-
1
-
-
33745536739
-
Functional consequences of NOD2 (CARD15) mutations
-
Abraham C, Cho JH (2006). Functional consequences of NOD2 (CARD15) mutations. Inflamm Bowel Dis 12: 641-650.
-
(2006)
Inflamm Bowel Dis
, vol.12
, pp. 641-650
-
-
Abraham, C.1
Cho, J.H.2
-
2
-
-
70949107842
-
Inflammatory bowel disease
-
Abraham C, Cho JH (2009). Inflammatory bowel disease. N Engl J Med 361: 2066-2078.
-
(2009)
N Engl J Med
, vol.361
, pp. 2066-2078
-
-
Abraham, C.1
Cho, J.H.2
-
4
-
-
77955890952
-
Interleukin-23 drives intestinal inflammation through direct activity on T cells
-
Ahern PP, Schiering C, Buonocore S et al (2010). Interleukin-23 drives intestinal inflammation through direct activity on T cells. Immunity 33: 279-288.
-
(2010)
Immunity
, vol.33
, pp. 279-288
-
-
Ahern, P.P.1
Schiering, C.2
Buonocore, S.3
-
5
-
-
0036202336
-
The molecular classification of the clinical manifestations of Crohn's disease
-
Ahmad T, Armuzzi A, Bunce M et al (2002). The molecular classification of the clinical manifestations of Crohn's disease. Gastroenterology 122: 854-866.
-
(2002)
Gastroenterology
, vol.122
, pp. 854-866
-
-
Ahmad, T.1
Armuzzi, A.2
Bunce, M.3
-
6
-
-
27644562698
-
Crohn's disease patients carrying Nod2/CARD15 gene variants have an increased and early need for first surgery due to stricturing disease and higher rate of surgical recurrence
-
Alvarez-Lobos M, Arostegui JI, Sans M et al (2005). Crohn's disease patients carrying Nod2/CARD15 gene variants have an increased and early need for first surgery due to stricturing disease and higher rate of surgical recurrence. Ann Surg 242: 693-700.
-
(2005)
Ann Surg
, vol.242
, pp. 693-700
-
-
Alvarez-Lobos, M.1
Arostegui, J.I.2
Sans, M.3
-
7
-
-
48549107534
-
Double contrast small-bowel radiography in the preoperative assessment of Crohn's disease: is it still useful?
-
Angriman I, Scarpa M, Ruffolo C et al (2008). Double contrast small-bowel radiography in the preoperative assessment of Crohn's disease: is it still useful? Surg Today 38: 700-704.
-
(2008)
Surg Today
, vol.38
, pp. 700-704
-
-
Angriman, I.1
Scarpa, M.2
Ruffolo, C.3
-
8
-
-
44349132270
-
Epithelial-cell recognition of commensal flora and maintenance of immune homeostasis in the gut
-
Artis D (2008). Epithelial-cell recognition of commensal flora and maintenance of immune homeostasis in the gut. Nat Rev Immunol 8: 411-421.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 411-421
-
-
Artis, D.1
-
9
-
-
18344410191
-
Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in Crohn's disease and experimental colitis in vivo
-
Atreya R, Mudter J, Finotto S et al (2000). Blockade of interleukin 6 trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in Crohn's disease and experimental colitis in vivo. Nat Med 6: 583-588.
-
(2000)
Nat Med
, vol.6
, pp. 583-588
-
-
Atreya, R.1
Mudter, J.2
Finotto, S.3
-
10
-
-
75449114677
-
Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease
-
Baert F, Moortgat L, van Assche G et al (2010). Mucosal healing predicts sustained clinical remission in patients with early-stage Crohn's disease. Gastroenterology 138: 463-468.
-
(2010)
Gastroenterology
, vol.138
, pp. 463-468
-
-
Baert, F.1
Moortgat, L.2
van Assche, G.3
-
11
-
-
70049098536
-
Regulatory T cells reinforce intestinal homeostasis
-
Barnes MJ, Powrie F (2009). Regulatory T cells reinforce intestinal homeostasis. Immunity 31: 401-411.
-
(2009)
Immunity
, vol.31
, pp. 401-411
-
-
Barnes, M.J.1
Powrie, F.2
-
12
-
-
48349136889
-
Genome wide association defines more than 30 distinct susceptibility loci for Crohn's disease
-
Barrett JC, Hansoul S, Nicolae DL et al (2008). Genome wide association defines more than 30 distinct susceptibility loci for Crohn's disease. Nat Genet 40: 955-962.
-
(2008)
Nat Genet
, vol.40
, pp. 955-962
-
-
Barrett, J.C.1
Hansoul, S.2
Nicolae, D.L.3
-
13
-
-
34248136828
-
Inflammatory bowel disease: cause and immunobiology
-
Baumgart DC, Carding SR (2007). Inflammatory bowel disease: cause and immunobiology. Lancet 369: 1627-1640.
-
(2007)
Lancet
, vol.369
, pp. 1627-1640
-
-
Baumgart, D.C.1
Carding, S.R.2
-
14
-
-
34248136340
-
Inflammatory bowel disease: clinical aspects and established and evolving therapies
-
Baumgart DC, Sandborn WJ (2007). Inflammatory bowel disease: clinical aspects and established and evolving therapies. Lancet 369: 1641-1657.
-
(2007)
Lancet
, vol.369
, pp. 1641-1657
-
-
Baumgart, D.C.1
Sandborn, W.J.2
-
15
-
-
70449100743
-
Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study
-
Beaugerie L, Brousse N, Bouvier AM et al (2009). Lymphoproliferative disorders in patients receiving thiopurines for inflammatory bowel disease: a prospective observational cohort study. Lancet 374: 1617-1625.
-
(2009)
Lancet
, vol.374
, pp. 1617-1625
-
-
Beaugerie, L.1
Brousse, N.2
Bouvier, A.M.3
-
16
-
-
78649650481
-
Diagnosis and assessment of Crohn's disease: the present and the future
-
Benevento G, Avellini C, Terrosu G, Geraci M, Lodolo I, Sorrentino D (2010). Diagnosis and assessment of Crohn's disease: the present and the future. Expert Rev Gastroenterol Hepatol 4: 757-766.
-
(2010)
Expert Rev Gastroenterol Hepatol
, vol.4
, pp. 757-766
-
-
Benevento, G.1
Avellini, C.2
Terrosu, G.3
Geraci, M.4
Lodolo, I.5
Sorrentino, D.6
-
17
-
-
0030818752
-
A prospective randomized comparison between small bowel enteroclysis and small bowel follow-through in Crohn's disease
-
Bernstein CN, Boult IF, Greenberg HM, van der Putten W, Duffy G, Grahame GR (1997). A prospective randomized comparison between small bowel enteroclysis and small bowel follow-through in Crohn's disease. Gastroenterology 113: 390-398.
-
(1997)
Gastroenterology
, vol.113
, pp. 390-398
-
-
Bernstein, C.N.1
Boult, I.F.2
Greenberg, H.M.3
van der Putten, W.4
Duffy, G.5
Grahame, G.R.6
-
18
-
-
38749149901
-
European evidence-based Consensus on the management of ulcerative colitis: Special situations
-
Biancone L, Michetti P, Travis S et al (2008). European evidence-based Consensus on the management of ulcerative colitis: Special situations. J Crohn's Colitis 2: 63-92.
-
(2008)
J Crohn's Colitis
, vol.2
, pp. 63-92
-
-
Biancone, L.1
Michetti, P.2
Travis, S.3
-
19
-
-
33644829107
-
Complications of biological therapy for inflammatory bowel diseases
-
Blonski W, Lichtenstein GR (2006). Complications of biological therapy for inflammatory bowel diseases. Curr Opin Gastroenterol 22: 30-43.
-
(2006)
Curr Opin Gastroenterol
, vol.22
, pp. 30-43
-
-
Blonski, W.1
Lichtenstein, G.R.2
-
20
-
-
0036632961
-
Cutaneous manifestations of gastrointestinal diseases
-
Boh EE, al-Smadi RM (2002). Cutaneous manifestations of gastrointestinal diseases. Dermatol Clin 20: 533-546.
-
(2002)
Dermatol Clin
, vol.20
, pp. 533-546
-
-
Boh, E.E.1
al-Smadi, R.M.2
-
21
-
-
0029847082
-
Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis
-
Boirivant M, Pica R, De Maria R, Testi R, Pallone F, Strober W (1996). Stimulated human lamina propria T cells manifest enhanced Fas-mediated apoptosis. J Clin Invest 98: 2616-2622.
-
(1996)
J Clin Invest
, vol.98
, pp. 2616-2622
-
-
Boirivant, M.1
Pica, R.2
De Maria, R.3
Testi, R.4
Pallone, F.5
Strober, W.6
-
22
-
-
0033011679
-
Lamina propria T cells in Crohn's disease and other gastrointestinal inflammation show defective CD2 pathway-induced apoptosis
-
Boirivant M, Marini M, Di Felice G et al (1999). Lamina propria T cells in Crohn's disease and other gastrointestinal inflammation show defective CD2 pathway-induced apoptosis. Gastroenterology 116: 557-565.
-
(1999)
Gastroenterology
, vol.116
, pp. 557-565
-
-
Boirivant, M.1
Marini, M.2
Di Felice, G.3
-
23
-
-
33845647693
-
Inhibition of Smad7 with a specific antisense oligonucleotide facilitates TGF-β1-mediated suppression of colitis
-
Boirivant M, Pallone F, Di Giacinto C et al (2006). Inhibition of Smad7 with a specific antisense oligonucleotide facilitates TGF-β1-mediated suppression of colitis. Gastroenterology 131: 1786-1798.
-
(2006)
Gastroenterology
, vol.131
, pp. 1786-1798
-
-
Boirivant, M.1
Pallone, F.2
Di Giacinto, C.3
-
24
-
-
0142053206
-
The immunological and genetic basis of inflammatory bowel disease
-
Bouma G, Strober W (2003). The immunological and genetic basis of inflammatory bowel disease. Nat Rev Immunol 3: 521-533.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 521-533
-
-
Bouma, G.1
Strober, W.2
-
25
-
-
0028236232
-
Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease
-
Breese EJ, Michie CA, Nicholls SW et al (1994). Tumor necrosis factor alpha-producing cells in the intestinal mucosa of children with inflammatory bowel disease. Gastroenterology 106: 1455-1466.
-
(1994)
Gastroenterology
, vol.106
, pp. 1455-1466
-
-
Breese, E.J.1
Michie, C.A.2
Nicholls, S.W.3
-
26
-
-
33646875285
-
Meta-analysis: colorectal and small bowel cancer risk in patients with Crohn's disease
-
Canavan C, Abrams KR, Mayberry J (2006). Meta-analysis: colorectal and small bowel cancer risk in patients with Crohn's disease. Aliment Pharmacol Ther 23: 1097-1104.
-
(2006)
Aliment Pharmacol Ther
, vol.23
, pp. 1097-1104
-
-
Canavan, C.1
Abrams, K.R.2
Mayberry, J.3
-
28
-
-
4344602852
-
Guidelines for the management of inflammatory bowel disease in adults
-
IBD Section BSoG
-
Carter MJ, Lobo AJ, Travis SP, IBD Section BSoG (2004). Guidelines for the management of inflammatory bowel disease in adults. Gut 53(Suppl 5): V1-V16.
-
(2004)
Gut
, vol.53
, Issue.SUPPL. 5
-
-
Carter, M.J.1
Lobo, A.J.2
Travis, S.P.3
-
30
-
-
0348223787
-
Conversion of peripheral CD4+ CD25- naive T cells to CD4+ CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3
-
Chen W, Jin W, Hardegen N et al (2003). Conversion of peripheral CD4+ CD25- naive T cells to CD4+ CD25+ regulatory T cells by TGF-beta induction of transcription factor Foxp3. J Exp Med 198: 1875-1886.
-
(2003)
J Exp Med
, vol.198
, pp. 1875-1886
-
-
Chen, W.1
Jin, W.2
Hardegen, N.3
-
31
-
-
34848850085
-
The genetics of inflammatory bowel disease
-
Cho JH, Weaver CT (2007). The genetics of inflammatory bowel disease. Gastroenterology 133: 1327-1339.
-
(2007)
Gastroenterology
, vol.133
, pp. 1327-1339
-
-
Cho, J.H.1
Weaver, C.T.2
-
32
-
-
77958559432
-
Molecular reclassification of Crohn's disease by cluster analysis of genetic variants
-
Cleynen I, Mahachie John JM, Henckaerts L et al (2010). Molecular reclassification of Crohn's disease by cluster analysis of genetic variants. PLoS ONE 5: e12952.
-
(2010)
PLoS ONE
, vol.5
-
-
Cleynen, I.1
Mahachie John, J.M.2
Henckaerts, L.3
-
33
-
-
0347991877
-
The safety profile of infliximab in patients with Crohn's disease: the Mayo clinic experience in 500 patients
-
Colombel JF, Loftus EV Jr, Tremaine WJ et al (2004). The safety profile of infliximab in patients with Crohn's disease: the Mayo clinic experience in 500 patients. Gastroenterology 126: 19-31.
-
(2004)
Gastroenterology
, vol.126
, pp. 19-31
-
-
Colombel, J.F.1
Loftus Jr, E.V.2
Tremaine, W.J.3
-
34
-
-
44349167059
-
Dendritic cell in intestinal immune regulation
-
Coombes JL, Powrie F (2008). Dendritic cell in intestinal immune regulation. Nat Rev Immunol 8: 435-446.
-
(2008)
Nat Rev Immunol
, vol.8
, pp. 435-446
-
-
Coombes, J.L.1
Powrie, F.2
-
35
-
-
34547788180
-
A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-b and retinoic acid dependent mechanism
-
Coombes JL, Siddiqui KR, Arancibia-Càrcamo CV et al (2007). A functionally specialized population of mucosal CD103+ DCs induces Foxp3+ regulatory T cells via a TGF-b and retinoic acid dependent mechanism. J Exp Med 204: 1757-1764.
-
(2007)
J Exp Med
, vol.204
, pp. 1757-1764
-
-
Coombes, J.L.1
Siddiqui, K.R.2
Arancibia-Càrcamo, C.V.3
-
36
-
-
73849151394
-
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
-
Cooney R, Baker J, Brain O et al (2010). NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med 16: 90-97.
-
(2010)
Nat Med
, vol.16
, pp. 90-97
-
-
Cooney, R.1
Baker, J.2
Brain, O.3
-
37
-
-
2442651765
-
Tobacco and IBD: relevance in the understanding of disease mechanisms and clinical practice
-
Cosnes J (2004). Tobacco and IBD: relevance in the understanding of disease mechanisms and clinical practice. Best Pract Res Clin Gastroenterol 18: 481-496.
-
(2004)
Best Pract Res Clin Gastroenterol
, vol.18
, pp. 481-496
-
-
Cosnes, J.1
-
38
-
-
0036061640
-
Long-term evolution of disease behaviour of Crohn's disease
-
Cosnes J, Cattan S, Blain A et al (2002). Long-term evolution of disease behaviour of Crohn's disease. Inflamm Bowel Dis 8: 244-250.
-
(2002)
Inflamm Bowel Dis
, vol.8
, pp. 244-250
-
-
Cosnes, J.1
Cattan, S.2
Blain, A.3
-
39
-
-
72949107811
-
Translational mini-review series on Th17 Cells: function and regulation of human T helper 17 cells in health and disease
-
Crome SQ, Wang AY, Levings MK (2009). Translational mini-review series on Th17 Cells: function and regulation of human T helper 17 cells in health and disease. Clin Exp Immunol 159: 109-119.
-
(2009)
Clin Exp Immunol
, vol.159
, pp. 109-119
-
-
Crome, S.Q.1
Wang, A.Y.2
Levings, M.K.3
-
40
-
-
0036202885
-
The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease
-
Cuthbert AP, Fisher SA, Mirza MM et al (2002). The contribution of NOD2 gene mutations to the risk and site of disease in inflammatory bowel disease. Gastroenterology 122: 867-874.
-
(2002)
Gastroenterology
, vol.122
, pp. 867-874
-
-
Cuthbert, A.P.1
Fisher, S.A.2
Mirza, M.M.3
-
42
-
-
34247504544
-
Risks and benefits of biologic therapy for inflammatory bowel diseases
-
D'Haens GR (2007). Risks and benefits of biologic therapy for inflammatory bowel diseases. Gut 56: 725-732.
-
(2007)
Gut
, vol.56
, pp. 725-732
-
-
D'Haens, G.R.1
-
43
-
-
76949095663
-
Top-down therapy for IBD: rationale and requisite evidence
-
D'Haens GR (2010). Top-down therapy for IBD: rationale and requisite evidence. Nat Rev Gastroenterol Hepatol 7: 86-92.
-
(2010)
Nat Rev Gastroenterol Hepatol
, vol.7
, pp. 86-92
-
-
D'Haens, G.R.1
-
44
-
-
0031915148
-
Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum
-
D'Haens GR, Geboes K, Peeters M, Baert F, Penninckx F, Rutgeerts P (1998). Early lesions of recurrent Crohn's disease caused by infusion of intestinal contents in excluded ileum. Gastroenterology 114: 262-267.
-
(1998)
Gastroenterology
, vol.114
, pp. 262-267
-
-
D'Haens, G.R.1
Geboes, K.2
Peeters, M.3
Baert, F.4
Penninckx, F.5
Rutgeerts, P.6
-
45
-
-
39449085441
-
Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial
-
D'Haens G, Baert F, van Assche G et al (2008). Early combined immunosuppression or conventional management in patients with newly diagnosed Crohn's disease: an open randomised trial. Lancet 371: 660-667.
-
(2008)
Lancet
, vol.371
, pp. 660-667
-
-
D'Haens, G.1
Baert, F.2
van Assche, G.3
-
46
-
-
77949770445
-
Interventions for prevention of post-operative recurrence of Crohn's disease
-
Doherty G, Bennett G, Patil S, Cheifetz A, Moss AC (2009). Interventions for prevention of post-operative recurrence of Crohn's disease. Cochrane Database Syst Rev 4: CD006873.
-
(2009)
Cochrane Database Syst Rev
, vol.4
-
-
Doherty, G.1
Bennett, G.2
Patil, S.3
Cheifetz, A.4
Moss, A.C.5
-
47
-
-
0029586031
-
Tolerance exists towards resident intestinal flora but is broken in active inflammatory disease (IBD)
-
Duchmann R, Kaiser I, Hermann E, Mayet W, Ewe K, Meyer zum Büschenfelde KH (1995). Tolerance exists towards resident intestinal flora but is broken in active inflammatory disease (IBD). Clin Exp Immunol 102: 448-455.
-
(1995)
Clin Exp Immunol
, vol.102
, pp. 448-455
-
-
Duchmann, R.1
Kaiser, I.2
Hermann, E.3
Mayet, W.4
Ewe, K.5
Meyer zum Büschenfelde, K.H.6
-
48
-
-
0029931508
-
Bacteria-specific T-cell clones are selective in their reactivity towards different enterobacteria or H. pylori and increased in inflammatory bowel disease
-
Duchmann R, Marker-Hermann E, Meyer zum Buschenfelde KH (1996). Bacteria-specific T-cell clones are selective in their reactivity towards different enterobacteria or H. pylori and increased in inflammatory bowel disease. Scand J Immunol 44: 71-79.
-
(1996)
Scand J Immunol
, vol.44
, pp. 71-79
-
-
Duchmann, R.1
Marker-Hermann, E.2
Meyer zum Buschenfelde, K.H.3
-
49
-
-
70049099845
-
Immune responses to the microbiota at the intestinal mucosal surface
-
Duerkop BA, Vaishnava S, Hooper LV (2009). Immune responses to the microbiota at the intestinal mucosal surface. Immunity 31: 368-376.
-
(2009)
Immunity
, vol.31
, pp. 368-376
-
-
Duerkop, B.A.1
Vaishnava, S.2
Hooper, L.V.3
-
50
-
-
33845340501
-
A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
-
Duerr RH, Taylor KD, Brant SR et al (2006). A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 314: 1461-1463.
-
(2006)
Science
, vol.314
, pp. 1461-1463
-
-
Duerr, R.H.1
Taylor, K.D.2
Brant, S.R.3
-
51
-
-
0035080617
-
The risk of colorectal cancer in ulcerative colitis: a meta-analysis
-
Eaden JA, Abrams KR, Mayberry JF (2001). The risk of colorectal cancer in ulcerative colitis: a meta-analysis. Gut 48: 526-535.
-
(2001)
Gut
, vol.48
, pp. 526-535
-
-
Eaden, J.A.1
Abrams, K.R.2
Mayberry, J.F.3
-
52
-
-
11144279151
-
Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a meta-analysis
-
Economou M, Trikalinos TA, Loizou KT, Tsianos EV, Ioannidis JP (2004). Differential effects of NOD2 variants on Crohn's disease risk and phenotype in diverse populations: a meta-analysis. Am J Gastroenterol 99: 2393-2404.
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 2393-2404
-
-
Economou, M.1
Trikalinos, T.A.2
Loizou, K.T.3
Tsianos, E.V.4
Ioannidis, J.P.5
-
53
-
-
0025092693
-
Ulcerative colitis and colorectal cancer. A population-based study
-
Ekbom A, Helmick C, Zack M, Adami HO (1990). Ulcerative colitis and colorectal cancer. A population-based study. N Engl J Med 323: 1228-1233.
-
(1990)
N Engl J Med
, vol.323
, pp. 1228-1233
-
-
Ekbom, A.1
Helmick, C.2
Zack, M.3
Adami, H.O.4
-
54
-
-
28144437207
-
Paneth cells: their role in innate immunity and inflammatory disease
-
Elphick DA, Mahida YR (2005). Paneth cells: their role in innate immunity and inflammatory disease. Gut 54: 1802-1809.
-
(2005)
Gut
, vol.54
, pp. 1802-1809
-
-
Elphick, D.A.1
Mahida, Y.R.2
-
56
-
-
67649170980
-
Foxp3+ regulatory T cells: differentiation, specification, subphenotypes
-
Feuerer M, Hill JA, Mathis D, Benoist C (2009). Foxp3+ regulatory T cells: differentiation, specification, subphenotypes. Nat Immunol 10: 689-695.
-
(2009)
Nat Immunol
, vol.10
, pp. 689-695
-
-
Feuerer, M.1
Hill, J.A.2
Mathis, D.3
Benoist, C.4
-
57
-
-
35348857386
-
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
-
Frank DN, St Amand AL, Feldman RA, Boedeker EC, Harpaz N, Pace NR (2007). Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci USA 104: 13780-13785.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 13780-13785
-
-
Frank, D.N.1
St Amand, A.L.2
Feldman, R.A.3
Boedeker, E.C.4
Harpaz, N.5
Pace, N.R.6
-
58
-
-
61349102490
-
Inflammatory bowel disease
-
Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL et al, eds, 17th edn. McGraw Hill: New York
-
Friedman S, Blumberg R (2008). Inflammatory bowel disease. In: Fauci AS, Braunwald E, Kasper DL, Hauser SL, Longo DL, Jameson JL et al, eds Harrison's Principles of Internal Medicine, 17th edn. McGraw Hill: New York, pp. 1777-1789.
-
(2008)
Harrison's Principles of Internal Medicine
, pp. 1777-1789
-
-
Friedman, S.1
Blumberg, R.2
-
59
-
-
0037216498
-
Increased expression of interleukin 17 in inflammatory bowel disease
-
Fujino S, Andoh A, Bamba S et al (2003). Increased expression of interleukin 17 in inflammatory bowel disease. Gut 52: 65-70.
-
(2003)
Gut
, vol.52
, pp. 65-70
-
-
Fujino, S.1
Andoh, A.2
Bamba, S.3
-
60
-
-
0030209985
-
Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5
-
Fuss IJ, Neurath M, Boirivant M et al (1996). Disparate CD4+ lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5. J Immunol 157: 1261-1270.
-
(1996)
J Immunol
, vol.157
, pp. 1261-1270
-
-
Fuss, I.J.1
Neurath, M.2
Boirivant, M.3
-
61
-
-
0032718352
-
Anti-interleukin 12 treatment regulates apoptosis of Th1 T cells in experimental colitis in mice
-
Fuss IJ, Marth T, Neurath MF, Pearlstein GR, Jain A, Strober W (1999). Anti-interleukin 12 treatment regulates apoptosis of Th1 T cells in experimental colitis in mice. Gastroenterology 117: 1078-1088.
-
(1999)
Gastroenterology
, vol.117
, pp. 1078-1088
-
-
Fuss, I.J.1
Marth, T.2
Neurath, M.F.3
Pearlstein, G.R.4
Jain, A.5
Strober, W.6
-
62
-
-
85047690640
-
Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis
-
Fuss IJ, Heller F, Boirivant M et al (2004). Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis. J Clin Invest 113: 1490-1497.
-
(2004)
J Clin Invest
, vol.113
, pp. 1490-1497
-
-
Fuss, I.J.1
Heller, F.2
Boirivant, M.3
-
63
-
-
0008904204
-
Transabdominal bowel sonography for the detection of intestinal complications in Crohn's disease
-
Gasche C, Moser G, Turetschek K, Schober E, Moeschl P, Oberhuber G (1999). Transabdominal bowel sonography for the detection of intestinal complications in Crohn's disease. Gut 44: 112-117.
-
(1999)
Gut
, vol.44
, pp. 112-117
-
-
Gasche, C.1
Moser, G.2
Turetschek, K.3
Schober, E.4
Moeschl, P.5
Oberhuber, G.6
-
64
-
-
0002063230
-
A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998
-
Gasche C, Scholmerich J, Brynskov J et al (2000). A simple classification of Crohn's disease: report of the Working Party for the World Congresses of Gastroenterology, Vienna 1998. Inflamm Bowel Dis 6: 8-15.
-
(2000)
Inflamm Bowel Dis
, vol.6
, pp. 8-15
-
-
Gasche, C.1
Scholmerich, J.2
Brynskov, J.3
-
65
-
-
50649110056
-
Thiopurine-induced myelotoxicity in patients with inflammatory bowel disease: a review
-
Gisbert JP, Gomollón F (2008). Thiopurine-induced myelotoxicity in patients with inflammatory bowel disease: a review. Am J Gastroenterol 103: 1783-1800.
-
(2008)
Am J Gastroenterol
, vol.103
, pp. 1783-1800
-
-
Gisbert, J.P.1
Gomollón, F.2
-
66
-
-
34250797604
-
Thiopurine-induced liver injury in patients with inflammatory bowel disease: a systematic review
-
Gisbert JP, González-Lama Y, Maté J (2007). Thiopurine-induced liver injury in patients with inflammatory bowel disease: a systematic review. Am J Gastroenterol 102: 1518-1527.
-
(2007)
Am J Gastroenterol
, vol.102
, pp. 1518-1527
-
-
Gisbert, J.P.1
González-Lama, Y.2
Maté, J.3
-
68
-
-
0242674331
-
Etiology and management of recurrent aphtous stomatitis
-
Greenberg MS, Pinto A (2003). Etiology and management of recurrent aphtous stomatitis. Curr Infect Dis Rep 5: 194-198.
-
(2003)
Curr Infect Dis Rep
, vol.5
, pp. 194-198
-
-
Greenberg, M.S.1
Pinto, A.2
-
69
-
-
0023938309
-
Perforating and non-perforating indications for repeated operations in Crohn's disease: evidence for two clinical forms
-
Greenstein AJ, Lachman P, Sachar DB et al (1988). Perforating and non-perforating indications for repeated operations in Crohn's disease: evidence for two clinical forms. Gut 29: 588-592.
-
(1988)
Gut
, vol.29
, pp. 588-592
-
-
Greenstein, A.J.1
Lachman, P.2
Sachar, D.B.3
-
70
-
-
2442699228
-
Specificities of inflammatory bowel disease in childhood
-
Griffiths AM (2004). Specificities of inflammatory bowel disease in childhood. Best Pract Res Clin Gastroenterol 18: 509-523.
-
(2004)
Best Pract Res Clin Gastroenterol
, vol.18
, pp. 509-523
-
-
Griffiths, A.M.1
-
71
-
-
10644289386
-
Acute intestinal obstruction and NOD2/CARD15 mutations among Italian Crohn's disease patients
-
Guagnozzi D, Cossu A, Viscido A et al (2004). Acute intestinal obstruction and NOD2/CARD15 mutations among Italian Crohn's disease patients. Eur Rev Med Pharmacol Sci 8: 179-185.
-
(2004)
Eur Rev Med Pharmacol Sci
, vol.8
, pp. 179-185
-
-
Guagnozzi, D.1
Cossu, A.2
Viscido, A.3
-
72
-
-
34848893583
-
Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study
-
Gupta RB, Harpaz N, Itzkowitz S et al (2007). Histologic inflammation is a risk factor for progression to colorectal neoplasia in ulcerative colitis: a cohort study. Gastroenterology 133: 1099-1105.
-
(2007)
Gastroenterology
, vol.133
, pp. 1099-1105
-
-
Gupta, R.B.1
Harpaz, N.2
Itzkowitz, S.3
-
73
-
-
0037062228
-
Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study
-
Hampe J, Grebe J, Nikolaus S et al (2002). Association of NOD2 (CARD 15) genotype with clinical course of Crohn's disease: a cohort study. Lancet 359: 1661-1665.
-
(2002)
Lancet
, vol.359
, pp. 1661-1665
-
-
Hampe, J.1
Grebe, J.2
Nikolaus, S.3
-
74
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
Hampe J, Franke A, Rosenstiel P et al (2007). A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet 39: 207-211.
-
(2007)
Nat Genet
, vol.39
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
-
75
-
-
0035074301
-
Management of Crohn's disease in adults
-
Practice Parameters Committee of the American College of Gastroenterology
-
Hanauer SB, Sandborn W, Practice Parameters Committee of the American College of Gastroenterology (2001). Management of Crohn's disease in adults. Am J Gastroenterol 96: 635-643.
-
(2001)
Am J Gastroenterol
, vol.96
, pp. 635-643
-
-
Hanauer, S.B.1
Sandborn, W.2
-
76
-
-
0020524275
-
The differential diagnosis of pyostomatitis vegetans and its relation to bowel disease
-
Hansen LS, Silverman S Jr, Daniels TE (1983). The differential diagnosis of pyostomatitis vegetans and its relation to bowel disease. Oral Surg Oral Med Oral Pathol 55: 363-373.
-
(1983)
Oral Surg Oral Med Oral Pathol
, vol.55
, pp. 363-373
-
-
Hansen, L.S.1
Silverman Jr, S.2
Daniels, T.E.3
-
77
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington LE, Hatton RD, Mangan PR et al (2005). Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat Immunol 6: 1123-1132.
-
(2005)
Nat Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
-
78
-
-
24044515539
-
A prospective study of the oral manifestations of Crohn's disease
-
Harty S, Fleming P, Rowland M et al (2005). A prospective study of the oral manifestations of Crohn's disease. Clin Gastroenterol Hepatol 3: 886-891.
-
(2005)
Clin Gastroenterol Hepatol
, vol.3
, pp. 886-891
-
-
Harty, S.1
Fleming, P.2
Rowland, M.3
-
79
-
-
37649013801
-
Chronic stimulation of Nod2 mediates tolerance to bacterial products
-
Hedl M, Li J, Cho JH, Abraham C (2007). Chronic stimulation of Nod2 mediates tolerance to bacterial products. Proc Natl Acad Sci USA 104: 19440-19445.
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 19440-19445
-
-
Hedl, M.1
Li, J.2
Cho, J.H.3
Abraham, C.4
-
80
-
-
0018903830
-
Occurrence and outcome after primary treatment of anal fistulae in Crohn's disease
-
Hellers G, Bergstrand O, Ewerth S, Holmström B (1980). Occurrence and outcome after primary treatment of anal fistulae in Crohn's disease. Gut 21: 525-527.
-
(1980)
Gut
, vol.21
, pp. 525-527
-
-
Hellers, G.1
Bergstrand, O.2
Ewerth, S.3
Holmström, B.4
-
81
-
-
77957682295
-
ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis
-
Homer CR, Richmond AL, Rebert NA, Achkar JP, McDonald C (2010). ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis. Gastroenterology 139: 1630-1641.
-
(2010)
Gastroenterology
, vol.139
, pp. 1630-1641
-
-
Homer, C.R.1
Richmond, A.L.2
Rebert, N.A.3
Achkar, J.P.4
McDonald, C.5
-
83
-
-
0033565302
-
Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance
-
Ina K, Itoh J, Fukushima K et al (1999). Resistance of Crohn's disease T cells to multiple apoptotic signals is associated with a Bcl-2/Bax mucosal imbalance. J Immunol 163: 1081-1090.
-
(1999)
J Immunol
, vol.163
, pp. 1081-1090
-
-
Ina, K.1
Itoh, J.2
Fukushima, K.3
-
84
-
-
0026709751
-
Cytokine messenger RNA profiles in inflammatory bowel disease mucosa detected by polymerase chain reaction amplification
-
Isaacs KL, Sartor RB, Haskill S (1992). Cytokine messenger RNA profiles in inflammatory bowel disease mucosa detected by polymerase chain reaction amplification. Gastroenterology 103: 1587-1595.
-
(1992)
Gastroenterology
, vol.103
, pp. 1587-1595
-
-
Isaacs, K.L.1
Sartor, R.B.2
Haskill, S.3
-
85
-
-
21844437381
-
Treatment of Crohn's disease with anti-IL-6 receptor antibody
-
Ito H (2005). Treatment of Crohn's disease with anti-IL-6 receptor antibody. J Gastroenterol 40(Suppl. 16): 32-34.
-
(2005)
J Gastroenterol
, vol.40
, Issue.SUPPL. 16
, pp. 32-34
-
-
Ito, H.1
-
86
-
-
44649189089
-
Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery
-
Ito T, Hanabuchi S, Wang YH et al (2008). Two functional subsets of FOXP3+ regulatory T cells in human thymus and periphery. Immunity 28: 870-880.
-
(2008)
Immunity
, vol.28
, pp. 870-880
-
-
Ito, T.1
Hanabuchi, S.2
Wang, Y.H.3
-
87
-
-
5444262511
-
Toll-like receptor control of the adaptive immune responses
-
Iwasaki A, Medzhitov R (2004). Toll-like receptor control of the adaptive immune responses. Nat Immunol 5: 987-995.
-
(2004)
Nat Immunol
, vol.5
, pp. 987-995
-
-
Iwasaki, A.1
Medzhitov, R.2
-
88
-
-
41549160626
-
Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis
-
Izcue A, Hue S, Buonocore S et al (2008). Interleukin-23 restrains regulatory T cell activity to drive T cell-dependent colitis. Immunity 28: 559-570.
-
(2008)
Immunity
, vol.28
, pp. 559-570
-
-
Izcue, A.1
Hue, S.2
Buonocore, S.3
-
89
-
-
33645998460
-
Risk of intestinal cancer in inflammatory bowel disease: a population-based study from Olmsted County, Minnesota
-
Jess T, Loftus EV Jr, Velayos FS et al (2006). Risk of intestinal cancer in inflammatory bowel disease: a population-based study from Olmsted County, Minnesota. Gastroenterology 130: 1039-1046.
-
(2006)
Gastroenterology
, vol.130
, pp. 1039-1046
-
-
Jess, T.1
Loftus Jr, E.V.2
Velayos, F.S.3
-
90
-
-
0141449950
-
Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): requirement for GALT dendritic cells and adjuvant
-
Johansson-Lindbom B, Svensson M, Wurbel MA, Malissen B, Márquez G, Agace W (2003). Selective generation of gut tropic T cells in gut-associated lymphoid tissue (GALT): requirement for GALT dendritic cells and adjuvant. J Exp Med 198: 963-969.
-
(2003)
J Exp Med
, vol.198
, pp. 963-969
-
-
Johansson-Lindbom, B.1
Svensson, M.2
Wurbel, M.A.3
Malissen, B.4
Márquez, G.5
Agace, W.6
-
91
-
-
4644259997
-
Inflammatory bowel disease
-
Friedman SL, McQuaid KR, Grendell JH, eds, 2th Edn. Lange Medical Books/Mc Graw-Hill: New York.
-
Judge TA, Lichtenstein GR (2003). Inflammatory bowel disease. In: Friedman SL, McQuaid KR, Grendell JH, eds Current Diagnosis and Treatment in Gastroenterology, 2th Edn. Lange Medical Books/Mc Graw-Hill: New York, pp. 108-130.
-
(2003)
Current Diagnosis and Treatment in Gastroenterology
, pp. 108-130
-
-
Judge, T.A.1
Lichtenstein, G.R.2
-
92
-
-
34548316885
-
Dysplasia and cancer in inflammatory bowel disease 10years after diagnosis: results of a population-based European collaborative follow-up study
-
Katsanos KH, Vermeire S, Christodoulou DK et al (2007). Dysplasia and cancer in inflammatory bowel disease 10years after diagnosis: results of a population-based European collaborative follow-up study. Digestion 75: 113-121.
-
(2007)
Digestion
, vol.75
, pp. 113-121
-
-
Katsanos, K.H.1
Vermeire, S.2
Christodoulou, D.K.3
-
93
-
-
56549104968
-
IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease
-
Kobayashi T, Okamoto S, Hisamatsu T et al (2008). IL23 differentially regulates the Th1/Th17 balance in ulcerative colitis and Crohn's disease. Gut 57: 1682-1689.
-
(2008)
Gut
, vol.57
, pp. 1682-1689
-
-
Kobayashi, T.1
Okamoto, S.2
Hisamatsu, T.3
-
94
-
-
55149094300
-
Human CD25high Foxp3 positive regulatory T cells differentiate into IL-17-producing cells
-
Koenen HJ, Smeets RL, Vink PM, van Rijssen E, Boots AM, Joosten I (2008). Human CD25high Foxp3 positive regulatory T cells differentiate into IL-17-producing cells. Blood 112: 2340-2352.
-
(2008)
Blood
, vol.112
, pp. 2340-2352
-
-
Koenen, H.J.1
Smeets, R.L.2
Vink, P.M.3
van Rijssen, E.4
Boots, A.M.5
Joosten, I.6
-
95
-
-
3843109109
-
Ulcerative colitis practice guidelines in adults (update): American College of Gastroenterology, Practice Parameters Committee
-
Kornbluth A, Sachar DB (2004). Ulcerative colitis practice guidelines in adults (update): American College of Gastroenterology, Practice Parameters Committee. Am J Gastroenterol 99: 1371-1385.
-
(2004)
Am J Gastroenterol
, vol.99
, pp. 1371-1385
-
-
Kornbluth, A.1
Sachar, D.B.2
-
96
-
-
41949134167
-
Ulcerative proctitis: a review of pharmacotherapy and management
-
Lakatos PL, Lakatos L (2008). Ulcerative proctitis: a review of pharmacotherapy and management. Expert Opin Pharmacother 9: 741-749.
-
(2008)
Expert Opin Pharmacother
, vol.9
, pp. 741-749
-
-
Lakatos, P.L.1
Lakatos, L.2
-
97
-
-
0033725067
-
Metabolism of vitamin A and its active metabolite all-trans-retinoic acid in small intestinal enterocytes
-
Lampen A, Meyer S, Arnhold T, Nau H (2000). Metabolism of vitamin A and its active metabolite all-trans-retinoic acid in small intestinal enterocytes. J Pharmacol Exp Ther 295: 979-985.
-
(2000)
J Pharmacol Exp Ther
, vol.295
, pp. 979-985
-
-
Lampen, A.1
Meyer, S.2
Arnhold, T.3
Nau, H.4
-
98
-
-
77953409495
-
Current trends in inflammatory bowel disease: the natural history
-
Langholz E (2010). Current trends in inflammatory bowel disease: the natural history. Ther Adv Gastroenterol 3: 77-86.
-
(2010)
Ther Adv Gastroenterol
, vol.3
, pp. 77-86
-
-
Langholz, E.1
-
99
-
-
0028338424
-
Course of ulcerative colitis: analysis of changes in disease activity over years
-
Langholz E, Munkholm P, Davidsen M, Binder V (1994). Course of ulcerative colitis: analysis of changes in disease activity over years. Gastroenterology 107: 3-11.
-
(1994)
Gastroenterology
, vol.107
, pp. 3-11
-
-
Langholz, E.1
Munkholm, P.2
Davidsen, M.3
Binder, V.4
-
100
-
-
0029875942
-
Changes in extent of ulcerative colitis: a study on the course and prognostic factors
-
Langholz E, Munkholm P, Davidsen M, Nielsen OH, Binder V (1996). Changes in extent of ulcerative colitis: a study on the course and prognostic factors. Scand J Gastroenterol 31: 260-266.
-
(1996)
Scand J Gastroenterol
, vol.31
, pp. 260-266
-
-
Langholz, E.1
Munkholm, P.2
Davidsen, M.3
Nielsen, O.H.4
Binder, V.5
-
101
-
-
2442495097
-
Current concepts and controversies in surgery for IBD
-
Larson DW, Pemberton JH (2004). Current concepts and controversies in surgery for IBD. Gastroenterology 126: 1611-1619.
-
(2004)
Gastroenterology
, vol.126
, pp. 1611-1619
-
-
Larson, D.W.1
Pemberton, J.H.2
-
102
-
-
0036201577
-
CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease
-
Lesage S, Zouali H, Cézard JP et al (2002). CARD15/NOD2 mutational analysis and genotype-phenotype correlation in 612 patients with inflammatory bowel disease. Am J Hum Genet 70: 845-857.
-
(2002)
Am J Hum Genet
, vol.70
, pp. 845-857
-
-
Lesage, S.1
Zouali, H.2
Cézard, J.P.3
-
103
-
-
34548700796
-
Unveiling the roles of autophagy in innate and adaptive immunity
-
Levine B, Deretic V (2007). Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol 7: 767-777.
-
(2007)
Nat Rev Immunol
, vol.7
, pp. 767-777
-
-
Levine, B.1
Deretic, V.2
-
104
-
-
33644869450
-
American Gastroenterological Association Institute technical review on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease
-
American Gastroenterological Association.
-
Lichtenstein GR, Abreu MT, Cohen R, Tremaine W, American Gastroenterological Association (2006). American Gastroenterological Association Institute technical review on corticosteroids, immunomodulators, and infliximab in inflammatory bowel disease. Gastroenterology 130: 940-987.
-
(2006)
Gastroenterology
, vol.130
, pp. 940-987
-
-
Lichtenstein, G.R.1
Abreu, M.T.2
Cohen, R.3
Tremaine, W.4
-
105
-
-
0030029603
-
Prevalence of oral lesions in inflammatory bowel disease
-
Lisciandrano D, Ranzi T, Carrassi A et al (1996). Prevalence of oral lesions in inflammatory bowel disease. Am J Gastroenterol 91: 7-10.
-
(1996)
Am J Gastroenterol
, vol.91
, pp. 7-10
-
-
Lisciandrano, D.1
Ranzi, T.2
Carrassi, A.3
-
106
-
-
2442563304
-
Clinical epidemiology of inflammatory bowel disease: incidence, prevalence and environmental influences
-
Loftus EV Jr (2004). Clinical epidemiology of inflammatory bowel disease: incidence, prevalence and environmental influences. Gastroenterology 126: 1504-1517.
-
(2004)
Gastroenterology
, vol.126
, pp. 1504-1517
-
-
Loftus Jr, E.V.1
-
107
-
-
0036161786
-
The epidemiology and natural history of Crohn's disease in population based patient cohorts from North America: a systematic review
-
Loftus EV Jr, Schemed P, Sandborn WJ (2002). The epidemiology and natural history of Crohn's disease in population based patient cohorts from North America: a systematic review. Aliment Pharmacol Ther 16: 51-60.
-
(2002)
Aliment Pharmacol Ther
, vol.16
, pp. 51-60
-
-
Loftus Jr, E.V.1
Schemed, P.2
Sandborn, W.J.3
-
108
-
-
0035188740
-
Behaviour of Crohn's disease according to the Vienna classification: changing pattern over the course of the disease
-
Louis E, Collard A, Oger AF, Degroote E, Aboul Nasr El Yafi FA, Belaiche J (2001). Behaviour of Crohn's disease according to the Vienna classification: changing pattern over the course of the disease. Gut 49: 777-782.
-
(2001)
Gut
, vol.49
, pp. 777-782
-
-
Louis, E.1
Collard, A.2
Oger, A.F.3
Degroote, E.4
Aboul Nasr El Yafi, F.A.5
Belaiche, J.6
-
109
-
-
0025333699
-
Tumour necrosis factor alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine
-
MacDonald TT, Hutchings P, Choy MY, Murch S, Cooke A (1990). Tumour necrosis factor alpha and interferon-gamma production measured at the single cell level in normal and inflamed human intestine. Clin Exp Immunol 81: 301-305.
-
(1990)
Clin Exp Immunol
, vol.81
, pp. 301-305
-
-
MacDonald, T.T.1
Hutchings, P.2
Choy, M.Y.3
Murch, S.4
Cooke, A.5
-
110
-
-
44049104564
-
The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
-
Manel N, Unutmaz D, Littman DR (2008). The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat Immunol 9: 641-649.
-
(2008)
Nat Immunol
, vol.9
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
111
-
-
8344284998
-
Anti-interleukin-12 antibody for active Crohn's disease
-
Mannon PJ, Fuss IJ, Mayer L et al (2004). Anti-interleukin-12 antibody for active Crohn's disease. N Engl J Med 351: 2069-2079.
-
(2004)
N Engl J Med
, vol.351
, pp. 2069-2079
-
-
Mannon, P.J.1
Fuss, I.J.2
Mayer, L.3
-
112
-
-
17144400393
-
TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+ CD25+ regulatory T cells
-
Marie JC, Letterio JJ, Gavin M, Rudensky AY (2005). TGF-beta1 maintains suppressor function and Foxp3 expression in CD4+ CD25+ regulatory T cells. J Exp Med 201: 1061-1067.
-
(2005)
J Exp Med
, vol.201
, pp. 1061-1067
-
-
Marie, J.C.1
Letterio, J.J.2
Gavin, M.3
Rudensky, A.Y.4
-
113
-
-
38549087476
-
Innate immunity in inflammatory bowel disease: a disease hypothesis
-
Marks DJ, Segal AW (2008). Innate immunity in inflammatory bowel disease: a disease hypothesis. J Pathol 214: 260-266.
-
(2008)
J Pathol
, vol.214
, pp. 260-266
-
-
Marks, D.J.1
Segal, A.W.2
-
114
-
-
20444434616
-
Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease
-
Maul J, Loddenkemper C, Mundt P et al (2005). Peripheral and intestinal regulatory CD4+ CD25(high) T cells in inflammatory bowel disease. Gastroenterology 128: 1868-1878.
-
(2005)
Gastroenterology
, vol.128
, pp. 1868-1878
-
-
Maul, J.1
Loddenkemper, C.2
Mundt, P.3
-
115
-
-
55149111143
-
Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation
-
Maynard CL, Weaver CT (2008). Diversity in the contribution of interleukin-10 to T-cell-mediated immune regulation. Immunol Rev 226: 219-233.
-
(2008)
Immunol Rev
, vol.226
, pp. 219-233
-
-
Maynard, C.L.1
Weaver, C.T.2
-
116
-
-
0034894059
-
Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease
-
Monteleone G, Kumberova A, Croft NM, McKenzie C, Steer HV, MacDonald TT (2001). Blocking Smad7 restores TGF-beta1 signaling in chronic inflammatory bowel disease. J Clin Invest 108: 601-609.
-
(2001)
J Clin Invest
, vol.108
, pp. 601-609
-
-
Monteleone, G.1
Kumberova, A.2
Croft, N.M.3
McKenzie, C.4
Steer, H.V.5
MacDonald, T.T.6
-
117
-
-
0038264036
-
Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells
-
Mora JR, Bono MR, Manjunath N et al (2003). Selective imprinting of gut-homing T cells by Peyer's patch dendritic cells. Nature 424: 88-93.
-
(2003)
Nature
, vol.424
, pp. 88-93
-
-
Mora, J.R.1
Bono, M.R.2
Manjunath, N.3
-
118
-
-
0038316325
-
The anatomical basis of tolerance and immunity to intestinal antigens
-
Mowat AMcI (2003). The anatomical basis of tolerance and immunity to intestinal antigens. Nat Rev Immunol 3: 331-341.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 331-341
-
-
Mowat, AM.1
-
119
-
-
0027131566
-
Intestinal cancer risk and mortality in patients with Crohn's disease
-
Munkholm P, Langholz E, Davidsen M, Binder V (1993). Intestinal cancer risk and mortality in patients with Crohn's disease. Gastroenterology 105: 1716-1723.
-
(1993)
Gastroenterology
, vol.105
, pp. 1716-1723
-
-
Munkholm, P.1
Langholz, E.2
Davidsen, M.3
Binder, V.4
-
121
-
-
77955859925
-
Regulatory T-cell stability and plasticity in mucosal and systemic immune systems
-
Murai M, Krause P, Cheroutre H, Kronenberg M (2010). Regulatory T-cell stability and plasticity in mucosal and systemic immune systems. Mucosal Immunol 3: 443-449.
-
(2010)
Mucosal Immunol
, vol.3
, pp. 443-449
-
-
Murai, M.1
Krause, P.2
Cheroutre, H.3
Kronenberg, M.4
-
122
-
-
52149099867
-
Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance
-
Nedjic J, Aichinger M, Emmerich J, Mizushima N, Klein L (2008). Autophagy in thymic epithelium shapes the T-cell repertoire and is essential for tolerance. Nature 455: 396-400.
-
(2008)
Nature
, vol.455
, pp. 396-400
-
-
Nedjic, J.1
Aichinger, M.2
Emmerich, J.3
Mizushima, N.4
Klein, L.5
-
123
-
-
3442899939
-
NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease
-
Netea MG, Kullberg BJ, de Jong DJ et al (2004). NOD2 mediates anti-inflammatory signals induced by TLR2 ligands: implications for Crohn's disease. J Immunol 34: 2052-2059.
-
(2004)
J Immunol
, vol.34
, pp. 2052-2059
-
-
Netea, M.G.1
Kullberg, B.J.2
de Jong, D.J.3
-
124
-
-
0028861975
-
Antibodies to IL-12 abrogate established experimental colitis in mice
-
Neurath MF, Fuss IJ, Kelsall BL, Stüber E, Strober W (1995). Antibodies to IL-12 abrogate established experimental colitis in mice. J Exp Med 182: 1281-1290.
-
(1995)
J Exp Med
, vol.182
, pp. 1281-1290
-
-
Neurath, M.F.1
Fuss, I.J.2
Kelsall, B.L.3
Stüber, E.4
Strober, W.5
-
125
-
-
0021989902
-
Pyostomatitis vegetans
-
Neville BW, Smith SE, Maize JC, Laden SA, Denton WT (1985). Pyostomatitis vegetans. Am J Dermatopathol 7: 69-77.
-
(1985)
Am J Dermatopathol
, vol.7
, pp. 69-77
-
-
Neville, B.W.1
Smith, S.E.2
Maize, J.C.3
Laden, S.A.4
Denton, W.T.5
-
126
-
-
36349023798
-
Blocking of IL-6 signaling pathway prevents CD4+ T cell-mediated colitis in a T(h)17-independent manner
-
Noguchi D, Wakita D, Tajima M et al (2007). Blocking of IL-6 signaling pathway prevents CD4+ T cell-mediated colitis in a T(h)17-independent manner. Int Immunol 19: 1431-1440.
-
(2007)
Int Immunol
, vol.19
, pp. 1431-1440
-
-
Noguchi, D.1
Wakita, D.2
Tajima, M.3
-
127
-
-
0033638507
-
Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biologic activities similar as well as distinct from IL-12
-
Oppmann B, Lesley R, Blom B et al (2000). Novel p19 protein engages IL-12p40 to form a cytokine, IL-23, with biologic activities similar as well as distinct from IL-12. Immunity 13: 715-725.
-
(2000)
Immunity
, vol.13
, pp. 715-725
-
-
Oppmann, B.1
Lesley, R.2
Blom, B.3
-
129
-
-
77951975185
-
The impact of thiopurines on the risk of surgical recurrence in patients with Crohn' s Disease after first intestinal surgery
-
Papay P, Reinisch W, Ho E et al (2010). The impact of thiopurines on the risk of surgical recurrence in patients with Crohn' s Disease after first intestinal surgery. Am J Gastroenterol 105: 1158-1164.
-
(2010)
Am J Gastroenterol
, vol.105
, pp. 1158-1164
-
-
Papay, P.1
Reinisch, W.2
Ho, E.3
-
130
-
-
27544465354
-
A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17
-
Park H, Li Z, Yang XO et al (2005). A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17. Nat Immunol 6: 1133-1141.
-
(2005)
Nat Immunol
, vol.6
, pp. 1133-1141
-
-
Park, H.1
Li, Z.2
Yang, X.O.3
-
131
-
-
43249097073
-
CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells
-
Perruche S, Zhang P, Liu Y, Saas P, Bluestone JA, Chen W (2008). CD3-specific antibody-induced immune tolerance involves transforming growth factor-beta from phagocytes digesting apoptotic T cells. Nat Med 14: 528-535.
-
(2008)
Nat Med
, vol.14
, pp. 528-535
-
-
Perruche, S.1
Zhang, P.2
Liu, Y.3
Saas, P.4
Bluestone, J.A.5
Chen, W.6
-
133
-
-
0026034309
-
Oral manifestations of Crohn's disease. An analysis of 79 cases
-
Plauth M, Jenss H, Meyle J (1991). Oral manifestations of Crohn's disease. An analysis of 79 cases. J Clin Gastroenterol 13: 29-37.
-
(1991)
J Clin Gastroenterol
, vol.13
, pp. 29-37
-
-
Plauth, M.1
Jenss, H.2
Meyle, J.3
-
134
-
-
0036598567
-
Ultrasound and magnetic resonance imaging in Crohn's disease: a comparison
-
Potthast S, Rieber A, von Tirpitz C, Wruk D, Adler G, Brambs HJ (2002). Ultrasound and magnetic resonance imaging in Crohn's disease: a comparison. Eur Radiol 12: 1416-1422.
-
(2002)
Eur Radiol
, vol.12
, pp. 1416-1422
-
-
Potthast, S.1
Rieber, A.2
von Tirpitz, C.3
Wruk, D.4
Adler, G.5
Brambs, H.J.6
-
137
-
-
0025931643
-
Activation and signaling status of human lamina propria T lymphocytes
-
Qiao L, Schurmann G, Betzler M, Meuer SC (1991). Activation and signaling status of human lamina propria T lymphocytes. Gastroenterology 101: 1529-1536.
-
(1991)
Gastroenterology
, vol.101
, pp. 1529-1536
-
-
Qiao, L.1
Schurmann, G.2
Betzler, M.3
Meuer, S.C.4
-
138
-
-
77955096659
-
Natural history of Crohn's disease in a population-based cohort from Cardiff (1986-2003): a study of changes in medical treatment and surgical resection rates
-
Ramadas AV, Gunesh S, Thomas GA, Williams GT, Hawthorne AB (2010). Natural history of Crohn's disease in a population-based cohort from Cardiff (1986-2003): a study of changes in medical treatment and surgical resection rates. Gut 59: 1200-1206.
-
(2010)
Gut
, vol.59
, pp. 1200-1206
-
-
Ramadas, A.V.1
Gunesh, S.2
Thomas, G.A.3
Williams, G.T.4
Hawthorne, A.B.5
-
139
-
-
0029889689
-
Mucosal inflammatory cytokine production by intestinal biopsies in patients with ulcerative colitis and Crohn's disease
-
Reimund JM, Wittersheim C, Dumont S et al (1996). Mucosal inflammatory cytokine production by intestinal biopsies in patients with ulcerative colitis and Crohn's disease. J Clin Immunol 16: 144-150.
-
(1996)
J Clin Immunol
, vol.16
, pp. 144-150
-
-
Reimund, J.M.1
Wittersheim, C.2
Dumont, S.3
-
140
-
-
0027451455
-
Enhanced secretion of tumour necrosis factor-alpha IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease
-
Reinecker HC, Steffen M, Witthoeft T et al (1993). Enhanced secretion of tumour necrosis factor-alpha IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease. Clin Exp Immunol 94: 174-181.
-
(1993)
Clin Exp Immunol
, vol.94
, pp. 174-181
-
-
Reinecker, H.C.1
Steffen, M.2
Witthoeft, T.3
-
141
-
-
0033851776
-
MRI in the diagnosis of small bowel disease: use of positive and negative oral contrast media in combination with enteroclysis
-
Rieber A, Aschoff A, Nussle K et al (2000). MRI in the diagnosis of small bowel disease: use of positive and negative oral contrast media in combination with enteroclysis. Eur Radiol 10: 1377-1382.
-
(2000)
Eur Radiol
, vol.10
, pp. 1377-1382
-
-
Rieber, A.1
Aschoff, A.2
Nussle, K.3
-
142
-
-
0036629519
-
MRI of the abdomen with positive oral contrast agents for the diagnosis of inflammatory small bowel disease
-
Rieber A, Nussle K, Reinshagen M, Brambs HJ, Gabelmann A (2002). MRI of the abdomen with positive oral contrast agents for the diagnosis of inflammatory small bowel disease. Abdom Imaging 27: 394-399.
-
(2002)
Abdom Imaging
, vol.27
, pp. 394-399
-
-
Rieber, A.1
Nussle, K.2
Reinshagen, M.3
Brambs, H.J.4
Gabelmann, A.5
-
143
-
-
18244387204
-
Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells
-
Rimoldi M, Chieppa M, Salucci V et al (2005). Intestinal immune homeostasis is regulated by the crosstalk between epithelial cells and dendritic cells. Nat Immunol 6: 507-514.
-
(2005)
Nat Immunol
, vol.6
, pp. 507-514
-
-
Rimoldi, M.1
Chieppa, M.2
Salucci, V.3
-
144
-
-
0036737734
-
Radiological assessment of small bowel obstructions: value of conventional enteroclysis and dynamic MR-enteroclysis
-
Rohr A, Rohr D, Kuhbacher T, Schreiber S, Heller M, Reuter M (2002). Radiological assessment of small bowel obstructions: value of conventional enteroclysis and dynamic MR-enteroclysis. Rofo 174: 1158-1164.
-
(2002)
Rofo
, vol.174
, pp. 1158-1164
-
-
Rohr, A.1
Rohr, D.2
Kuhbacher, T.3
Schreiber, S.4
Heller, M.5
Reuter, M.6
-
145
-
-
33748319730
-
Extraintestinal manifestations and complications in inflammatory bowel diseases
-
Rothfuss KS, Stange EF, Herrlinger KR (2006). Extraintestinal manifestations and complications in inflammatory bowel diseases. World J Gastroenterol 12: 4819-4831.
-
(2006)
World J Gastroenterol
, vol.12
, pp. 4819-4831
-
-
Rothfuss, K.S.1
Stange, E.F.2
Herrlinger, K.R.3
-
146
-
-
67349250428
-
The gut microbiota shapes intestinal immune responses during health and disease
-
Round JL, Mazmanian SK (2009). The gut microbiota shapes intestinal immune responses during health and disease. Nat Rev Immunol 9: 313-323.
-
(2009)
Nat Rev Immunol
, vol.9
, pp. 313-323
-
-
Round, J.L.1
Mazmanian, S.K.2
-
147
-
-
77954738601
-
Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota
-
Round JL, Mazmanian SK (2010). Inducible Foxp3+ regulatory T-cell development by a commensal bacterium of the intestinal microbiota. Proc Natl Acad Sci USA 107: 12204-12209.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 12204-12209
-
-
Round, J.L.1
Mazmanian, S.K.2
-
148
-
-
72549107316
-
Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease
-
Rovedatti L, Kudo T, Biancheri P et al (2009). Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease. Gut 58: 1629-1636.
-
(2009)
Gut
, vol.58
, pp. 1629-1636
-
-
Rovedatti, L.1
Kudo, T.2
Biancheri, P.3
-
151
-
-
0025013473
-
Predictability of the postoperative course of Crohn's disease
-
Rutgeerts P, Geboes K, Vantrappen G, Beyls J, Kerremans R, Hiele M (1990). Predictability of the postoperative course of Crohn's disease. Gastroenterology 99: 956-963.
-
(1990)
Gastroenterology
, vol.99
, pp. 956-963
-
-
Rutgeerts, P.1
Geboes, K.2
Vantrappen, G.3
Beyls, J.4
Kerremans, R.5
Hiele, M.6
-
152
-
-
10744224387
-
Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease
-
Rutgeerts P, Feagan BG, Lichtenstein GR et al (2004). Comparison of scheduled and episodic treatment strategies of infliximab in Crohn's disease. Gastroenterology 126: 402-413.
-
(2004)
Gastroenterology
, vol.126
, pp. 402-413
-
-
Rutgeerts, P.1
Feagan, B.G.2
Lichtenstein, G.R.3
-
153
-
-
28844473957
-
Infliximab induction and maintenance therapy for ulcerative colitis
-
Rutgeerts P, Sandborn WJ, Feagan BG et al (2005). Infliximab induction and maintenance therapy for ulcerative colitis. N Engl J Med 353: 2462-2476.
-
(2005)
N Engl J Med
, vol.353
, pp. 2462-2476
-
-
Rutgeerts, P.1
Sandborn, W.J.2
Feagan, B.G.3
-
154
-
-
9344253340
-
Cancer surveillance in longstanding ulcerative colitis: endoscopic appearances help predict cancer risk
-
Rutter MD, Saunders BP, Wilkinson KH et al (2004). Cancer surveillance in longstanding ulcerative colitis: endoscopic appearances help predict cancer risk. Gut 53: 1813-1816.
-
(2004)
Gut
, vol.53
, pp. 1813-1816
-
-
Rutter, M.D.1
Saunders, B.P.2
Wilkinson, K.H.3
-
155
-
-
33645994506
-
Thirty-year analysis of a colonoscopic surveillance program for neoplasia in ulcerative colitis
-
Rutter MD, Saunders BP, Wilkinson KH et al (2006). Thirty-year analysis of a colonoscopic surveillance program for neoplasia in ulcerative colitis. Gastroenterology 130: 1030-1038.
-
(2006)
Gastroenterology
, vol.130
, pp. 1030-1038
-
-
Rutter, M.D.1
Saunders, B.P.2
Wilkinson, K.H.3
-
156
-
-
0036161216
-
A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn's disease
-
Sandborn WJ, Feagan BG, Hanauer SB et al (2002). A review of activity indices and efficacy endpoints for clinical trials of medical therapy in adults with Crohn's disease. Gastroenterology 122: 512-530.
-
(2002)
Gastroenterology
, vol.122
, pp. 512-530
-
-
Sandborn, W.J.1
Feagan, B.G.2
Hanauer, S.B.3
-
157
-
-
0242490195
-
AGA technical review on perianal Crohn's disease
-
American Gastroenterological Association Clinical Practice Committee
-
Sandborn WJ, Fazio VW, Feagan BG, Hanauer SB, American Gastroenterological Association Clinical Practice Committee (2003). AGA technical review on perianal Crohn's disease. Gastroenterology 125: 1508-1530.
-
(2003)
Gastroenterology
, vol.125
, pp. 1508-1530
-
-
Sandborn, W.J.1
Fazio, V.W.2
Feagan, B.G.3
Hanauer, S.B.4
-
158
-
-
53049091561
-
A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease
-
Sandborn WJ, Feagan BG, Fedorak RN et al (2008). A randomized trial of Ustekinumab, a human interleukin-12/23 monoclonal antibody, in patients with moderate-to-severe Crohn's disease. Gastroenterology 135: 1130-1141.
-
(2008)
Gastroenterology
, vol.135
, pp. 1130-1141
-
-
Sandborn, W.J.1
Feagan, B.G.2
Fedorak, R.N.3
-
159
-
-
57049168572
-
Fulminant colitis
-
Sands BE (2008). Fulminant colitis. J Gastrointest Surg 12: 2157-2159.
-
(2008)
J Gastrointest Surg
, vol.12
, pp. 2157-2159
-
-
Sands, B.E.1
-
160
-
-
0002739554
-
Antibiotics as therapeutic agents in Crohn's disease
-
Bayless TM, Hanauer S, eds Hamilton: Decker Inc
-
Sartor RB (2000). Antibiotics as therapeutic agents in Crohn's disease. In: Bayless TM, Hanauer S, eds Current Advanced Therapy of Inflammatory Bowel Disease. Hamilton: Decker Inc, pp. 359-362.
-
(2000)
Current Advanced Therapy of Inflammatory Bowel Disease
, pp. 359-362
-
-
Sartor, R.B.1
-
161
-
-
36249014365
-
Characterization of FOXP3+ CD4+ regulatory T cells in Crohn's disease
-
Saruta M, Yua QT, Fleshner PR et al (2007). Characterization of FOXP3+ CD4+ regulatory T cells in Crohn's disease. Clin Immunol 125: 281-290.
-
(2007)
Clin Immunol
, vol.125
, pp. 281-290
-
-
Saruta, M.1
Yua, Q.T.2
Fleshner, P.R.3
-
162
-
-
35748968209
-
In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid
-
Saurer L, McCullough KC, Summerfield A (2007). In vitro induction of mucosa-type dendritic cells by all-trans retinoic acid. J Immunol 179: 3504-3514.
-
(2007)
J Immunol
, vol.179
, pp. 3504-3514
-
-
Saurer, L.1
McCullough, K.C.2
Summerfield, A.3
-
163
-
-
0036598794
-
Oral aspects of Crohn's disease
-
Scheper HJ, Brand HS (2002). Oral aspects of Crohn's disease. Int Dent J 52: 163-182.
-
(2002)
Int Dent J
, vol.52
, pp. 163-182
-
-
Scheper, H.J.1
Brand, H.S.2
-
164
-
-
0036207249
-
The natural history of fistulizing Crohn's disease in Olmsted County, Minnesota
-
Schwartz DA, Loftus EV Jr, Tremaine WJ et al (2002). The natural history of fistulizing Crohn's disease in Olmsted County, Minnesota. Gastroenterology 122: 875-880.
-
(2002)
Gastroenterology
, vol.122
, pp. 875-880
-
-
Schwartz, D.A.1
Loftus Jr, E.V.2
Tremaine, W.J.3
-
165
-
-
0017162599
-
Neutrophil dysfunction in Crohn's disease
-
Segal AW, Loewi G (1976). Neutrophil dysfunction in Crohn's disease. Lancet 2: 219-221.
-
(1976)
Lancet
, vol.2
, pp. 219-221
-
-
Segal, A.W.1
Loewi, G.2
-
166
-
-
0032412057
-
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
-
Sellon RK, Tonkonogy S, Schultz M et al (1998). Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun 66: 5224-5231.
-
(1998)
Infect Immun
, vol.66
, pp. 5224-5231
-
-
Sellon, R.K.1
Tonkonogy, S.2
Schultz, M.3
-
167
-
-
33746345358
-
Risks and benefits of infliximab for the treatment of Crohn's disease
-
Siegel CA, Hur C, Korzenik JR, Gazelle GS, Sands BE (2006). Risks and benefits of infliximab for the treatment of Crohn's disease. Clin Gastroenterol Hepatol 4: 1017-1024.
-
(2006)
Clin Gastroenterol Hepatol
, vol.4
, pp. 1017-1024
-
-
Siegel, C.A.1
Hur, C.2
Korzenik, J.R.3
Gazelle, G.S.4
Sands, B.E.5
-
168
-
-
84894353884
-
Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a working party of the 2005 Montreal World Congress of Gastroenterology
-
Silverberg MS, Satsangi J, Ahmad T et al (2005). Toward an integrated clinical, molecular and serological classification of inflammatory bowel disease: report of a working party of the 2005 Montreal World Congress of Gastroenterology. Can J Gastroenterol 19(Suppl A): 5-36.
-
(2005)
Can J Gastroenterol
, vol.19
, Issue.SUPPL. A
, pp. 5-36
-
-
Silverberg, M.S.1
Satsangi, J.2
Ahmad, T.3
-
169
-
-
0035451799
-
Intestinal macrophages lack CD14 and CD89 and consequently are downregulated for LPS- and IgA-mediated activities
-
Smith PD, Smythies LE, Mosteller-Barnum M et al (2001). Intestinal macrophages lack CD14 and CD89 and consequently are downregulated for LPS- and IgA-mediated activities. J Immunol 167: 2651-2656.
-
(2001)
J Immunol
, vol.167
, pp. 2651-2656
-
-
Smith, P.D.1
Smythies, L.E.2
Mosteller-Barnum, M.3
-
170
-
-
69449105914
-
Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease
-
Smith AM, Rahman FZ, Hayee B et al (2009). Disordered macrophage cytokine secretion underlies impaired acute inflammation and bacterial clearance in Crohn's disease. J Exp Med 206: 1883-1897.
-
(2009)
J Exp Med
, vol.206
, pp. 1883-1897
-
-
Smith, A.M.1
Rahman, F.Z.2
Hayee, B.3
-
171
-
-
13744256812
-
Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity
-
Smythies LE, Sellers M, Clements RH et al (2005). Human intestinal macrophages display profound inflammatory anergy despite avid phagocytic and bacteriocidal activity. J Clin Invest 115: 66-75.
-
(2005)
J Clin Invest
, vol.115
, pp. 66-75
-
-
Smythies, L.E.1
Sellers, M.2
Clements, R.H.3
-
172
-
-
55949124035
-
Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients
-
Sokol H, Pigneur B, Watterlot R et al (2008). Faecalibacterium prausnitzii is an anti-inflammatory commensal bacterium identified by gut microbiota analysis of Crohn disease patients. Proc Natl Acad Sci USA 105: 16731-16736.
-
(2008)
Proc Natl Acad Sci USA
, vol.105
, pp. 16731-16736
-
-
Sokol, H.1
Pigneur, B.2
Watterlot, R.3
-
173
-
-
33144468326
-
European evidence based consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis
-
Stange EF, Travis SP, Vermeire S et al (2006). European evidence based consensus on the diagnosis and management of Crohn's disease: definitions and diagnosis. Gut 55(Suppl I): i1-i15.
-
(2006)
Gut
, vol.55
, Issue.SUPPL. I
-
-
Stange, E.F.1
Travis, S.P.2
Vermeire, S.3
-
174
-
-
38749106156
-
European evidence-based consensus on the diagnosis and management of ulcerative colitis: definitions and diagnosis
-
Stange EF, Travis SP, Vermeire S et al (2008). European evidence-based consensus on the diagnosis and management of ulcerative colitis: definitions and diagnosis. J Crohn's Colitis 2: 1-23.
-
(2008)
J Crohn's Colitis
, vol.2
, pp. 1-23
-
-
Stange, E.F.1
Travis, S.P.2
Vermeire, S.3
-
178
-
-
0346787909
-
Clinical practice: acute infectious diarrhoea
-
Thielman NM, Guerrant RL (2004). Clinical practice: acute infectious diarrhoea. N Engl J Med 350: 38-47.
-
(2004)
N Engl J Med
, vol.350
, pp. 38-47
-
-
Thielman, N.M.1
Guerrant, R.L.2
-
179
-
-
17044458998
-
Guidelines for the investigation of chronic diarrhoea, 2nd edition
-
Thomas PD, Forbes A, Green J et al (2003). Guidelines for the investigation of chronic diarrhoea, 2nd edition. Gut 52 (Suppl. 5): v1-v15.
-
(2003)
Gut
, vol.52
, Issue.SUPPL.. 5
-
-
Thomas, P.D.1
Forbes, A.2
Green, J.3
-
180
-
-
0242464926
-
CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes
-
Tiede I, Fritz G, Strand S et al (2003). CD28-dependent Rac1 activation is the molecular target of azathioprine in primary human CD4+ T lymphocytes. J Clin Invest 111: 1133-1145.
-
(2003)
J Clin Invest
, vol.111
, pp. 1133-1145
-
-
Tiede, I.1
Fritz, G.2
Strand, S.3
-
181
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
Travassos LH, Carneiro LA, Ramjeet M et al (2010). Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol 11: 55-62.
-
(2010)
Nat Immunol
, vol.11
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
-
182
-
-
33144459948
-
European evidence based consensus on the diagnosis and management of Crohn's disease: current management
-
Travis SPL, Stange EF, Lémann M et al (2006). European evidence based consensus on the diagnosis and management of Crohn's disease: current management. Gut 55(Suppl I): i16-i35.
-
(2006)
Gut
, vol.55
, Issue.SUPPL. I
-
-
Travis, S.P.L.1
Stange, E.F.2
Lémann, M.3
-
183
-
-
38749095183
-
European evidence-based Consensus on the management of ulcerative colitis: Current management
-
Travis SPL, Stange EF, Lémann M et al (2008). European evidence-based Consensus on the management of ulcerative colitis: Current management. J Crohn's Colitis 2: 24-62.
-
(2008)
J Crohn's Colitis
, vol.2
, pp. 24-62
-
-
Travis, S.P.L.1
Stange, E.F.2
Lémann, M.3
-
184
-
-
78650628082
-
Human RORγt+ TH17 cells preferentially differentiate from naive FOXP3+ Treg in the presence of lineage specific polarizing factors
-
Valmori D, Raffina C, Raimbaud I, Ayyoub M (2010). Human RORγt+ TH17 cells preferentially differentiate from naive FOXP3+ Treg in the presence of lineage specific polarizing factors. Proc Natl Acad Sci USA 107: 19402-19407.
-
(2010)
Proc Natl Acad Sci USA
, vol.107
, pp. 19402-19407
-
-
Valmori, D.1
Raffina, C.2
Raimbaud, I.3
Ayyoub, M.4
-
185
-
-
34147211616
-
Prediction of anti tumour necrosis factor clinical efficacy by real-time visualisation of apoptosis in patients with Crohn's disease
-
Van den Brande JM, Koehler TC, Zelinkova Z et al (2007). Prediction of anti tumour necrosis factor clinical efficacy by real-time visualisation of apoptosis in patients with Crohn's disease. Gut 56: 509-517.
-
(2007)
Gut
, vol.56
, pp. 509-517
-
-
Van den Brande, J.M.1
Koehler, T.C.2
Zelinkova, Z.3
-
186
-
-
21344446543
-
Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studies
-
Velayos FS, Terdiman JP, Walsh JM (2005). Effect of 5-aminosalicylate use on colorectal cancer and dysplasia risk: a systematic review and metaanalysis of observational studies. Am J Gastroenterol 100: 1345-1353.
-
(2005)
Am J Gastroenterol
, vol.100
, pp. 1345-1353
-
-
Velayos, F.S.1
Terdiman, J.P.2
Walsh, J.M.3
-
187
-
-
32244442562
-
TGF-beta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells
-
Veldhoen M, Hocking RJ, Atkins CJ, Locksley RM, Stockinger B (2006). TGF-beta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells. Immunity 24: 179-189.
-
(2006)
Immunity
, vol.24
, pp. 179-189
-
-
Veldhoen, M.1
Hocking, R.J.2
Atkins, C.J.3
Locksley, R.M.4
Stockinger, B.5
-
188
-
-
18444381172
-
CARD15 genetic variation in a Quebec population: prevalence, genotype-phenotype relationship, and haplotype structure
-
Vermeire S, Wild G, Kocher K et al (2002). CARD15 genetic variation in a Quebec population: prevalence, genotype-phenotype relationship, and haplotype structure. Am J Hum Genet 71: 74-83.
-
(2002)
Am J Hum Genet
, vol.71
, pp. 74-83
-
-
Vermeire, S.1
Wild, G.2
Kocher, K.3
-
189
-
-
78650114600
-
Colon cancer in inflammatory bowel disease: recent trends, questions and answers
-
Viennot S, Deleporte A, Moussata D, Nancey S, Flourié B, Reimund JM (2009). Colon cancer in inflammatory bowel disease: recent trends, questions and answers. Gastroenterol Clin Biol 33(Suppl 3): S190-S201.
-
(2009)
Gastroenterol Clin Biol
, vol.33
, Issue.SUPPL. 3
-
-
Viennot, S.1
Deleporte, A.2
Moussata, D.3
Nancey, S.4
Flourié, B.5
Reimund, J.M.6
-
190
-
-
65249108735
-
Autophagy genes in immunity
-
Virgin HW, Levine B (2009). Autophagy genes in immunity. Nat Immunol 10: 461-470.
-
(2009)
Nat Immunol
, vol.10
, pp. 461-470
-
-
Virgin, H.W.1
Levine, B.2
-
191
-
-
44049102724
-
A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)- 17 responses
-
Volpe E, Servant N, Zollinger R et al (2008). A critical function for transforming growth factor-beta, interleukin 23 and proinflammatory cytokines in driving and modulating human T(H)- 17 responses. Nat Immunol 9: 650-657.
-
(2008)
Nat Immunol
, vol.9
, pp. 650-657
-
-
Volpe, E.1
Servant, N.2
Zollinger, R.3
-
192
-
-
4444253690
-
NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses
-
Watanabe T, Kitani A, Murray PJ, Strober W (2004). NOD2 is a negative regulator of Toll-like receptor 2-mediated T helper type 1 responses. Nat Immunol 5: 800-808.
-
(2004)
Nat Immunol
, vol.5
, pp. 800-808
-
-
Watanabe, T.1
Kitani, A.2
Murray, P.J.3
Strober, W.4
-
193
-
-
61649123125
-
Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort
-
Weersma RK, Stokkers PCF, van Bodegraven AA et al (2009). Molecular prediction of disease risk and severity in a large Dutch Crohn's disease cohort. Gut 58: 388-395.
-
(2009)
Gut
, vol.58
, pp. 388-395
-
-
Weersma, R.K.1
Stokkers, P.C.F.2
van Bodegraven, A.A.3
-
194
-
-
84969213492
-
Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls
-
Wellcome Trust Case Control Consortium
-
Wellcome Trust Case Control Consortium (2007). Genome-wide association study of 14, 000 cases of seven common diseases and 3, 000 shared controls. Nature 447: 661-678.
-
(2007)
Nature
, vol.447
, pp. 661-678
-
-
-
195
-
-
34247271308
-
Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3
-
Williams LM, Rudensky AY (2007). Maintenance of the Foxp3-dependent developmental program in mature regulatory T cells requires continued expression of Foxp3. Nat Immunol 8: 277-284.
-
(2007)
Nat Immunol
, vol.8
, pp. 277-284
-
-
Williams, L.M.1
Rudensky, A.Y.2
-
196
-
-
33745288812
-
Emerging possibilities in the development and function of regulatory T cells
-
Wing K, Fehervari Z, Sakaguchi S (2006). Emerging possibilities in the development and function of regulatory T cells. Int Immunol 18: 991-1000.
-
(2006)
Int Immunol
, vol.18
, pp. 991-1000
-
-
Wing, K.1
Fehervari, Z.2
Sakaguchi, S.3
-
197
-
-
0345655293
-
Survival and cause-specific mortality in ulcerative colitis: follow-up of a population-based cohort in Copenhagen County
-
Winther KV, Jess T, Langholz E, Munkholm P, Binder V (2003). Survival and cause-specific mortality in ulcerative colitis: follow-up of a population-based cohort in Copenhagen County. Gastroenterology 125: 1576-1582.
-
(2003)
Gastroenterology
, vol.125
, pp. 1576-1582
-
-
Winther, K.V.1
Jess, T.2
Langholz, E.3
Munkholm, P.4
Binder, V.5
-
198
-
-
9944260628
-
Long-term risk of cancer in ulcerative colitis: a population-based cohort study from Copenhagen County
-
Winther KV, Jess T, Langholz E, Munkholm P, Binder V (2004). Long-term risk of cancer in ulcerative colitis: a population-based cohort study from Copenhagen County. Clin Gastroenterol Hepatol 2: 1088-1095.
-
(2004)
Clin Gastroenterol Hepatol
, vol.2
, pp. 1088-1095
-
-
Winther, K.V.1
Jess, T.2
Langholz, E.3
Munkholm, P.4
Binder, V.5
-
199
-
-
34249799285
-
Cutting edge: regulatory T cells induce CD4+ CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta
-
Xu L, Kitani A, Fuss I, Strober W (2007). Cutting edge: regulatory T cells induce CD4+ CD25-Foxp3- T cells or are self-induced to become Th17 cells in the absence of exogenous TGF-beta. J Immunol 178: 6725-6729.
-
(2007)
J Immunol
, vol.178
, pp. 6725-6729
-
-
Xu, L.1
Kitani, A.2
Fuss, I.3
Strober, W.4
-
200
-
-
0034193039
-
IL-6 is required for the development of TH1 cell-mediated murine colitis
-
Yamamoto M, Yoshizaki K, Kishimoto T, Ito H (2000). IL-6 is required for the development of TH1 cell-mediated murine colitis. J Immunol 164: 4878-4882.
-
(2000)
J Immunol
, vol.164
, pp. 4878-4882
-
-
Yamamoto, M.1
Yoshizaki, K.2
Kishimoto, T.3
Ito, H.4
-
201
-
-
53349120339
-
Commensal-dependent expression of IL-25 regulates the IL-23 - IL-17 axis in the intestine
-
Zaph C, Du Y, Saenz SA et al (2008). Commensal-dependent expression of IL-25 regulates the IL-23 - IL-17 axis in the intestine. J Exp Med 205: 2191-2198.
-
(2008)
J Exp Med
, vol.205
, pp. 2191-2198
-
-
Zaph, C.1
Du, Y.2
Saenz, S.A.3
-
202
-
-
65549098640
-
CD4 T-cell differentiation and inflammatory bowel disease
-
Zenewicz LA, Antov A, Flavell RA (2009). CD4 T-cell differentiation and inflammatory bowel disease. Trends Mol Med 15: 199-207.
-
(2009)
Trends Mol Med
, vol.15
, pp. 199-207
-
-
Zenewicz, L.A.1
Antov, A.2
Flavell, R.A.3
-
203
-
-
73849110167
-
Heterogeneity and plasticity of T helper cells
-
Zhu J, Paul WE (2010). Heterogeneity and plasticity of T helper cells. Cell Res 20: 4-12.
-
(2010)
Cell Res
, vol.20
, pp. 4-12
-
-
Zhu, J.1
Paul, W.E.2
|