S1462399408000823
-
RH Williams D Burdakov 2008 Hypothalamic orexins/hypocretins as regulators of breathing Expert Rev Mol Med 10 e28 18828950 10.1017/ S1462399408000823
-
(2008)
Expert Rev Mol Med
, vol.10
, pp. 28
-
-
Williams, R.H.1
Burdakov, D.2
-
70
-
-
34547629761
-
Hyperglycemia impairs glucose and insulin regulation of nitric oxide production in glucose-inhibited neurons in the ventromedial hypothalamus
-
17537841 1:CAS:528:DC%2BD2sXptlyrtL4%3D
-
DD Canabal JG Potian RG Duran JJ McArdle VH Routh 2007 Hyperglycemia impairs glucose and insulin regulation of nitric oxide production in glucose-inhibited neurons in the ventromedial hypothalamus Am J Physiol Regul Integr Comp Physiol 293 R592 R600 17537841 1:CAS:528:DC%2BD2sXptlyrtL4%3D
-
(2007)
Am J Physiol Regul Integr Comp Physiol
, vol.293
-
-
Canabal, D.D.1
Potian, J.G.2
Duran, R.G.3
McArdle, J.J.4
Routh, V.H.5
-
71
-
-
33745225026
-
AMP-activated protein kinase - Development of the energy sensor concept
-
DOI 10.1113/jphysiol.2006.108944
-
DG Hardie SA Hawley JW Scott 2006 AMP-activated protein kinase-development of the energy sensor concept J Physiol 574 7 15 16644800 10.1113/jphysiol.2006.108944 1:CAS:528:DC%2BD28XnsVyjurc%3D (Pubitemid 43905792)
-
(2006)
Journal of Physiology
, vol.574
, Issue.1
, pp. 7-15
-
-
Hardie, D.G.1
Hawley, S.A.2
Scott, J.W.3
-
72
-
-
20844451123
-
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
-
DOI 10.1016/j.cmet.2004.12.003, PII S1550413104000099
-
BB Kahn T Alquier D Carling DG Hardie 2005 AMP-activated protein kinase: ancient energy gauge provides clues to modern understanding of metabolism Cell Metab 1 15 25 16054041 10.1016/j.cmet.2004.12.003 1:CAS:528:DC%2BD2MXhtlaqs74%3D (Pubitemid 43960587)
-
(2005)
Cell Metabolism
, vol.1
, Issue.1
, pp. 15-25
-
-
Kahn, B.B.1
Alquier, T.2
Carling, D.3
Hardie, D.G.4
-
73
-
-
0031007065
-
The AMP-activated protein kinase-fuel gauge of the mammalian cell?
-
9208914 10.1111/j.1432-1033.1997.00259.x 1:CAS:528:DyaK2sXjvVGrsbs%3D
-
DG Hardie D Carling 1997 The AMP-activated protein kinase-fuel gauge of the mammalian cell? Eur J Biochem 246 259 273 9208914 10.1111/j.1432-1033.1997. 00259.x 1:CAS:528:DyaK2sXjvVGrsbs%3D
-
(1997)
Eur J Biochem
, vol.246
, pp. 259-273
-
-
Hardie, D.G.1
Carling, D.2
-
74
-
-
33646590947
-
Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake
-
16604086 10.1038/nm1392 1:CAS:528:DC%2BD28Xkt1Kjurc%3D
-
T Kitamura Y Feng Y Ido Kitamura SC Chua AW Xu GS Barsh L Rossetti D Accili 2006 Forkhead protein FoxO1 mediates Agrp-dependent effects of leptin on food intake Nat Med 12 5 534 540 16604086 10.1038/nm1392 1:CAS:528: DC%2BD28Xkt1Kjurc%3D
-
(2006)
Nat Med
, vol.12
, Issue.5
, pp. 534-540
-
-
Kitamura, T.1
Feng, Y.2
Ido Kitamura, Y.3
Chua, S.C.4
Xu, A.W.5
Barsh, G.S.6
Rossetti, L.7
Accili, D.8
-
75
-
-
70449699694
-
A role for the CREB co-activator CRTC2 in the hypothalamic mechanisms linking glucose sensing with gene regulation
-
19713961 10.1038/embor.2009.177 1:CAS:528:DC%2BD1MXhtVKjsbbF
-
RG Lerner C Depatie GA Rutter RA Screaton N Balthasar 2009 A role for the CREB co-activator CRTC2 in the hypothalamic mechanisms linking glucose sensing with gene regulation EMBO Rep 10 1175 1181 19713961 10.1038/embor.2009.177 1:CAS:528:DC%2BD1MXhtVKjsbbF
-
(2009)
EMBO Rep
, vol.10
, pp. 1175-1181
-
-
Lerner, R.G.1
Depatie, C.2
Rutter, G.A.3
Screaton, R.A.4
Balthasar, N.5
-
76
-
-
70349244719
-
AMP-activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons
-
19570894 10.1152/ajpcell.00127.2009 1:CAS:528:DC%2BD1MXht1yktbfI
-
BA Murphy KA Fakira Z Song A Beuve VH Routh 2009 AMP-activated protein kinase and nitric oxide regulate the glucose sensitivity of ventromedial hypothalamic glucose-inhibited neurons Am J Physiol Cell Physiol 297 C750 C758 19570894 10.1152/ajpcell.00127.2009 1:CAS:528:DC%2BD1MXht1yktbfI
-
(2009)
Am J Physiol Cell Physiol
, vol.297
-
-
Murphy, B.A.1
Fakira, K.A.2
Song, Z.3
Beuve, A.4
Routh, V.H.5
-
77
-
-
0033593634
-
Energy on demand
-
DOI 10.1126/science.283.5401.496
-
PJ Magistretti L Pellerin DL Rothman RG Shulman 1999 Energy on demand Science 283 496 497 9988650 10.1126/science.283.5401.496 1:CAS:528: DyaK1MXoslagsw%3D%3D (Pubitemid 29061181)
-
(1999)
Science
, vol.283
, Issue.5401
, pp. 496-497
-
-
Magistretti, P.J.1
Pellerin, L.2
Rothman, D.L.3
Shulman, R.G.4
-
78
-
-
0034721575
-
Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy
-
11098125 10.1016/S0306-4522(00)00294-3 1:CAS:528:DC%2BD3cXmvFymur0%3D
-
K Pierre L Pellerin R Debernardi BM Riederer PJ Magistretti 2000 Cell-specific localization of monocarboxylate transporters, MCT1 and MCT2, in the adult mouse brain revealed by double immunohistochemical labeling and confocal microscopy Neuroscience 100 617 627 11098125 10.1016/S0306-4522(00) 00294-3 1:CAS:528:DC%2BD3cXmvFymur0%3D
-
(2000)
Neuroscience
, vol.100
, pp. 617-627
-
-
Pierre, K.1
Pellerin, L.2
Debernardi, R.3
Riederer, B.M.4
Magistretti, P.J.5
-
79
-
-
0037107408
-
+ channels
-
DOI 10.1113/jphysiol.2002.022434
-
EK Ainscow S Mirshamsi T Tang ML Ashford GA Rutter 2002 Dynamic imaging of free cytosolic ATP concentration during fuel sensing by rat hypothalamic neurones: evidence for ATP-independent control of ATP-sensitive K(+) channels J Physiol 544 429 445 12381816 10.1113/jphysiol.2002.022434 1:CAS:528: DC%2BD38Xos12qur0%3D (Pubitemid 35244260)
-
(2002)
Journal of Physiology
, vol.544
, Issue.2
, pp. 429-445
-
-
Ainscow, E.K.1
Mirshamsi, S.2
Tang, T.3
Ashford, M.L.J.4
Rutter, G.A.5
-
80
-
-
23244458439
-
Medicine: Regulation of blood glucose by hypothalamic pyruvate metabolism
-
DOI 10.1126/science.1112085
-
TK Lam R Gutierrez-Juarez A Pocai L Rossetti 2005 Regulation of blood glucose by hypothalamic pyruvate metabolism Science 309 943 947 16081739 10.1126/science.1112085 1:CAS:528:DC%2BD2MXmvFSksr4%3D (Pubitemid 41099933)
-
(2005)
Science
, vol.309
, Issue.5736
, pp. 943-947
-
-
Lam, T.K.T.1
Gutierrez-Juarez, R.2
Pocai, A.3
Rossetti, L.4
-
81
-
-
12044255619
-
Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing
-
8106462 1:CAS:528:DyaK2cXhvVyht7g%3D
-
N Sekine V Cirulli R Regazzi LJ Brown E Gine J Tamarit-Rodriguez M Girotti S Marie MJ MacDonald CB Wollheim 1994 Low lactate dehydrogenase and high mitochondrial glycerol phosphate dehydrogenase in pancreatic beta-cells. Potential role in nutrient sensing J Biol Chem 269 4895 4902 8106462 1:CAS:528:DyaK2cXhvVyht7g%3D
-
(1994)
J Biol Chem
, vol.269
, pp. 4895-4902
-
-
Sekine, N.1
Cirulli, V.2
Regazzi, R.3
Brown, L.J.4
Gine, E.5
Tamarit-Rodriguez, J.6
Girotti, M.7
Marie, S.8
MacDonald, M.J.9
Wollheim, C.B.10
-
82
-
-
0033431775
-
Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells
-
10587526 10.1172/JCI7515 1:CAS:528:DyaK1MXnvF2ntb4%3D
-
H Ishihara H Wang LR Drewes CB Wollheim 1999 Overexpression of monocarboxylate transporter and lactate dehydrogenase alters insulin secretory responses to pyruvate and lactate in beta cells J Clin Invest 104 1621 1629 10587526 10.1172/JCI7515 1:CAS:528:DyaK1MXnvF2ntb4%3D
-
(1999)
J Clin Invest
, vol.104
, pp. 1621-1629
-
-
Ishihara, H.1
Wang, H.2
Drewes, L.R.3
Wollheim, C.B.4
-
83
-
-
0001611540
-
Genetic, traumatic and environmental factors in the etiology of obesity
-
13100066 1:CAS:528:DyaG2cXotFyl
-
J Mayer 1953 Genetic, traumatic and environmental factors in the etiology of obesity Physiol Rev 33 472 508 13100066 1:CAS:528:DyaG2cXotFyl
-
(1953)
Physiol Rev
, vol.33
, pp. 472-508
-
-
Mayer, J.1
-
84
-
-
0019197915
-
A fall in blood glucose level precedes meal onset in free-feeding rats
-
DOI 10.1016/0149-7634(80)90041-X
-
J Louis-Sylvestre J Le Magnen 1980 Fall in blood glucose level precedes meal onset in free-feeding rats Neurosci Biobehav Rev 4 Suppl 1 13 15 6765504 10.1016/0149-7634(80)90041-X (Pubitemid 11190819)
-
(1980)
Neuroscience and Biobehavioral Reviews
, vol.4
, Issue.SUPPL. 1
, pp. 13-15
-
-
Louis-Sylvestre, J.1
Le Magnen, J.2
-
85
-
-
0022344825
-
On-line continuous measurement of blood glucose and meal pattern in free-feeding rats: The role of glucose in meal initiation
-
DOI 10.1016/0361-9230(85)90110-8
-
LA Campfield P Brandon FJ Smith 1985 On-line continuous measurement of blood glucose and meal pattern in free-feeding rats: the role of glucose in meal initiation Brain Res Bull 14 605 616 4027699 10.1016/0361-9230(85)90110-8 1:CAS:528:DyaL2MXlt1ahsr8%3D (Pubitemid 16239698)
-
(1985)
Brain Research Bulletin
, vol.14
, Issue.6
, pp. 605-616
-
-
Campfield, L.A.1
Brandon, P.2
Smith, F.J.3
-
86
-
-
0019505898
-
Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats
-
7193909 10.1126/science.7193909 1:CAS:528:DyaL3MXhsFGnsbk%3D
-
JD Davis D Wirtshafter KE Asin D Brief 1981 Sustained intracerebroventricular infusion of brain fuels reduces body weight and food intake in rats Science 212 81 83 7193909 10.1126/science.7193909 1:CAS:528:DyaL3MXhsFGnsbk%3D
-
(1981)
Science
, vol.212
, pp. 81-83
-
-
Davis, J.D.1
Wirtshafter, D.2
Asin, K.E.3
Brief, D.4
-
87
-
-
0019511895
-
D-Glucose infusions into the basal ventromedial hypothalamus and feeding
-
DOI 10.1016/0166-4328(81)90006-1
-
J Panksepp J Rossi 3rd 1981 D-glucose infusions into the basal ventromedial hypothalamus and feeding Behav Brain Res 3 381 392 6171296 10.1016/0166-4328(81)90006-1 1:CAS:528:DyaL3MXmtFygur0%3D (Pubitemid 11020301)
-
(1981)
Behavioural Brain Research
, vol.3
, Issue.3
, pp. 381-392
-
-
Panksepp, J.1
Rossi III, J.2
-
88
-
-
0022445038
-
D-glucose suppression of eating after intra-third ventricle infusion in rat
-
DOI 10.1016/0031-9384(86)90295-7
-
K Kurata K Fujimoto T Sakata H Etou K Fukagawa 1986 D-glucose suppression of eating after intra-third ventricle infusion in rat Physiol Behav 37 615 620 3749325 10.1016/0031-9384(86)90295-7 1:STN:280:DyaL28zhsVaktg%3D%3D (Pubitemid 16056628)
-
(1986)
Physiology and Behavior
, vol.37
, Issue.4
, pp. 615-620
-
-
Kurata, K.1
Fujimoto, K.2
Sakata, T.3
-
89
-
-
0017531067
-
Ingestive behavior after intracerebral and intracerebroventricular infusions of glucose and 2-deoxy-D-glucose
-
910934 1:CAS:528:DyaE2sXlslynsrs%3D
-
HR Berthoud GJ Mogenson 1977 Ingestive behavior after intracerebral and intracerebroventricular infusions of glucose and 2-deoxy-D-glucose Am J Physiol 233 R127 R133 910934 1:CAS:528:DyaE2sXlslynsrs%3D
-
(1977)
Am J Physiol
, vol.233
-
-
Berthoud, H.R.1
Mogenson, G.J.2
-
90
-
-
0016587571
-
Feeding induced by intracerebroventricular 2-deoxy-D-glucose in the rat
-
1200165 1:CAS:528:DyaE28XjvFejuw%3D%3D
-
RR Miselis AN Epstein 1975 Feeding induced by intracerebroventricular 2-deoxy-D-glucose in the rat Am J Physiol 229 1438 1447 1200165 1:CAS:528:DyaE28XjvFejuw%3D%3D
-
(1975)
Am J Physiol
, vol.229
, pp. 1438-1447
-
-
Miselis, R.R.1
Epstein, A.N.2
-
91
-
-
0033976228
-
Localization of hindbrain glucoreceptive sites controlling food intake and blood glucose
-
DOI 10.1016/S0006-8993(99)02327-6, PII S0006899399023276
-
S Ritter TT Dinh Y Zhang 2000 Localization of hindbrain glucoreceptive sites controlling food intake and blood glucose Brain Res 856 37 47 10677609 10.1016/S0006-8993(99)02327-6 1:CAS:528:DC%2BD3cXhtFantLg%3D (Pubitemid 30085509)
-
(2000)
Brain Research
, vol.856
, Issue.1-2
, pp. 37-47
-
-
Ritter, S.1
Dinh, T.T.2
Zhang, Y.3
-
92
-
-
0035795199
-
Immunotoxic destruction of distinct catecholamine subgroups produces selective impairment of glucoregulatory responses and neuronal activation
-
DOI 10.1002/cne.1097
-
S Ritter K Bugarith TT Dinh 2001 Immunotoxic destruction of distinct catecholamine subgroups produces selective impairment of glucoregulatory responses and neuronal activation J Comp Neurol 432 197 216 11241386 10.1002/cne.1097 1:CAS:528:DC%2BD3MXitVKnt7s%3D (Pubitemid 32187012)
-
(2001)
Journal of Comparative Neurology
, vol.432
, Issue.2
, pp. 197-216
-
-
Ritter, S.1
Bugarith, K.2
Dinh, T.T.3
-
93
-
-
0037227401
-
Immunolesion of norepinephrine and epinephrine afferents to medial hypothalamus alters basal and 2-deoxy-D-glucose-induced neuropeptide Y and agouti gene-related protein messenger ribonucleic acid expression in the arcuate nucleus
-
DOI 10.1210/en.2002-220659
-
GS Fraley S Ritter 2003 Immunolesion of norepinephrine and epinephrine afferents to medial hypothalamus alters basal and 2-deoxy-D-glucose-induced neuropeptide Y and agouti gene-related protein messenger ribonucleic acid expression in the arcuate nucleus Endocrinology 144 75 83 12488332 10.1210/en.2002-220659 1:CAS:528:DC%2BD3sXhtFSgtA%3D%3D (Pubitemid 36076095)
-
(2003)
Endocrinology
, vol.144
, Issue.1
, pp. 75-83
-
-
Fraley, G.S.1
Ritter, S.2
-
94
-
-
27344431720
-
NPY/AgRP neurons are essentials for feeding in adult mice but can be ablated in neonates
-
DOI 10.1126/science.1115524
-
S Luquet FA Perez TS Hnasko RD Palmiter 2005 NPY/AgRP neurons are essential for feeding in adult mice but can be ablated in neonates Science 310 683 685 16254186 10.1126/science.1115524 1:CAS:528:DC%2BD2MXhtFChsLjI (Pubitemid 41528162)
-
(2005)
Science
, vol.310
, Issue.5748
, pp. 683-685
-
-
Luquet, S.1
Perez, F.A.2
Hnasko, T.S.3
Palmiter, R.D.4
-
95
-
-
33846597193
-
NPY/AgRP neurons are not essential for feeding responses to glucoprivation
-
DOI 10.1016/j.peptides.2006.08.036, PII S0196978106005304, NPY and Cohorts in Human Disease
-
S Luquet CT Phillips RD Palmiter 2007 NPY/AgRP neurons are not essential for feeding responses to glucoprivation Peptides 28 214 225 17194499 10.1016/j.peptides.2006.08.036 1:CAS:528:DC%2BD2sXhtlagu7w%3D (Pubitemid 46176250)
-
(2007)
Peptides
, vol.28
, Issue.2
, pp. 214-225
-
-
Luquet, S.1
Phillips, C.T.2
Palmiter, R.D.3
-
96
-
-
0142067094
-
Intracerebroventricular administration of antisense oligodeoxynucleotide against GLUT2 glucose transporter mRNA reduces food intake, body weight change and glucoprivic feeding response in rats
-
9446857 1:CAS:528:DyaK1cXhtVCgsbg%3D
-
HZ Wan MG Hulsey RJ Martin 1998 Intracerebroventricular administration of antisense oligodeoxynucleotide against GLUT2 glucose transporter mRNA reduces food intake, body weight change and glucoprivic feeding response in rats J Nutr 128 287 291 9446857 1:CAS:528:DyaK1cXhtVCgsbg%3D
-
(1998)
J Nutr
, vol.128
, pp. 287-291
-
-
Wan, H.Z.1
Hulsey, M.G.2
Martin, R.J.3
-
97
-
-
33745322219
-
Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding
-
DOI 10.2337/diabetes.55.04.06.db05-1386
-
I Bady N Marty M Dallaporta M Emery J Gyger D Tarussio M Foretz B Thorens 2006 Evidence from glut2-null mice that glucose is a critical physiological regulator of feeding Diabetes 55 988 995 16567520 10.2337/diabetes.55.04.06. db05-1386 1:CAS:528:DC%2BD28XjsVGmtL8%3D (Pubitemid 44100173)
-
(2006)
Diabetes
, vol.55
, Issue.4
, pp. 988-995
-
-
Bady, I.1
Marty, N.2
Dallaporta, M.3
Emery, M.4
Gyger, J.5
Tarussio, D.6
Foretz, M.7
Thorens, B.8
-
98
-
-
45549102127
-
Genetic variant in the glucose transporter type 2 is associated with higher intakes of sugars in two distinct populations
-
DOI 10.1152/physiolgenomics.00148.2007
-
KM Eny TM Wolever B Fontaine-Bisson A El-Sohemy 2008 Genetic variant in the glucose transporter type 2 is associated with higher intakes of sugars in two distinct populations Physiol Genomics 33 355 360 18349384 10.1152/physiolgenomics.00148.2007 1:CAS:528:DC%2BD1cXps1antb4%3D (Pubitemid 352755737)
-
(2008)
Physiological Genomics
, vol.33
, Issue.3
, pp. 355-360
-
-
Eny, K.M.1
Wolever, T.M.S.2
Fontaine-Bisson, B.3
El-Sohemy, A.4
-
99
-
-
5044229137
-
Immunocytochemical localization of the glucose transporter 2 (GLUT2) in the adult rat brain. II. Electron microscopic study
-
DOI 10.1016/j.jchemneu.2004.06.002, PII S0891061804000766
-
M Arluison M Quignon B Thorens C Leloup L Penicaud 2004 Immunocytochemical localization of the glucose transporter 2 (GLUT2) in the adult rat brain. II. Electron microscopic study J Chem Neuroanat 28 137 146 15482900 10.1016/j.jchemneu.2004.06.002 1:CAS:528:DC%2BD2cXos1ertr8%3D (Pubitemid 39336525)
-
(2004)
Journal of Chemical Neuroanatomy
, vol.28
, Issue.3
, pp. 137-146
-
-
Arluison, M.1
Quignon, M.2
Thorens, B.3
Leloup, C.4
Penicaud, L.5
-
100
-
-
0038582455
-
Distribution of glucokinase, glucose transporter GLUT2, sulfonylurea receptor-1, glucagon-like peptide-1 receptor and neuropeptide Y messenger RNAs in rat brain by quantitative real time RT-PCR
-
DOI 10.1016/S0169-328X(03)00125-6
-
B Li X Xi DS Roane DH Ryan RJ Martin 2003 Distribution of glucokinase, glucose transporter GLUT2, sulfonylurea receptor-1, glucagon-like peptide-1 receptor and neuropeptide Y messenger RNAs in rat brain by quantitative real-time RT-PCR Brain Res Mol Brain Res 113 139 142 12750016 10.1016/S0169-328X(03)00125-6 1:CAS:528:DC%2BD3sXjs1Clu7w%3D (Pubitemid 36579076)
-
(2003)
Molecular Brain Research
, vol.113
, Issue.1-2
, pp. 139-142
-
-
Li, B.1
Xi, X.2
Roane, D.S.3
Ryan, D.H.4
Martin, R.J.5
-
101
-
-
0042303943
-
Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing
-
DOI 10.1046/j.1471-4159.2003.01892.x
-
MA Garcia C Millan C Balmaceda-Aguilera T Castro P Pastor H Montecinos K Reinicke F Zuniga JC Vera SA Onate F Nualart 2003 Hypothalamic ependymal-glial cells express the glucose transporter GLUT2, a protein involved in glucose sensing J Neurochem 86 709 724 12859684 10.1046/j.1471-4159.2003.01892.x 1:CAS:528:DC%2BD3sXlvF2nurk%3D (Pubitemid 36897451)
-
(2003)
Journal of Neurochemistry
, vol.86
, Issue.3
, pp. 709-724
-
-
De Los Angeles Garcia, M.1
Millan, C.2
Balmaceda-Aguilera, C.3
Castro, T.4
Pastor, P.5
Montecinos, H.6
Reinicke, K.7
Zuniga, F.8
Vera, J.C.9
Onate, S.A.10
Nualart, F.11
-
102
-
-
0034463846
-
Localization of glucokinase-like immunoreactivity in the rat lower brain stem: For possible location of brain glucose-sensing mechanisms
-
DOI 10.1210/en.141.1.375
-
F Maekawa Y Toyoda N Torii I Miwa RC Thompson DL Foster S Tsukahara H Tsukamura K Maeda 2000 Localization of glucokinase-like immunoreactivity in the rat lower brain stem: for possible location of brain glucose-sensing mechanisms Endocrinology 141 375 384 10614660 10.1210/en.141.1.375 1:CAS:528:DC%2BD3cXkslOl (Pubitemid 32260380)
-
(2000)
Endocrinology
, vol.141
, Issue.1
, pp. 375-384
-
-
Maekawa, F.1
Toyoda, Y.2
Torii, N.3
Miwa, I.4
Thompson, R.C.5
Foster, D.L.6
Tsukahara, S.7
Tsukamura, H.8
Maeda, K.-I.9
-
103
-
-
0035805090
-
Co-localization of GLUT1 and GLUT4 in the blood-brain barrier of the rat ventromedial hypothalamus
-
DOI 10.1016/S0006-8993(01)02184-9, PII S0006899301021849
-
C Ngarmukos EL Baur AK Kumagai 2001 Co-localization of GLUT1 and GLUT4 in the blood-brain barrier of the rat ventromedial hypothalamus Brain Res 900 1 8 11325341 10.1016/S0006-8993(01)02184-9 1:CAS:528:DC%2BD3MXivFeit7c%3D (Pubitemid 32452259)
-
(2001)
Brain Research
, vol.900
, Issue.1
, pp. 1-8
-
-
Ngarmukos, C.1
Baur, E.L.2
Kumagai, A.K.3
-
104
-
-
33947400627
-
Glucokinase regulates reproductive function, glucocorticoid secretion, food intake, and hypothalamic gene expression
-
DOI 10.1210/en.2006-1312
-
XJ Yang J Mastaitis T Mizuno CV Mobbs 2007 Glucokinase regulates reproductive function, glucocorticoid secretion, food intake, and hypothalamic gene expression Endocrinology 148 1928 1932 17218412 10.1210/en.2006-1312 1:CAS:528:DC%2BD2sXjvVOhtbY%3D (Pubitemid 46457103)
-
(2007)
Endocrinology
, vol.148
, Issue.4
, pp. 1928-1932
-
-
Yang, X.-J.1
Mastaitis, J.2
Mizuno, T.3
Mobbs, C.V.4
-
105
-
-
33745819212
-
ATP channel activation and leads to diet-sensitive obesity
-
DOI 10.1172/JCI27123
-
L Plum X Ma B Hampel N Balthasar R Coppari H Munzberg M Shanabrough D Burdakov E Rother R Janoschek J Alber BF Belgardt L Koch J Seibler F Schwenk C Fekete A Suzuki TW Mak W Krone TL Horvath FM Ashcroft JC Bruning 2006 Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity J Clin Invest 116 1886 1901 16794735 10.1172/JCI27123 1:CAS:528:DC%2BD28XmvV2ltbY%3D (Pubitemid 44033313)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1886-1901
-
-
Plum, L.1
Ma, X.2
Hampel, B.3
Balthasar, N.4
Coppari, R.5
Munzberg, H.6
Shanabrough, M.7
Burdakov, D.8
Rother, E.9
Janoschek, R.10
Alber, J.11
Belgardt, B.F.12
Koch, L.13
Seibler, J.14
Schwenk, F.15
Fekete, C.16
Suzuki, A.17
Mak, T.W.18
Krone, W.19
Horvath, T.L.20
Ashcroft, F.M.21
Bruning, J.C.22
more..
-
106
-
-
0032491319
-
PIP2 and PIP as determinants for ATP inhibition of KATP channels
-
9804555 10.1126/science.282.5391.1141 1:CAS:528:DyaK1cXntleisrY%3D
-
T Baukrowitz U Schulte D Oliver S Herlitze T Krauter SJ Tucker JP Ruppersberg B Fakler 1998 PIP2 and PIP as determinants for ATP inhibition of KATP channels Science 282 1141 1144 9804555 10.1126/science.282.5391.1141 1:CAS:528:DyaK1cXntleisrY%3D
-
(1998)
Science
, vol.282
, pp. 1141-1144
-
-
Baukrowitz, T.1
Schulte, U.2
Oliver, D.3
Herlitze, S.4
Krauter, T.5
Tucker, S.J.6
Ruppersberg, J.P.7
Fakler, B.8
-
108
-
-
0032491439
-
Membrane phospholipid control of nucleotide sensitivity of KATP channels
-
9804554 10.1126/science.282.5391.1138 1:CAS:528:DyaK1cXntleju7o%3D
-
SL Shyng CG Nichols 1998 Membrane phospholipid control of nucleotide sensitivity of KATP channels Science 282 1138 1141 9804554 10.1126/science.282. 5391.1138 1:CAS:528:DyaK1cXntleju7o%3D
-
(1998)
Science
, vol.282
, pp. 1138-1141
-
-
Shyng, S.L.1
Nichols, C.G.2
-
109
-
-
12944261926
-
ATP channel activation
-
DOI 10.1186/1471-2202-5-54
-
S Mirshamsi HA Laidlaw K Ning E Anderson LA Burgess A Gray C Sutherland ML Ashford 2004 Leptin and insulin stimulation of signalling pathways in arcuate nucleus neurones: PI3K-dependent actin reorganization and KATP channel activation BMC Neurosci 5 54 15581426 10.1186/1471-2202-5-54 1:CAS:528:DC%2BD2MXhsFWisr4%3D (Pubitemid 40177027)
-
(2004)
BMC Neuroscience
, vol.5
, pp. 54
-
-
Mirshamsi, S.1
Laidlaw, H.A.2
Ning, K.3
Anderson, E.4
Burgess, L.A.5
Gray, A.6
Sutherland, C.7
Ashford, M.L.J.8
-
110
-
-
34547651092
-
AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons
-
DOI 10.1172/JCI31516
-
M Claret MA Smith RL Batterham C Selman AI Choudhury LG Fryer M Clements H Al-Qassab H Heffron AW Xu JR Speakman GS Barsh B Viollet S Vaulont ML Ashford D Carling DJ Withers 2007 AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons J Clin Invest 117 2325 2336 17671657 10.1172/JCI31516 1:CAS:528:DC%2BD2sXoslOnsLo%3D (Pubitemid 47219577)
-
(2007)
Journal of Clinical Investigation
, vol.117
, Issue.8
, pp. 2325-2336
-
-
Claret, M.1
Smith, M.A.2
Batterham, R.L.3
Selman, C.4
Choudhury, A.I.5
Fryer, L.G.D.6
Clements, M.7
Al-Qassab, H.8
Heffron, H.9
Xu, A.W.10
Speakman, J.R.11
Barsh, G.S.12
Viollet, B.13
Vaulont, S.14
Ashford, M.L.J.15
Carling, D.16
Withers, D.J.17
-
111
-
-
0023579692
-
Glucose-induced norepinephrine levels and obesity resistance
-
3307459 1:CAS:528:DyaL2sXmtlChtL8%3D
-
BE Levin AC Sullivan 1987 Glucose-induced norepinephrine levels and obesity resistance Am J Physiol 253 R475 R481 3307459 1:CAS:528: DyaL2sXmtlChtL8%3D
-
(1987)
Am J Physiol
, vol.253
-
-
Levin, B.E.1
Sullivan, A.C.2
-
112
-
-
0023198344
-
Glucose, insulin and sympathoadrenal activation
-
DOI 10.1016/0165-1838(87)90152-4
-
BE Levin AC Sullivan 1987 Glucose, insulin and sympathoadrenal activation J Auton Nerv Syst 20 233 242 3320167 10.1016/0165-1838(87)90152-4 1:CAS:528:DyaL1cXmvFCmtA%3D%3D (Pubitemid 17160154)
-
(1987)
Journal of the Autonomic Nervous System
, vol.20
, Issue.3
, pp. 233-242
-
-
Levin, B.E.1
Sullivan, A.C.2
-
113
-
-
0021739077
-
Thermic effect of glucose in man. Obligatory and facultative thermogenesis
-
6389598 10.1172/JCI111573 1:CAS:528:DyaL2MXhvVaitg%3D%3D
-
KJ Acheson E Ravussin J Wahren E Jequier 1984 Thermic effect of glucose in man. Obligatory and facultative thermogenesis J Clin Invest 74 1572 1580 6389598 10.1172/JCI111573 1:CAS:528:DyaL2MXhvVaitg%3D%3D
-
(1984)
J Clin Invest
, vol.74
, pp. 1572-1580
-
-
Acheson, K.J.1
Ravussin, E.2
Wahren, J.3
Jequier, E.4
-
114
-
-
0024370868
-
Glucose-induced sympathetic activation in obesity-prone and resistant rats
-
2744935 1:STN:280:DyaL1MzgslOnsg%3D%3D
-
BE Levin AC Sullivan 1989 Glucose-induced sympathetic activation in obesity-prone and resistant rats Int J Obes 13 235 246 2744935 1:STN:280:DyaL1MzgslOnsg%3D%3D
-
(1989)
Int J Obes
, vol.13
, pp. 235-246
-
-
Levin, B.E.1
Sullivan, A.C.2
-
115
-
-
0026350902
-
Glucose increases rat plasma norepinephrine levels by direct action on the brain
-
1750559 1:CAS:528:DyaK38Xns12ktw%3D%3D
-
BE Levin 1991 Glucose increases rat plasma norepinephrine levels by direct action on the brain Am J Physiol 261 R1351 R1357 1750559 1:CAS:528:DyaK38Xns12ktw%3D%3D
-
(1991)
Am J Physiol
, vol.261
-
-
Levin, B.E.1
-
116
-
-
0032547892
-
Reduced glucose-induced neuronal activation in the hypothalamus of diet- induced obese rats
-
DOI 10.1016/S0006-8993(98)00839-7, PII S0006899398008397
-
BE Levin EK Govek AA Dunn-Meynell 1998 Reduced glucose-induced neuronal activation in the hypothalamus of diet-induced obese rats Brain Res 808 317 319 9767180 10.1016/S0006-8993(98)00839-7 1:CAS:528:DyaK1cXmt1ems70%3D (Pubitemid 29009566)
-
(1998)
Brain Research
, vol.808
, Issue.2
, pp. 317-319
-
-
Levin, B.E.1
Govek, E.K.2
Dunn-Meynell, A.A.3
-
117
-
-
0023213629
-
The effect of intrahypothalamic injections of glucose on sympathetic efferent firing rate
-
DOI 10.1016/0361-9230(87)90128-6
-
T Sakaguchi GA Bray 1987 The effect of intrahypothalamic injections of glucose on sympathetic efferent firing rate Brain Res Bull 18 591 595 3607527 10.1016/0361-9230(87)90128-6 1:CAS:528:DyaL2sXkslGit78%3D (Pubitemid 17121629)
-
(1987)
Brain Research Bulletin
, vol.18
, Issue.5
, pp. 591-595
-
-
Sakaguchi, T.1
Bray, G.A.2
-
118
-
-
0024162399
-
Sympathetic activity following paraventricular injections of glucose and insulin
-
DOI 10.1016/0361-9230(88)90115-3
-
T Sakaguchi GA Bray 1988 Sympathetic activity following paraventricular injections of glucose and insulin Brain Res Bull 21 25 29 3064881 10.1016/0361-9230(88)90115-3 1:CAS:528:DyaL1cXlsVOjurg%3D (Pubitemid 19268442)
-
(1988)
Brain Research Bulletin
, vol.21
, Issue.1
, pp. 25-29
-
-
Sakaguchi, T.1
Bray, G.A.2
-
119
-
-
45549098243
-
Neurocircuits integrating hormone and nutrient signaling in control of glucose metabolism
-
18285523 10.1152/ajpendo.00685.2007 1:CAS:528:DC%2BD1cXlvFCjurs%3D
-
E Rother AC Konner JC Bruning 2008 Neurocircuits integrating hormone and nutrient signaling in control of glucose metabolism Am J Physiol Endocrinol Metab 294 E810 E816 18285523 10.1152/ajpendo.00685.2007 1:CAS:528: DC%2BD1cXlvFCjurs%3D
-
(2008)
Am J Physiol Endocrinol Metab
, vol.294
-
-
Rother, E.1
Konner, A.C.2
Bruning, J.C.3
-
120
-
-
17844379717
-
ATP channels control hepatic glucose production
-
DOI 10.1038/nature03439
-
A Pocai TK Lam R Gutierrez-Juarez S Obici GJ Schwartz J Bryan L Aguilar-Bryan L Rossetti 2005 Hypothalamic K(ATP) channels control hepatic glucose production Nature 434 1026 1031 15846348 10.1038/nature03439 1:CAS:528:DC%2BD2MXjsVequrk%3D (Pubitemid 40586051)
-
(2005)
Nature
, vol.434
, Issue.7036
, pp. 1026-1031
-
-
Pocal, A.1
Lam, T.K.T.2
Gutierrez-Juarez, R.3
Obici, S.4
Schwartz, G.J.5
Bryan, J.6
Aguilar-Bryan, L.7
Rossetti, L.8
-
121
-
-
77249140630
-
Hypothalamic sensing of circulating lactate regulates glucose production
-
A Kokorovic GW Cheung L Rossetti TK Lam 2008 Hypothalamic sensing of circulating lactate regulates glucose production J Cell Mol Med 57 594 605
-
(2008)
J Cell Mol Med
, vol.57
, pp. 594-605
-
-
Kokorovic, A.1
Cheung, G.W.2
Rossetti, L.3
Lam, T.K.4
-
122
-
-
33846988243
-
Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins
-
17273170 10.1038/nm1540 1:CAS:528:DC%2BD2sXhsVykur4%3D
-
TK Lam R Gutierrez-Juarez A Pocai S Bhanot P Tso GJ Schwartz L Rossetti 2007 Brain glucose metabolism controls the hepatic secretion of triglyceride-rich lipoproteins Nat Med 13 171 180 17273170 10.1038/nm1540 1:CAS:528:DC%2BD2sXhsVykur4%3D
-
(2007)
Nat Med
, vol.13
, pp. 171-180
-
-
Lam, T.K.1
Gutierrez-Juarez, R.2
Pocai, A.3
Bhanot, S.4
Tso, P.5
Schwartz, G.J.6
Rossetti, L.7
-
123
-
-
2442710176
-
Diverse causes of hypoglycemia-associated autonomic failure in diabetes
-
DOI 10.1056/NEJMra031354
-
PE Cryer 2004 Diverse causes of hypoglycemia-associated autonomic failure in diabetes N Engl J Med 350 2272 2279 15163777 10.1056/NEJMra031354 1:CAS:528:DC%2BD2cXksVeht78%3D (Pubitemid 38669210)
-
(2004)
New England Journal of Medicine
, vol.350
, Issue.22
-
-
Cryer, P.E.1
-
124
-
-
0026019648
-
Hierarchy of glycemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction
-
1987794 1:CAS:528:DyaK3MXhsVSrtLY%3D
-
A Mitrakou C Ryan T Veneman M Mokan T Jenssen I Kiss J Durrant P Cryer J Gerich 1991 Hierarchy of glycemic thresholds for counterregulatory hormone secretion, symptoms, and cerebral dysfunction Am J Physiol 260 E67 E74 1987794 1:CAS:528:DyaK3MXhsVSrtLY%3D
-
(1991)
Am J Physiol
, vol.260
-
-
Mitrakou, A.1
Ryan, C.2
Veneman, T.3
Mokan, M.4
Jenssen, T.5
Kiss, I.6
Durrant, J.7
Cryer, P.8
Gerich, J.9
-
125
-
-
2642593026
-
Autonomic mediation of glucagon secretion during hypoglycemia: Implications for impaired α-cell responses in type 1 diabetes
-
DOI 10.2337/diabetes.47.7.995
-
GJ Taborsky Jr B Ahren PJ Havel 1998 Autonomic mediation of glucagon secretion during hypoglycemia: implications for impaired alpha-cell responses in type 1 diabetes Diabetes 47 995 1005 9648820 10.2337/diabetes.47.7.995 1:CAS:528:DyaK1cXkt1ajtrw%3D (Pubitemid 28294539)
-
(1998)
Diabetes
, vol.47
, Issue.7
, pp. 995-1005
-
-
Taborsky Jr., G.J.1
Ahren, B.2
Havel, P.J.3
-
126
-
-
0024520153
-
Role of brain in counterregulation of insulin-induced hypoglycemia in dogs
-
2642436 10.2337/diabetes.38.1.7 1:CAS:528:DyaL1MXpt12lug%3D%3D
-
DW Biggers SR Myers D Neal R Stinson NB Cooper JB Jaspan PE Williams AD Cherrington RT Frizzell 1989 Role of brain in counterregulation of insulin-induced hypoglycemia in dogs Diabetes 38 7 16 2642436 10.2337/diabetes.38.1.7 1:CAS:528:DyaL1MXpt12lug%3D%3D
-
(1989)
Diabetes
, vol.38
, pp. 7-16
-
-
Biggers, D.W.1
Myers, S.R.2
Neal, D.3
Stinson, R.4
Cooper, N.B.5
Jaspan, J.B.6
Williams, P.E.7
Cherrington, A.D.8
Frizzell, R.T.9
-
127
-
-
0027327113
-
Counterregulation during hypoglycemia is directed by widespread brain regions
-
8349036 10.2337/diabetes.42.9.1253 1:STN:280:DyaK3szltFOmtQ%3D%3D
-
RT Frizzell EM Jones SN Davis DW Biggers SR Myers CC Connolly DW Neal JB Jaspan AD Cherrington 1993 Counterregulation during hypoglycemia is directed by
-
(1993)
Diabetes
, vol.42
, pp. 1253-1261
-
-
Frizzell, R.T.1
Jones, E.M.2
Davis, S.N.3
Biggers, D.W.4
Myers, S.R.5
Connolly, C.C.6
Neal, D.W.7
Jaspan, J.B.8
Cherrington, A.D.9
-
128
-
-
0028931891
-
Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release
-
7859938 10.2337/diabetes.44.2.180 1:CAS:528:DyaK2MXjtlCksL4%3D
-
WP Borg RS Sherwin MJ During MA Borg GI Shulman 1995 Local ventromedial hypothalamus glucopenia triggers counterregulatory hormone release Diabetes 44 180 184 7859938 10.2337/diabetes.44.2.180 1:CAS:528:DyaK2MXjtlCksL4%3D
-
(1995)
Diabetes
, vol.44
, pp. 180-184
-
-
Borg, W.P.1
Sherwin, R.S.2
During, M.J.3
Borg, M.A.4
Shulman, G.I.5
-
129
-
-
0031038124
-
Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats
-
9006005 10.1172/JCI119165 1:CAS:528:DyaK2sXntFSgsA%3D%3D
-
MA Borg RS Sherwin WP Borg WV Tamborlane GI Shulman 1997 Local ventromedial hypothalamus glucose perfusion blocks counterregulation during systemic hypoglycemia in awake rats J Clin Invest 99 361 365 9006005 10.1172/JCI119165 1:CAS:528:DyaK2sXntFSgsA%3D%3D
-
(1997)
J Clin Invest
, vol.99
, pp. 361-365
-
-
Borg, M.A.1
Sherwin, R.S.2
Borg, W.P.3
Tamborlane, W.V.4
Shulman, G.I.5
-
130
-
-
33745327159
-
A receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo- pituitary-adrenal response to hypoglycemia
-
DOI 10.2337/diabetes.55.04.06.db05-0958
-
O Chan W Zhu Y Ding RJ McCrimmon RS Sherwin 2006 Blockade of GABA(A) receptors in the ventromedial hypothalamus further stimulates glucagon and sympathoadrenal but not the hypothalamo-pituitary-adrenal response to hypoglycemia Diabetes 55 1080 1087 16567532 10.2337/diabetes.55.04.06.db05-0958 1:CAS:528:DC%2BD28XjsVGmtb0%3D (Pubitemid 44100185)
-
(2006)
Diabetes
, vol.55
, Issue.4
, pp. 1080-1087
-
-
Chan, O.1
Zhu, W.2
Ding, Y.3
McCrimmon, R.J.4
Sherwin, R.S.5
-
131
-
-
34047114378
-
+ channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia
-
DOI 10.2337/db06-1102
-
O Chan M Lawson W Zhu JL Beverly RS Sherwin 2007 ATP-sensitive K(+) channels regulate the release of GABA in the ventromedial hypothalamus during hypoglycemia Diabetes 56 1120 1126 17251273 10.2337/db06-1102 1:CAS:528:DC%2BD2sXktFChu78%3D (Pubitemid 46525084)
-
(2007)
Diabetes
, vol.56
, Issue.4
, pp. 1120-1126
-
-
Chan, O.1
Lawson, M.2
Zhu, W.3
Beverly, J.L.4
Sherwin, R.S.5
-
132
-
-
48449083962
-
Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory responses after antecedent hypoglycemia
-
18375441 10.2337/db07-1559 1:CAS:528:DC%2BD1cXlvVKjtbg%3D
-
O Chan H Cheng R Herzog D Czyzyk W Zhu A Wang RJ McCrimmon MR Seashore RS Sherwin 2008 Increased GABAergic tone in the ventromedial hypothalamus contributes to suppression of counterregulatory responses after antecedent hypoglycemia Diabetes 57 1363 1370 18375441 10.2337/db07-1559 1:CAS:528:DC%2BD1cXlvVKjtbg%3D
-
(2008)
Diabetes
, vol.57
, pp. 1363-1370
-
-
Chan, O.1
Cheng, H.2
Herzog, R.3
Czyzyk, D.4
Zhu, W.5
Wang, A.6
McCrimmon, R.J.7
Seashore, M.R.8
Sherwin, R.S.9
-
133
-
-
34247616021
-
Synaptic Glutamate Release by Ventromedial Hypothalamic Neurons Is Part of the Neurocircuitry that Prevents Hypoglycemia
-
DOI 10.1016/j.cmet.2007.04.001, PII S1550413107000964
-
Q Tong C Ye RJ McCrimmon H Dhillon B Choi MD Kramer J Yu Z Yang LM Christiansen CE Lee CS Choi JM Zigman GI Shulman RS Sherwin JK Elmquist BB Lowell 2007 Synaptic glutamate release by ventromedial hypothalamic neurons is part of the neurocircuitry that prevents hypoglycemia Cell Metab 5 383 393 17488640 10.1016/j.cmet.2007.04.001 1:CAS:528:DC%2BD2sXmt1ajsr4%3D (Pubitemid 46667758)
-
(2007)
Cell Metabolism
, vol.5
, Issue.5
, pp. 383-393
-
-
Tong, Q.1
Ye, C.2
McCrimmon, R.J.3
Dhillon, H.4
Choi, B.5
Kramer, M.D.6
Yu, J.7
Yang, Z.8
Christiansen, L.M.9
Lee, C.E.10
Choi, C.S.11
Zigman, J.M.12
Shulman, G.I.13
Sherwin, R.S.14
Elmquist, J.K.15
Lowell, B.B.16
-
134
-
-
63249134830
-
Small decrements in systemic glucose provoke increases in hypothalamic blood flow prior to the release of counterregulatory hormones
-
19017765 10.2337/db08-1224 1:CAS:528:DC%2BD1MXhslertr8%3D
-
KA Page J Arora M Qiu R Relwani RT Constable RS Sherwin 2009 Small decrements in systemic glucose provoke increases in hypothalamic blood flow prior to the release of counterregulatory hormones Diabetes 58 448 452 19017765 10.2337/db08-1224 1:CAS:528:DC%2BD1MXhslertr8%3D
-
(2009)
Diabetes
, vol.58
, pp. 448-452
-
-
Page, K.A.1
Arora, J.2
Qiu, M.3
Relwani, R.4
Constable, R.T.5
Sherwin, R.S.6
-
135
-
-
0019794835
-
Glucoreceptors controlling feeding and blood glucose: Location in the hindbrain
-
6264602 10.1126/science.6264602 1:CAS:528:DyaL3MXkslOmsrk%3D
-
RC Ritter PG Slusser S Stone 1981 Glucoreceptors controlling feeding and blood glucose: location in the hindbrain Science 213 451 452 6264602 10.1126/science.6264602 1:CAS:528:DyaL3MXkslOmsrk%3D
-
(1981)
Science
, vol.213
, pp. 451-452
-
-
Ritter, R.C.1
Slusser, P.G.2
Stone, S.3
-
136
-
-
0032517174
-
Subgroups of hindbrain catecholamine neurons are selectively activated by 2-deoxy-D-glucose induced metabolic challenge
-
DOI 10.1016/S0006-8993(98)00655-6, PII S0006899398006556
-
S Ritter I Llewellyn-Smith TT Dinh 1998 Subgroups of hindbrain catecholamine neurons are selectively activated by 2-deoxy-D-glucose induced metabolic challenge Brain Res 805 41 54 9733914 10.1016/S0006-8993(98)00655-6 1:CAS:528:DyaK1cXlsl2gtLk%3D (Pubitemid 29005121)
-
(1998)
Brain Research
, vol.805
, Issue.1-2
, pp. 41-54
-
-
Ritter, S.1
Llewellyn-Smith, I.2
Dinh, T.T.3
-
137
-
-
0034604731
-
Transgenic reexpression of GLUT1 or GLUT2 in pancreatic β cells rescues GLUT2-null mice from early death and restores normal glucose-stimulated insulin secretion
-
DOI 10.1074/jbc.M002908200
-
B Thorens MT Guillam F Beermann R Burcelin M Jaquet 2000 Transgenic reexpression of GLUT1 or GLUT2 in pancreatic beta cells rescues GLUT2-null mice from early death and restores normal glucose-stimulated insulin secretion J Biol Chem 275 23751 23758 10823833 10.1074/jbc.M002908200 1:CAS:528: DC%2BD3cXls12murY%3D (Pubitemid 30627456)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.31
, pp. 23751-23758
-
-
Thorens, B.1
Guillam, M.-T.2
Beermann, F.3
Burcelin, R.4
Jaquet, M.5
-
138
-
-
0029915866
-
In vivo labeling of brain phospholipids by long-chain fatty acids: Relation to turnover and function
-
8729102 10.1007/BF02637059 1:CAS:528:DyaK28XhvVSht7g%3D
-
SI Rapoport 1996 In vivo labeling of brain phospholipids by long-chain fatty acids: relation to turnover and function Lipids 31 Suppl S97 S101 8729102 10.1007/BF02637059 1:CAS:528:DyaK28XhvVSht7g%3D
-
(1996)
Lipids
, vol.31
, Issue.SUPPL
-
-
Rapoport, S.I.1
-
139
-
-
0023636723
-
14C]palmitate between oxidative and synthetic pathways
-
DOI 10.1111/j.1471-4159.1987.tb01021.x
-
JC Miller JM Gnaedinger SI Rapoport 1987 Utilization of plasma fatty acid in rat brain: distribution of [14C]palmitate between oxidative and synthetic pathways J Neurochem 49 1507 1514 2889801 10.1111/j.1471-4159.1987.tb01021.x 1:CAS:528:DyaL2sXmtFGgsbk%3D (Pubitemid 17161373)
-
(1987)
Journal of Neurochemistry
, vol.49
, Issue.5
, pp. 1507-1514
-
-
Miller, J.C.1
Gnaedinger, J.M.2
Rapoport, S.I.3
-
140
-
-
0036515176
-
Long-chain polyunsaturated fatty acid accretion in brain
-
11844978 10.1097/00075197-200203000-00003 1:CAS:528:DC%2BD38XitVKmsr4%3D
-
K Qi M Hall RJ Deckelbaum 2002 Long-chain polyunsaturated fatty acid accretion in brain Curr Opin Clin Nutr Metab Care 5 133 138 11844978 10.1097/00075197-200203000-00003 1:CAS:528:DC%2BD38XitVKmsr4%3D
-
(2002)
Curr Opin Clin Nutr Metab Care
, vol.5
, pp. 133-138
-
-
Qi, K.1
Hall, M.2
Deckelbaum, R.J.3
-
141
-
-
0034912915
-
In vivo fatty acid incorporation into brain phospholipids in relation to plasma availability, signal transduction and membrane remodeling
-
DOI 10.1385/JMN:16:2-3:243
-
SI Rapoport 2001 In vivo fatty acid incorporation into brain phosholipids in relation to plasma availability, signal transduction and membrane remodeling J Mol Neurosci 16 243 261 11478380 10.1385/JMN:16:2-3:243 1:CAS:528: DC%2BD3MXltlarsrg%3D discussion 279-284 (Pubitemid 32664786)
-
(2001)
Journal of Molecular Neuroscience
, vol.16
, Issue.2-3
, pp. 243-261
-
-
Rapoport, S.I.1
-
142
-
-
0016814940
-
Effect of free fatty acid on the rat lateral hypothalamic neurons
-
1135293 10.1016/0031-9384(75)90015-3 1:CAS:528:DyaE2MXksFKhtbY%3D
-
Y Oomura T Nakamura M Sugimori Y Yamada 1975 Effect of free fatty acid on the rat lateral hypothalamic neurons Physiol Behav 14 483 486 1135293 10.1016/0031-9384(75)90015-3 1:CAS:528:DyaE2MXksFKhtbY%3D
-
(1975)
Physiol Behav
, vol.14
, pp. 483-486
-
-
Oomura, Y.1
Nakamura, T.2
Sugimori, M.3
Yamada, Y.4
-
143
-
-
12144268025
-
Beta oxidation in the brain is required for the effects of non-esterified fatty acids on glucose-induced insulin secretion in rats
-
DOI 10.1007/s00125-004-1569-2
-
C Cruciani-Guglielmacci A Hervalet L Douared NM Sanders BE Levin A Ktorza C Magnan 2004 Beta oxidation in the brain is required for the effects of non-esterified fatty acids on glucose-induced insulin secretion in rats Diabetologia 47 2032 2038 15599702 10.1007/s00125-004-1569-2 1:CAS:528:DC%2BD2cXhtVOqs7jF (Pubitemid 40110215)
-
(2004)
Diabetologia
, vol.47
, Issue.11
, pp. 2032-2038
-
-
Cruciani-Guglielmacci, C.1
Hervalet, A.2
Douared, L.3
Sanders, N.M.4
Levin, B.E.5
Ktorza, A.6
Magnan, C.7
-
144
-
-
33646012618
-
Effects of oleic acid on distinct populations of neurons in the hypothalamic arcuate nucleus are dependent on extracellular glucose levels
-
16306178 10.1152/jn.00697.2005 1:STN:280:DC%2BD287gs1Cgtg%3D%3D
-
R Wang C Cruciani-Guglielmacci S Migrenne C Magnan VE Cotero VH Routh 2006 Effects of oleic acid on distinct populations of neurons in the hypothalamic arcuate nucleus are dependent on extracellular glucose levels J Neurophysiol 95 1491 1498 16306178 10.1152/jn.00697.2005 1:STN:280: DC%2BD287gs1Cgtg%3D%3D
-
(2006)
J Neurophysiol
, vol.95
, pp. 1491-1498
-
-
Wang, R.1
Cruciani-Guglielmacci, C.2
Migrenne, S.3
Magnan, C.4
Cotero, V.E.5
Routh, V.H.6
-
145
-
-
0028330348
-
Characterization of the influence of unsaturated free fatty acids on brain GABA/benzodiazepine receptor binding in vitro
-
8133272 10.1046/j.1471-4159.1994.62041432.x 1:CAS:528:DyaK2cXitV2hur8%3D
-
MR Witt M Nielsen 1994 Characterization of the influence of unsaturated free fatty acids on brain GABA/benzodiazepine receptor binding in vitro J Neurochem 62 1432 1439 8133272 10.1046/j.1471-4159.1994.62041432.x 1:CAS:528:DyaK2cXitV2hur8%3D
-
(1994)
J Neurochem
, vol.62
, pp. 1432-1439
-
-
Witt, M.R.1
Nielsen, M.2
-
146
-
-
0033859292
-
PKA and arachidonic acid activation of human recombinant ClC-2 chloride channels
-
10898715 1:CAS:528:DC%2BD3cXltlyqtb8%3D
-
KP Tewari DH Malinowska AM Sherry J Cuppoletti 2000 PKA and arachidonic acid activation of human recombinant ClC-2 chloride channels Am J Physiol Cell Physiol 279 C40 C50 10898715 1:CAS:528:DC%2BD3cXltlyqtb8%3D
-
(2000)
Am J Physiol Cell Physiol
, vol.279
-
-
Tewari, K.P.1
Malinowska, D.H.2
Sherry, A.M.3
Cuppoletti, J.4
-
147
-
-
13544277616
-
Effects of unsaturated fatty acids on calcium-activated potassium current in gastric myocytes of guinea pigs
-
15655819 1:CAS:528:DC%2BD2MXisVKjsLk%3D
-
HF Zheng XL Li ZY Jin JB Sun ZL Li WX Xu 2005 Effects of unsaturated fatty acids on calcium-activated potassium current in gastric myocytes of guinea pigs World J Gastroenterol 11 672 675 15655819 1:CAS:528:DC%2BD2MXisVKjsLk%3D
-
(2005)
World J Gastroenterol
, vol.11
, pp. 672-675
-
-
Zheng, H.F.1
Li, X.L.2
Jin, Z.Y.3
Sun, J.B.4
Li, Z.L.5
Xu, W.X.6
-
148
-
-
0347995062
-
Suppression of Calcium Sparks in Rat Ventricular Myocytes and Direct Inhibition of Sheep Cardiac RyR Channels by EPA, DHA and Oleic Acid
-
DOI 10.1007/s00232-003-0628-9
-
BN Honen DA Saint DR Laver 2003 Suppression of calcium sparks in rat ventricular myocytes and direct inhibition of sheep cardiac RyR channels by EPA, DHA and oleic acid J Membr Biol 196 95 103 14724746 10.1007/s00232-003-0628-9 1:CAS:528:DC%2BD2cXjsl2ruw%3D%3D (Pubitemid 38010692)
-
(2003)
Journal of Membrane Biology
, vol.196
, Issue.2
, pp. 95-103
-
-
Honen, B.N.1
Saint, D.A.2
Laver, D.R.3
-
149
-
-
0025169805
-
Inhibition of Na, K-ATPase and sodium pump by protein kinase C regulators sphingosine, lysophosphatidylcholine, and oleic acid
-
2152929 1:CAS:528:DyaK3cXjt1Ggtw%3D%3D
-
K Oishi B Zheng JF Kuo 1990 Inhibition of Na, K-ATPase and sodium pump by protein kinase C regulators sphingosine, lysophosphatidylcholine, and oleic acid J Biol Chem 265 70 75 2152929 1:CAS:528:DyaK3cXjt1Ggtw%3D%3D
-
(1990)
J Biol Chem
, vol.265
, pp. 70-75
-
-
Oishi, K.1
Zheng, B.2
Kuo, J.F.3
-
150
-
-
16244388931
-
Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis
-
DOI 10.1038/nm1201
-
TK Lam A Pocai R Gutierrez-Juarez S Obici J Bryan L Aguilar-Bryan GJ Schwartz L Rossetti 2005 Hypothalamic sensing of circulating fatty acids is required for glucose homeostasis Nat Med 11 320 327 15735652 10.1038/nm1201 1:CAS:528:DC%2BD2MXhvVSqsro%3D (Pubitemid 40460561)
-
(2005)
Nature Medicine
, vol.11
, Issue.3
, pp. 320-327
-
-
Lam, T.K.T.1
Pocai, A.2
Gutierrez-Juarez, R.3
Obici, S.4
Bryan, J.5
Aguilar-Bryan, L.6
Schwartz, G.J.7
Rossetti, L.8
-
151
-
-
34249804134
-
Fatty acid sensing and nervous control of energy homeostasis
-
DOI 10.1016/j.diabet.2007.01.006, PII S1262363607000638
-
S Migrenne C Magnan C Cruciani-Guglielmacci 2007 Fatty acid sensing and nervous control of energy homeostasis Diabetes Metab 33 177 182 17475532 10.1016/j.diabet.2007.01.006 1:CAS:528:DC%2BD2sXptFGnur8%3D (Pubitemid 46856252)
-
(2007)
Diabetes and Metabolism
, vol.33
, Issue.3
, pp. 177-182
-
-
Migrenne, S.1
Magnan, C.2
Cruciani-Guglielmacci, C.3
-
152
-
-
0021473173
-
Suppression of food intake by intravenous nutrients and insulin in the baboon
-
6380317 1:CAS:528:DyaL2cXlsFSntrc%3D
-
SC Woods LJ Stein LD McKay D Porte Jr 1984 Suppression of food intake by intravenous nutrients and insulin in the baboon Am J Physiol 247 R393 R401 6380317 1:CAS:528:DyaL2cXlsFSntrc%3D
-
(1984)
Am J Physiol
, vol.247
-
-
Woods, S.C.1
Stein, L.J.2
McKay, L.D.3
Porte Jr., D.4
-
153
-
-
0031414267
-
Pathways of Fos expression in locus ceruleus, dorsal vagal complex, and PVN in response to intestinal lipid
-
9435662 1:CAS:528:DyaK1cXjsVOqsw%3D%3D
-
H Monnikes G Lauer C Bauer J Tebbe TT Zittel R Arnold 1997 Pathways of Fos expression in locus ceruleus, dorsal vagal complex, and PVN in response to intestinal lipid Am J Physiol 273 R2059 R2071 9435662 1:CAS:528: DyaK1cXjsVOqsw%3D%3D
-
(1997)
Am J Physiol
, vol.273
-
-
Monnikes, H.1
Lauer, G.2
Bauer, C.3
Tebbe, J.4
Zittel, T.T.5
Arnold, R.6
-
154
-
-
0034063725
-
The role of long-chain fatty acids in regulating food intake and cholecystokinin release in humans
-
10764713 10.1136/gut.46.5.689 1:CAS:528:DC%2BD3cXjsVSgsrw%3D
-
D Matzinger L Degen J Drewe J Meuli R Duebendorfer N Ruckstuhl M D'Amato L Rovati C Beglinger 2000 The role of long-chain fatty acids in regulating food intake and cholecystokinin release in humans Gut 46 688 693 10764713 10.1136/gut.46.5.689 1:CAS:528:DC%2BD3cXjsVSgsrw%3D
-
(2000)
Gut
, vol.46
, pp. 688-693
-
-
Matzinger, D.1
Degen, L.2
Drewe, J.3
Meuli, J.4
Duebendorfer, R.5
Ruckstuhl, N.6
D'Amato, M.7
Rovati, L.8
Beglinger, C.9
-
155
-
-
0033067578
-
Gut vagal afferent lesions increase meal size but do not block gastric preload-induced feeding suppression
-
10362740 1:CAS:528:DyaK1MXksVWmsLc%3D
-
GJ Schwartz CF Salorio C Skoglund TH Moran 1999 Gut vagal afferent lesions increase meal size but do not block gastric preload-induced feeding suppression Am J Physiol 276 R1623 R1629 10362740 1:CAS:528:DyaK1MXksVWmsLc%3D
-
(1999)
Am J Physiol
, vol.276
-
-
Schwartz, G.J.1
Salorio, C.F.2
Skoglund, C.3
Moran, T.H.4
-
156
-
-
0036065628
-
Central administration of oleic acid inhibits glucose production and food intake
-
11812732 10.2337/diabetes.51.2.271 1:CAS:528:DC%2BD38XhtVaqtbg%3D
-
S Obici Z Feng K Morgan D Stein G Karkanias L Rossetti 2002 Central administration of oleic acid inhibits glucose production and food intake Diabetes 51 271 275 11812732 10.2337/diabetes.51.2.271 1:CAS:528: DC%2BD38XhtVaqtbg%3D
-
(2002)
Diabetes
, vol.51
, pp. 271-275
-
-
Obici, S.1
Feng, Z.2
Morgan, K.3
Stein, D.4
Karkanias, G.5
Rossetti, L.6
-
157
-
-
3843114555
-
Hypothalamic responses to long-chain fatty acids are nutritionally regulated
-
DOI 10.1074/jbc.M400458200
-
K Morgan S Obici L Rossetti 2004 Hypothalamic responses to long-chain fatty acids are nutritionally regulated J Biol Chem 279 31139 31148 15155754 10.1074/jbc.M400458200 1:CAS:528:DC%2BD2cXlslOkurY%3D (Pubitemid 39037776)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.30
, pp. 31139-31148
-
-
Morgan, K.1
Obici, S.2
Rossetti, L.3
-
158
-
-
0038037734
-
Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production
-
DOI 10.1038/nm873
-
S Obici Z Feng A Arduini R Conti L Rossetti 2003 Inhibition of hypothalamic carnitine palmitoyltransferase-1 decreases food intake and glucose production Nat Med 9 756 761 12754501 10.1038/nm873 1:CAS:528: DC%2BD3sXktFOnu74%3D (Pubitemid 36749226)
-
(2003)
Nature Medicine
, vol.9
, Issue.6
, pp. 756-761
-
-
Obici, S.1
Feng, Z.2
Arduini, A.3
Conti, R.4
Rossetti, L.5
-
159
-
-
31544465941
-
Molecular disruption of hypothalamic nutrient sensing induces obesity
-
DOI 10.1038/nn1626, PII NN1626
-
W He TK Lam S Obici L Rossetti 2006 Molecular disruption of hypothalamic nutrient sensing induces obesity Nat Neurosci 9 227 233 16415870 10.1038/nn1626 1:CAS:528:DC%2BD28XotVegug%3D%3D (Pubitemid 43164546)
-
(2006)
Nature Neuroscience
, vol.9
, Issue.2
, pp. 227-233
-
-
He, W.1
Lam, T.K.T.2
Obici, S.3
Rossetti, L.4
-
160
-
-
17844379953
-
Hypothalamic sensing of fatty acids
-
DOI 10.1038/nn1456
-
TK Lam GJ Schwartz L Rossetti 2005 Hypothalamic sensing of fatty acids Nat Neurosci 8 579 584 15856066 10.1038/nn1456 1:CAS:528:DC%2BD2MXjsFyktbs%3D (Pubitemid 40594197)
-
(2005)
Nature Neuroscience
, vol.8
, Issue.5
, pp. 579-584
-
-
Lam, T.K.T.1
Schwartz, G.J.2
Rossetti, L.3
-
161
-
-
0026080124
-
Influence of fatty acid oxidation in lateral hypothalamus on food intake and body composition
-
1877693 1:CAS:528:DyaK3MXlvVSgsLk%3D
-
JL Beverly RJ Martin 1991 Influence of fatty acid oxidation in lateral hypothalamus on food intake and body composition Am J Physiol 261 R339 R343 1877693 1:CAS:528:DyaK3MXlvVSgsLk%3D
-
(1991)
Am J Physiol
, vol.261
-
-
Beverly, J.L.1
Martin, R.J.2
-
162
-
-
0038646086
-
Localization of messenger RNAs encoding enzymes associated with malonyl-CoA metabolism in mouse brain
-
12638127 10.1016/S1567-133X(02)00013-3 1:CAS:528:DC%2BD38XpsFGitbo%3D
-
A Sorensen MT Travers RG Vernon NT Price MC Barber 2002 Localization of messenger RNAs encoding enzymes associated with malonyl-CoA metabolism in mouse brain Brain Res Gene Expr Patterns 1 167 173 12638127 10.1016/S1567-133X(02) 00013-3 1:CAS:528:DC%2BD38XpsFGitbo%3D
-
(2002)
Brain Res Gene Expr Patterns
, vol.1
, pp. 167-173
-
-
Sorensen, A.1
Travers, M.T.2
Vernon, R.G.3
Price, N.T.4
Barber, M.C.5
-
163
-
-
0036841351
-
Expression of FAS within hypothalamic neurons: A model for decreased food intake after C75 treatment
-
12376313 1:CAS:528:DC%2BD38XovVOls7w%3D
-
EK Kim I Miller LE Landree FF Borisy-Rudin P Brown T Tihan CA Townsend LA Witters TH Moran FP Kuhajda GV Ronnett 2002 Expression of FAS within hypothalamic neurons: a model for decreased food intake after C75 treatment Am J Physiol Endocrinol Metab 283 E867 E879 12376313 1:CAS:528:DC%2BD38XovVOls7w%3D
-
(2002)
Am J Physiol Endocrinol Metab
, vol.283
-
-
Kim, E.K.1
Miller, I.2
Landree, L.E.3
Borisy-Rudin, F.F.4
Brown, P.5
Tihan, T.6
Townsend, C.A.7
Witters, L.A.8
Moran, T.H.9
Kuhajda, F.P.10
Ronnett, G.V.11
-
164
-
-
0034733730
-
Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors
-
DOI 10.1126/science.288.5475.2379
-
TM Loftus DE Jaworsky GL Frehywot CA Townsend GV Ronnett MD Lane FP Kuhajda 2000 Reduced food intake and body weight in mice treated with fatty acid synthase inhibitors Science 288 2379 2381 10875926 10.1126/science.288.5475. 2379 1:CAS:528:DC%2BD3cXkslWitb0%3D (Pubitemid 30448165)
-
(2000)
Science
, vol.288
, Issue.5475
, pp. 2379-2381
-
-
Loftus, T.M.1
Jaworsky, D.E.2
Frehywot, C.L.3
Townsend, C.A.4
Ronnett, G.V.5
Daniel Lane, M.6
Kuhajda, F.P.7
-
167
-
-
28844433549
-
A role for hypothalamic malonyl-CoA in the control of food intake
-
DOI 10.1074/jbc.C500398200
-
Z Hu Y Dai M Prentki S Chohnan MD Lane 2005 A role for hypothalamic malonyl-CoA in the control of food intake J Biol Chem 280 39681 39683 16219771 10.1074/jbc.C500398200 1:CAS:528:DC%2BD2MXht1GjsrbO (Pubitemid 41779099)
-
(2005)
Journal of Biological Chemistry
, vol.280
, Issue.48
, pp. 39681-39683
-
-
Hu, Z.1
Dai, Y.2
Prentki, M.3
Chohnan, S.4
Lane, M.D.5
-
168
-
-
19744377649
-
Fatty acid metabolism as a target for obesity treatment
-
DOI 10.1016/j.physbeh.2005.04.014, PII S0031938405001150, Proceedings from the 2004 Meeting of the Society for the Study of Ingestive Behaviour
-
GV Ronnett EK Kim LE Landree Y Tu 2005 Fatty acid metabolism as a target for obesity treatment Physiol Behav 85 25 35 15878185 10.1016/j.physbeh.2005.04. 014 1:CAS:528:DC%2BD2MXks1ahsrg%3D (Pubitemid 40744974)
-
(2005)
Physiology and Behavior
, vol.85
, Issue.1
, pp. 25-35
-
-
Ronnett, G.V.1
Kim, E.-K.2
Landree, L.E.3
Tu, Y.4
-
169
-
-
2442631468
-
C75, a Fatty Acid Synthase Inhibitor, Reduces Food Intake via Hypothalamic AMP-activated Protein Kinase
-
DOI 10.1074/jbc.M402165200
-
EK Kim I Miller S Aja LE Landree M Pinn J McFadden FP Kuhajda TH Moran GV Ronnett 2004 C75, a fatty acid synthase inhibitor, reduces food intake via hypothalamic AMP-activated protein kinase J Biol Chem 279 19970 19976 15028725 10.1074/jbc.M402165200 1:CAS:528:DC%2BD2cXjs1Whsrg%3D (Pubitemid 38623439)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.19
, pp. 19970-19976
-
-
Kim, E.-K.1
Miller, I.2
Aja, S.3
Landree, L.E.4
Pinn, M.5
McFadden, J.6
Kuhajda, F.P.7
Moran, T.H.8
Ronnett, G.V.9
-
170
-
-
0037610811
-
Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem
-
DOI 10.1073/pnas.1031698100
-
S Gao MD Lane 2003 Effect of the anorectic fatty acid synthase inhibitor C75 on neuronal activity in the hypothalamus and brainstem Proc Natl Acad Sci USA 100 5628 5633 12724522 10.1073/pnas.1031698100 1:CAS:528: DC%2BD3sXjvFOmu7w%3D (Pubitemid 36576859)
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, Issue.10
, pp. 5628-5633
-
-
Gao, S.1
Lane, M.D.2
-
171
-
-
0024995157
-
A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation
-
1698143 10.1210/endo-127-4-1580 1:CAS:528:DyaK3cXlvVGisrs%3D
-
Y Sako VE Grill 1990 A 48-hour lipid infusion in the rat time-dependently inhibits glucose-induced insulin secretion and B cell oxidation through a process likely coupled to fatty acid oxidation Endocrinology 127 1580 1589 1698143 10.1210/endo-127-4-1580 1:CAS:528:DyaK3cXlvVGisrs%3D
-
(1990)
Endocrinology
, vol.127
, pp. 1580-1589
-
-
Sako, Y.1
Grill, V.E.2
-
172
-
-
0028268936
-
Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle
-
8113418 10.1172/JCI117042 1:CAS:528:DyaK2cXktVWntb4%3D
-
YP Zhou VE Grill 1994 Long-term exposure of rat pancreatic islets to fatty acids inhibits glucose-induced insulin secretion and biosynthesis through a glucose fatty acid cycle J Clin Invest 93 870 876 8113418 10.1172/JCI117042 1:CAS:528:DyaK2cXktVWntb4%3D
-
(1994)
J Clin Invest
, vol.93
, pp. 870-876
-
-
Zhou, Y.P.1
Grill, V.E.2
-
173
-
-
33745863033
-
Islet β cell failure in type 2 diabetes
-
DOI 10.1172/JCI29103
-
M Prentki CJ Nolan 2006 Islet beta cell failure in type 2 diabetes J Clin Invest 116 1802 1812 16823478 10.1172/JCI29103 1:CAS:528:DC%2BD28XmvV2ltLs%3D (Pubitemid 44033300)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1802-1812
-
-
Prentki, M.1
Nolan, C.J.2
-
174
-
-
0030731946
-
Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels
-
DOI 10.1074/jbc.272.48.30261
-
S Gremlich C Bonny G Waeber B Thorens 1997 Fatty acids decrease IDX-1 expression in rat pancreatic islets and reduce GLUT2, glucokinase, insulin, and somatostatin levels J Biol Chem 272 30261 30269 9374511 10.1074/jbc.272.48.30261 1:CAS:528:DyaK2sXnslGhurk%3D (Pubitemid 27512230)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.48
, pp. 30261-30269
-
-
Gremlich, S.1
Bonny, C.2
Waeber, G.3
Thorens, B.4
-
175
-
-
39149104320
-
The role for endoplasmic reticulum stress in diabetes mellitus
-
DOI 10.1210/er.2007-0015
-
DL Eizirik AK Cardozo M Cnop 2008 The role for endoplasmic reticulum stress in diabetes mellitus Endocr Rev 29 42 61 18048764 10.1210/er.2007-0015 1:CAS:528:DC%2BD1cXivFGqs7s%3D (Pubitemid 351252746)
-
(2008)
Endocrine Reviews
, vol.29
, Issue.1
, pp. 42-61
-
-
Eizirik, D.L.1
Cardozo, A.K.2
Cnop, M.3
-
176
-
-
0038025293
-
C75 inhibits food intake by increasing CNS glucose metabolism [2]
-
DOI 10.1038/nm0503-483
-
MD Wortman DJ Clegg D D'Alessio SC Woods RJ Seeley 2003 C75 inhibits food intake by increasing CNS glucose metabolism Nat Med 9 483 485 12724740 10.1038/nm0503-483 1:CAS:528:DC%2BD3sXjtlamsbs%3D (Pubitemid 36597076)
-
(2003)
Nature Medicine
, vol.9
, Issue.5
, pp. 483-485
-
-
Wortman, M.D.1
Clegg, D.J.2
D'Alessio, D.3
Woods, S.C.4
Seeley, R.J.5
-
177
-
-
70449637789
-
Effects of maternal genotype and diet on offspring glucose and fatty acid-sensing ventromedial hypothalamic nucleus neurons
-
19710389 1:CAS:528:DC%2BD1MXhsValsbfP
-
C Le Foll BG Irani C Magnan A Dunn-Meynell BE Levin 2009 Effects of maternal genotype and diet on offspring glucose and fatty acid-sensing ventromedial hypothalamic nucleus neurons Am J Physiol Regul Integr Comp Physiol 297 R1351 R1357 19710389 1:CAS:528:DC%2BD1MXhsValsbfP
-
(2009)
Am J Physiol Regul Integr Comp Physiol
, vol.297
-
-
Le Foll, C.1
Irani, B.G.2
Magnan, C.3
Dunn-Meynell, A.4
Levin, B.E.5
-
178
-
-
33747039288
-
Mitochondrial reactive oxygen species are required for hypothalamic glucose sensing
-
DOI 10.2337/db06-0086
-
C Leloup C Magnan A Benani E Bonnet T Alquier G Offer A Carriere A Periquet Y Fernandez A Ktorza L Casteilla L Penicaud 2006 Mitochondrial reactive oxygen species are required for hypothalamic glucose sensing Diabetes 55 2084 2090 16804079 10.2337/db06-0086 1:CAS:528:DC%2BD28XmvVChtLk%3D (Pubitemid 44509983)
-
(2006)
Diabetes
, vol.55
, Issue.7
, pp. 2084-2090
-
-
Leloup, C.1
Magnan, C.2
Benani, A.3
Bonnet, E.4
Alquier, T.5
Offer, G.6
Carriere, A.7
Periquet, A.8
Fernandez, Y.9
Ktorza, A.10
Casteilla, L.11
Penicaud, L.12
-
179
-
-
33847065926
-
Role for mitochondrial reactive oxygen species in brain lipid sensing: Redox regulation of food intake
-
17192477 10.2337/db06-0440 1:CAS:528:DC%2BD2sXhtVWlt70%3D
-
A Benani S Troy MC Carmona X Fioramonti A Lorsignol C Leloup L Casteilla L Penicaud 2007 Role for mitochondrial reactive oxygen species in brain lipid sensing: redox regulation of food intake Diabetes 56 152 160 17192477 10.2337/db06-0440 1:CAS:528:DC%2BD2sXhtVWlt70%3D
-
(2007)
Diabetes
, vol.56
, pp. 152-160
-
-
Benani, A.1
Troy, S.2
Carmona, M.C.3
Fioramonti, X.4
Lorsignol, A.5
Leloup, C.6
Casteilla, L.7
Penicaud, L.8
-
180
-
-
49649122302
-
UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals
-
18668043 10.1038/nature07181 1:CAS:528:DC%2BD1cXpvVaisr0%3D
-
ZB Andrews ZW Liu N Walllingford DM Erion E Borok JM Friedman MH Tschop M Shanabrough G Cline GI Shulman A Coppola XB Gao TL Horvath S Diano 2008 UCP2 mediates ghrelin's action on NPY/AgRP neurons by lowering free radicals Nature 454 846 851 18668043 10.1038/nature07181 1:CAS:528:DC%2BD1cXpvVaisr0%3D
-
(2008)
Nature
, vol.454
, pp. 846-851
-
-
Andrews, Z.B.1
Liu, Z.W.2
Walllingford, N.3
Erion, D.M.4
Borok, E.5
Friedman, J.M.6
Tschop, M.H.7
Shanabrough, M.8
Cline, G.9
Shulman, G.I.10
Coppola, A.11
Gao, X.B.12
Horvath, T.L.13
Diano, S.14
-
181
-
-
0030830935
-
Peroxide modulation of slow onset potentiation in rat hippocampus
-
9348338 1:CAS:528:DyaK2sXnsFalsbo%3D
-
JM Auerbach M Segal 1997 Peroxide modulation of slow onset potentiation in rat hippocampus J Neurosci 17 8695 8701 9348338 1:CAS:528:DyaK2sXnsFalsbo%3D
-
(1997)
J Neurosci
, vol.17
, pp. 8695-8701
-
-
Auerbach, J.M.1
Segal, M.2
-
182
-
-
33846262003
-
2 signaling in the nigrostriatal dopamine pathway via ATP-sensitive potassium channels: Issues and answers
-
DOI 10.1089/ars.2007.9.219
-
MV Avshalumov L Bao JC Patel ME Rice 2007 H2O2 signaling in the nigrostriatal dopamine pathway via ATP-sensitive potassium channels: issues and answers Antioxid Redox Signal 9 219 231 17115944 10.1089/ars.2007.9.219 1:CAS:528:DC%2BD28Xht1yis7bI (Pubitemid 46105421)
-
(2007)
Antioxidants and Redox Signaling
, vol.9
, Issue.2
, pp. 219-231
-
-
Avshalumov, M.V.1
Bao, L.2
Patel, J.C.3
Rice, M.E.4
-
183
-
-
63749097442
-
Fuel utilization by hypothalamic neurons: Roles for ROS
-
19084428 10.1016/j.tem.2008.10.003 1:CAS:528:DC%2BD1MXisFGltrs%3D
-
TL Horvath ZB Andrews S Diano 2009 Fuel utilization by hypothalamic neurons: roles for ROS Trends Endocrinol Metab 20 78 87 19084428 10.1016/j.tem.2008.10.003 1:CAS:528:DC%2BD1MXisFGltrs%3D
-
(2009)
Trends Endocrinol Metab
, vol.20
, pp. 78-87
-
-
Horvath, T.L.1
Andrews, Z.B.2
Diano, S.3
-
184
-
-
70649092451
-
Hormone and glucose signalling in POMC and AgRP neurons
-
19770186 10.1113/jphysiol.2009.179192 1:CAS:528:DC%2BD1MXhsVyrtb7L
-
BF Belgardt T Okamura JC Bruning 2009 Hormone and glucose signalling in POMC and AgRP neurons J Physiol 587 5305 5314 19770186 10.1113/jphysiol.2009. 179192 1:CAS:528:DC%2BD1MXhsVyrtb7L
-
(2009)
J Physiol
, vol.587
, pp. 5305-5314
-
-
Belgardt, B.F.1
Okamura, T.2
Bruning, J.C.3
-
185
-
-
0018621289
-
Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons
-
116135 10.1038/282503a0 1:CAS:528:DyaL3cXht1agtrc%3D
-
SC Woods EC Lotter LD McKay D Porte Jr 1979 Chronic intracerebroventricular infusion of insulin reduces food intake and body weight of baboons Nature 282 503 505 116135 10.1038/282503a0 1:CAS:528: DyaL3cXht1agtrc%3D
-
(1979)
Nature
, vol.282
, pp. 503-505
-
-
Woods, S.C.1
Lotter, E.C.2
McKay, L.D.3
Porte Jr., D.4
-
186
-
-
0027524524
-
Chronic intrahypothalamic insulin infusion in the rat: Behavioral specificity
-
DOI 10.1016/0031-9384(93)90320-F
-
MK McGowan KM Andrews D Fenner SP Grossman 1993 Chronic intrahypothalamic insulin infusion in the rat: behavioral specificity Physiol Behav 54 1031 1034 8248369 10.1016/0031-9384(93)90320-F 1:CAS:528:DyaK3sXms1aqu7g%3D (Pubitemid 23303885)
-
(1993)
Physiology and Behavior
, vol.54
, Issue.5
, pp. 1031-1034
-
-
McGowan, M.K.1
Andrews, K.M.2
Fenner, D.3
Grossman, S.P.4
-
187
-
-
0019498710
-
Regulation of food intake and body weight in insulin
-
7014326 10.1007/BF00254493 1:CAS:528:DyaL3MXktFymtbk%3D
-
D Porte Jr SC Woods 1981 Regulation of food intake and body weight in insulin Diabetologia 20 Suppl 274 280 7014326 10.1007/BF00254493 1:CAS:528:DyaL3MXktFymtbk%3D
-
(1981)
Diabetologia
, vol.20
, Issue.SUPPL
, pp. 274-280
-
-
Porte Jr., D.1
Woods, S.C.2
-
188
-
-
0034703229
-
Role of brain insulin receptor in control of body weight and reproduction
-
11000114 10.1126/science.289.5487.2122 1:CAS:528:DC%2BD3cXmvVClsLY%3D
-
JC Bruning D Gautam DJ Burks J Gillette M Schubert PC Orban R Klein W Krone D Muller-Wieland CR Kahn 2000 Role of brain insulin receptor in control of body weight and reproduction Science 289 2122 2125 11000114 10.1126/science.289.5487.2122 1:CAS:528:DC%2BD3cXmvVClsLY%3D
-
(2000)
Science
, vol.289
, pp. 2122-2125
-
-
Bruning, J.C.1
Gautam, D.2
Burks, D.J.3
Gillette, J.4
Schubert, M.5
Orban, P.C.6
Klein, R.7
Krone, W.8
Muller-Wieland, D.9
Kahn, C.R.10
-
189
-
-
0034611732
-
Central nervous system control of food intake
-
10766253 1:CAS:528:DC%2BD3cXis1Grur4%3D
-
MW Schwartz SC Woods D Porte Jr RJ Seeley DG Baskin 2000 Central nervous system control of food intake Nature 404 661 671 10766253 1:CAS:528: DC%2BD3cXis1Grur4%3D
-
(2000)
Nature
, vol.404
, pp. 661-671
-
-
Schwartz, M.W.1
Woods, S.C.2
Porte Jr., D.3
Seeley, R.J.4
Baskin, D.G.5
-
190
-
-
12344277552
-
Diabetes, obesity, and the brain
-
DOI 10.1126/science.1104344
-
MW Schwartz D Porte Jr 2005 Diabetes, obesity, and the brain Science 307 375 379 15662002 10.1126/science.1104344 1:CAS:528:DC%2BD2MXksFyhsQ%3D%3D (Pubitemid 40139972)
-
(2005)
Science
, vol.307
, Issue.5708
, pp. 375-379
-
-
Schwartz, M.W.1
Porte Jr., D.2
-
191
-
-
45749158925
-
Central insulin action regulates peripheral glucose and fat metabolism in mice
-
18451994 1:CAS:528:DC%2BD1cXntVCmtbw%3D
-
L Koch FT Wunderlich J Seibler AC Konner B Hampel S Irlenbusch G Brabant CR Kahn F Schwenk JC Bruning 2008 Central insulin action regulates peripheral glucose and fat metabolism in mice J Clin Invest 118 2132 2147 18451994 1:CAS:528:DC%2BD1cXntVCmtbw%3D
-
(2008)
J Clin Invest
, vol.118
, pp. 2132-2147
-
-
Koch, L.1
Wunderlich, F.T.2
Seibler, J.3
Konner, A.C.4
Hampel, B.5
Irlenbusch, S.6
Brabant, G.7
Kahn, C.R.8
Schwenk, F.9
Bruning, J.C.10
-
192
-
-
34249651956
-
Insulin Action in AgRP-Expressing Neurons Is Required for Suppression of Hepatic Glucose Production
-
DOI 10.1016/j.cmet.2007.05.004, PII S1550413107001313
-
AC Konner R Janoschek L Plum SD Jordan E Rother X Ma C Xu P Enriori B Hampel GS Barsh CR Kahn MA Cowley FM Ashcroft JC Bruning 2007 Insulin action in AgRP-expressing neurons is required for suppression of hepatic glucose production Cell Metab 5 438 449 17550779 10.1016/j.cmet.2007.05.004 1:CAS:528:DC%2BD2sXmslOqsrc%3D (Pubitemid 46825497)
-
(2007)
Cell Metabolism
, vol.5
, Issue.6
, pp. 438-449
-
-
Konner, A.C.1
Janoschek, R.2
Plum, L.3
Jordan, S.D.4
Rother, E.5
Ma, X.6
Xu, C.7
Enriori, P.8
Hampel, B.9
Barsh, G.S.10
Kahn, C.R.11
Cowley, M.A.12
Ashcroft, F.M.13
Bruning, J.C.14
-
193
-
-
0036913187
-
Hypothalamic insulin signaling is required for inhibition of glucose production
-
DOI 10.1038/nm798
-
S Obici BB Zhang G Karkanias L Rossetti 2002 Hypothalamic insulin signaling is required for inhibition of glucose production Nat Med 8 1376 1382 12426561 10.1038/nm798 1:CAS:528:DC%2BD38XptVSgsbY%3D (Pubitemid 36019422)
-
(2002)
Nature Medicine
, vol.8
, Issue.12
, pp. 1376-1382
-
-
Obici, S.1
Zhang, B.B.2
Karkanias, G.3
Rossetti, L.4
-
194
-
-
0037315042
-
Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: A key mediator of insulin-induced anorexia
-
DOI 10.2337/diabetes.52.2.227
-
KD Niswender CD Morrison DJ Clegg R Olson DG Baskin MG Myers Jr RJ Seeley MW Schwartz 2003 Insulin activation of phosphatidylinositol 3-kinase in the hypothalamic arcuate nucleus: a key mediator of insulin-induced anorexia Diabetes 52 227 231 12540590 10.2337/diabetes.52.2.227 1:CAS:528: DC%2BD3sXhtFagu78%3D (Pubitemid 36173172)
-
(2003)
Diabetes
, vol.52
, Issue.2
, pp. 227-231
-
-
Niswender, K.D.1
Morrison, C.D.2
Clegg, D.J.3
Olson, R.4
Baskin, D.G.5
Myers Jr., M.G.6
Seeley, R.J.7
Schwartz, M.W.8
-
195
-
-
66149083518
-
Insulin blunts the response of glucose-excited neurons in the ventrolateral-ventromedial hypothalamic nucleus to decreased glucose
-
19223652 10.1152/ajpendo.90932.2008 1:CAS:528:DC%2BD1MXlvFagsL0%3D
-
VE Cotero VH Routh 2009 Insulin blunts the response of glucose-excited neurons in the ventrolateral-ventromedial hypothalamic nucleus to decreased glucose Am J Physiol Endocrinol Metab 296 E1101 E1109 19223652 10.1152/ajpendo.90932.2008 1:CAS:528:DC%2BD1MXlvFagsL0%3D
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
-
-
Cotero, V.E.1
Routh, V.H.2
-
196
-
-
0028845877
-
Leptin levels in human and rodent: Measurement of plasma leptin and ob RNA in obese and weight-reduced subjects
-
7584987 10.1038/nm1195-1155 1:CAS:528:DyaK2MXptFahs7s%3D
-
M Maffei J Halaas E Ravussin RE Pratley GH Lee Y Zhang H Fei S Kim R Lallone S Ranganathan PA Kern JM Friedman 1995 Leptin levels in human and rodent: measurement of plasma leptin and ob RNA in obese and weight-reduced subjects Nat Med 1 1155 1161 7584987 10.1038/nm1195-1155 1:CAS:528: DyaK2MXptFahs7s%3D
-
(1995)
Nat Med
, vol.1
, pp. 1155-1161
-
-
Maffei, M.1
Halaas, J.2
Ravussin, E.3
Pratley, R.E.4
Lee, G.H.5
Zhang, Y.6
Fei, H.7
Kim, S.8
Lallone, R.9
Ranganathan, S.10
Kern, P.A.11
Friedman, J.M.12
-
197
-
-
0028793697
-
Leptin levels reflect body lipid content in mice: Evidence for diet-induced resistance to leptin action
-
7489415 10.1038/nm1295-1311 1:CAS:528:DyaK2MXpslGhur8%3D
-
RC Frederich A Hamann S Anderson B Lollmann BB Lowell JS Flier 1995 Leptin levels reflect body lipid content in mice: evidence for diet-induced resistance to leptin action Nat Med 1 1311 1314 7489415 10.1038/nm1295-1311 1:CAS:528:DyaK2MXpslGhur8%3D
-
(1995)
Nat Med
, vol.1
, pp. 1311-1314
-
-
Frederich, R.C.1
Hamann, A.2
Anderson, S.3
Lollmann, B.4
Lowell, B.B.5
Flier, J.S.6
-
198
-
-
0028139089
-
Positional cloning of the mouse obese gene and its human homologue
-
DOI 10.1038/372425a0
-
Y Zhang R Proenca M Maffei M Barone L Leopold JM Friedman 1994 Positional cloning of the mouse obese gene and its human homologue Nature 372 425 432 7984236 10.1038/372425a0 1:CAS:528:DyaK2MXisVGqsbs%3D (Pubitemid 24365442)
-
(1994)
Nature
, vol.372
, Issue.6505
, pp. 425-432
-
-
Zhang, Y.1
Proenca, R.2
Maffei, M.3
Barone, M.4
Leopold, L.5
Friedman, J.M.6
-
199
-
-
13344259300
-
Evidence that the diabetes gene encodes the leptin receptor: Identification of a mutation in the leptin receptor gene in db/db mice
-
DOI 10.1016/S0092-8674(00)81294-5
-
H Chen O Charlat LA Tartaglia EA Woolf X Weng SJ Ellis ND Lakey J Culpepper KJ Moore RE Breitbart GM Duyk RI Tepper JP Morgenstern 1996 Evidence that the diabetes gene encodes the leptin receptor: identification of a mutation in the leptin receptor gene in db/db mice Cell 84 491 495 8608603 10.1016/S0092-8674(00)81294-5 1:CAS:528:DyaK28XhtFWqt7s%3D (Pubitemid 26060722)
-
(1996)
Cell
, vol.84
, Issue.3
, pp. 491-495
-
-
Chen, H.1
Charlat, O.2
Tartaglia, L.A.3
Woolf, E.A.4
Weng, X.5
Ellis, S.J.6
Lakey, N.D.7
Culpepper, J.8
More, K.J.9
Breitbart, R.E.10
Duyk, G.M.11
Tepper, R.I.12
Morgenstern, J.P.13
-
200
-
-
0034776770
-
Selective deletion of leptin receptor in neurons leads to obesity
-
11602618 1:CAS:528:DC%2BD3MXns1Chs7s%3D
-
P Cohen C Zhao X Cai JM Montez SC Rohani P Feinstein P Mombaerts JM Friedman 2001 Selective deletion of leptin receptor in neurons leads to obesity J Clin Invest 108 1113 1121 11602618 1:CAS:528:DC%2BD3MXns1Chs7s%3D
-
(2001)
J Clin Invest
, vol.108
, pp. 1113-1121
-
-
Cohen, P.1
Zhao, C.2
Cai, X.3
Montez, J.M.4
Rohani, S.C.5
Feinstein, P.6
Mombaerts, P.7
Friedman, J.M.8
-
201
-
-
31044451078
-
Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes
-
DOI 10.1172/JCI24059
-
C de Luca TJ Kowalski Y Zhang JK Elmquist C Lee MW Kilimann T Ludwig SM Liu SC Chua Jr 2005 Complete rescue of obesity, diabetes, and infertility in db/db mice by neuron-specific LEPR-B transgenes J Clin Invest 115 3484 3493 16284652 10.1172/JCI24059 1:CAS:528:DC%2BD2MXhtlSqtLrE (Pubitemid 43121836)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.12
, pp. 3484-3493
-
-
De Luca, C.1
Kowalski, T.J.2
Zhang, Y.3
Elmquist, J.K.4
Lee, C.5
Kilimann, M.W.6
Ludwig, T.7
Liu, S.-M.8
Chua Jr., S.C.9
-
202
-
-
0029739970
-
Identification of targets of leptin action in rat hypothalamus
-
8787671 10.1172/JCI118891 1:CAS:528:DyaK28XlsFaksbg%3D
-
MW Schwartz RJ Seeley LA Campfield P Burn DG Baskin 1996 Identification of targets of leptin action in rat hypothalamus J Clin Invest 98 1101 1106 8787671 10.1172/JCI118891 1:CAS:528:DyaK28XlsFaksbg%3D
-
(1996)
J Clin Invest
, vol.98
, pp. 1101-1106
-
-
Schwartz, M.W.1
Seeley, R.J.2
Campfield, L.A.3
Burn, P.4
Baskin, D.G.5
-
203
-
-
33745838578
-
Central insulin action in energy and glucose homeostasis
-
DOI 10.1172/JCI29063
-
L Plum BF Belgardt JC Bruning 2006 Central insulin action in energy and glucose homeostasis J Clin Invest 116 1761 1766 16823473 10.1172/JCI29063 1:CAS:528:DC%2BD28XmvV2ltL4%3D (Pubitemid 44033295)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1761-1766
-
-
Plum, L.1
Belgardt, B.F.2
Bruning, J.C.3
-
204
-
-
43049116846
-
Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice
-
DOI 10.1172/JCI32964
-
JW Hill KW Williams C Ye J Luo N Balthasar R Coppari MA Cowley LC Cantley BB Lowell JK Elmquist 2008 Acute effects of leptin require PI3K signaling in hypothalamic proopiomelanocortin neurons in mice J Clin Invest 118 1796 1805 18382766 10.1172/JCI32964 1:CAS:528:DC%2BD1cXlsF2ntb0%3D (Pubitemid 351632382)
-
(2008)
Journal of Clinical Investigation
, vol.118
, Issue.5
, pp. 1796-1805
-
-
Hill, J.W.1
Williams, K.W.2
Ye, C.3
Luo, J.4
Balthasar, N.5
Coppari, R.6
Cowley, M.A.7
Cantley, L.C.8
Lowell, B.B.9
Elmquist, J.K.10
-
205
-
-
0035950093
-
Intracellular signalling. Key enzyme in leptin-induced anorexia
-
11677594 10.1038/35101657 1:CAS:528:DC%2BD3MXotFyksb4%3D
-
KD Niswender GJ Morton WH Stearns CJ Rhodes MG Myers Jr MW Schwartz 2001 Intracellular signalling. Key enzyme in leptin-induced anorexia Nature 413 794 795 11677594 10.1038/35101657 1:CAS:528:DC%2BD3MXotFyksb4%3D
-
(2001)
Nature
, vol.413
, pp. 794-795
-
-
Niswender, K.D.1
Morton, G.J.2
Stearns, W.H.3
Rhodes, C.J.4
Myers Jr., M.G.5
Schwartz, M.W.6
-
206
-
-
41549108590
-
PDK1 Deficiency in POMC-Expressing Cells Reveals FOXO1-Dependent and -Independent Pathways in Control of Energy Homeostasis and Stress Response
-
DOI 10.1016/j.cmet.2008.01.006, PII S1550413108000077
-
BF Belgardt A Husch E Rother MB Ernst FT Wunderlich B Hampel T Klockener D Alessi P Kloppenburg JC Bruning 2008 PDK1 deficiency in POMC-expressing cells reveals FOXO1-dependent and -independent pathways in control of energy homeostasis and stress response Cell Metab 7 291 301 18396135 10.1016/j.cmet.2008.01.006 1:CAS:528:DC%2BD1cXkvV2is70%3D (Pubitemid 351467391)
-
(2008)
Cell Metabolism
, vol.7
, Issue.4
, pp. 291-301
-
-
Belgardt, B.F.1
Husch, A.2
Rother, E.3
Ernst, M.B.4
Wunderlich, F.T.5
Hampel, B.6
Klockener, T.7
Alessi, D.8
Kloppenburg, P.9
Bruning, J.C.10
-
207
-
-
13944272576
-
The role of insulin receptor signaling in the brain
-
DOI 10.1016/j.tem.2005.01.008
-
L Plum M Schubert JC Bruning 2005 The role of insulin receptor signaling in the brain Trends Endocrinol Metab 16 59 65 15734146 10.1016/j.tem.2005.01.008 1:CAS:528:DC%2BD2MXhslegsbo%3D (Pubitemid 40270851)
-
(2005)
Trends in Endocrinology and Metabolism
, vol.16
, Issue.2
, pp. 59-65
-
-
Plum, L.1
Schubert, M.2
Bruning, J.C.3
-
208
-
-
1842484296
-
AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus
-
DOI 10.1038/nature02440
-
Y Minokoshi T Alquier N Furukawa YB Kim A Lee B Xue J Mu F Foufelle P Ferre MJ Birnbaum BJ Stuck BB Kahn 2004 AMP-kinase regulates food intake by responding to hormonal and nutrient signals in the hypothalamus Nature 428 569 574 15058305 10.1038/nature02440 1:CAS:528:DC%2BD2cXis1Gks7k%3D (Pubitemid 38480541)
-
(2004)
Nature
, vol.428
, Issue.6982
, pp. 569-574
-
-
Minokoshi, Y.1
Alquier, T.2
Furukawa, H.3
Kim, Y.-B.4
Lee, A.5
Xue, B.6
Mu, J.7
Foufelle, F.8
Ferre, P.9
Birnbaum, M.J.10
Stuck, B.J.11
Kahn, B.B.12
-
209
-
-
1842582870
-
AMP-activated Protein Kinase Plays a Role in the Control of Food Intake
-
DOI 10.1074/jbc.C300557200
-
U Andersson K Filipsson CR Abbott A Woods K Smith SR Bloom D Carling CJ Small 2004 AMP-activated protein kinase plays a role in the control of food intake J Biol Chem 279 12005 12008 14742438 10.1074/jbc.C300557200 1:CAS:528:DC%2BD2cXitl2htb8%3D (Pubitemid 38445761)
-
(2004)
Journal of Biological Chemistry
, vol.279
, Issue.13
, pp. 12005-12008
-
-
Andersson, U.1
Filipsson, K.2
Abbott, C.R.3
Woods, A.4
Smith, K.5
Bloom, S.R.6
Carling, D.7
Small, C.J.8
-
210
-
-
0037122766
-
Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase
-
DOI 10.1038/415339a
-
Y Minokoshi YB Kim OD Peroni LG Fryer C Muller D Carling BB Kahn 2002 Leptin stimulates fatty-acid oxidation by activating AMP-activated protein kinase Nature 415 339 343 11797013 10.1038/415339a 1:CAS:528: DC%2BD38Xptlamtw%3D%3D (Pubitemid 34087557)
-
(2002)
Nature
, vol.415
, Issue.6869
, pp. 339-343
-
-
Minokoshi, Y.1
Kim, Y.-B.2
Peroni, O.D.3
Fryer, L.G.D.4
Muller, C.5
Carling, D.6
Kahn, B.B.7
-
211
-
-
65649126454
-
Fasting enhances the response of arcuate neuropeptide Y-glucose-inhibited neurons to decreased extracellular glucose
-
19211911 10.1152/ajpcell.00641.2008 1:CAS:528:DC%2BD1MXkvVyhs7Y%3D
-
BA Murphy X Fioramonti N Jochnowitz K Fakira K Gagen S Contie A Lorsignol L Penicaud WJ Martin VH Routh 2009 Fasting enhances the response of arcuate neuropeptide Y-glucose-inhibited neurons to decreased extracellular glucose Am J Physiol Cell Physiol 296 C746 C756 19211911 10.1152/ajpcell.00641.2008 1:CAS:528:DC%2BD1MXkvVyhs7Y%3D
-
(2009)
Am J Physiol Cell Physiol
, vol.296
-
-
Murphy, B.A.1
Fioramonti, X.2
Jochnowitz, N.3
Fakira, K.4
Gagen, K.5
Contie, S.6
Lorsignol, A.7
Penicaud, L.8
Martin, W.J.9
Routh, V.H.10
-
212
-
-
0035433977
-
A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans
-
11473029 10.2337/diabetes.50.8.1714 1:CAS:528:DC%2BD3MXlslKnurw%3D
-
DE Cummings JQ Purnell RS Frayo K Schmidova BE Wisse DS Weigle 2001 A preprandial rise in plasma ghrelin levels suggests a role in meal initiation in humans Diabetes 50 1714 1719 11473029 10.2337/diabetes.50.8.1714 1:CAS:528:DC%2BD3MXlslKnurw%3D
-
(2001)
Diabetes
, vol.50
, pp. 1714-1719
-
-
Cummings, D.E.1
Purnell, J.Q.2
Frayo, R.S.3
Schmidova, K.4
Wisse, B.E.5
Weigle, D.S.6
-
213
-
-
0033679897
-
Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans
-
11089560 10.1210/en.141.11.4255 1:CAS:528:DC%2BD3cXnslKgs7w%3D
-
Y Date M Kojima H Hosoda A Sawaguchi MS Mondal T Suganuma S Matsukura K Kangawa M Nakazato 2000 Ghrelin, a novel growth hormone-releasing acylated peptide, is synthesized in a distinct endocrine cell type in the gastrointestinal tracts of rats and humans Endocrinology 141 4255 4261 11089560 10.1210/en.141.11.4255 1:CAS:528:DC%2BD3cXnslKgs7w%3D
-
(2000)
Endocrinology
, vol.141
, pp. 4255-4261
-
-
Date, Y.1
Kojima, M.2
Hosoda, H.3
Sawaguchi, A.4
Mondal, M.S.5
Suganuma, T.6
Matsukura, S.7
Kangawa, K.8
Nakazato, M.9
-
214
-
-
0037456519
-
The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis
-
DOI 10.1016/S0896-6273(03)00063-1
-
MA Cowley RG Smith S Diano M Tschop N Pronchuk KL Grove CJ Strasburger M Bidlingmaier M Esterman ML Heiman LM Garcia-Segura EA Nillni P Mendez MJ Low P Sotonyi JM Friedman H Liu S Pinto WF Colmers RD Cone TL Horvath 2003 The distribution and mechanism of action of ghrelin in the CNS demonstrates a novel hypothalamic circuit regulating energy homeostasis Neuron 37 649 661 12597862 10.1016/S0896-6273(03)00063-1 1:CAS:528:DC%2BD3sXhvFelt7c%3D (Pubitemid 36262986)
-
(2003)
Neuron
, vol.37
, Issue.4
, pp. 649-661
-
-
Cowley, M.A.1
Smith, R.G.2
Diano, S.3
Tschop, M.4
Pronchuk, N.5
Grove, K.L.6
Strasburger, C.J.7
Bidlingmaier, M.8
Esterman, M.9
Heiman, M.L.10
Garcia-Segura, L.M.11
Nillni, E.A.12
Mendez, P.13
Low, M.J.14
Sotonyi, P.15
Friedman, J.M.16
Liu, H.17
Pinto, S.18
Colmers, W.F.19
Cone, R.D.20
Horvath, T.L.21
more..
-
215
-
-
33745834734
-
Ghrelin action in the brain controls adipocyte metabolism
-
DOI 10.1172/JCI25811
-
C Theander-Carrillo P Wiedmer P Cettour-Rose R Nogueiras D Perez-Tilve P Pfluger TR Castaneda P Muzzin A Schurmann I Szanto MH Tschop F Rohner-Jeanrenaud 2006 Ghrelin action in the brain controls adipocyte metabolism J Clin Invest 116 1983 1993 16767221 10.1172/JCI25811 1:CAS:528:DC%2BD28XmvV2lurk%3D (Pubitemid 44033322)
-
(2006)
Journal of Clinical Investigation
, vol.116
, Issue.7
, pp. 1983-1993
-
-
Theander-Carrillo, C.1
Wiedmer, P.2
Cettour-Rose, P.3
Nogueiras, R.4
Perez-Tilve, D.5
Pfluger, P.6
Castaneda, T.R.7
Muzzin, P.8
Schurmann, A.9
Szanto, I.10
Tschop, M.H.11
Rohner-Jeanrenaud, F.12
-
216
-
-
37449021674
-
i via AMPK in hypothalamic arcuate nucleus NPY neurons
-
DOI 10.1016/j.bbrc.2007.11.166, PII S0006291X0702551X
-
D Kohno H Sone Y Minokoshi T Yada 2008 Ghrelin raises [Ca2 +]i via AMPK in hypothalamic arcuate nucleus NPY neurons Biochem Biophys Res Commun 366 388 392 18068666 10.1016/j.bbrc.2007.11.166 1:CAS:528:DC%2BD1cXhsV2lsw%3D%3D (Pubitemid 50010409)
-
(2008)
Biochemical and Biophysical Research Communications
, vol.366
, Issue.2
, pp. 388-392
-
-
Kohno, D.1
Sone, H.2
Minokoshi, Y.3
Yada, T.4
-
217
-
-
42649105456
-
Hypothalamic CaMKK2 Contributes to the Regulation of Energy Balance
-
DOI 10.1016/j.cmet.2008.02.011, PII S1550413108000703
-
KA Anderson TJ Ribar F Lin PK Noeldner MF Green MJ Muehlbauer LA Witters BE Kemp AR Means 2008 Hypothalamic CaMKK2 contributes to the regulation of energy balance Cell Metab 7 377 388 18460329 10.1016/j.cmet.2008.02.011 1:CAS:528:DC%2BD1cXmtFeitbc%3D (Pubitemid 351598022)
-
(2008)
Cell Metabolism
, vol.7
, Issue.5
, pp. 377-388
-
-
Anderson, K.A.1
Ribar, T.J.2
Lin, F.3
Noeldner, P.K.4
Green, M.F.5
Muehlbauer, M.J.6
Witters, L.A.7
Kemp, B.E.8
Means, A.R.9
-
218
-
-
42649085394
-
The CAMplexities of Central Ghrelin
-
DOI 10.1016/j.cmet.2008.04.009, PII S1550413108001216
-
MW Sleeman E Latres 2008 The CAMplexities of central ghrelin Cell Metab 7 361 362 18460326 10.1016/j.cmet.2008.04.009 1:CAS:528:DC%2BD1cXmtFeitbg%3D (Pubitemid 351598032)
-
(2008)
Cell Metabolism
, vol.7
, Issue.5
, pp. 361-362
-
-
Sleeman, M.W.1
Latres, E.2
-
219
-
-
42949146633
-
Hypothalamic Fatty Acid Metabolism Mediates the Orexigenic Action of Ghrelin
-
DOI 10.1016/j.cmet.2008.03.006, PII S1550413108000776
-
M Lopez R Lage AK Saha D Perez-Tilve MJ Vazquez L Varela S Sangiao-Alvarellos S Tovar K Raghay S Rodriguez-Cuenca RM Deoliveira T Castaneda R Datta JZ Dong M Culler MW Sleeman CV Alvarez R Gallego CJ Lelliott D Carling MH Tschop C Dieguez A Vidal-Puig 2008 Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin Cell Metab 7 389 399 18460330 10.1016/j.cmet.2008.03.006 1:CAS:528:DC%2BD1cXmtFeiur4%3D (Pubitemid 351618114)
-
(2008)
Cell Metabolism
, vol.7
, Issue.5
, pp. 389-399
-
-
Lopez, M.1
Lage, R.2
Saha, A.K.3
Perez-Tilve, D.4
Vazquez, M.J.5
Varela, L.6
Sangiao-Alvarellos, S.7
Tovar, S.8
Raghay, K.9
Rodriguez-Cuenca, S.10
Deoliveira, R.M.11
Castaneda, T.12
Datta, R.13
Dong, J.Z.14
Culler, M.15
Sleeman, M.W.16
Alvarez, C.V.17
Gallego, R.18
Lelliott, C.J.19
Carling, D.20
Tschop, M.H.21
Dieguez, C.22
Vidal-Puig, A.23
more..
-
220
-
-
39749147110
-
Mechanisms of disease: Molecular and metabolic mechanisms of insulin resistance and β-cell failure in type 2 diabetes
-
DOI 10.1038/nrm2327, PII NRM2327
-
DM Muoio CB Newgard 2008 Mechanisms of disease: molecular and metabolic mechanisms of insulin resistance and beta-cell failure in type 2 diabetes Nat Rev Mol Cell Biol 9 193 205 18200017 10.1038/nrm2327 1:CAS:528: DC%2BD1cXitlGnurg%3D (Pubitemid 351301824)
-
(2008)
Nature Reviews Molecular Cell Biology
, vol.9
, Issue.3
, pp. 193-205
-
-
Muoio, D.M.1
Newgard, C.B.2
-
221
-
-
0035654626
-
Overfeeding rapidly induces leptin and insulin resistance
-
11723062 10.2337/diabetes.50.12.2786 1:CAS:528:DC%2BD3MXovVOhsrg%3D
-
J Wang S Obici K Morgan N Barzilai Z Feng L Rossetti 2001 Overfeeding rapidly induces leptin and insulin resistance Diabetes 50 2786 2791 11723062 10.2337/diabetes.50.12.2786 1:CAS:528:DC%2BD3MXovVOhsrg%3D
-
(2001)
Diabetes
, vol.50
, pp. 2786-2791
-
-
Wang, J.1
Obici, S.2
Morgan, K.3
Barzilai, N.4
Feng, Z.5
Rossetti, L.6
-
222
-
-
11144302579
-
Consumption of a high-fat diet alters the homeostatic regulation of energy balance
-
DOI 10.1016/j.physbeh.2004.07.026, PII S0031938404004111, Dietary Fat and Energy Balace-Myths and Facts
-
SC Woods DA D'Alessio P Tso PA Rushing DJ Clegg SC Benoit K Gotoh M Liu RJ Seeley 2004 Consumption of a high-fat diet alters the homeostatic regulation of energy balance Physiol Behav 83 573 578 15621062 10.1016/j.physbeh.2004.07. 026 1:CAS:528:DC%2BD2cXhtFCqtLjM (Pubitemid 40038507)
-
(2004)
Physiology and Behavior
, vol.83
, Issue.4
, pp. 573-578
-
-
Woods, S.C.1
D'Alessio, D.A.2
Tso, P.3
Rushing, P.A.4
Clegg, D.J.5
Benoit, S.C.6
Gotoh, K.7
Liu, M.8
Seeley, R.J.9
-
223
-
-
0033931981
-
Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity
-
10862798 10.1172/JCI9842 1:CAS:528:DC%2BD3cXkt1WqsLc%3D
-
K El-Haschimi DD Pierroz SM Hileman C Bjorbaek JS Flier 2000 Two defects contribute to hypothalamic leptin resistance in mice with diet-induced obesity J Clin Invest 105 1827 1832 10862798 10.1172/JCI9842 1:CAS:528: DC%2BD3cXkt1WqsLc%3D
-
(2000)
J Clin Invest
, vol.105
, pp. 1827-1832
-
-
El-Haschimi, K.1
Pierroz, D.D.2
Hileman, S.M.3
Bjorbaek, C.4
Flier, J.S.5
-
224
-
-
0024202693
-
Intracerebroventricular infusions of 3-OHB and insulin in a rat model of dietary obesity
-
3059829 1:CAS:528:DyaL1MXls1Cgug%3D%3D
-
K Arase JS Fisler NS Shargill DA York GA Bray 1988 Intracerebroventricular infusions of 3-OHB and insulin in a rat model of dietary obesity Am J Physiol 255 R974 R981 3059829 1:CAS:528:DyaL1MXls1Cgug%3D%3D
-
(1988)
Am J Physiol
, vol.255
-
-
Arase, K.1
Fisler, J.S.2
Shargill, N.S.3
York, D.A.4
Bray, G.A.5
-
225
-
-
33847319765
-
Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons
-
17339026 10.1016/j.cmet.2007.02.004 1:CAS:528:DC%2BD2sXjsF2qtLw%3D
-
PJ Enriori AE Evans P Sinnayah EE Jobst L Tonelli-Lemos SK Billes MM Glavas BE Grayson M Perello EA Nillni KL Grove MA Cowley 2007 Diet-induced obesity causes severe but reversible leptin resistance in arcuate melanocortin neurons Cell Metab 5 181 194 17339026 10.1016/j.cmet.2007.02.004 1:CAS:528:DC%2BD2sXjsF2qtLw%3D
-
(2007)
Cell Metab
, vol.5
, pp. 181-194
-
-
Enriori, P.J.1
Evans, A.E.2
Sinnayah, P.3
Jobst, E.E.4
Tonelli-Lemos, L.5
Billes, S.K.6
Glavas, M.M.7
Grayson, B.E.8
Perello, M.9
Nillni, E.A.10
Grove, K.L.11
Cowley, M.A.12
-
226
-
-
66149118129
-
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
-
19116375 10.1152/ajpendo.90377.2008 1:CAS:528:DC%2BD1MXlvFags7w%3D
-
K Posey DJ Clegg RL Printz J Byun GJ Morton A Vivekanandan-Giri S Pennathur DG Baskin JW Heinecke SC Woods MW Schwartz KD Niswender 2008 Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet Am J Physiol Endocrinol Metab 296 5 E1003 E1012 19116375 10.1152/ajpendo.90377.2008 1:CAS:528:DC%2BD1MXlvFags7w%3D
-
(2008)
Am J Physiol Endocrinol Metab
, vol.296
, Issue.5
-
-
Posey, K.1
Clegg, D.J.2
Printz, R.L.3
Byun, J.4
Morton, G.J.5
Vivekanandan-Giri, A.6
Pennathur, S.7
Baskin, D.G.8
Heinecke, J.W.9
Woods, S.C.10
Schwartz, M.W.11
Niswender, K.D.12
-
227
-
-
70349484212
-
MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity
-
19808018 10.1016/j.cmet.2009.08.013 1:CAS:528:DC%2BD1MXhsFKltL3K
-
A Kleinridders D Schenten AC Konner BF Belgardt J Mauer T Okamura FT Wunderlich R Medzhitov JC Bruning 2009 MyD88 signaling in the CNS is required for development of fatty acid-induced leptin resistance and diet-induced obesity Cell Metab 10 249 259 19808018 10.1016/j.cmet.2009.08.013 1:CAS:528: DC%2BD1MXhsFKltL3K
-
(2009)
Cell Metab
, vol.10
, pp. 249-259
-
-
Kleinridders, A.1
Schenten, D.2
Konner, A.C.3
Belgardt, B.F.4
Mauer, J.5
Okamura, T.6
Wunderlich, F.T.7
Medzhitov, R.8
Bruning, J.C.9
-
228
-
-
0035907302
-
Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4
-
11278967 10.1074/jbc.M011695200 1:CAS:528:DC%2BD3MXjvFGju78%3D
-
JY Lee KH Sohn SH Rhee D Hwang 2001 Saturated fatty acids, but not unsaturated fatty acids, induce the expression of cyclooxygenase-2 mediated through Toll-like receptor 4 J Biol Chem 276 16683 16689 11278967 10.1074/jbc.M011695200 1:CAS:528:DC%2BD3MXjvFGju78%3D
-
(2001)
J Biol Chem
, vol.276
, pp. 16683-16689
-
-
Lee, J.Y.1
Sohn, K.H.2
Rhee, S.H.3
Hwang, D.4
-
229
-
-
0347985272
-
Obesity-induced inflammatory changes in adipose tissue
-
14679172 1:CAS:528:DC%2BD3sXhtVSmtLrE
-
KE Wellen GS Hotamisligil 2003 Obesity-induced inflammatory changes in adipose tissue J Clin Invest 112 1785 1788 14679172 1:CAS:528:DC%2BD3sXhtVSmtLrE
-
(2003)
J Clin Invest
, vol.112
, pp. 1785-1788
-
-
Wellen, K.E.1
Hotamisligil, G.S.2
-
230
-
-
24944438230
-
Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus
-
DOI 10.1210/en.2004-1520
-
CT De Souza EP Araujo S Bordin R Ashimine RL Zollner AC Boschero MJ Saad LA Velloso 2005 Consumption of a fat-rich diet activates a proinflammatory response and induces insulin resistance in the hypothalamus Endocrinology 146 4192 4199 16002529 10.1210/en.2004-1520 1:CAS:528:DC%2BD2MXhtVGmurjK (Pubitemid 41324012)
-
(2005)
Endocrinology
, vol.146
, Issue.10
, pp. 4192-4199
-
-
De Souza, C.T.1
Araujo, E.P.2
Bordin, S.3
Ashimine, R.4
Zollner, R.L.5
Boschero, A.C.6
Saad, M.J.A.7
Velloso, L.A.8
-
231
-
-
66149118129
-
Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet
-
19116375 10.1152/ajpendo.90377.2008 1:CAS:528:DC%2BD1MXlvFags7w%3D
-
KA Posey DJ Clegg RL Printz J Byun GJ Morton A Vivekanandan-Giri S Pennathur DG Baskin JW Heinecke SC Woods MW Schwartz KD Niswender 2009 Hypothalamic proinflammatory lipid accumulation, inflammation, and insulin resistance in rats fed a high-fat diet Am J Physiol Endocrinol Metab 296 E1003 E1012 19116375 10.1152/ajpendo.90377.2008 1:CAS:528:DC%2BD1MXlvFags7w%3D
-
(2009)
Am J Physiol Endocrinol Metab
, vol.296
-
-
Posey, K.A.1
Clegg, D.J.2
Printz, R.L.3
Byun, J.4
Morton, G.J.5
Vivekanandan-Giri, A.6
Pennathur, S.7
Baskin, D.G.8
Heinecke, J.W.9
Woods, S.C.10
Schwartz, M.W.11
Niswender, K.D.12
-
232
-
-
77950532905
-
Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism
-
20231445 10.1073/pnas.1001796107
-
BF Belgardt J Mauer FT Wunderlich MB Ernst M Pal G Spohn HS Bronneke S Brodesser B Hampel AC Schauss JC Bruning 2010 Hypothalamic and pituitary c-Jun N-terminal kinase 1 signaling coordinately regulates glucose metabolism Proc Natl Acad Sci USA 107 13 6028 6033 20231445 10.1073/pnas.1001796107
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, Issue.13
, pp. 6028-6033
-
-
Belgardt, B.F.1
Mauer, J.2
Wunderlich, F.T.3
Ernst, M.B.4
Pal, M.5
Spohn, G.6
Bronneke, H.S.7
Brodesser, S.8
Hampel, B.9
Schauss, A.C.10
Bruning, J.C.11
-
233
-
-
58849149821
-
Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: Implications for the pathogenesis of obesity
-
19144836 10.1523/JNEUROSCI.2760-08.2009 1:CAS:528:DC%2BD1MXhtVKrurw%3D
-
M Milanski G Degasperi A Coope J Morari R Denis DE Cintra DM Tsukumo G Anhe ME Amaral HK Takahashi R Curi HC Oliveira JB Carvalheira S Bordin MJ Saad LA Velloso 2009 Saturated fatty acids produce an inflammatory response predominantly through the activation of TLR4 signaling in hypothalamus: implications for the pathogenesis of obesity J Neurosci 29 359 370 19144836 10.1523/JNEUROSCI.2760-08.2009 1:CAS:528:DC%2BD1MXhtVKrurw%3D
-
(2009)
J Neurosci
, vol.29
, pp. 359-370
-
-
Milanski, M.1
Degasperi, G.2
Coope, A.3
Morari, J.4
Denis, R.5
Cintra, D.E.6
Tsukumo, D.M.7
Anhe, G.8
Amaral, M.E.9
Takahashi, H.K.10
Curi, R.11
Oliveira, H.C.12
Carvalheira, J.B.13
Bordin, S.14
Saad, M.J.15
Velloso, L.A.16
-
234
-
-
57849115277
-
Endoplasmic reticulum stress plays a central role in development of leptin resistance
-
19117545 10.1016/j.cmet.2008.12.004 1:CAS:528:DC%2BD1MXptFWquw%3D%3D
-
L Ozcan AS Ergin A Lu J Chung S Sarkar D Nie MG Myers Jr U Ozcan 2009 Endoplasmic reticulum stress plays a central role in development of leptin resistance Cell Metab 9 35 51 19117545 10.1016/j.cmet.2008.12.004 1:CAS:528:DC%2BD1MXptFWquw%3D%3D
-
(2009)
Cell Metab
, vol.9
, pp. 35-51
-
-
Ozcan, L.1
Ergin, A.S.2
Lu, A.3
Chung, J.4
Sarkar, S.5
Nie, D.6
Myers Jr., M.G.7
Ozcan, U.8
-
235
-
-
52949096557
-
Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity
-
18854155 10.1016/j.cell.2008.07.043 1:CAS:528:DC%2BD1cXht1Gkt7nP
-
X Zhang G Zhang H Zhang M Karin H Bai D Cai 2008 Hypothalamic IKKbeta/NF-kappaB and ER stress link overnutrition to energy imbalance and obesity Cell 135 61 73 18854155 10.1016/j.cell.2008.07.043 1:CAS:528: DC%2BD1cXht1Gkt7nP
-
(2008)
Cell
, vol.135
, pp. 61-73
-
-
Zhang, X.1
Zhang, G.2
Zhang, H.3
Karin, M.4
Bai, H.5
Cai, D.6
-
236
-
-
70349650001
-
Enhanced hypothalamic glucose sensing in obesity: Alteration of redox signaling
-
19581415 10.2337/db09-0110 1:CAS:528:DC%2BD1MXht1yku7vO
-
AL Colombani L Carneiro A Benani A Galinier T Jaillard T Duparc G Offer A Lorsignol C Magnan L Casteilla L Penicaud C Leloup 2009 Enhanced hypothalamic glucose sensing in obesity: alteration of redox signaling Diabetes 58 2189 2197 19581415 10.2337/db09-0110 1:CAS:528:DC%2BD1MXht1yku7vO
-
(2009)
Diabetes
, vol.58
, pp. 2189-2197
-
-
Colombani, A.L.1
Carneiro, L.2
Benani, A.3
Galinier, A.4
Jaillard, T.5
Duparc, T.6
Offer, G.7
Lorsignol, A.8
Magnan, C.9
Casteilla, L.10
Penicaud, L.11
Leloup, C.12
-
237
-
-
33646582664
-
Hypothalamic mTOR signaling regulates food intake
-
DOI 10.1126/science.1124147
-
D Cota K Proulx KA Smith SC Kozma G Thomas SC Woods RJ Seeley 2006 Hypothalamic mTOR signaling regulates food intake Science 312 927 930 16690869 10.1126/science.1124147 1:CAS:528:DC%2BD28Xktlyhs7Y%3D (Pubitemid 43727328)
-
(2006)
Science
, vol.312
, Issue.5775
, pp. 927-930
-
-
Cota, D.1
Proulx, K.2
Blake Smith, K.A.3
Kozma, S.C.4
Thomas, G.5
Woods, S.C.6
Seeley, R.J.7
-
238
-
-
34249680883
-
Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms
-
DOI 10.2337/db07-0123
-
Y Zhang K Guo RE LeBlanc D Loh GJ Schwartz YH Yu 2007 Increasing dietary leucine intake reduces diet-induced obesity and improves glucose and cholesterol metabolism in mice via multimechanisms Diabetes 56 1647 1654 17360978 10.2337/db07-0123 1:CAS:528:DC%2BD2sXmtlKhs70%3D (Pubitemid 46842599)
-
(2007)
Diabetes
, vol.56
, Issue.6
, pp. 1647-1654
-
-
Zhang, Y.1
Guo, K.2
LeBlanc, R.E.3
Loh, D.4
Schwartz, G.J.5
Yu, Y.-H.6
|