Synthesis of novel thiourea, thiazolidinedione and thioparabanic acid derivatives of 4-aminoquinoline as potent antimalarials

Bioorganic and Medicinal Chemistry Letters

Volumn 19, Issue 9, 2009, Pages 2570-2573

  Sunduru, Naresh ^a   Srivastava, Kumkum ^a   Rajakumar, S ^a   Puri, S K ^a   Saxena, J K ^a   Chauhan, Prem M S ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

Author keywords

4 Aminoquinoline; Antimalarial; Plasmodium falciparum; Thiazolidinedione; Thioparabanic acid; Thiourea

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; 4 AMINOQUINOLINE; ANTIMALARIAL AGENT; CHLOROQUINE; HEMATIN; THIOPARABANIC ACID; THIOUREA DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBIOTIC RESISTANCE; ANTIMALARIAL ACTIVITY; ARTICLE; CONTROLLED STUDY; CYCLIZATION; CYTOTOXICITY; DRUG POTENCY; DRUG SCREENING; DRUG STRUCTURE; DRUG SYNTHESIS; IC 50; IN VITRO STUDY; NONHUMAN; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII;

AMINOQUINOLINES; ANIMALS; ANTIMALARIALS; CERCOPITHECUS AETHIOPS; CHEMISTRY, PHARMACEUTICAL; CHLOROQUINE; DRUG DESIGN; DRUG RESISTANCE; HUMANS; INHIBITORY CONCENTRATION 50; PLASMODIUM FALCIPARUM; PLASMODIUM YOELII; THIAZOLIDINEDIONES; THIOUREA; VERO CELLS;

PLASMODIUM FALCIPARUM; PLASMODIUM YOELII;

EID: 64349106120     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.03.026     Document Type: Article

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