Manipulation of the N-alkyl substituent in amodiaquine to overcome the verapamil-sensitive chloroquine resistance component

Antimicrobial Agents and Chemotherapy

Volumn 40, Issue 10, 1996, Pages 2345-2349

  Hawley, Shaun R ^a   Bray, Patrick G ^a   O'Neill, Paul M ^a   Naisbitt, Dean J ^a   Park, B Kevin ^a   Ward, Stephen A ^a  

^a UNIVERSITY OF LIVERPOOL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AMODIAQUINE; AMOPYROQUINE; ANTIMALARIAL AGENT; CHLOROQUINE; DEETHYLAMODIAQUINE; GLUTATHIONE; VERAPAMIL;

ANTIMALARIAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CROSS RESISTANCE; CYTOTOXICITY; DILUTION; DRUG ACCUMULATION; DRUG DESIGN; DRUG POTENCY; DRUG SENSITIVITY; DRUG STRUCTURE; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LIPOPHILICITY; NONHUMAN; PARTITION COEFFICIENT; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL;

EID: 0029817144     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.40.10.2345     Document Type: Article

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