High glucose induces IL-1β expression in human monocytes: Mechanistic insights

American Journal of Physiology - Endocrinology and Metabolism

Volumn 293, Issue 1, 2007, Pages

  Dasu, Mohan R ^b   Devaraj, Sridevi ^b   Jialal, Ishwarlal ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NONE

Author keywords

Diabetes; Interleukin 1 ; p38 phosphorylation; Protein kinase C

Indexed keywords

1,4 DIAMINO 1,4 BIS(2 AMINOPHENYLTHIO) 2,3 DICYANOBUTADIENE; 4 (4 FLUOROPHENYL) 2 (4 METHYLSULFINYLPHENYL) 5 (4 PYRIDYL)IMIDAZOLE; BAY 11 7085; CELL PROTEIN; ENZYME INHIBITOR; GLUCOSE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; INTERLEUKIN 1BETA; LY 379196; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; MITOGEN ACTIVATED PROTEIN KINASE P38; PROTEIN KINASE C; PROTEIN KINASE C ALPHA; PROTEIN P47; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE OXIDASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

ARTICLE; CELL CULTURE; ENZYME LINKED IMMUNOSORBENT ASSAY; GLUCOSE INTAKE; HUMAN; HUMAN CELL; MONOCYTE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING;

CELLS, CULTURED; DOSE-RESPONSE RELATIONSHIP, DRUG; GENE EXPRESSION REGULATION; GLUCOSE; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1BETA; MAP KINASE SIGNALING SYSTEM; MODELS, BIOLOGICAL; MONOCYTES; NF-KAPPA B; PROTEIN KINASE C; RNA, SMALL INTERFERING; TIME FACTORS;

EID: 34547119919     PISSN: 01931849     EISSN: 15221555     Source Type: Journal    
DOI: 10.1152/ajpendo.00718.2006     Document Type: Article

References (50)

1. Aljada A, Friedman J, Ghanim H, Mohanty P, Hofmeyer D, Chaudhuri A, Dandona P. Glucose ingestion induces an increase in intranuclear NF-βB, a fall in cellular inhibitor βB, and an increase in TNF-alpha mRNA by mononuclear cells in healthy human subjects. Metabolism 55: 1177-1185, 2006.
2. Aljada A, Ghanim H, Dandona P. Translocation of p47phox and activation of NADPH oxidase in mononuclear cells. Methods Mol Biol 196: 99-103, 2002.
3. Arondel J, Singer M, Matsukawa A, Zychlinsky A, Sansonetti PJ. Increased interleukin-1 (IL-1) and imbalance between IL-1 and IL-1 receptor antagonist during acute inflammation in experimental Shigellosis. Infect Immun 67: 6056-6066, 1999.
4. Asakawa H, Miyagawa J, Hanafusa T, Kuwajima M, Matsuzawa Y. High glucose and hyperosmolarity increase secretion of interleukin-1β incultured human aortic endothelial cells. J Diabetes Complications 11: 176-179, 1997.
5. Baeuerle PA. The inducible transcription activator NF-κB: regulation by distinct protein subunits. Biochim Biophys Acta 1072: 63-80, 1991.
6. Bevilacqua MP, Pober JS, Majeau GR, Cotran RS, Gimbrone MA. Interleukin 1 (IL-1) induces biosynthesis and cell surface expression of procoagulant activity in human vascular endothelial cells. J Exp Med 163: 1595-1600, 1984.
7. Bevilacqua M, Gimbrone M. Inducible cell functions in inflammation and coagulation. Semin Thromb Hemost 138: 425-433, 1987.
8. Bevilacqua MP, Pober JS, Wheeler ME, Cotran RS, Gimbrone MA. Interleukin 1 acts on cultured human vascular endothelium to increase the adhesion of polymorphonuclear leukocytes, monocytes, and related leukocyte cell lines. J Clin Invest 76: 2003-2008, 1985.
9. Brownlee M. Lilly Lecture 1993. Glycation and diabetic complications. Diabetes 43: 826-841, 1994.
10. Devaraj S, Venugopal SK, Singh U, Jialal I. Hyperglycemia induces monocytic release of interleukin-6 via induction of protein kinase C-α and -β. Diabetes 54: 85-91, 2005.
11. Devaraj S, Glaser N, Griffen S, Wang-Polagruto J, Miguelino E, Jialal I. Increased monocytic activity and biomarkers of inflammation in patients with type 1 diabetes. Diabetes 55: 774-779, 2006.
12. Dinarello CA. Interleukin-1β. Crit Care Med 33: S460-S462, 2005.
13. Donahue R, Abbott R, Reed D, Yano K. Postchallenge glucose concentration and coronary heart disease in men of Japanese ancestry. Diabetes 36: 689-692, 1987.
14. Eizirik DL, Mandrup-Poulsen T. A choice of death-the signal-transduction of immune-mediated β-cell apoptosis. Diabetologia 44: 2115-2133, 2001.
15. Galea J, Armstrong J, Gadsdon P, Holden H, Francis SE, Holt CM. IL-1β in coronary arteries patients with ishcemic heart disease. Arterioscler Thromb Vasc Biol 16: 1000-1006, 1996.
16. Ghanim H, Aljada A, Hofmeyer D, Syed T, Mohanty P, Dandona P. Circulating mononuclear cells in the obese are in a proinflammatory state. Circulation 110: 1564-1571, 2004.
17. Hansson GK. Inflammation, atherosclerosis, and coronary disease. N Engl J Med 352: 1685-1695, 2005.
18. Hill H, Hogan N, Rallison M, Santo JI, Charette RP, Kitahara M. Functional and metabolic abnormalities of diabetic monocytes. Adv Exp Med Biol 69: 621-628, 1980.
19. Hiramatsu K, Rosen H, Heinecke J, Wolfbauer G, Chait A. Superoxide initiates oxidation of low density lipoprotein by human monocytes. Arteriosclerosis 7: 55-60, 1987.
20. Hofmann MA, Schiekofer S, Kanitz M, Klevesath MS, Joswig M, Lee V, Morcos M, Tritschler H, Ziegler R, Wahl P, Bierhaus A, Nawroth PP. Insufficient glycemic control increases NF-κB binding activity in peripheral blood mononuclear cells isolated from patients with type 1 diabetes. Diabetes Care 21: 1310-1316, 1998.
21. Igarashi M, Wakasaki H, Takahara N, Ishii H, Jiang ZY, Yamauchi T, Kuboki K, Meier M, Rhodes CJ, King GL. Glucose or diabetes activates p38 mitogen-activated protein kinase via different pathways. J Clin Invest 103: 185-195, 1999.
22. Jain SK, Kannan K, Lim G, McVie R, Bocchini JA Jr. Hyperketonemia increases tumor necrosis factor-α secretion in cultured U937 monocytes and Type 1 diabetic patients and is apparently mediated by oxidative stress and cAMP deficiency. Diabetes 51: 2287-2293, 2002.
23. Kadri-Hassani N, Leger CL, Descomps B. The fatty acid bimodal action on superoxide production by human adherent monocytes under phorbol 12-myristate 13-acetate or diacylglycerol activation can be explained by the modulation of protein kinase C and p47phox translocation. J Biol Chem 270: 15111-15118, 1995.
24. Kirii H, Niwa T, Yamada Y, Wada H, Saito K, Iwakura Y, Asano M, Moriwaki H, Seishima M. Lack of interleukin-1β decreases the severity of atherosclerosis in ApoE-deficient mice. Arterioscler Thromb Vasc Biol 23: 656-660, 2003.
25. Kitahara M, Eyre H, Lynch R, Rallison ML, Hill HR. Metabolic activity of diabetic monocytes. Diabetes 29: 251-256, 1980.
26. Kowluru RA, Odenbach S. Role of interleukin-1β in the pathogenesis of diabetic retinopathy. Br J Ophthalmol 88: 1343-1347, 2004.
27. Koya D, King GL. Protein kinase C activation and the development of diabetic complications. Diabetes 47: 859-866, 1998.
28. Kuusisto J, Mykkanen L, Pyorala K, Laakso M. NIDDM and its metabolic control predict coronary heart disease in elderly subjects. Diabetes 43: 960-967, 1994.
29. Lenardo MJ, Baltimore D. NF-κB: a pleiotropic mediator of inducible and tissue-specific gene control. Cell 58: 227-229, 1989.
30. Libby P, Hansson GK. Involvement of the immune system in human atherogenesis: current knowledge and unanswered questions. Lab Invest 64: 5-15, 1991.
31. Livak KJ, Schmittgen TD. Analysis of relative gene expression data using real-time quantitative PCR and the 2-CT method. Methods 25: 402-408, 2001.
32. Lyons T. Glycation and oxidation: a role in the pathogenesis of atherosclerosis. Am J Cardiol 71: 26B-31B, 1993.
33. Maedler K, Sergeev P, Ris F, Oberholzer J, Joller-Jemelka HI, Spinas GA, Kaiser N, Halban PA, Donath MY. Glucose-induced beta cell production of IL-1β contributes to glucotoxicity in human pancreatic islets. J Clin Invest 110: 851-860, 2002.
34. Maziere C, Barbu V, Auclair M, Maziere JC. Interleukin 1 stimulates cholesterol esterification and cholesterol deposition in J774 monocytesmacrophages. Biochim Biophys Acta 1300: 30-34, 1996.
35. McGill H Jr, McMahan A, Malcom G, Oalmann MC, Strong JP. Relation of glycohemoglobin and adiposity to atherosclerosis in youth. Pathobiological Determinants of Atherosclerosis in Youths (PDAY) Research Group. Arterioscler Thromb Vasc Biol 15: 431-440, 1995.
36. Mohanty P, Hamouda W, Garg R, Aljada A, Ghanim H, Dandona P. Glucose challenge stimulates reactive oxygen species (ROS) by leucocytes. J Clin Endocrinol Metab 85: 2970-2973, 2000.
37. Nishikawa T, Edelstein D, Du XL, Yamagishi S, Matsumura T, Kaneda Y, Yorek MA, Beebe D, Oates PJ, Hammes HP, Giardino I, Brownlee M. Normalizing mitochondrial superoxide production blocks three pathways of hyperglycemic damage. Nature 404: 787-790, 2000.
38. Orlinska U, Newton RC. Role of glucose in IL-1β production by lipopolysaccharide activated human monocytes. J Cell Physiol 157: 201-209, 1993.
39. Perrier S, Darakhshan F, Hajduch E. IL-1 receptor antagonist in metabolic diseases: Dr. Jekyll or Mr. Hyde? FEBS Lett 580: 6289-6294, 2006.
40. Raines EW, Dower SK, Ross R. Interleukin-1 mitogenic activity for fibroblasts and smooth muscle cells is due to PDGF-AA. Science 243: 393-395, 1989.
41. Ruderman NB, Williamson JR, Brownlee M. Glucose and diabetic vascular disease. FASEB J 6: 2905-2914, 1992.
42. Schreiber E, Matthias P, Müller MM, Schaffner W. Rapid detection of octamer binding proteins with "mini-extracts," prepared from a small number of cells. Nucleic Acids Res 17: 6419, 1989.
43. Shanmugam N, Reddy MA, Guha M, Natarajan R. High glucoseinduced expression of proinflammatory cytokine and chemokine genes in monocytic cells. Diabetes 52: 1256-1264, 2003.
44. Shashkin PN, Jain N, Miller YI, Rissing BA, Huo Y, Keller SR, Vandenhoff GE, Nadler JL, McIntyre TM. Insulin and glucose play a role in foam cell formation and function. Cardiovasc Diabetol 20: 5-13, 2006.
45. Srinivasan S, Bolick DT, Hatley ME, Natarajan R, Reilly KB, Yeh M, Chrestensen C, Sturgill TW, Hedrick CC. Glucose regulates IL-8 production in aortic endothelial cells through activation of the p38 mitogen-activated protein kinase pathway in diabetes. J Biol Chem 279: 31930-31936, 2004.
46. Turner R, Millns H, Neil H, Stratton IM, Manley SE, Matthews DR, Holman RR. Risk factors for coronary artery disease in non-insulin dependent diabetes mellitus: UK Prospective Diabetes Study. Br Med J 316: 823-828, 1998.
47. Venugopal SK, Devaraj S, Yang T, Jialal I. α-Tocopherol decreases superoxide anion release in human monocytes under hyperglycemic conditions via inhibition of protein kinase C-α. Diabetes 51: 3049-3054, 2002.
48. Vlassara H, Bucala R, Sturcker L. Pathogenic effects of advanced glycosylation: biochemical, biologic, and clinical implications for diabetes and aging. Lab Invest 70: 138-151, 1994.
49. Wolff S, Jiang ZY, Hunt J. Protein glycation and oxidative stress in diabetes mellitus and aging. Free Radic Biol Med 10: 339-352, 1991.
50. Yamakawa T, Eguchi S, Matsumoto T, Yamakawa Y, Numaguchi K, Miyata I, Reynolds CM, Motley ED, Inagami T. Intracellular signaling in rat cultured vascular smooth muscle cells: roles of nuclear factor-κB and p38 MAP kinase on TNF-α production. Endocrinology 140: 3562-3572, 1999.