The molecular classification of the clinical manifestations of Crohn's disease

Gastroenterology

Volumn 122, Issue 4, 2002, Pages 854-866

  Ahmad, Tariq ^a   Armuzzi, Alessandro ^a   Bunce, Mike ^a   MulcahyHawes, Kim ^a   Marshall, Sara E ^b   Orchard, Timothy R ^a   Crawshaw, Jonathan ^a   Large, Oliver ^a   De Silva, Arjuna ^a   Cook, Julia T ^a   Barnardo, Martin ^a   Cullen, Sue ^a   Welsh, Ken I ^c   Jewell, Derek P ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b IMPERIAL COLLEGE LONDON   (United Kingdom)

^c NATIONAL HEART AND LUNG INSTITUTE   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CASPASE RECRUITMENT DOMAIN PROTEIN 15; GENE PRODUCT; HLA ANTIGEN; UNCLASSIFIED DRUG;

ADOLESCENT; ADULT; AGED; ALLELE; ARTICLE; CHILD; CHROMOSOME 16; CONTROLLED STUDY; CROHN DISEASE; DIAGNOSTIC ACCURACY; DISEASE COURSE; FEMALE; FOLLOW UP; GENE LINKAGE DISEQUILIBRIUM; GENE MAPPING; GENE MUTATION; GENETIC ASSOCIATION; GENETIC POLYMORPHISM; GENETIC SUSCEPTIBILITY; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN TISSUE; ILEUM DISEASE; MAJOR CLINICAL STUDY; MALE; PHENOTYPE; PRIORITY JOURNAL; RISK FACTOR; UNITED KINGDOM;

EID: 0036202336     PISSN: 00165085     EISSN: None     Source Type: Journal    
DOI: 10.1053/gast.2002.32413     Document Type: Article

References (57)

1. Proposed classification of patient subgroups in Crohn's disease
2. A simple classification of Crohn's disease: Report of the working party for the world congress of gastroenterology, Vienna 1998
3. Crohn's disease: Influence of age at diagnosis on site and clinical type of disease
4. Clinical patterns of familial inflammatory bowel disease
5. Crohn's disease: Concordance for site and clinical type in affected family members - Potential hereditary influences
6. Clinical characteristics of Crohn's disease in 72 families
7. Clinical phenotype is related to HLA genotype in the peripheral arthropathies of inflammatory bowel disease
8. HLA-DRB1z.ast;03, but not the TNFα-308 promoter gene polymorphism, confers protection against fistulising Crohn's disease
9. Identification of novel susceptibility loci for inflammatory bowel disease on chromosomes 1p, 3q, and 4q: Evidence for epistasis between 1p and IBD1
10. Genome-wide search in Canadian families with inflammatory bowel disease reveals two novel susceptibility loci
11. Genetic variation in the 5q31 cytokine gene cluster confers susceptibility to Crohn disease
12. A genome-wide analysis provides evidence for novel linkages in inflammatory bowel disease in a large European cohort
13. Two-stage genome-wide search in inflammatory bowel disease provides evidence for susceptibility loci on chromosomes 3, 7 and 12
14. A genome wide search identifies potential new susceptibility loci for Crohn's disease
15. High-density genome scan in Crohn's disease shows confirmed linkage to Chromosome 14q11-12
16. Mapping of a susceptibility locus for Crohn's disease on chromosome 16
17. International collaboration provides convincing linkage replication in complex disease through analysis of a large pooled data set: Crohn's disease and chromosome 16
18. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
19. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
20. Association between insertion mutation in NOD2 gene and Crohn's disease in German and British populations
21. Nod2, a Nod1/Apaf-1 family member that is restricted to monocytes and activates NF-KB
22. Linkage of Crohn's disease to the major histocompatibility complex region is detected by multiple nonparametric analyses
23. Linkage of inflammatory bowel disease to human chromosome 6p
24. HLA Class II gene frequencies in Crohn's disease: A population based analysis in Germany
25. Association of HLA class II genes with susceptibility to Crohn's disease
26. HLA class II haplotype associations with inflammatory bowel disease in Jewish (Ashkenazi) and non-Jewish caucasian populations
27. HLA-DR and -DQ phenotypes in inflammatory bowel disease: A meta-analysis
28. Peripheral arthropathies in inflammatory bowel disease: Their articular distribution and natural history
29. Costs and cost effectiveness of health checks conducted by nurses in primary care: The Oxcheck study
30. Molecular typing for the MHC with PCR-SSP
31. MICA sequences 2000
32. Characterization of the human central MHC gene, BAT1: Genomic structure and expression
33. Haplotypic single nucleotide polymorphism in the central MHC gene IKBL, a potential regulator of NF-κB function
34. The central MHC gene IKBL carries a structural polymorphism that is associated with HLA-A3, B7, DR15
35. Polymerase chain reaction haplotyping using 3′ mismatches in the forward and reverse primers: Application to the biallelic polymorphisms of tumour necrosis factor and lymphotoxin alpha
36. An alleleic polymorphism within the human tumour necrosis factor alpha gene detectable by Ncol restriction of PCR product
37. Polymorphism of the 5′-flanking region of the human tumour necrosis factor (TNF)-alpha gene in Japanese
38. Single-nucleotide polymorphism detection by denaturating high-performance fiquid chromatography and direct sequencing in genes in the MHC class III region encoding novel cell surface molecules
39. Structure and expression of the three MHC-linked HSP70 genes
40. Gene and haplotype frequencies of HLA antigens in 269 patients with Crohn's disease
41. An increased risk of Crohn's disease in individuals who inherit the HLA class II DRB3z.ast;0301 allele
42. Behaviour of Crohn's disease according to the Vienna classification: Changing pattern over the course of the disease
43. Linkage heterogeneity for the IBD1 locus in Crohn's disease pedigrees by disease onset and severity
44. Allele-specific binding of the ubiquitous transcription factor OCT-1 to the functional single nucleotide polymorphism (SNP) sites in the tumour necrosis factor-alpha gene (TNFA) promoter
45. The genetic basis for the association of the B8.1 ancestral haplotype
46. The central MHC gene, BAT1, may encode a protein that down-regulates cytokine production
47. Recognition of stress-induced MHC molecules by intestinal epithelial gamma delta T cells
48. A single amino acid substitution causes loss of expression of a MICA allele
49. Crohn's disease is associated with novel polymorphisms in the 5′ flanking region of the tumour necrosis gene
50. Contribution of genes of the major histocompatibility complex to susceptibility and disease phenotype in inflammatory bowel disease
51. Genetic markers may predict disease behaviour in patients with ulcerative colitis
52. Activation of nuclear factor kB in inflammatory bowel disease
53. HLA molecules, bacteria and autoimmunity
54. CD4 T cells reactive to enteric bacterial antigens in spontaneously colitic C3H/HeJBir mice: Increased T helper type 1 response and ability to transfer disease
55. Regulatory interactions between CD-45R B high and CD45R Blow CD4+ T cells are important for the balance between protective and pathogenic cell-mediated immunity
56. The new genetics in clinical practice