-
1
-
-
4344577124
-
-
Am. J. Trop. Med. Hyg.
-
Breman, J.G., Alilio, M.S., and Mills, A. (2004) Conquering the intolerable burden of malaria: what's new, what's needed: a summary. Am. J. Trop. Med. Hyg., 71, 1-15.
-
(2004)
Conquering the intolerable burden of malaria: what's new, what's needed: a summary
, vol.71
, pp. 1-15
-
-
Breman, J.G.1
Alilio, M.S.2
Mills, A.3
-
2
-
-
40149090171
-
Comparison of all-cause and malaria-specific mortality from two West African countries with different malaria transmission patterns
-
Ndugwa, R.P., Ramroth, H., Muller, O., Jasseh, M., Sie, A., Kouyate, B., Greenwood, B. et al. (2008) Comparison of all-cause and malaria-specific mortality from two West African countries with different malaria transmission patterns. Malar. J., 7, 15.
-
(2008)
Malar. J.
, vol.7
, pp. 15
-
-
Ndugwa, R.P.1
Ramroth, H.2
Muller, O.3
Jasseh, M.4
Sie, A.5
Kouyate, B.6
Greenwood, B.7
-
3
-
-
0037034017
-
The pathogenic basis of malaria
-
Miller, L.H., Baruch, D.I., Marsh, K., and Doumbo, O.K. (2002) The pathogenic basis of malaria. Nature, 415, 673-679.
-
(2002)
Nature
, vol.415
, pp. 673-679
-
-
Miller, L.H.1
Baruch, D.I.2
Marsh, K.3
Doumbo, O.K.4
-
4
-
-
19444386445
-
Free heme toxicity and its detoxification systems in human
-
Kumar, S. and Bandyopadhyay, U. (2005) Free heme toxicity and its detoxification systems in human. Toxicol. Lett., 157, 175-188.
-
(2005)
Toxicol. Lett.
, vol.157
, pp. 175-188
-
-
Kumar, S.1
Bandyopadhyay, U.2
-
5
-
-
0028211978
-
Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway
-
Gluzman, I.Y., Francis, S.E., Oksman, A., Smith, C.E., Duffin, K.L., and Goldberg, D.E. (1994) Order and specificity of the Plasmodium falciparum hemoglobin degradation pathway. J. Clin. Invest., 93, 1602-1608.
-
(1994)
J. Clin. Invest.
, vol.93
, pp. 1602-1608
-
-
Gluzman, I.Y.1
Francis, S.E.2
Oksman, A.3
Smith, C.E.4
Duffin, K.L.5
Goldberg, D.E.6
-
6
-
-
0023201135
-
Comparison of proteases from chloroquinesensitive and chloroquineresistant strains of Plasmodium falciparum
-
Vander Jagt, D.L., Hunsaker, L.A., and Campos, N.M. (1987) Comparison of proteases from chloroquinesensitive and chloroquineresistant strains of Plasmodium falciparum. Biochem. Pharmacol., 36, 3285-3291.
-
(1987)
Biochem. Pharmacol.
, vol.36
, pp. 3285-3291
-
-
Vander Jagt, D.L.1
Hunsaker, L.A.2
Campos, N.M.3
-
7
-
-
0041345739
-
Identification and characterization of heme-interacting proteins in the malaria parasite, Plasmodium falciparum
-
Campanale, N., Nickel, C., Daubenberger, C.A., Wehlan, D.A., Gorman, J.J., Klonis, N., Becker, K. et al. (2003) Identification and characterization of heme-interacting proteins in the malaria parasite, Plasmodium falciparum. J. Biol. Chem., 278, 27354-27361.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 27354-27361
-
-
Campanale, N.1
Nickel, C.2
Daubenberger, C.A.3
Wehlan, D.A.4
Gorman, J.J.5
Klonis, N.6
Becker, K.7
-
8
-
-
0038312099
-
The treatment of Plasmodium falciparuminfected erythrocytes with chloroquine leads to accumulation of ferriprotoporphyrin IX bound to particular parasite proteins and to the inhibition of the parasite's 6-phosphogluconate dehydrogenase
-
Famin, O. and Ginsburg, H. (2003) The treatment of Plasmodium falciparuminfected erythrocytes with chloroquine leads to accumulation of ferriprotoporphyrin IX bound to particular parasite proteins and to the inhibition of the parasite's 6-phosphogluconate dehydrogenase. Parasite, 10, 39-50.
-
(2003)
Parasite
, vol.10
, pp. 39-50
-
-
Famin, O.1
Ginsburg, H.2
-
9
-
-
0019355321
-
Mechanism of hemolysis induced by ferriprotoporphyrin IX
-
Chou, A.C. and Fitch, C.D. (1981) Mechanism of hemolysis induced by ferriprotoporphyrin IX. J. Clin. Invest., 68, 672-677.
-
(1981)
J. Clin. Invest.
, vol.68
, pp. 672-677
-
-
Chou, A.C.1
Fitch, C.D.2
-
10
-
-
0025043651
-
Hemin-promoted peroxidationof red cell cytoskeletal proteins
-
Solar, I., Dulitzky, J., and Shaklai, N. (1990) Hemin-promoted peroxidationof red cell cytoskeletal proteins. Arch. Biochem. Biophys., 283, 81-89.
-
(1990)
Arch. Biochem. Biophys.
, vol.283
, pp. 81-89
-
-
Solar, I.1
Dulitzky, J.2
Shaklai, N.3
-
11
-
-
0027430639
-
Origin of reactive oxygen species in erythrocytes infected with Plasmodium falciparum
-
Atamna, H. and Ginsburg, H. (1993) Origin of reactive oxygen species in erythrocytes infected with Plasmodium falciparum. Mol. Biochem. Parasitol., 61, 231-241.
-
(1993)
Mol. Biochem. Parasitol.
, vol.61
, pp. 231-241
-
-
Atamna, H.1
Ginsburg, H.2
-
12
-
-
1242316941
-
Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions
-
Becker, K., Tilley, L., Vennerstrom, J.L., Roberts, D., Rogerson, S., and Ginsburg, H. (2004) Oxidative stress in malaria parasite-infected erythrocytes: host-parasite interactions. Int. J. Parasitol., 34, 163-189.
-
(2004)
Int. J. Parasitol.
, vol.34
, pp. 163-189
-
-
Becker, K.1
Tilley, L.2
Vennerstrom, J.L.3
Roberts, D.4
Rogerson, S.5
Ginsburg, H.6
-
13
-
-
4944219983
-
Mechanism of in vitro hemeinduced LDL oxidation: effects of antioxidants
-
Klouche, K., Morena, M., Canaud, B., Descomps, B., Beraud, J.J., and Cristol, J.P. (2004) Mechanism of in vitro hemeinduced LDL oxidation: effects of antioxidants. Eur. J. Clin. Invest., 34, 619-625.
-
(2004)
Eur. J. Clin. Invest.
, vol.34
, pp. 619-625
-
-
Klouche, K.1
Morena, M.2
Canaud, B.3
Descomps, B.4
Beraud, J.J.5
Cristol, J.P.6
-
14
-
-
84907037304
-
Induction of oxidant stress by iron available in advanced forms of Plasmodium falciparum
-
Golenser, J., Marva, E., Har-El, R., and Chevion, M. (1991) Induction of oxidant stress by iron available in advanced forms of Plasmodium falciparum. Free Radic. Res. Commun., 12-13 (Pt 2), 639-643.
-
(1991)
Free Radic. Res. Commun.
, vol.12-13
, Issue.PT 2
, pp. 639-643
-
-
Golenser, J.1
Marva, E.2
Har-El, R.3
Chevion, M.4
-
15
-
-
38149035199
-
Haemozoin formation
-
Egan, T.J. (2008) Haemozoin formation. Mol. Biochem. Parasitol., 157, 127-136.
-
(2008)
Mol. Biochem. Parasitol.
, vol.157
, pp. 127-136
-
-
Egan, T.J.1
-
16
-
-
0031792787
-
Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action
-
Ginsburg, H., Famin, O., Zhang, J., and Krugliak, M. (1998) Inhibition of glutathione-dependent degradation of heme by chloroquine and amodiaquine as a possible basis for their antimalarial mode of action. Biochem. Pharmacol., 56, 1305-1313.
-
(1998)
Biochem. Pharmacol.
, vol.56
, pp. 1305-1313
-
-
Ginsburg, H.1
Famin, O.2
Zhang, J.3
Krugliak, M.4
-
17
-
-
33846455091
-
Antimalarial drugs inhibiting hemozoin (beta-hematin) formation: a mechanistic update
-
Kumar, S., Guha, M., Choubey, V., Maity, P., and Bandyopadhyay, U. (2007) Antimalarial drugs inhibiting hemozoin (beta-hematin) formation: a mechanistic update. Life Sci., 80, 813-828.
-
(2007)
Life Sci.
, vol.80
, pp. 813-828
-
-
Kumar, S.1
Guha, M.2
Choubey, V.3
Maity, P.4
Bandyopadhyay, U.5
-
18
-
-
0031847073
-
Quinoline antimalarials: mechanisms of action and resistance and prospects for new agents
-
Foley, M. and Tilley, L. (1998) Quinoline antimalarials: mechanisms of action and resistance and prospects for new agents. Pharmacol. Ther., 79, 55-87.
-
(1998)
Pharmacol. Ther.
, vol.79
, pp. 55-87
-
-
Foley, M.1
Tilley, L.2
-
19
-
-
0015496390
-
Lysosomes, pH and the anti-malarial action of chloroquine
-
Homewood, C.A., Warhurst, D.C., Peters, W., and Baggaley, V.C. (1972) Lysosomes, pH and the anti-malarial action of chloroquine. Nature, 235, 50-52.
-
(1972)
Nature
, vol.235
, pp. 50-52
-
-
Homewood, C.A.1
Warhurst, D.C.2
Peters, W.3
Baggaley, V.C.4
-
20
-
-
0024375736
-
Alkalinization of the food vacuole of malaria parasites by quinoline drugs and alkylamines is not correlated with their antimalarial activity
-
Ginsburg, H., Nissani, E., and Krugliak, M. (1989) Alkalinization of the food vacuole of malaria parasites by quinoline drugs and alkylamines is not correlated with their antimalarial activity. Biochem. Pharmacol., 38, 2645-2654.
-
(1989)
Biochem. Pharmacol.
, vol.38
, pp. 2645-2654
-
-
Ginsburg, H.1
Nissani, E.2
Krugliak, M.3
-
21
-
-
0016222658
-
High-affinity accumulation of chloroquine by mouse erythrocytes infected with Plasmodium berghei
-
Fitch, C.D., Yunis, N.G., Chevli, R., and Gonzalez, Y. (1974) High-affinity accumulation of chloroquine by mouse erythrocytes infected with Plasmodium berghei. J. Clin. Invest., 54, 24-33.
-
(1974)
J. Clin. Invest.
, vol.54
, pp. 24-33
-
-
Fitch, C.D.1
Yunis, N.G.2
Chevli, R.3
Gonzalez, Y.4
-
22
-
-
0030248458
-
Amodiaquine accumulation in Plasmodium falciparum as a possible explanation for its superior antimalarial activity over chloroquine
-
Hawley, S.R., Bray, P.G., Park, B.K., and Ward, S.A. (1996) Amodiaquine accumulation in Plasmodium falciparum as a possible explanation for its superior antimalarial activity over chloroquine. Mol. Biochem. Parasitol., 80, 15-25.
-
(1996)
Mol. Biochem. Parasitol.
, vol.80
, pp. 15-25
-
-
Hawley, S.R.1
Bray, P.G.2
Park, B.K.3
Ward, S.A.4
-
23
-
-
0022347074
-
Antimalarials increase vesicle pH in Plasmodium falciparum
-
Krogstad, D.J., Schlesinger, P.H., and Gluzman, I.Y. (1985) Antimalarials increase vesicle pH in Plasmodium falciparum. J. Cell Biol., 101, 2302-2309.
-
(1985)
J. Cell Biol.
, vol.101
, pp. 2302-2309
-
-
Krogstad, D.J.1
Schlesinger, P.H.2
Gluzman, I.Y.3
-
24
-
-
0023105195
-
The basis of antimalarial action: non-weak base effects of chloroquine on acid vesicle pH
-
Krogstad, D.J. and Schlesinger, P.H. (1987) The basis of antimalarial action: non-weak base effects of chloroquine on acid vesicle pH. Am. J. Trop. Med. Hyg., 36, 213-220.
-
(1987)
Am. J. Trop. Med. Hyg.
, vol.36
, pp. 213-220
-
-
Krogstad, D.J.1
Schlesinger, P.H.2
-
26
-
-
0039701257
-
+ exchanger determines chloroquine uptake in Plasmodium falciparum
-
+ exchanger determines chloroquine uptake in Plasmodium falciparum. J. Cell Biol., 140, 335-345.
-
(1998)
J. Cell Biol.
, vol.140
, pp. 335-345
-
-
Wunsch, S.1
Sanchez, C.P.2
Gekle, M.3
Grosse-Wortmann, L.4
Wiesner, J.5
Lanzer, M.6
-
27
-
-
0033584993
-
pH regulation in the intracellular malaria parasite, Plasmodium falciparum
-
Saliba, K.J. and Kirk, K. (1999) pH regulation in the intracellular malaria parasite, Plasmodium falciparum. H(+) extrusion via a v-type h(+)-atpase. J. Biol. Chem., 274, 33213-33219.
-
(1999)
H(+) extrusion via a v-type h(+)-atpase. J. Biol. Chem.
, vol.274
, pp. 33213-33219
-
-
Saliba, K.J.1
Kirk, K.2
-
28
-
-
0019188940
-
Ferriprotoporphyrin IX fulfills the criteria for identification as the chloroquine receptor of malaria parasites
-
Chou, A.C., Chevli, R., and Fitch, C.D. (1980) Ferriprotoporphyrin IX fulfills the criteria for identification as the chloroquine receptor of malaria parasites. Biochemistry, 19, 1543-1549.
-
(1980)
Biochemistry
, vol.19
, pp. 1543-1549
-
-
Chou, A.C.1
Chevli, R.2
Fitch, C.D.3
-
29
-
-
0344867895
-
Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity inPlasmodium falciparum
-
Bray, P.G., Janneh, O., Raynes, K.J., Mungthin, M., Ginsburg, H., and Ward, S.A. (1999) Cellular uptake of chloroquine is dependent on binding to ferriprotoporphyrin IX and is independent of NHE activity inPlasmodium falciparum. J. Cell Biol., 145, 363-376.
-
(1999)
J. Cell Biol.
, vol.145
, pp. 363-376
-
-
Bray, P.G.1
Janneh, O.2
Raynes, K.J.3
Mungthin, M.4
Ginsburg, H.5
Ward, S.A.6
-
30
-
-
0020214978
-
Interaction of chloroquine with ferriprotophorphyrin IX
-
Moreau, S., Perly, B., and Biguet, J. (1982) Interaction of chloroquine with ferriprotophorphyrin IX. Nuclear magnetic resonance study. Biochimie, 64, 1015-1025.
-
(1982)
Nuclear magnetic resonance study. Biochimie
, vol.64
, pp. 1015-1025
-
-
Moreau, S.1
Perly, B.2
Biguet, J.3
-
31
-
-
0029953812
-
The iron environment in heme and hemeantimalarial complexes of pharmacological interest
-
Adams, P.A., Berman, P.A., Egan, T.J., Marsh, P.J., and Silver, J. (1996) The iron environment in heme and hemeantimalarial complexes of pharmacological interest. J. Inorg. Biochem., 63, 69-77.
-
(1996)
J. Inorg. Biochem.
, vol.63
, pp. 69-77
-
-
Adams, P.A.1
Berman, P.A.2
Egan, T.J.3
Marsh, P.J.4
Silver, J.5
-
32
-
-
0030870923
-
Thermodynamic factors controlling the interaction of quinoline antimalarial drugs with ferriprotoporphyrin IX
-
Egan, T.J.,Mavuso,W.W., Ross, D.C., and Marques, H.M. (1997) Thermodynamic factors controlling the interaction of quinoline antimalarial drugs with ferriprotoporphyrin IX. J. Inorg. Biochem., 68, 137-145.
-
(1997)
J. Inorg. Biochem.
, vol.68
, pp. 137-145
-
-
Egan, T.J.1
Mavuso, W.W.2
Ross, D.C.3
Marques, H.M.4
-
33
-
-
0000884823
-
Complex formation between chloroquine and ferrihaemic acid in vitro, and its effect on the antimalarial action of chloroquine
-
Cohen, S.N., Phifer, K.O., and Yielding, K.L. (1964) Complex formation between chloroquine and ferrihaemic acid in vitro, and its effect on the antimalarial action of chloroquine. Nature, 202, 805-806.
-
(1964)
Nature
, vol.202
, pp. 805-806
-
-
Cohen, S.N.1
Phifer, K.O.2
Yielding, K.L.3
-
34
-
-
0037072289
-
Solution structures of antimalarial drug-heme complexes
-
Leed, A., DuBay, K., Ursos, L.M., Sears, D., De Dios, A.C., and Roepe, P.D. (2002) Solution structures of antimalarial drug-heme complexes. Biochemistry, 41, 10245-10255.
-
(2002)
Biochemistry
, vol.41
, pp. 10245-10255
-
-
Leed, A.1
DuBay, K.2
Ursos, L.M.3
Sears, D.4
De Dios, A.C.5
Roepe, P.D.6
-
35
-
-
67650066496
-
Aggregated enhanced Raman scattering in Fe(III)PPIX solutions: the effects of concentration and chloroquine on excitonic interactions
-
Webster, G.T., McNaughton, D., and Wood, B.R. (2009) Aggregated enhanced Raman scattering in Fe(III)PPIX solutions: the effects of concentration and chloroquine on excitonic interactions. J. Phys. Chem. B., 113, 6910-6916.
-
(2009)
J. Phys. Chem. B.
, vol.113
, pp. 6910-6916
-
-
Webster, G.T.1
McNaughton, D.2
Wood, B.R.3
-
36
-
-
0032520664
-
An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerisation by quinoline antimalarials
-
Dorn, A., Vippagunta, S.R., Matile, H., Jaquet, C., Vennerstrom, J.L., and Ridley, R.G. (1998) An assessment of drug-haematin binding as a mechanism for inhibition of haematin polymerisation by quinoline antimalarials. Biochem. Pharmacol., 55, 727-736.
-
(1998)
Biochem. Pharmacol.
, vol.55
, pp. 727-736
-
-
Dorn, A.1
Vippagunta, S.R.2
Matile, H.3
Jaquet, C.4
Vennerstrom, J.L.5
Ridley, R.G.6
-
37
-
-
0000615539
-
Antimalarial schizontocides: ferriprotoporphyrin IX interaction hypothesis
-
Fitch, C.D. (1986) Antimalarial schizontocides: ferriprotoporphyrin IX interaction hypothesis. Parasitol. Today, 2, 330-331.
-
(1986)
Parasitol. Today
, vol.2
, pp. 330-331
-
-
Fitch, C.D.1
-
38
-
-
0014004971
-
Chloroquine: physiological basis of drug resistance in Plasmodium berghei
-
Macomber, P.B., O'Brien, R.L., andHahn, F.E. (1966) Chloroquine: physiological basis of drug resistance in Plasmodium berghei. Science, 152, 1374-1375.
-
(1966)
Science
, vol.152
, pp. 1374-1375
-
-
Macomber, P.B.1
O'Brien, R.L.2
Hahn, F.E.3
-
39
-
-
0031041064
-
Depolymerization of malarial hemozoin: a novel reaction initiated by blood schizontocidal antimalarials
-
Pandey, A.V. and Tekwani, B.L. (1997) Depolymerization of malarial hemozoin: a novel reaction initiated by blood schizontocidal antimalarials. FEBS Lett., 402, 236-240.
-
(1997)
FEBS Lett.
, vol.402
, pp. 236-240
-
-
Pandey, A.V.1
Tekwani, B.L.2
-
41
-
-
0006552588
-
-
Springer-Verlag, Berlin, Heidelberg
-
Sweeney, T.R. (1984) Drugs with quininelike action, Antimalarial Drugs II: Current Antimalarials and New Drug Developments, Springer-Verlag, Berlin, Heidelberg, pp. 267-313.
-
(1984)
Drugs with quininelike action, Antimalarial Drugs II: Current Antimalarials and New Drug Developments
, pp. 267-313
-
-
Sweeney, T.R.1
-
42
-
-
0036681979
-
Structure-activity relationships in 4-aminoquinoline antiplasmodials
-
Kaschula, C.H., Egan, T.J., Hunter, R., Basilico, N., Parapini, S., Taramelli, D., Pasini, E. et al. (2002) Structure-activity relationships in 4-aminoquinoline antiplasmodials. The role of the group at the 7-position. J. Med. Chem., 45, 3531-3539.
-
(2002)
The role of the group at the 7-position. J. Med. Chem.
, vol.45
, pp. 3531-3539
-
-
Kaschula, C.H.1
Egan, T.J.2
Hunter, R.3
Basilico, N.4
Parapini, S.5
Taramelli, D.6
Pasini, E.7
-
43
-
-
0035352584
-
Structure-function relationships in chloroquine and related 4-aminoquinoline antimalarials
-
Egan, T.J. (2001) Structure-function relationships in chloroquine and related 4-aminoquinoline antimalarials. Mini Rev. Med. Chem., 1, 113-123.
-
(2001)
Mini Rev. Med. Chem.
, vol.1
, pp. 113-123
-
-
Egan, T.J.1
-
44
-
-
0032481004
-
Structure-activity relationships for antiplasmodial activity among 7-substituted 4-aminoquinolines
-
De, D., Krogstad, F.M., Byers, L.D., and Krogstad, D.J. (1998) Structure-activity relationships for antiplasmodial activity among 7-substituted 4-aminoquinolines. J. Med. Chem., 41, 4918-4926.
-
(1998)
J. Med. Chem.
, vol.41
, pp. 4918-4926
-
-
De, D.1
Krogstad, F.M.2
Byers, L.D.3
Krogstad, D.J.4
-
45
-
-
0031965067
-
4-Aminoquinolines-past, present, and future: a chemical perspective
-
O'Neill, P.M., Bray, P.G., Hawley, S.R., Ward, S.A., and Park, B.K. (1998) 4-Aminoquinolines-past, present, and future: a chemical perspective. Pharmacol. Ther., 77, 29-58.
-
(1998)
Pharmacol. Ther.
, vol.77
, pp. 29-58
-
-
O'Neill, P.M.1
Bray, P.G.2
Hawley, S.R.3
Ward, S.A.4
Park, B.K.5
-
46
-
-
0030483601
-
Aminoquinolines that circumvent resistance in Plasmodium falciparum in vitro
-
De, D., Krogstad, F.M., Cogswell, F.B., and Krogstad, D.J. (1996) Aminoquinolines that circumvent resistance in Plasmodium falciparum in vitro. Am. J. Trop. Med. Hyg., 55, 579-583.
-
(1996)
Am. J. Trop. Med. Hyg.
, vol.55
, pp. 579-583
-
-
De, D.1
Krogstad, F.M.2
Cogswell, F.B.3
Krogstad, D.J.4
-
47
-
-
9444258557
-
4-aminoquinoline analogs of chloroquine with shortened side chains retain activity against chloroquine-resistant Plasmodium falciparum
-
Ridley, R.G., Hofheinz, W., Matile, H., Jaquet, C., Dorn, A., Masciadri, R., Jolidon, S. et al. (1996) 4-aminoquinoline analogs of chloroquine with shortened side chains retain activity against chloroquine-resistant Plasmodium falciparum. Antimicrob. Agents Chemother., 40, 1846-1854.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 1846-1854
-
-
Ridley, R.G.1
Hofheinz, W.2
Matile, H.3
Jaquet, C.4
Dorn, A.5
Masciadri, R.6
Jolidon, S.7
-
49
-
-
0022006971
-
Amodiaquine as a prodrug: importance of metabolite(s) in the antimalarial effect of amodiaquine in humans
-
Churchill, F.C., Patchen, L.C., Campbell, C.C., Schwartz, I.K., Nguyen-Dinh, P., and Dickinson, C.M. (1985) Amodiaquine as a prodrug: importance of metabolite(s) in the antimalarial effect of amodiaquine in humans. Life Sci., 36, 53-62.
-
(1985)
Life Sci.
, vol.36
, pp. 53-62
-
-
Churchill, F.C.1
Patchen, L.C.2
Campbell, C.C.3
Schwartz, I.K.4
Nguyen-Dinh, P.5
Dickinson, C.M.6
-
50
-
-
0027096883
-
The chemotherapy of rodent malaria. XLVII. Studies on pyronaridine and other Mannich base antimalarials
-
Peters,W. and Robinson, B.L. (1992) The chemotherapy of rodent malaria. XLVII. Studies on pyronaridine and other Mannich base antimalarials. Ann. Trop. Med. Parasitol., 86, 455-465.
-
(1992)
Ann. Trop. Med. Parasitol.
, vol.86
, pp. 455-465
-
-
Peters, W.1
Robinson, B.L.2
-
51
-
-
0029817144
-
Manipulation of the N-alkyl substituent in amodiaquine to overcome the verapamil-sensitive chloroquine resistance component
-
Hawley, S.R., Bray, P.G., O'Neill, P.M., Naisbitt, D.J., Park, B.K., and Ward, S.A. (1996) Manipulation of the N-alkyl substituent in amodiaquine to overcome the verapamil-sensitive chloroquine resistance component. Antimicrob. Agents Chemother., 40, 2345-2349.
-
(1996)
Antimicrob. Agents Chemother.
, vol.40
, pp. 2345-2349
-
-
Hawley, S.R.1
Bray, P.G.2
O'Neill, P.M.3
Naisbitt, D.J.4
Park, B.K.5
Ward, S.A.6
-
52
-
-
0031055744
-
Synthesis, antimalarial activity, and molecular modeling of tebuquine analogues
-
O'Neill, P.M., Willock, D.J.,Hawley, S.R., Bray, P.G., Storr, R.C., Ward, S.A., and Park, B.K. (1997) Synthesis, antimalarial activity, and molecular modeling of tebuquine analogues. J. Med. Chem., 40, 437-448.
-
(1997)
J. Med. Chem.
, vol.40
, pp. 437-448
-
-
O'Neill, P.M.1
Willock, D.J.2
Hawley, S.R.3
Bray, P.G.4
Storr, R.C.5
Ward, S.A.6
Park, B.K.7
-
53
-
-
0030451452
-
Physicochemical properties correlated with drug resistance and the reversal of drug resistance in Plasmodium falciparum
-
Bray, P.G., Hawley, S.R., Mungthin, M., and Ward, S.A. (1996) Physicochemical properties correlated with drug resistance and the reversal of drug resistance in Plasmodium falciparum. Mol. Pharmacol., 50, 1559-1566.
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 1559-1566
-
-
Bray, P.G.1
Hawley, S.R.2
Mungthin, M.3
Ward, S.A.4
-
54
-
-
0022655075
-
Amodiaquine induced agranulocytosis and liver damage
-
Neftel, K.A., Woodtly, W., Schmid, M., Frick, P.G., and Fehr, J. (1986) Amodiaquine induced agranulocytosis and liver damage. Br. Med. J. (Clin. Res. Ed.): 292, 721-723.
-
(1986)
Br. Med. J. (Clin. Res. Ed.):
, vol.292
, pp. 721-723
-
-
Neftel, K.A.1
Woodtly, W.2
Schmid, M.3
Frick, P.G.4
Fehr, J.5
-
55
-
-
0242267910
-
Isoquine and related amodiaquine analogues: a new generation of improved 4-aminoquinoline antimalarials
-
O'Neill, P.M., Mukhtar, A., Stocks, P.A., Randle, L.E., Hindley, S., Ward, S.A., Storr, R.C. et al. (2003) Isoquine and related amodiaquine analogues: a new generation of improved 4-aminoquinoline antimalarials. J. Med. Chem., 46, 4933-4945.
-
(2003)
J. Med. Chem.
, vol.46
, pp. 4933-4945
-
-
O'Neill, P.M.1
Mukhtar, A.2
Stocks, P.A.3
Randle, L.E.4
Hindley, S.5
Ward, S.A.6
Storr, R.C.7
-
56
-
-
65549102629
-
Replacement of the 40- hydroxy group of amodiaquine and amopyroquine by aromatic and aliphatic substituents: synthesis and antimalarial activity
-
Paunescu, E., Susplugas, S., Boll, E., Varga, R., Mouray, E., Grosu, I., Grellier, P. et al. (2009) Replacement of the 40- hydroxy group of amodiaquine and amopyroquine by aromatic and aliphatic substituents: synthesis and antimalarial activity. ChemMedChem, 4, 549-561.
-
(2009)
ChemMedChem
, vol.4
, pp. 549-561
-
-
Paunescu, E.1
Susplugas, S.2
Boll, E.3
Varga, R.4
Mouray, E.5
Grosu, I.6
Grellier, P.7
-
57
-
-
0026541268
-
Studies on a new antimalarial compound: pyronaridine
-
Chang, C., Lin-Hua, T., and Jantanavivat, C. (1992) Studies on a new antimalarial compound: pyronaridine. Trans. R. Soc. Trop. Med. Hyg., 86, 7-10.
-
(1992)
Trans. R. Soc. Trop. Med. Hyg.
, vol.86
, pp. 7-10
-
-
Chang, C.1
Lin-Hua, T.2
Jantanavivat, C.3
-
58
-
-
0026095986
-
Pyronaridine: A new antimalarial drug
-
Fu, S. and Xiao, S.H. (1991) Pyronaridine: A new antimalarial drug. Parasitol. Today, 7, 310-313.
-
(1991)
Parasitol. Today
, vol.7
, pp. 310-313
-
-
Fu, S.1
Xiao, S.H.2
-
59
-
-
0030969247
-
New quinoline di-Mannich base compounds with greater antimalarial activity than chloroquine, amodiaquine, or pyronaridine
-
Kotecka, B.M., Barlin, G.B., Edstein, M.D., and Rieckmann, K.H. (1997) New quinoline di-Mannich base compounds with greater antimalarial activity than chloroquine, amodiaquine, or pyronaridine. Antimicrob. Agents Chemother., 41, 1369-1374.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1369-1374
-
-
Kotecka, B.M.1
Barlin, G.B.2
Edstein, M.D.3
Rieckmann, K.H.4
-
60
-
-
0034719487
-
Structure-function relationships in aminoquinolines: effect of amino and chloro groups on quinolinehematin complex formation, inhibition of beta-hematin formation, and antiplasmodial activity
-
Egan, T.J., Hunter, R., Kaschula, C.H., Marques, H.M., Misplon, A., and Walden, J. (2000) Structure-function relationships in aminoquinolines: effect of amino and chloro groups on quinolinehematin complex formation, inhibition of beta-hematin formation, and antiplasmodial activity. J.Med. Chem., 43, 283-291.
-
(2000)
J.Med. Chem.
, vol.43
, pp. 283-291
-
-
Egan, T.J.1
Hunter, R.2
Kaschula, C.H.3
Marques, H.M.4
Misplon, A.5
Walden, J.6
-
61
-
-
84884082679
-
-
Springer-Verlag, Berlin, Heidelberg
-
McChesney, E.W. and Fitch, C.D. (1984) 4-Aminoquinolines, in Antimalarial Drugs II: Current Antimalarials and New Drug Developments (eds W. Peters and W.H.G. Richards), Springer-Verlag, Berlin, Heidelberg, pp. 30-60.
-
(1984)
4-Aminoquinolines, in Antimalarial Drugs II: Current Antimalarials and New Drug Developments (eds W. Peters and W.H.G. Richards)
, pp. 30-60
-
-
McChesney, E.W.1
Fitch, C.D.2
-
62
-
-
0026095736
-
Crystal structure and molecular structure of mefloquine methylsulfonate monohydrate: implications for a malaria receptor
-
Karle, J.M. and Karle, I.L. (1991) Crystal structure and molecular structure of mefloquine methylsulfonate monohydrate: implications for a malaria receptor. Antimicrob. Agents Chemother., 35, 2238-2245.
-
(1991)
Antimicrob. Agents Chemother.
, vol.35
, pp. 2238-2245
-
-
Karle, J.M.1
Karle, I.L.2
-
63
-
-
0027254271
-
Neuropsychiatric side effects of mefloquine in Africans
-
Sowunmi, A., Salako, L.A., Oduola, A.M., Walker, O., Akindele, J.A., and Ogundahunsi, O.A. (1993) Neuropsychiatric side effects of mefloquine in Africans. Trans. R. Soc. Trop. Med. Hyg., 87, 462-463.
-
(1993)
Trans. R. Soc. Trop. Med. Hyg.
, vol.87
, pp. 462-463
-
-
Sowunmi, A.1
Salako, L.A.2
Oduola, A.M.3
Walker, O.4
Akindele, J.A.5
Ogundahunsi, O.A.6
-
64
-
-
75149172729
-
Fatal cardiotoxicity related to halofantrine: a review based on a worldwide safety data base
-
Bouchaud, O., Imbert, P., Touze, J.E., Dodoo, A.N., Danis, M., and Legros, F. (2009) Fatal cardiotoxicity related to halofantrine: a review based on a worldwide safety data base. Malar. J., 8, 289.
-
(2009)
Malar. J.
, vol.8
, pp. 289
-
-
Bouchaud, O.1
Imbert, P.2
Touze, J.E.3
Dodoo, A.N.4
Danis, M.5
Legros, F.6
-
65
-
-
0033386669
-
No evidence of cardiotoxicity during antimalarial treatment with artemetherlumefantrine
-
van Vugt, M., Ezzet, F., Nosten, F., Gathmann, I., Wilairatana, P., Looareesuwan, S., and White, N.J. (1999) No evidence of cardiotoxicity during antimalarial treatment with artemetherlumefantrine. Am. J. Trop. Med. Hyg., 61, 964-967.
-
(1999)
Am. J. Trop. Med. Hyg.
, vol.61
, pp. 964-967
-
-
van Vugt, M.1
Ezzet, F.2
Nosten, F.3
Gathmann, I.4
Wilairatana, P.5
Looareesuwan, S.6
White, N.J.7
-
66
-
-
44749091704
-
Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline
-
Sparatore, A., Basilico, N., Casagrande, M., Parapini, S., Taramelli, D., Brun, R., Wittlin, S. et al. (2008) Antimalarial activity of novel pyrrolizidinyl derivatives of 4-aminoquinoline. Bioorg. Med. Chem. Lett., 18, 3737-3740.
-
(2008)
Bioorg. Med. Chem. Lett.
, vol.18
, pp. 3737-3740
-
-
Sparatore, A.1
Basilico, N.2
Casagrande, M.3
Parapini, S.4
Taramelli, D.5
Brun, R.6
Wittlin, S.7
-
67
-
-
64349106120
-
Synthesis of novel thiourea, thiazolidinedione and thioparabanic acid derivatives of 4-aminoquinoline as potent antimalarials
-
Sunduru, N., Srivastava, K., Rajakumar, S., Puri, S.K., Saxena, J.K., and Chauhan, P.M. (2009) Synthesis of novel thiourea, thiazolidinedione and thioparabanic acid derivatives of 4-aminoquinoline as potent antimalarials. Bioorg. Med. Chem. Lett., 19, 2570-2573.
-
(2009)
Bioorg. Med. Chem. Lett.
, vol.19
, pp. 2570-2573
-
-
Sunduru, N.1
Srivastava, K.2
Rajakumar, S.3
Puri, S.K.4
Saxena, J.K.5
Chauhan, P.M.6
-
68
-
-
64249139717
-
Synthesis and antileishmanial activity of novel 2,4,6- trisubstituted pyrimidines and 1,3,5- triazines
-
Sunduru, N., Nishi, Palne, S., Chauhan, P.M., and Gupta, S. (2009) Synthesis and antileishmanial activity of novel 2,4,6- trisubstituted pyrimidines and 1,3,5- triazines. Eur. J. Med. Chem., 44, 2473-2481.
-
(2009)
Eur. J. Med. Chem.
, vol.44
, pp. 2473-2481
-
-
Sunduru, N.1
Nishi Palne, S.2
Chauhan, P.M.3
Gupta, S.4
-
69
-
-
0019827259
-
Hydroxypiperaquine phosphate in treatment of falciparum malaria
-
Li, Y.T., Hu, Y.G., Huang, H.Z., Zhu, D.Q., Huang, W.J., Wu, D.L., and Qian, Y.L. (1981) Hydroxypiperaquine phosphate in treatment of falciparum malaria. Chin. Med. J. (Engl.), 94, 301-302.
-
(1981)
Chin. Med. J. (Engl.)
, vol.94
, pp. 301-302
-
-
Li, Y.T.1
Hu, Y.G.2
Huang, H.Z.3
Zhu, D.Q.4
Huang, W.J.5
Wu, D.L.6
Qian, Y.L.7
-
70
-
-
0026762480
-
Bisquinolines. 1.N, N-bis(7-chloroquinolin-4-yl) alkanediamines with potential against chloroquine-resistant malaria
-
Vennerstrom, J.L., Ellis, W.Y., Ager, A.L. Jr, Andersen, S.L., Gerena, L., and Milhous,W.K. (1992) Bisquinolines. 1.N, N-bis(7-chloroquinolin-4-yl) alkanediamines with potential against chloroquine-resistant malaria. J. Med. Chem., 35, 2129-2134.
-
(1992)
J. Med. Chem.
, vol.35
, pp. 2129-2134
-
-
Vennerstrom, J.L.1
Ellis, W.Y.2
Ager Jr., A.L.3
Andersen, S.L.4
Gerena, L.5
Milhous, W.K.6
-
71
-
-
0032959813
-
Bisquinoline antimalarials: their role in malaria chemotherapy
-
Raynes, K. (1999) Bisquinoline antimalarials: their role in malaria chemotherapy. Int. J. Parasitol., 29, 367-379.
-
(1999)
Int. J. Parasitol.
, vol.29
, pp. 367-379
-
-
Raynes, K.1
-
72
-
-
0020673925
-
Dichlorquinazine (alpha 4-aminoquinoline) effective in vitro against chloroquine-resistant Plasmodium falciparum
-
Le Bras, J., Deloron, P., and Charmot, G. (1983) Dichlorquinazine (alpha 4-aminoquinoline) effective in vitro against chloroquine-resistant Plasmodium falciparum. Lancet, 1, 73-74.
-
(1983)
Lancet
, vol.1
, pp. 73-74
-
-
Le Bras, J.1
Deloron, P.2
Charmot, G.3
-
73
-
-
0026100093
-
Recent studies on antimalarial efficacy of piperaquine and hydroxypiperaquine
-
Chen, L. (1991) Recent studies on antimalarial efficacy of piperaquine and hydroxypiperaquine. Chin. Med. J. (Engl.), 104, 161-163.
-
(1991)
Chin. Med. J. (Engl.)
, vol.104
, pp. 161-163
-
-
Chen, L.1
-
74
-
-
12444319401
-
Piperaquine: a resurgent antimalarial drug
-
Davis, T.M., Hung, T.Y., Sim, I.K., Karunajeewa, H.A., and Ilett, K.F. (2005) Piperaquine: a resurgent antimalarial drug. Drugs, 65, 75-87.
-
(2005)
Drugs
, vol.65
, pp. 75-87
-
-
Davis, T.M.1
Hung, T.Y.2
Sim, I.K.3
Karunajeewa, H.A.4
Ilett, K.F.5
-
75
-
-
0031018611
-
Antimalarial activity of the bisquinoline trans-N1,N2-bis (7- chloroquinolin-4-yl)cyclohexane-1,2- diamine: comparison of two stereoisomers and detailed evaluation of the S,S enantiomer, Ro 47-7737
-
Ridley, R.G.,Matile, H., Jaquet, C., Dorn, A., Hofheinz, W., Leupin, W., Masciadri, R. et al. (1997) Antimalarial activity of the bisquinoline trans-N1,N2-bis (7- chloroquinolin-4-yl)cyclohexane-1,2- diamine: comparison of two stereoisomers and detailed evaluation of the S,S enantiomer, Ro 47-7737. Antimicrob. Agents Chemother., 41, 677-686.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 677-686
-
-
Ridley, R.G.1
Matile, H.2
Jaquet, C.3
Dorn, A.4
Hofheinz, W.5
Leupin, W.6
Masciadri, R.7
-
76
-
-
0029957025
-
Novel bisquinoline antimalarials
-
Biochem. Pharmacol.
-
Raynes, K., Foley, M., Tilley, L., and Deady, L.W. (1996) Novel bisquinoline antimalarials. Synthesis, antimalarial activity, and inhibition of haem polymerisation. Biochem. Pharmacol., 52, 551-559.
-
(1996)
Synthesis, antimalarial activity, and inhibition of haem polymerisation
, vol.52
, pp. 551-559
-
-
Raynes, K.1
Foley, M.2
Tilley, L.3
Deady, L.W.4
-
77
-
-
0030878175
-
Potentiation of an antimalarial oxidant drug
-
Winter, R.W., Ignatushchenko, M., Ogundahunsi, O.A., Cornell, K.A., Oduola, A.M.,Hinrichs, D.J., and Riscoe, M.K. (1997) Potentiation of an antimalarial oxidant drug. Antimicrob. Agents Chemother., 41, 1449-1454.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 1449-1454
-
-
Winter, R.W.1
Ignatushchenko, M.2
Ogundahunsi, O.A.3
Cornell, K.A.4
Oduola, A.M.5
Hinrichs, D.J.6
Riscoe, M.K.7
-
78
-
-
0030961389
-
Xanthones as antimalarial agents; studies of a possible mode of action
-
Ignatushchenko, M.V., Winter, R.W., Bachinger, H.P., Hinrichs, D.J., and Riscoe, M.K. (1997) Xanthones as antimalarial agents; studies of a possible mode of action. FEBS Lett., 409, 67-73.
-
(1997)
FEBS Lett.
, vol.409
, pp. 67-73
-
-
Ignatushchenko, M.V.1
Winter, R.W.2
Bachinger, H.P.3
Hinrichs, D.J.4
Riscoe, M.K.5
-
79
-
-
0034836969
-
A spectroscopic investigation of the binding interactions between 4,5-dihydroxyxanthone and heme
-
Xu Kelly, J., Winter, R., Riscoe, M., and Peyton, D.H. (2001) A spectroscopic investigation of the binding interactions between 4,5-dihydroxyxanthone and heme. J. Inorg. Biochem., 86, 617-625.
-
(2001)
J. Inorg. Biochem.
, vol.86
, pp. 617-625
-
-
Xu Kelly, J.1
Winter, R.2
Riscoe, M.3
Peyton, D.H.4
-
80
-
-
0344984312
-
In-vivo antimalarial activity of some oxygenated xanthones
-
Fotie, J., Nkengfack, A.E., Rukunga, G., Tolo, F., Peter, M.G., Heydenreich, M., and Fomum, Z.T. (2003) In-vivo antimalarial activity of some oxygenated xanthones. Ann. Trop. Med. Parasitol., 97, 683-688.
-
(2003)
Ann. Trop. Med. Parasitol.
, vol.97
, pp. 683-688
-
-
Fotie, J.1
Nkengfack, A.E.2
Rukunga, G.3
Tolo, F.4
Peter, M.G.5
Heydenreich, M.6
Fomum, Z.T.7
-
81
-
-
0034026087
-
Xanthones as antimalarial agents: stage specificity
-
Ignatushchenko, M.V., Winter, R.W., and Riscoe, M. (2000) Xanthones as antimalarial agents: stage specificity. Am. J. Trop. Med. Hyg., 62, 77-81.
-
(2000)
Am. J. Trop. Med. Hyg.
, vol.62
, pp. 77-81
-
-
Ignatushchenko, M.V.1
Winter, R.W.2
Riscoe, M.3
-
82
-
-
4944253976
-
Antimalarial xanthones from Calophyllum caledonicum and Garcinia vieillardii
-
Hay, A.E., Helesbeux, J.J., Duval, O., Labaied, M., Grellier, P., and Richomme, P. (2004) Antimalarial xanthones from Calophyllum caledonicum and Garcinia vieillardii. Life Sci., 75, 3077-3085.
-
(2004)
Life Sci.
, vol.75
, pp. 3077-3085
-
-
Hay, A.E.1
Helesbeux, J.J.2
Duval, O.3
Labaied, M.4
Grellier, P.5
Richomme, P.6
-
83
-
-
0036135320
-
Optimization of xanthones for antimalarial activity: the 3,6-bis-omegadiethylaminoalkoxyxanthone series
-
Kelly, J.X., Winter, R., Peyton, D.H., Hinrichs, D.J., and Riscoe, M. (2002) Optimization of xanthones for antimalarial activity: the 3,6-bis-omegadiethylaminoalkoxyxanthone series. Antimicrob. Agents Chemother., 46, 144-150.
-
(2002)
Antimicrob. Agents Chemother.
, vol.46
, pp. 144-150
-
-
Kelly, J.X.1
Winter, R.2
Peyton, D.H.3
Hinrichs, D.J.4
Riscoe, M.5
-
84
-
-
0027104896
-
Antimalarial activity of sesquiterpenes from the marine sponge Acanthella klethra
-
Angerhofer, C.K., Pezzuto, J.M., Konig, G.M., Wright, A.D., and Sticher, O. (1992) Antimalarial activity of sesquiterpenes from the marine sponge Acanthella klethra. J. Nat. Prod., 55, 1787-1789.
-
(1992)
J. Nat. Prod.
, vol.55
, pp. 1787-1789
-
-
Angerhofer, C.K.1
Pezzuto, J.M.2
Konig, G.M.3
Wright, A.D.4
Sticher, O.5
-
85
-
-
0035866625
-
Inhibition of heme detoxification processes underlies the antimalarial activity of terpene isonitrile compounds from marine sponges
-
Wright, A.D., Wang, H., Gurrath, M., Konig, G.M., Kocak, G., Neumann, G., Loria, P. et al. (2001) Inhibition of heme detoxification processes underlies the antimalarial activity of terpene isonitrile compounds from marine sponges. J. Med. Chem., 44, 873-885.
-
(2001)
J. Med. Chem.
, vol.44
, pp. 873-885
-
-
Wright, A.D.1
Wang, H.2
Gurrath, M.3
Konig, G.M.4
Kocak, G.5
Neumann, G.6
Loria, P.7
-
86
-
-
0037016960
-
Synthesis and biological evaluation of new antimalarial isonitriles related to marine diterpenoids
-
Schwarz, O., Brun, R., Bats, J.W., and Schmalz, H.-G. (2002) Synthesis and biological evaluation of new antimalarial isonitriles related to marine diterpenoids. Tetrahedron Lett., 43, 1009-1013.
-
(2002)
Tetrahedron Lett.
, vol.43
, pp. 1009-1013
-
-
Schwarz, O.1
Brun, R.2
Bats, J.W.3
Schmalz, H.-G.4
-
87
-
-
0037009290
-
In vivo active antimalarial isonitriles
-
Singh, C., Srivastav, N.C., and Puri, S.K. (2002) In vivo active antimalarial isonitriles. Bioorg. Med. Chem. Lett., 12, 2277-2279.
-
(2002)
Bioorg. Med. Chem. Lett.
, vol.12
, pp. 2277-2279
-
-
Singh, C.1
Srivastav, N.C.2
Puri, S.K.3
-
88
-
-
2342468596
-
Total synthesis of (+/-)-kalihinol C
-
White, R.D., Keaney, G.F., Slown, C.D., and Wood, J.L. (2004) Total synthesis of (+/-)-kalihinol C. Org. Lett., 6, 1123-1126.
-
(2004)
Org. Lett.
, vol.6
, pp. 1123-1126
-
-
White, R.D.1
Keaney, G.F.2
Slown, C.D.3
Wood, J.L.4
-
89
-
-
0027537795
-
Structure-activity relationships and modes of action of 9-anilinoacridines against chloroquineresistant Plasmodium falciparum in vitro
-
Chavalitshewinkoon, P., Wilairat, P., Gamage, S., Denny, W., Figgitt, D., and Ralph, R. (1993) Structure-activity relationships and modes of action of 9-anilinoacridines against chloroquineresistant Plasmodium falciparum in vitro. Antimicrob. Agents Chemother., 37, 403-406.
-
(1993)
Antimicrob. Agents Chemother.
, vol.37
, pp. 403-406
-
-
Chavalitshewinkoon, P.1
Wilairat, P.2
Gamage, S.3
Denny, W.4
Figgitt, D.5
Ralph, R.6
-
90
-
-
4444252126
-
Arylsulfonyl acridinyl derivatives acting on Plasmodium falciparum
-
Santelli-Rouvier, C., Pradines, B., Berthelot, M., Parzy, D., and Barbe, J. (2004) Arylsulfonyl acridinyl derivatives acting on Plasmodium falciparum. Eur. J. Med. Chem., 39, 735-744.
-
(2004)
Eur. J. Med. Chem.
, vol.39
, pp. 735-744
-
-
Santelli-Rouvier, C.1
Pradines, B.2
Berthelot, M.3
Parzy, D.4
Barbe, J.5
-
91
-
-
0034673530
-
Cleavage of DNA induced by 9- anilinoacridine inhibitors of topoisomerase II in the malaria parasite Plasmodium falciparum
-
Auparakkitanon, S. and Wilairat, P. (2000) Cleavage of DNA induced by 9- anilinoacridine inhibitors of topoisomerase II in the malaria parasite Plasmodium falciparum. Biochem. Biophys. Res. Commun., 269, 406-409.
-
(2000)
Biochem. Biophys. Res. Commun.
, vol.269
, pp. 406-409
-
-
Auparakkitanon, S.1
Wilairat, P.2
-
92
-
-
0031328626
-
Inhibition of mammalian topoisomerase I by 1-nitro-9- aminoacridines
-
Ciesielska, E., Pastwa, E., and Szmigiero, L. (1997) Inhibition of mammalian topoisomerase I by 1-nitro-9- aminoacridines. Dependence on thiol activation.Acta Biochim. Pol., 44, 775-780.
-
(1997)
Dependence on thiol activation.Acta Biochim. Pol.
, vol.44
, pp. 775-780
-
-
Ciesielska, E.1
Pastwa, E.2
Szmigiero, L.3
-
93
-
-
0035830368
-
The mechanism of betahematin formation in acetate solution
-
Egan, T.J., Mavuso, W.W., and Ncokazi, K.K. (2001) The mechanism of betahematin formation in acetate solution. Parallels between hemozoin formation and biomineralization processes. Biochemistry, 40, 204-213.
-
(2001)
Parallels between hemozoin formation and biomineralization processes. Biochemistry
, vol.40
, pp. 204-213
-
-
Egan, T.J.1
Mavuso, W.W.2
Ncokazi, K.K.3
-
94
-
-
0345306193
-
Antimalarial 9-anilinoacridine compounds directed at hematin
-
Auparakkitanon, S., Noonpakdee, W., Ralph, R.K., Denny,W.A., and Wilairat, P. (2003) Antimalarial 9-anilinoacridine compounds directed at hematin. Antimicrob. Agents Chemother., 47, 3708-3712.
-
(2003)
Antimicrob. Agents Chemother.
, vol.47
, pp. 3708-3712
-
-
Auparakkitanon, S.1
Noonpakdee, W.2
Ralph, R.K.3
Denny, W.A.4
Wilairat, P.5
-
95
-
-
0028360131
-
Synthesis and in vitro evaluation of 9-anilino-3,6- diaminoacridines active against a multidrug-resistant strain of the malaria parasite Plasmodium falciparum
-
Gamage, S.A., Tepsiri, N., Wilairat, P., Wojcik, S.J., Figgitt, D.P., Ralph, R.K., and Denny, W.A. (1994) Synthesis and in vitro evaluation of 9-anilino-3,6- diaminoacridines active against a multidrug-resistant strain of the malaria parasite Plasmodium falciparum. J. Med. Chem., 37, 1486-1494.
-
(1994)
J. Med. Chem.
, vol.37
, pp. 1486-1494
-
-
Gamage, S.A.1
Tepsiri, N.2
Wilairat, P.3
Wojcik, S.J.4
Figgitt, D.P.5
Ralph, R.K.6
Denny, W.A.7
-
96
-
-
72149093269
-
Antimalarial acridines: synthesis, in vitro activity against P
-
Guetzoyan, L., Yu, X.M., Ramiandrasoa, F., Pethe, S., Rogier, C., Pradines, B., Cresteil, T. et al. (2009) Antimalarial acridines: synthesis, in vitro activity against P. falciparum and interaction with hematin. Bioorg. Med. Chem., 17, 8032-8039.
-
(2009)
falciparum and interaction with hematin. Bioorg. Med. Chem.
, vol.17
, pp. 8032-8039
-
-
Guetzoyan, L.1
Yu, X.M.2
Ramiandrasoa, F.3
Pethe, S.4
Rogier, C.5
Pradines, B.6
Cresteil, T.7
-
97
-
-
67349189204
-
Discovery of dual function acridones as a new antimalarial chemotype
-
Kelly, J.X., Smilkstein, M.J., Brun, R., Wittlin, S., Cooper, R.A., Lane, K.D., Janowsky, A. et al. (2009) Discovery of dual function acridones as a new antimalarial chemotype. Nature, 459, 270-273.
-
(2009)
Nature
, vol.459
, pp. 270-273
-
-
Kelly, J.X.1
Smilkstein, M.J.2
Brun, R.3
Wittlin, S.4
Cooper, R.A.5
Lane, K.D.6
Janowsky, A.7
-
98
-
-
0242408771
-
Inhibition of heme crystal growth by antimalarials and other compounds: implications for drug discovery
-
Chong, C.R. and Sullivan, D.J. Jr (2003) Inhibition of heme crystal growth by antimalarials and other compounds: implications for drug discovery. Biochem. Pharmacol., 66, 2201-2212.
-
(2003)
Biochem. Pharmacol.
, vol.66
, pp. 2201-2212
-
-
Chong, C.R.1
Sullivan, D.J.2
-
99
-
-
0037040221
-
Clotrimazole binds to heme and enhances hemedependent hemolysis: proposed antimalarial mechanism of clotrimazole
-
Huy, N.T., Kamei, K., Yamamoto, T., Kondo, Y., Kanaori, K., Takano, R., Tajima, K. et al. (2002) Clotrimazole binds to heme and enhances hemedependent hemolysis: proposed antimalarial mechanism of clotrimazole. J. Biol. Chem., 277, 4152-4158.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 4152-4158
-
-
Huy, N.T.1
Kamei, K.2
Yamamoto, T.3
Kondo, Y.4
Kanaori, K.5
Takano, R.6
Tajima, K.7
-
100
-
-
0036220122
-
Effect of antifungal azoles on the heme detoxification system of malarial parasite
-
Huy, N.T., Kamei, K., Kondo, Y., Serada, S., Kanaori, K., Takano, R., Tajima, K. et al. (2002) Effect of antifungal azoles on the heme detoxification system of malarial parasite. J. Biochem., 131, 437-444.
-
(2002)
J. Biochem.
, vol.131
, pp. 437-444
-
-
Huy, N.T.1
Kamei, K.2
Kondo, Y.3
Serada, S.4
Kanaori, K.5
Takano, R.6
Tajima, K.7
-
101
-
-
24644438428
-
Clotrimazole inhibits hemoperoxidase of Plasmodiumfalciparum and induces oxidative stress
-
Trivedi, V., Chand, P., Srivastava, K., Puri, S.K., Maulik, P.R., and Bandyopadhyay, U. (2005) Clotrimazole inhibits hemoperoxidase of Plasmodiumfalciparum and induces oxidative stress. Proposed antimalarial mechanism of clotrimazole. J. Biol. Chem., 280, 41129-41136.
-
(2005)
Proposed antimalarial mechanism of clotrimazole. J. Biol. Chem.
, vol.280
, pp. 41129-41136
-
-
Trivedi, V.1
Chand, P.2
Srivastava, K.3
Puri, S.K.4
Maulik, P.R.5
Bandyopadhyay, U.6
-
102
-
-
33847400024
-
Design and synthesis of potent antimalarial agents based on clotrimazole scaffold: exploring an innovative pharmacophore
-
Gemma, S., Campiani, G., Butini, S., Kukreja, G., Joshi, B.P., Persico, M., Catalanotti, B. et al. (2007) Design and synthesis of potent antimalarial agents based on clotrimazole scaffold: exploring an innovative pharmacophore. J. Med. Chem., 50, 595-598.
-
(2007)
J. Med. Chem.
, vol.50
, pp. 595-598
-
-
Gemma, S.1
Campiani, G.2
Butini, S.3
Kukreja, G.4
Joshi, B.P.5
Persico, M.6
Catalanotti, B.7
-
103
-
-
41649106230
-
Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure-activity relationship studies
-
Gemma, S., Campiani, G., Butini, S., Kukreja, G., Coccone, S.S., Joshi, B.P., Persico, M. et al. (2008) Clotrimazole scaffold as an innovative pharmacophore towards potent antimalarial agents: design, synthesis, and biological and structure-activity relationship studies. J. Med. Chem., 51, 1278-1294.
-
(2008)
J. Med. Chem.
, vol.51
, pp. 1278-1294
-
-
Gemma, S.1
Campiani, G.2
Butini, S.3
Kukreja, G.4
Coccone, S.S.5
Joshi, B.P.6
Persico, M.7
-
104
-
-
0029987752
-
Mode of antimalarial effect of methylene blue and some of its analogues on Plasmodium falciparum in culture and their inhibition of P. vinckei petteri and P. yoelii nigeriensis in vivo
-
Atamna, H., Krugliak, M., Shalmiev, G., Deharo, E., Pescarmona, G., and Ginsburg, H. (1996) Mode of antimalarial effect of methylene blue and some of its analogues on Plasmodium falciparum in culture and their inhibition of P. vinckei petteri and P. yoelii nigeriensis in vivo. Biochem. Pharmacol., 51, 693-700.
-
(1996)
Biochem. Pharmacol.
, vol.51
, pp. 693-700
-
-
Atamna, H.1
Krugliak, M.2
Shalmiev, G.3
Deharo, E.4
Pescarmona, G.5
Ginsburg, H.6
-
105
-
-
0028800123
-
Antimalarial dyes revisited: xanthenes, azines, oxazines, and thiazines
-
Vennerstrom, J.L., Makler, M.T., Angerhofer, C.K., and Williams, J.A. (1995) Antimalarial dyes revisited: xanthenes, azines, oxazines, and thiazines. Antimicrob. Agents Chemother., 39, 2671-2677.
-
(1995)
Antimicrob. Agents Chemother.
, vol.39
, pp. 2671-2677
-
-
Vennerstrom, J.L.1
Makler, M.T.2
Angerhofer, C.K.3
Williams, J.A.4
-
106
-
-
0036497071
-
Novel phenothiazine antimalarials: synthesis, antimalarial activity, and inhibition of the formation of beta-haematin
-
Kalkanidis, M., Klonis, N., Tilley, L., and Deady, L.W. (2002) Novel phenothiazine antimalarials: synthesis, antimalarial activity, and inhibition of the formation of beta-haematin. Biochem. Pharmacol., 63, 833-842.
-
(2002)
Biochem. Pharmacol.
, vol.63
, pp. 833-842
-
-
Kalkanidis, M.1
Klonis, N.2
Tilley, L.3
Deady, L.W.4
-
107
-
-
9144221396
-
Methylene blue as an antimalarial agent
-
Schirmer, R.H., Coulibaly, B., Stich, A., Scheiwein, M., Merkle, H., Eubel, J., Becker, K. et al. (2003) Methylene blue as an antimalarial agent. Redox Rep., 8, 272-275.
-
(2003)
Redox Rep.
, vol.8
, pp. 272-275
-
-
Schirmer, R.H.1
Coulibaly, B.2
Stich, A.3
Scheiwein, M.4
Merkle, H.5
Eubel, J.6
Becker, K.7
-
108
-
-
43149119398
-
Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso
-
Zoungrana, A., Coulibaly, B., Sie, A., Walter-Sack, I., Mockenhaupt, F.P., Kouyate, B., Schirmer, R.H. et al. (2008) Safety and efficacy of methylene blue combined with artesunate or amodiaquine for uncomplicated falciparum malaria: a randomized controlled trial from Burkina Faso. PLoS One, 3, e1630.
-
(2008)
PLoS One
, vol.3
-
-
Zoungrana, A.1
Coulibaly, B.2
Sie, A.3
Walter-Sack, I.4
Mockenhaupt, F.P.5
Kouyate, B.6
Schirmer, R.H.7
-
109
-
-
67649817177
-
Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria: a randomised controlled trial
-
Coulibaly, B., Zoungrana, A., Mockenhaupt, F.P., Schirmer, R.H., Klose, C., Mansmann, U., Meissner, P.E. et al. (2009) Strong gametocytocidal effect of methylene blue-based combination therapy against falciparum malaria: a randomised controlled trial. PLoS One, 4, e5318.
-
(2009)
PLoS One
, vol.4
-
-
Coulibaly, B.1
Zoungrana, A.2
Mockenhaupt, F.P.3
Schirmer, R.H.4
Klose, C.5
Mansmann, U.6
Meissner, P.E.7
-
110
-
-
0029752982
-
Inhibition of hemozoin formation in Plasmodium falciparum trophozoite extracts by heme analogs: possible implication in the resistance to malaria conferred by the beta-thalassemia trait
-
Martiney, J.A.,Cerami, A., and Slater, A.F. (1996) Inhibition of hemozoin formation in Plasmodium falciparum trophozoite extracts by heme analogs: possible implication in the resistance to malaria conferred by the beta-thalassemia trait. Mol. Med., 2, 236-246.
-
(1996)
Mol. Med.
, vol.2
, pp. 236-246
-
-
Martiney, J.A.1
Cerami, A.2
Slater, A.F.3
-
111
-
-
0031007845
-
Non-iron porphyrins inhibit beta-haematin (malaria pigment) polymerisation
-
Basilico, N., Monti, D., Olliaro, P., and Taramelli, D. (1997) Non-iron porphyrins inhibit beta-haematin (malaria pigment) polymerisation. FEBS Lett., 409, 297-299.
-
(1997)
FEBS Lett.
, vol.409
, pp. 297-299
-
-
Basilico, N.1
Monti, D.2
Olliaro, P.3
Taramelli, D.4
-
112
-
-
0034731868
-
Metalloporphyrins inhibit beta-hematin (hemozoin) formation
-
Cole, K.A., Ziegler, J., Evans, C.A., and Wright, D.W. (2000) Metalloporphyrins inhibit beta-hematin (hemozoin) formation. J. Inorg. Biochem., 78, 109-115.
-
(2000)
J. Inorg. Biochem.
, vol.78
, pp. 109-115
-
-
Cole, K.A.1
Ziegler, J.2
Evans, C.A.3
Wright, D.W.4
-
113
-
-
0038686310
-
In vitro antimalarial activity of metalloporphyrins against Plasmodium falciparum
-
Begum, K., Kim, H.S., Kumar, V., Stojiljkovic, I., and Wataya, Y. (2003) In vitro antimalarial activity of metalloporphyrins against Plasmodium falciparum. Parasitol. Res., 90, 221-224.
-
(2003)
Parasitol. Res.
, vol.90
, pp. 221-224
-
-
Begum, K.1
Kim, H.S.2
Kumar, V.3
Stojiljkovic, I.4
Wataya, Y.5
-
114
-
-
38749124436
-
Bilirubin inhibits Plasmodium falciparum growth through the generation of reactive oxygen species
-
Kumar, S., Guha, M., Choubey, V., Maity, P., Srivastava, K., Puri, S.K., and Bandyopadhyay, U. (2008) Bilirubin inhibits Plasmodium falciparum growth through the generation of reactive oxygen species. Free Radic. Biol. Med., 44, 602-613.
-
(2008)
Free Radic. Biol. Med.
, vol.44
, pp. 602-613
-
-
Kumar, S.1
Guha, M.2
Choubey, V.3
Maity, P.4
Srivastava, K.5
Puri, S.K.6
Bandyopadhyay, U.7
-
115
-
-
38649134187
-
Antiplasmodial activity of [(aryl) arylsulfanylmethyl]pyridine
-
Kumar, S., Das, S.K., Dey, S., Maity, P., Guha, M., Choubey, V., Panda, G. et al. (2008) Antiplasmodial activity of [(aryl) arylsulfanylmethyl]pyridine. Antimicrob. Agents Chemother., 52, 705-715.
-
(2008)
Antimicrob. Agents Chemother.
, vol.52
, pp. 705-715
-
-
Kumar, S.1
Das, S.K.2
Dey, S.3
Maity, P.4
Guha, M.5
Choubey, V.6
Panda, G.7
-
116
-
-
32544437658
-
Diamidines as antitrypanosomal, antileishmanial and antimalarial agents
-
Werbovetz, K. (2006) Diamidines as antitrypanosomal, antileishmanial and antimalarial agents. Curr. Opin. Invest. Drugs, 7, 147-157.
-
(2006)
Curr. Opin. Invest. Drugs
, vol.7
, pp. 147-157
-
-
Werbovetz, K.1
-
117
-
-
0038742717
-
Pentamidine uptake and resistance in pathogenic protozoa: past, present and future
-
Bray, P.G., Barrett, M.P., Ward, S.A., and de Koning, H.P. (2003) Pentamidine uptake and resistance in pathogenic protozoa: past, present and future. Trends Parasitol., 19, 232-239.
-
(2003)
Trends Parasitol.
, vol.19
, pp. 232-239
-
-
Bray, P.G.1
Barrett, M.P.2
Ward, S.A.3
de Koning, H.P.4
-
118
-
-
0035037590
-
Diamidine compounds: selective uptake and targeting in Plasmodium falciparum
-
Stead, A.M., Bray, P.G., Edwards, I.G., DeKoning, H.P., Elford, B.C., Stocks,P.A., and Ward, S.A. (2001) Diamidine compounds: selective uptake and targeting in Plasmodium falciparum. Mol. Pharmacol., 59, 1298-1306.
-
(2001)
Mol. Pharmacol.
, vol.59
, pp. 1298-1306
-
-
Stead, A.M.1
Bray, P.G.2
Edwards, I.G.3
DeKoning, H.P.4
Elford, B.C.5
Stocks, P.A.6
Ward, S.A.7
-
119
-
-
0030965449
-
Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(III) coordination complexes
-
Goldberg, D.E., Sharma, V., Oksman, A., Gluzman, I.Y., Wellems, T.E., and Piwnica-Worms, D. (1997) Probing the chloroquine resistance locus of Plasmodium falciparum with a novel class of multidentate metal(III) coordination complexes. J. Biol. Chem., 272, 6567-6572.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 6567-6572
-
-
Goldberg, D.E.1
Sharma, V.2
Oksman, A.3
Gluzman, I.Y.4
Wellems, T.E.5
Piwnica-Worms, D.6
-
120
-
-
0344875966
-
New antimalarial drugs
-
Wiesner, J., Ortmann, R., Jomaa, H., and Schlitzer, M. (2003) New antimalarial drugs. Angew. Chem. Int. Ed. Engl., 42, 5274-5293.
-
(2003)
Angew. Chem. Int. Ed. Engl.
, vol.42
, pp. 5274-5293
-
-
Wiesner, J.1
Ortmann, R.2
Jomaa, H.3
Schlitzer, M.4
-
121
-
-
0036836673
-
Novel and potent anti-malarial agents
-
Brinner, K.M., Mi Kim, J., Habashita, H., Gluzman, I.Y., Goldberg, D.E., and Ellman, J.A. (2002) Novel and potent anti-malarial agents. Bioorg. Med. Chem., 10, 3649-3661.
-
(2002)
Bioorg. Med. Chem.
, vol.10
, pp. 3649-3661
-
-
Brinner, K.M.1
Mi Kim, J.2
Habashita, H.3
Gluzman, I.Y.4
Goldberg, D.E.5
Ellman, J.A.6
-
122
-
-
0036830285
-
Haem polymerase as a novel target of antimalarial action of cyproheptadine
-
Agrawal, R., Tripathi, R., Tekwani, B.L., Jain, S.K., Dutta, G.P., and Shukla, O.P. (2002)Haem polymerase as a novel target of antimalarial action of cyproheptadine. Biochem. Pharmacol., 64, 1399-1406.
-
(2002)
Biochem. Pharmacol.
, vol.64
, pp. 1399-1406
-
-
Agrawal, R.1
Tripathi, R.2
Tekwani, B.L.3
Jain, S.K.4
Dutta, G.P.5
Shukla, O.P.6
-
123
-
-
20444497377
-
Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound
-
Van Miert, S., Hostyn, S., Maes, B.U., Cimanga, K., Brun, R., Kaiser, M.,Matyus, P. et al. (2005) Isoneocryptolepine, a synthetic indoloquinoline alkaloid, as an antiplasmodial lead compound. J. Nat. Prod., 68, 674-677.
-
(2005)
J. Nat. Prod.
, vol.68
, pp. 674-677
-
-
Van Miert, S.1
Hostyn, S.2
Maes, B.U.3
Cimanga, K.4
Brun, R.5
Kaiser, M.6
Matyus, P.7
-
124
-
-
65649114459
-
Synthesis and antiplasmodial activity of aminoalkylamino-substituted neocryptolepine derivatives
-
El Sayed, I., Van der Veken, P., Steert, K., Dhooghe, L., Hostyn, S., Van Baelen, G., Lemiere, G. et al. (2009) Synthesis and antiplasmodial activity of aminoalkylamino-substituted neocryptolepine derivatives. J. Med. Chem., 52, 2979-2988.
-
(2009)
J. Med. Chem.
, vol.52
, pp. 2979-2988
-
-
El Sayed, I.1
Van der Veken, P.2
Steert, K.3
Dhooghe, L.4
Hostyn, S.5
Van Baelen, G.6
Lemiere, G.7
-
125
-
-
0036682302
-
Synthesis, cytotoxicity, and antiplasmodial and antitrypanosomal activity of new neocryptolepine derivatives
-
Jonckers, T.H., van Miert, S., Cimanga, K., Bailly, C., Colson, P., De Pauw-Gillet, M.C., van den Heuvel, H. et al. (2002) Synthesis, cytotoxicity, and antiplasmodial and antitrypanosomal activity of new neocryptolepine derivatives. J.Med. Chem., 45, 3497-3508.
-
(2002)
J.Med. Chem.
, vol.45
, pp. 3497-3508
-
-
Jonckers, T.H.1
van Miert, S.2
Cimanga, K.3
Bailly, C.4
Colson, P.5
De Pauw-Gillet, M.C.6
van den Heuvel, H.7
-
126
-
-
77957089074
-
-
Academic Press, New York
-
Bringmann, G. and Pokorny, F. (1995) The naphthylisoquinoline alkaloids, in The Alkaloids (ed. G. Cordell), Academic Press, New York, pp. 127-271.
-
(1995)
The naphthylisoquinoline alkaloids, in The Alkaloids (ed. G. Cordell)
, pp. 127-271
-
-
Bringmann, G.1
Pokorny, F.2
-
127
-
-
0029071624
-
Activities of extracts and naphthylisoquinoline alkaloids from Triphyophyllum peltatum, Ancistrocladus abbreviatus and Ancistrocladus barteri against Plasmodium berghei (Anka strain) in vitro
-
Francois, G., Bringmann, G., Dochez, C., Schneider, C., Timperman, G., and Ake Assi, L. (1995) Activities of extracts and naphthylisoquinoline alkaloids from Triphyophyllum peltatum, Ancistrocladus abbreviatus and Ancistrocladus barteri against Plasmodium berghei (Anka strain) in vitro. J. Ethnopharmacol., 46, 115-120.
-
(1995)
J. Ethnopharmacol.
, vol.46
, pp. 115-120
-
-
Francois, G.1
Bringmann, G.2
Dochez, C.3
Schneider, C.4
Timperman, G.5
Ake Assi, L.6
-
128
-
-
0040299136
-
Naphthylisoquinoline alkaloids against malaria: evaluation of the curative potentials of dioncophylline C and dioncopeltine A against Plasmodium berghei in vivo
-
Francois, G., Timperman, G., Eling, W., Assi, L.A., Holenz, J., and Bringmann, G. (1997) Naphthylisoquinoline alkaloids against malaria: evaluation of the curative potentials of dioncophylline C and dioncopeltine A against Plasmodium berghei in vivo. Antimicrob. Agents Chemother., 41, 2533-2539.
-
(1997)
Antimicrob. Agents Chemother.
, vol.41
, pp. 2533-2539
-
-
Francois, G.1
Timperman, G.2
Eling, W.3
Assi, L.A.4
Holenz, J.5
Bringmann, G.6
-
129
-
-
47549097018
-
The novel antimalarial compound dioncophylline C forms a complex with heme in solution
-
Schwedhelm, K.F., Horstmann, M., Faber, J.H., Reichert, Y., Bringmann, G., and Faber, C. (2007) The novel antimalarial compound dioncophylline C forms a complex with heme in solution. ChemMedChem, 2, 541-548.
-
(2007)
ChemMedChem
, vol.2
, pp. 541-548
-
-
Schwedhelm, K.F.1
Horstmann, M.2
Faber, J.H.3
Reichert, Y.4
Bringmann, G.5
Faber, C.6
-
130
-
-
20044367655
-
Antimalarial activities and therapeutic properties of febrifugine analogs
-
Jiang, S., Zeng, Q., Gettayacamin, M., Tungtaeng, A., Wannaying, S., Lim, A., Hansukjariya, P. et al. (2005) Antimalarial activities and therapeutic properties of febrifugine analogs. Antimicrob. Agents Chemother., 49, 1169-1176.
-
(2005)
Antimicrob. Agents Chemother.
, vol.49
, pp. 1169-1176
-
-
Jiang, S.1
Zeng, Q.2
Gettayacamin, M.3
Tungtaeng, A.4
Wannaying, S.5
Lim, A.6
Hansukjariya, P.7
|