Interleukin-1β-induced alteration in a β-cell phenotype can reduce cellular sensitivity to conditions that cause necrosis but not to cytokine- induced apoptosis

Diabetes

Volumn 49, Issue 3, 2000, Pages 340-345

  Ling, Zhidong ^a   Van De Casteele, Mark ^a   Eizirik, Décio L ^a   Pipeleers, Daniel G ^a,b  

^a FACULTY OF MEDICINE AND PHARMACY   (Belgium)

^b VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

Author keywords

[No Author keywords available]

Indexed keywords

ALLOXAN; CYTOKINE; GLUCOSE TRANSPORTER; HEAT SHOCK PROTEIN 70; INSULIN; INTERLEUKIN 1BETA; MANGANESE SUPEROXIDE DISMUTASE; NITRIC OXIDE; STREPTOZOCIN; TRANSCRIPTION FACTOR; 3 (3,4 DICHLOROPHENYL) 1,2,3,4 OXATRIAZOLE 5 IMINE; INTERLEUKIN 1; NITRIC OXIDE DONOR; PROTEIN; TRIAZOLE DERIVATIVE;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; CYTOKINE RELEASE; HOMEOBOX; HOMEOSTASIS; MALE; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ANIMAL; DOSE RESPONSE; DRUG EFFECT; METABOLISM; NECROSIS; OSMOLARITY; PANCREAS ISLET; PATHOLOGY; PHENOTYPE; PHYSIOLOGY; WISTAR RAT;

ALLOXAN; ANIMALS; APOPTOSIS; CYTOKINES; DOSE-RESPONSE RELATIONSHIP, DRUG; INTERLEUKIN-1; ISLETS OF LANGERHANS; MALE; NECROSIS; NITRIC OXIDE DONORS; OSMOLAR CONCENTRATION; PHENOTYPE; PROTEINS; RATS; RATS, WISTAR; STREPTOZOCIN; TRIAZOLES;

EID: 0033625664     PISSN: 00121797     EISSN: None     Source Type: Journal    
DOI: 10.2337/diabetes.49.3.340     Document Type: Article

References (39)

1. Gepts W: Pathologic anatomy of the pancreas in juvenile diabetes mellitus. Diabetes 14:619-633, 1965
2. Pipeleers D, Van De Winkel M: Pancreatic β-cells possess defense mechanisms against cell-specific toxicity. Proc Natl Acad Sci U S A 83:5267-5271, 1986
3. Rabinovitch A: An update on cytokines in the pathogenesis of insulin-dependent diabetes mellitus. Diabetes Metab Rev 14:129-151, 1998
4. Rabinovitch A: Roles of cytokines in IDDM pathogenesis and islet β-cell destruction. Diabetes Rev 1:215-240, 1993
5. Mandrup-Poulsen T: The role of interleukin-1 in the pathogenesis of IDDM. Diabetologia 39:1005-1020, 1996
6. Ling Z, In't Veld PA, Pipeleers DG: Interaction of interleukin-1 with islet β-cells: distinction between indirect, specific cytotoxicity and direct, specific functional suppression. Diabetes 42:56-65, 1993
7. Ling Z, Chen MC, Smismans A, Pavlovic D, Schuit F, Eizirik DL, Pipeleers DG: Intercellular differences in interleukin 1-induced suppression of insulin synthesis and stimulation of non-insulin protein synthesis by rat pancreatic β-cells. Endocrinology 139:1540-1545, 1998
8. Southern C, Schulster D, Green IC: Inhibition of insulin secretion by interleukin-1 beta and tumour necrosis factor-alpha via an L-arginine-dependent nitric oxide generating mechanism. FEBS Lett 276:42-44, 1990
9. Corbett JA, McDaniel ML: Does nitric oxide mediate autoimmune destruction of β-cells? Possible therapeutic interventions in IDDM. Diabetes 4:897-903, 1992
10. Corbett JA, McDaniel ML: Intraislet release of interleukin 1 inhibits beta cell function by inducing beta cell expression of inducible nitric oxide synthase. J Exp Med 181:559-568, 1995
11. Eizirik DL, Welsh M, Strandell E, Welsh N, Sandler S: Interleukin-1 beta depletes insulin messenger ribonucleic acid and increases the heat shock protein hsp70 in mouse pancreatic islets without impairing the glucose metabolism. Endocrinology 127:2290-2297, 1990
12. Helqvist S, Polla BS, Johannesen J, Nerup J: Heat shock protein induction in rat pancreatic islets by recombinant human interleukin 1 beta. Diabetologia 34:150-156, 1991
13. Borg LA, Cagliero E, Sandler S, Welsh N, Eizirik DL: Interleukin-1 beta increases the activity of superoxide dismutase in rat pancreatic islets. Endocrinology 130:2851-2857, 1992
14. Andersen HU, Larsen PM, Fey SJ, Karlsen AE, Mandrup-Poulsen T, Nerup J: Two-dimensional gel electrophoresis of rat islet proteins: interleukin 1β-induced changes in protein expression are reduced by L-arginine depletion and nicotinamide. Diabetes 44:400-407, 1995
15. Strandell E, Buschard K, Saldeen J, Welsh N: Interleukin-1β induces the expression of hsp70, heme oxygenase and Mn-SOD in FACS-purified rat islet β-cells, but not in α-cells. Immunol Lett 48:145-148, 1995
16. Motterlini R, Foresti R, Intaglietta M, Winslow RM: NO-mediated activation of heme oxygenase: endogenous cytoprotection against oxidative stress to endothelium. Am J Physiol 270:H107-H114, 1996
17. Kim YM, de Vera ME, Watkins SC, Billiar TR: Nitric oxide protects cultured rat hepatocytes from tumor necrosis factor-γ-induced apoptosis by inducing heat shock protein 70 expression. J Biol Chem 272:1402-1411, 1997
18. Llesuy SF, Tomaro ML: Heme oxygenase and oxidative stress: evidence of involvement of bilirubin as physiological protector against oxidative damage. Biochim Biophys Acta 1223:9-14, 1994
19. Otterhein LE, Kolls JK, Mantell LL, Cook JL, Alam J, Choi AM: Exogenous administration of heme oxygenase-1 by gene transfer provides protection against hyperoxia-induced lung injury. J Clin Invest 103:1047-1054, 1999
20. Bellmann K, Jaattela M, Wissing D, Burkart V, Kolb H: Heat shock protein hsp70 overexpression confers resistance against nitric oxide. FEBS Lett 391:185-188, 1996
21. Hohmeier HE, Thigpen A, Tran VV, Davis R, Newgard CB: Stable expression of manganese superoxide dismutase (MnSOD) in insulinoma cells prevents IL-1beta-induced cytotoxicity and reduces nitric oxide production. J Clin Invest 101:1811-1820, 1998
22. Pipeleers DG, In't Veld PA, Van De Winkel M, Maes E, Schuit FC, Gepts W: A new in vitro model for the study of pancreatic α and β cells. Endocrinology 117:806-816, 1985
23. Ling Z, Hannaert JC, Pipeleers D: Effect of nutrients, hormones and serum on survival of rat islet beta cells in culture. Diabetologia 37:15-21, 1994
24. Schuit FC, Pipeleers DG: Regulation of adenosine 3′,5′-monophosphate levels in the pancreatic B cell. Endocrinology 117:834-840, 1985
25. Hoorens A, Pipeleers D: Nicotinamide protects human beta cells against chemically-induced necrosis, but not against cytokine-induced apoptosis. Diabetologia 42:55-59, 1999
26. Pipeleers DG, Schuit FC, In't Veld PA, Maes E, Hooghe-Peters E, Van De Winkel M, Gepts W: Interplay of nutrients and hormones in the regulation of insulin release. Endocrinology 117:824-833, 1985
27. 15H]nitrate in biological fluids. Anal Biochem 126:131-138, 1982
28. Munim A, Asayama K, Dobashi K, Suzuki K, Kawaoi A, Kato K: Immunohistochemical localization of superoxide dismutases in fetal and neonatal rat tissues. J Histochem Cytochem 40:1705-1713, 1992
29. Alarcòn C, Lincoln B, Rhodes CJ: The biosynthesis of the subtilisin-related pro-protein convertase PC3, but not that of the PC2 convertase, is regulated by glucose in parallel to proinsulin biosynthesis in rat pancreatic islets. J Biol Chem 268:4276-4280, 1993
30. Serup P, Jensen J, Andersen FG, Jorgensen MC, Blume N, Holst JJ, Madsen OD: Induction of insulin and islet amyloid polypeptide production in pancreatic islet glucagonoma cells by insulin promoter factor 1. Proc Natl Acad Sci U S A 93:9015-9020, 1996
31. Waeber G, Thompson N, Nicod P, Bonny C: Transcriptional activation of the GLUT2 gene by the IPF-1/STF-1/IDX-1 homeobox factor. Mol Endocrinol 10:1327-1334, 1996
32. Watada H, Kajimoto Y, Miyagawa J, Hanafusa T, Hamaguchi K, Matsuoka T, Yamamoto K, Matsuzawa Y, Kawamori R, Yamasaki Y: PDX-1 induces insulin and glucokinase gene expressions in αTC1 clone 6 cells in the presence of beta-cellulin. Deabetes 45:1826-1831, 1996
33. Sander M, German MS: The beta cell transcription factors and development of the pancreas. J Mol Med 75:327-340, 1997
34. Madsen OD, Jensen J, Petersen HV, Pedersen EE, Oster A. Andersen FG, Jorgensen MC, Jensen PB, Larsson LI, Serup P: Transcription factors contributing to the pancreatic beta-cell phenotype. Horm Metab Res 29:265-270, 1997
35. De Vos A, Heimberg H, Quartier E, Huypens P, Bouwens L, Pipeleers D, Schuit F: Human and rat beta cells differ in glucose transporter but not in glucokinase gene expression. J Clin Invest 96:2489-2495, 1995
36. Schnedl WJ, Ferber S, Johnson JH, Newgard CB: STZ transport and cytotoxicity: specific enhancement in GLUT2-expressing cells. Diabetes 43:1326-1333, 1994
37. Bellmann K, Wenz A, Radons J, Burkart V, Kleemann R, Kolb H: Heat shock induces resistance in rat pancreatic islet cells against nitric oxide, oxygen radicals and streptozotocin toxicity in vitro. J Clin Invest 95:2840-2845, 1995
38. Fridovich I: Superoxide radical and superoxide dismutases. Annu Rev Biochem 64:97-112, 1995
39. Wink DA, Hanbauer I, Krishna MC, De Graff W, Gamson J, Mitchell JB: Nitric oxide protects against cellular damage and cytotoxicity from reactive oxygen species. Proc Natl Acad Sci U S A 90:9813-9817, 1993