-
1
-
-
0014650528
-
Chloroquine resistance in malaria: A deficiency of chloroquine binding
-
Fitch, C. D. Chloroquine resistance in malaria: a deficiency of chloroquine binding. Proc. Natl. Acad. Sci. USA 64:1181-1187 (1969).
-
(1969)
Proc. Natl. Acad. Sci. USA
, vol.64
, pp. 1181-1187
-
-
Fitch, C.D.1
-
2
-
-
0021978338
-
Chloroquine uptake by Plasmodium falciparum-infected human erythrocytes during in vitro culture and its relationship to chloroquine resistance. Antimicrob
-
Verdier, F., J. Le Bras, F. Clavier, I. Hatin, and M. Blayo. Chloroquine uptake by Plasmodium falciparum-infected human erythrocytes during in vitro culture and its relationship to chloroquine resistance. Antimicrob. Agents Chemother. 27:561-564 (1985).
-
(1985)
Agents Chemother.
, vol.27
, pp. 561-564
-
-
Verdier, F.1
Le Bras, J.2
Clavier, F.3
Hatin, I.4
Blayo, M.5
-
3
-
-
0023666563
-
Efflux of chloroquine from Plasmodium falciparum: Mechanism of chloroquine resistance
-
Krogstad, D. J., I. Y. Gluzman, D. E. Kyle, A. M. J. Oduola, S. K. Martin, W. K. Milhous, and P. H. Schlesinger. Efflux of chloroquine from Plasmodium falciparum: mechanism of chloroquine resistance. Science (Washington D. C.) 235:1283-1285 (1987).
-
(1987)
Science (Washington D. C.)
, vol.235
, pp. 1283-1285
-
-
Krogstad, D.J.1
Gluzman, I.Y.2
Kyle, D.E.3
Oduola, A.M.J.4
Martin, S.K.5
Milhous, W.K.6
Schlesinger, P.H.7
-
4
-
-
0026785608
-
Rapid chloroquine efflux phenotype in both chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum
-
Bray, P. G., R. E. Howells, G. Y. Ritchie, and S. A. Ward. Rapid chloroquine efflux phenotype in both chloroquine-sensitive and chloroquine-resistant Plasmodium falciparum. Biochem. Pharmacol. 44:1317-1324 (1992).
-
(1992)
Biochem. Pharmacol.
, vol.44
, pp. 1317-1324
-
-
Bray, P.G.1
Howells, R.E.2
Ritchie, G.Y.3
Ward, S.A.4
-
5
-
-
0027218689
-
Biochemistry of multidrug resistance mediated by the multidrug transporter
-
Gottesman, M. M., and I. Pastan. Biochemistry of multidrug resistance mediated by the multidrug transporter. Annu. Rev. Biochem. 62:385-427 (1993).
-
(1993)
Annu. Rev. Biochem.
, vol.62
, pp. 385-427
-
-
Gottesman, M.M.1
Pastan, I.2
-
6
-
-
0023137728
-
Reversal of chloroquine resistance in Plasmodium falciparum by verapamil
-
Martin, S. K., A. M. J. Oduola, and W. K. Milhous. Reversal of chloroquine resistance in Plasmodium falciparum by verapamil. Science (Washington D. C.) 235:899-901 (1987).
-
(1987)
Science (Washington D. C.)
, vol.235
, pp. 899-901
-
-
Martin, S.K.1
Oduola, A.M.J.2
Milhous, W.K.3
-
7
-
-
0015893137
-
Active outward transport of daunomycin in resistant Erlich ascites tumor cells
-
Danø, K. Active outward transport of daunomycin in resistant Erlich ascites tumor cells. Biochim. Biophys. Acta 323:466-483 (1973).
-
(1973)
Biochim. Biophys. Acta
, vol.323
, pp. 466-483
-
-
Danø, K.1
-
8
-
-
0018200435
-
Mechanisms of resistance to daunorubicin in Erlich ascites tumor cells
-
Skovsgaard, T. Mechanisms of resistance to daunorubicin in Erlich ascites tumor cells. Cancer Res. 38:1785-1791 (1978).
-
(1978)
Cancer Res.
, vol.38
, pp. 1785-1791
-
-
Skovsgaard, T.1
-
9
-
-
0026079215
-
Kinetic modelling of chloroquine uptake by malaria infected erythrocytes
-
Ginsburg, H., and W. D. Stein. Kinetic modelling of chloroquine uptake by malaria infected erythrocytes. Biochem. Pharmacol. 41:1463-1470 (1991).
-
(1991)
Biochem. Pharmacol.
, vol.41
, pp. 1463-1470
-
-
Ginsburg, H.1
Stein, W.D.2
-
10
-
-
0027953538
-
Relationship of global chloroquine transport and reversal of chloroquine resistance in P. falciparum
-
Bray, P. G., M. K. Boulter, G. Y. Ritchie, and S. A. Ward. Relationship of global chloroquine transport and reversal of chloroquine resistance in P. falciparum. Mol. Biol. Parasitol. 63:87-94 (1994).
-
(1994)
Mol. Biol. Parasitol.
, vol.63
, pp. 87-94
-
-
Bray, P.G.1
Boulter, M.K.2
Ritchie, G.Y.3
Ward, S.A.4
-
11
-
-
0029190287
-
The role of MDR protein in altered drug translocation across tumor cell membranes
-
Roepe, P. D. The role of MDR protein in altered drug translocation across tumor cell membranes. Biochim. Biophys. Acta 1241:385-406 (1995).
-
(1995)
Biochim. Biophys. Acta
, vol.1241
, pp. 385-406
-
-
Roepe, P.D.1
-
12
-
-
0025786518
-
A P-glycoprotein homologue of Plasmodium falciparum is localised on the digestive vacuole
-
Cowman, A. F., S. Karcz, D. Galatis, and J. G. Culvenor. A P-glycoprotein homologue of Plasmodium falciparum is localised on the digestive vacuole. J. Cell Biol. 113:1033-1045 (1991).
-
(1991)
J. Cell Biol.
, vol.113
, pp. 1033-1045
-
-
Cowman, A.F.1
Karcz, S.2
Galatis, D.3
Culvenor, J.G.4
-
13
-
-
0025305350
-
Chloroquine resistance not linked to to mdr-like gene in a Plasmodium falciparum cross
-
Wellems, T. E., L. J. Panton, I. Y. Gluzman, V. E. de Rosario, R. W. Gwadz, A. Walker-Jonah, and D. J. Krogstad. Chloroquine resistance not linked to to mdr-like gene in a Plasmodium falciparum cross. Nature (Lond.). 345: 253-255 (1990).
-
(1990)
Nature (Lond.).
, vol.345
, pp. 253-255
-
-
Wellems, T.E.1
Panton, L.J.2
Gluzman, I.Y.3
De Rosario, V.E.4
Gwadz, R.W.5
Walker-Jonah, A.6
Krogstad, D.J.7
-
14
-
-
0026209743
-
Minireview: Similarities and differences between the multidrug resistance phenotype of mammalian tumour cells and chloroquine resistance in Plasmodium falciparum
-
Karcz, S., and A. F. Cowman. Minireview: similarities and differences between the multidrug resistance phenotype of mammalian tumour cells and chloroquine resistance in Plasmodium falciparum. Exp. Parasitol. 73:233-240 (1991).
-
(1991)
Exp. Parasitol.
, vol.73
, pp. 233-240
-
-
Karcz, S.1
Cowman, A.F.2
-
15
-
-
0023072474
-
Activity of quinoline-containing antimalarials against chloroquine sensitive and resistant strains of Plasmodium falciparum in vitro
-
Geary, T. G., A. A. Divo, and J. B. Jensen. Activity of quinoline-containing antimalarials against chloroquine sensitive and resistant strains of Plasmodium falciparum in vitro. Trans. R. Soc. Trop. Med. Hyg. 81:499-503 (1987).
-
(1987)
Trans. R. Soc. Trop. Med. Hyg.
, vol.81
, pp. 499-503
-
-
Geary, T.G.1
Divo, A.A.2
Jensen, J.B.3
-
16
-
-
0024544340
-
A comparison of the in vitro activities of amodiaquine and desethylamodiaquine against isolates of Plasmodium falciparum
-
Childs, G. E., E. F. Boudreau, W. K. Milhous, T. Wimonwattratee, N. Pooyindee, L. Pang, and D. E. Davidson, Jr. A comparison of the in vitro activities of amodiaquine and desethylamodiaquine against isolates of Plasmodium falciparum. Am. J. Trop. Med. Hyg. 40:7-11 (1989).
-
(1989)
Am. J. Trop. Med. Hyg.
, vol.40
, pp. 7-11
-
-
Childs, G.E.1
Boudreau, E.F.2
Milhous, W.K.3
Wimonwattratee, T.4
Pooyindee, N.5
Pang, L.6
Davidson Jr., D.E.7
-
17
-
-
0028885560
-
The P-glycoprotein-mediated relative decrease in cytosolic free drug concentration is similar for several anthracyclines with varying lipophilicity
-
Mülder, H. S., H. Dekker, H. M. Pinedo, and J. Lankelma. The P-glycoprotein-mediated relative decrease in cytosolic free drug concentration is similar for several anthracyclines with varying lipophilicity. Biochem. Pharmacol. 50:967-974 (1995).
-
(1995)
Biochem. Pharmacol.
, vol.50
, pp. 967-974
-
-
Mülder, H.S.1
Dekker, H.2
Pinedo, H.M.3
Lankelma, J.4
-
18
-
-
0023898749
-
Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells
-
Zamora, J. M., H. L. Pearce, and W. T. Beck. Physical-chemical properties shared by compounds that modulate multidrug resistance in human leukemic cells. Mol. Pharmacol. 33:454-462 (1988).
-
(1988)
Mol. Pharmacol.
, vol.33
, pp. 454-462
-
-
Zamora, J.M.1
Pearce, H.L.2
Beck, W.T.3
-
19
-
-
0024338609
-
Amplification of the multidrug resistance gene in some chloroquine resistant isolates of P. falciparum
-
Foote, S. J., J. K. Thompson, A. F. Cowman, and D. J. Kemp. Amplification of the multidrug resistance gene in some chloroquine resistant isolates of P. falciparum. Cell 57:921-930 (1989).
-
(1989)
Cell
, vol.57
, pp. 921-930
-
-
Foote, S.J.1
Thompson, J.K.2
Cowman, A.F.3
Kemp, D.J.4
-
20
-
-
0028609975
-
Chloroquine resistance of Plasmodium falciparum: Further evidence for a lack of association with mutations of the pfmdr1 gene
-
Haruki, K., P. G. Bray, S. A. Ward, M. Hommel, and G. Y. Ritchie. Chloroquine resistance of Plasmodium falciparum: further evidence for a lack of association with mutations of the pfmdr1 gene. Trans. R. Soc. Trop. Med. Hyg. 88:694 (1994).
-
(1994)
Trans. R. Soc. Trop. Med. Hyg.
, vol.88
, pp. 694
-
-
Haruki, K.1
Bray, P.G.2
Ward, S.A.3
Hommel, M.4
Ritchie, G.Y.5
-
21
-
-
0028939017
-
Role of hepatic metabolism in the bioactivation and detoxification of amodiaquine
-
Jewell, H., J. L. Maggs, A. C. Harrison, P. M. O'Neill, J. E. Ruscoe, and B. K Park. Role of hepatic metabolism in the bioactivation and detoxification of amodiaquine. Xenobiotica 25:199-217 (1995).
-
(1995)
Xenobiotica
, vol.25
, pp. 199-217
-
-
Jewell, H.1
Maggs, J.L.2
Harrison, A.C.3
O'Neill, P.M.4
Ruscoe, J.E.5
Park, B.K.6
-
22
-
-
0023236937
-
The metabolism of 17-alpha-ethinylestradiol by human liver microsomes: Formation of catechol and chemically reactive metabolites
-
Purba, H. S., J. L. Maggs, M. L. Orme, D. J. Back, and B. K. Park. The metabolism of 17-alpha-ethinylestradiol by human liver microsomes: formation of catechol and chemically reactive metabolites. Br. J. Clin. Pharmacol. 23:447-453 (1987).
-
(1987)
Br. J. Clin. Pharmacol.
, vol.23
, pp. 447-453
-
-
Purba, H.S.1
Maggs, J.L.2
Orme, M.L.3
Back, D.J.4
Park, B.K.5
-
23
-
-
0030448652
-
4-Aminoquinoline resistance of Plasmodium falciparum: Insights from the study of amodiaquine uptake
-
Bray, P. G., S. R. Hawley, and S. A. Ward. 4-Aminoquinoline resistance of Plasmodium falciparum: insights from the study of amodiaquine uptake. Mol. Pharmacol. 50:1551-1558 (1996).
-
(1996)
Mol. Pharmacol.
, vol.50
, pp. 1551-1558
-
-
Bray, P.G.1
Hawley, S.R.2
Ward, S.A.3
-
24
-
-
0027202542
-
The potential of desipramine to reverse chloroquine resistance of Plasmodium falciparum is reduced by its binding to plasma protein
-
Boulter, M. K., Bray, P. G., Howells, R. E., and Ward, S. A. The potential of desipramine to reverse chloroquine resistance of Plasmodium falciparum is reduced by its binding to plasma protein. Trans. R. Soc. Trop. Med. Hyg. 87:303 (1993).
-
(1993)
Trans. R. Soc. Trop. Med. Hyg.
, vol.87
, pp. 303
-
-
Boulter, M.K.1
Bray, P.G.2
Howells, R.E.3
Ward, S.A.4
-
25
-
-
0028334009
-
Photoaffinity labeling of chloroquine binding proteins in Plasmodium falciparum
-
Foley, L., W. M. Deady, K. Ng, A. F. Cowman, and L. Tilley. Photoaffinity labeling of chloroquine binding proteins in Plasmodium falciparum. J. Biol. Chem. 269:6955-6961 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 6955-6961
-
-
Foley, L.1
Deady, W.M.2
Ng, K.3
Cowman, A.F.4
Tilley, L.5
-
26
-
-
0007740769
-
Susceptibility of human malaria parasites to chloroquine ia pH dependent
-
Yayon, A., Z. I. Cabantchik, and H. Ginsburg. Susceptibility of human malaria parasites to chloroquine ia pH dependent. Proc. Natl. Acad. Sci. USA 82:2784-2788 (1985).
-
(1985)
Proc. Natl. Acad. Sci. USA
, vol.82
, pp. 2784-2788
-
-
Yayon, A.1
Cabantchik, Z.I.2
Ginsburg, H.3
-
27
-
-
0015232554
-
Effects of deoxyglucose on platelet metabolism
-
Detwiler, T. C. Effects of deoxyglucose on platelet metabolism. Biochim. Biophys. Acta 244:303-310 (1971).
-
(1971)
Biochim. Biophys. Acta
, vol.244
, pp. 303-310
-
-
Detwiler, T.C.1
-
28
-
-
0028282022
-
Cotransport of salt and water in membrane proteins: Membrane proteins as osmotic engines
-
Zeuthen, T., and W. D. Stein. Cotransport of salt and water in membrane proteins: membrane proteins as osmotic engines. J. Membr. Biol. 137:179-195 (1994).
-
(1994)
J. Membr. Biol.
, vol.137
, pp. 179-195
-
-
Zeuthen, T.1
Stein, W.D.2
-
29
-
-
0027452387
-
i homeostasis in multidrug resistant (MDR) cells: Further characterization of a series of MDR cell lines expressing different levels of P-glycoprotein
-
i homeostasis in multidrug resistant (MDR) cells: further characterization of a series of MDR cell lines expressing different levels of P-glycoprotein. Biochemistry 32:11042-11056 (1993).
-
(1993)
Biochemistry
, vol.32
, pp. 11042-11056
-
-
Roepe, P.D.1
Yong Wei, L.2
Cruz, J.3
Carlson, D.4
-
30
-
-
0024338609
-
Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum
-
Foote, S. J., Thompson, J. K., Cowman, A. F., and Kemp, D. J. Amplification of the multidrug resistance gene in some chloroquine-resistant isolates of P. falciparum. Cell 57:921-930 (1989).
-
(1989)
Cell
, vol.57
, pp. 921-930
-
-
Foote, S.J.1
Thompson, J.K.2
Cowman, A.F.3
Kemp, D.J.4
-
31
-
-
0024356582
-
Amplification of a gene related to mammalian mdr genes in drug resistant P. falciparum
-
Wilson, C. M., A. E. Serrano, A. Wasley, M. P. Bogenshutz, A. H. Shankar, and D. F. Wirth. Amplification of a gene related to mammalian mdr genes in drug resistant P. falciparum. Science (Washington D. C.) 244:1184-1186 (1989).
-
(1989)
Science (Washington D. C.)
, vol.244
, pp. 1184-1186
-
-
Wilson, C.M.1
Serrano, A.E.2
Wasley, A.3
Bogenshutz, M.P.4
Shankar, A.H.5
Wirth, D.F.6
-
32
-
-
0027339057
-
Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand
-
Wilson, C. M., Volkman, S. K., Thaithong, S., Martin, R. K., Kyle, D. E., Milhous, W. K and Wirth, D. F. Amplification of pfmdr1 associated with mefloquine and halofantrine resistance in Plasmodium falciparum from Thailand. Mol. Biol. Parasitol. 57:151-160 (1993).
-
(1993)
Mol. Biol. Parasitol.
, vol.57
, pp. 151-160
-
-
Wilson, C.M.1
Volkman, S.K.2
Thaithong, S.3
Martin, R.K.4
Kyle, D.E.5
Milhous, W.K.6
Wirth, D.F.7
-
33
-
-
0027056692
-
Chloroquine resistant Plasmodium falciparum isolated from the Sudan lack two mutations in the pfmdr1 gene thought to be associated with chloroquine resistance
-
Awad-el-Kariem, F. M., Miles, M. A., and Warhurst, D. C. Chloroquine resistant Plasmodium falciparum isolated from the Sudan lack two mutations in the pfmdr1 gene thought to be associated with chloroquine resistance. Trans. R. Soc. Trop. Med. Hyg. 86:587-589 (1992).
-
(1992)
Trans. R. Soc. Trop. Med. Hyg.
, vol.86
, pp. 587-589
-
-
Awad-el-Kariem, F.M.1
Miles, M.A.2
Warhurst, D.C.3
-
34
-
-
0029047328
-
Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr1 gene of Plasmodium falciparum
-
Volkman, S. K., Cowman, A. F., and Wirth, D. F. Functional complementation of the ste6 gene of Saccharomyces cerevisiae with the pfmdr1 gene of Plasmodium falciparum. Proc. Natl. Acad. Sci. USA 92:8921-8925 (1995).
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 8921-8925
-
-
Volkman, S.K.1
Cowman, A.F.2
Wirth, D.F.3
-
35
-
-
0026328231
-
Genetic mapping of the chloroquine resistance locus on Plasmodium falciparum chromosome 7
-
Wellems, T. E., A. Walker-Jonah, and L. J. Panton. Genetic mapping of the chloroquine resistance locus on Plasmodium falciparum chromosome 7. Proc. Natl. Acad. Sci. USA 88:3382-3386 (1991).
-
(1991)
Proc. Natl. Acad. Sci. USA
, vol.88
, pp. 3382-3386
-
-
Wellems, T.E.1
Walker-Jonah, A.2
Panton, L.J.3
-
36
-
-
0029078559
-
Verapamil competes with doxorubicin for binding to anionic phospholipids resulting in increased internal concentrations and rates of passive transport of doxorubicin
-
Speelmans, G., R. W. H. M. Staffhorst, F. De Wolf and B. De Kruijff. Verapamil competes with doxorubicin for binding to anionic phospholipids resulting in increased internal concentrations and rates of passive transport of doxorubicin. Biochim. Biophys. Acta 1238:137-146 (1995).
-
(1995)
Biochim. Biophys. Acta
, vol.1238
, pp. 137-146
-
-
Speelmans, G.1
Staffhorst, R.W.H.M.2
De Wolf, F.3
De Kruijff, B.4
-
37
-
-
0027317292
-
The susceptibility of the human malaria parasite Plasmodium falciparum to quinoline-containing drugs is correlated to the lipid composition of the infected erythrocyte membranes
-
Shalmiev, G., and H. Ginsburg. The susceptibility of the human malaria parasite Plasmodium falciparum to quinoline-containing drugs is correlated to the lipid composition of the infected erythrocyte membranes. Biochem. Pharmacol. 46:365-374 (1993).
-
(1993)
Biochem. Pharmacol.
, vol.46
, pp. 365-374
-
-
Shalmiev, G.1
Ginsburg, H.2
|