Haem polymerase as a novel target of antimalarial action of cyproheptadine

Biochemical Pharmacology

Volumn 64, Issue 9, 2002, Pages 1399-1406

  Agrawal, Rashmi ^a,b   Tripathi, Renu ^a   Tekwani, Babu L ^a   Jain, S K ^b   Dutta, Guru P ^a   Shukla, Onkar P ^a  

^a CENTRAL DRUG RESEARCH INSTITUTE   (India)

^b HAMDARD UNIVERSITY   (India)

Author keywords

Chloroquine; Cyproheptadine; Haem polymerase; Haemozoin; Malaria; Plasmodium yoelii nigeriensis

Indexed keywords

ANTIMALARIAL AGENT; CELL EXTRACT; CHLOROQUINE; CYPROHEPTADINE; HEMOPROTEIN; MEFLOQUINE; QUININE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIMALARIAL ACTIVITY; ARTICLE; BLOOD; CONTROLLED STUDY; DEATH; DOSE RESPONSE; DRUG FATALITY; DRUG MECHANISM; DRUG POTENTIATION; DRUG TARGETING; FEMALE; MALARIA; MALE; MOUSE; MULTIDRUG RESISTANCE; NONHUMAN; PLASMODIUM YOELII NIGERIENSIS; PRIORITY JOURNAL; PROTEIN POLYMERIZATION; SPOROZOON; TREATMENT OUTCOME;

ANIMALS; ANTIMALARIALS; CHLOROQUINE; CYPROHEPTADINE; DISEASE MODELS, ANIMAL; DRUG RESISTANCE; ENZYME INHIBITORS; HEMEPROTEINS; MEFLOQUINE; MICE; PLASMODIUM YOELII; QUININE; TRANSFERASES; TREATMENT OUTCOME;

EID: 0036830285     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-2952(02)01299-6     Document Type: Article

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