메뉴 건너뛰기




Volumn 4, Issue 1, 2011, Pages 16-30

Nucleotide-binding oligomerization domain-like receptors and inflammasomes in the pathogenesis of non-microbial inflammation and diseases

Author keywords

Chronic disease; Inflammasome; Non microbial inflammation; Nucleotide binding oligomerization domain like receptor

Indexed keywords

CRYOPYRIN; INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA; MULTIPROTEIN COMPLEX; NUCLEOTIDE BINDING OLIGOMERIZATION DOMAIN LIKE RECEPTOR;

EID: 83555176154     PISSN: 1662811X     EISSN: 16628128     Source Type: Journal    
DOI: 10.1159/000334247     Document Type: Review
Times cited : (91)

References (104)
  • 2
    • 77950362382 scopus 로고    scopus 로고
    • The inflammasomes
    • Schroder K, Tschopp J: The inflammasomes. Cell 2010; 140: 821-832.
    • (2010) Cell , vol.140 , pp. 821-832
    • Schroder, K.1    Tschopp, J.2
  • 3
    • 0036671894 scopus 로고    scopus 로고
    • The Inflammasome: A molecular platform triggering activation of inflammatory caspases and processing of proIL-β
    • DOI 10.1016/S1097-2765(02)00599-3
    • Martinon F, Burns K, Tschopp J: The inflammasome: a molecular platform triggering activation of inflammatory caspases and processing of proIL-beta. Mol Cell 2002; 10: 417-426. (Pubitemid 35007355)
    • (2002) Molecular Cell , vol.10 , Issue.2 , pp. 417-426
    • Martinon, F.1    Burns, K.2    Tschopp, J.3
  • 6
    • 39749084641 scopus 로고    scopus 로고
    • Active Caspase-1 Is a Regulator of Unconventional Protein Secretion
    • DOI 10.1016/j.cell.2007.12.040, PII S0092867408001116
    • Keller M, Ruegg A, Werner S, Beer HD: Active caspase-1 is a regulator of unconventional protein secretion. Cell 2008; 132: 818-831. (Pubitemid 351312798)
    • (2008) Cell , vol.132 , Issue.5 , pp. 818-831
    • Keller, M.1    Ruegg, A.2    Werner, S.3    Beer, H.-D.4
  • 8
    • 68149100523 scopus 로고    scopus 로고
    • NLRP3 (NALP3, cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways
    • Willingham SB, Allen IC, Bergstralh DT, Brickey WJ, Huang MT, Taxman DJ, Duncan JA, Ting JP: NLRP3 (NALP3, cryopyrin) facilitates in vivo caspase-1 activation, necrosis, and HMGB1 release via inflammasome-dependent and -independent pathways. J Immunol 2009; 183: 2008-2015.
    • (2009) J Immunol , vol.183 , pp. 2008-2015
    • Willingham, S.B.1    Allen, I.C.2    Bergstralh, D.T.3    Brickey, W.J.4    Huang, M.T.5    Taxman, D.J.6    Duncan, J.A.7    Ting, J.P.8
  • 9
    • 37549002511 scopus 로고    scopus 로고
    • The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock
    • Shao W, Yeretssian G, Doiron K, Hussain SN, Saleh M: The caspase-1 digestome identifies the glycolysis pathway as a target during infection and septic shock. J Biol Chem 2007; 282: 36321-36329.
    • (2007) J Biol Chem , vol.282 , pp. 36321-36329
    • Shao, W.1    Yeretssian, G.2    Doiron, K.3    Hussain, S.N.4    Saleh, M.5
  • 11
    • 75649096002 scopus 로고    scopus 로고
    • Thioredoxin-interacting protein links oxidative stress to inflammasome activation
    • Zhou R, Tardivel A, Thorens B, Choi I, Tschopp J: Thioredoxin-interacting protein links oxidative stress to inflammasome activation. Nat Immunol 2010; 11: 136-140.
    • (2010) Nat Immunol , vol.11 , pp. 136-140
    • Zhou, R.1    Tardivel, A.2    Thorens, B.3    Choi, I.4    Tschopp, J.5
  • 12
    • 78651393239 scopus 로고    scopus 로고
    • A role for mitochondria in NLRP3 inflammasome activation
    • Zhou R, Yazdi AS, Menu P, Tschopp J: A role for mitochondria in NLRP3 inflammasome activation. Nature 2011; 469: 221-225.
    • (2011) Nature , vol.469 , pp. 221-225
    • Zhou, R.1    Yazdi, A.S.2    Menu, P.3    Tschopp, J.4
  • 14
    • 34247118826 scopus 로고    scopus 로고
    • Pannexin-1-Mediated Recognition of Bacterial Molecules Activates the Cryopyrin Inflammasome Independent of Toll-like Receptor Signaling
    • DOI 10.1016/j.immuni.2007.03.008, PII S1074761307002117
    • Kanneganti TD, Lamkanfi M, Kim YG, Chen G, Park JH, Franchi L, Vandenabeele P, Nunez G: Pannexin-1-mediated recognition of bacterial molecules activates the cryopyrin inflammasome independent of Toll-like receptor signaling. Immunity 2007; 26: 433-443. (Pubitemid 46603000)
    • (2007) Immunity , vol.26 , Issue.4 , pp. 433-443
    • Kanneganti, T.-D.1    Lamkanfi, M.2    Kim, Y.-G.3    Chen, G.4    Park, J.-H.5    Franchi, L.6    Vandenabeele, P.7    Nunez, G.8
  • 15
    • 10644258637 scopus 로고    scopus 로고
    • PAN1/ NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-κB and caspase-1 activation in macrophages
    • DOI 10.1074/jbc.M406741200
    • Bruey JM, Bruey-Sedano N, Newman R, Chandler S, Stehlik C, Reed JC: PAN1/ NALP2/PYPAF2, an inducible inflammatory mediator that regulates NF-kappaB and caspase-1 activation in macrophages. J Biol Chem 2004; 279: 51897-51907. (Pubitemid 39656557)
    • (2004) Journal of Biological Chemistry , vol.279 , Issue.50 , pp. 51897-51907
    • Bruey, J.M.1    Bruey-Sedano, N.2    Newman, R.3    Chandler, S.4    Stehlik, C.5    Reed, J.C.6
  • 16
    • 0037144586 scopus 로고    scopus 로고
    • A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta
    • Fiorentino L, Stehlik C, Oliveira V, Ariza ME, Godzik A, Reed JC: A novel PAAD-containing protein that modulates NF-kappa B induction by cytokines tumor necrosis factor-alpha and interleukin-1beta. J Biol Chem 2002; 277: 35333-35340.
    • (2002) J Biol Chem , vol.277 , pp. 35333-35340
    • Fiorentino, L.1    Stehlik, C.2    Oliveira, V.3    Ariza, M.E.4    Godzik, A.5    Reed, J.C.6
  • 21
    • 20444442787 scopus 로고    scopus 로고
    • PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1β secretion
    • DOI 10.1074/jbc.M410057200
    • Kinoshita T, Wang Y, Hasegawa M, Imamura R, Suda T: PYPAF3, a PYRIN-containing APAF-1-like protein, is a feedback regulator of caspase-1-dependent interleukin-1beta secretion. J Biol Chem 2005; 280: 21720-21725. (Pubitemid 40827818)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.23 , pp. 21720-21725
    • Kinoshita, T.1    Wang, Y.2    Hasegawa, M.3    Imamura, R.4    Suda, T.5
  • 25
    • 0037852184 scopus 로고    scopus 로고
    • Cutting edge: Monarch-1: A pyrin/nucleotide-binding domain/leucine-rich repeat protein that controls classical and nonclassical MHC class I genes
    • Williams KL, Taxman DJ, Linhoff MW, Reed W, Ting JP: Cutting edge: monarch-1: a pyrin/nucleotide-binding domain/leucinerich repeat protein that controls classical and nonclassical MHC class I genes. J Immunol 2003; 170: 5354-5358. (Pubitemid 36617819)
    • (2003) Journal of Immunology , vol.170 , Issue.11 , pp. 5354-5358
    • Williams, K.L.1    Taxman, D.J.2    Linhoff, M.W.3    Reed, W.4    Ting, J.P.-Y.5
  • 26
    • 79251588741 scopus 로고    scopus 로고
    • NLRP4 negatively regulates autophagic processes through an association with beclin1
    • Jounai N, Kobiyama K, Shiina M, Ogata K, Ishii KJ, Takeshita F: NLRP4 negatively regulates autophagic processes through an association with beclin1. J Immunol 2011; 186: 1646-1655.
    • (2011) J Immunol , vol.186 , pp. 1646-1655
    • Jounai, N.1    Kobiyama, K.2    Shiina, M.3    Ogata, K.4    Ishii, K.J.5    Takeshita, F.6
  • 30
    • 0035179970 scopus 로고    scopus 로고
    • Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome
    • DOI 10.1038/ng756
    • Hoffman HM, Mueller JL, Broide DH, Wanderer AA, Kolodner RD: Mutation of a new gene encoding a putative pyrin-like protein causes familial cold autoinflammatory syndrome and Muckle-Wells syndrome. Nat Genet 2001; 29: 301-305. (Pubitemid 33096455)
    • (2001) Nature Genetics , vol.29 , Issue.3 , pp. 301-305
    • Hoffman, H.M.1    Mueller, J.L.2    Broide, D.H.3    Wanderer, A.A.4    Kolodner, R.D.5
  • 32
    • 66949175347 scopus 로고    scopus 로고
    • A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses
    • Meng G, Zhang F, Fuss I, Kitani A, Strober W: A mutation in the Nlrp3 gene causing inflammasome hyperactivation potentiates Th17 cell-dominant immune responses. Immunity 2009; 30: 860-874.
    • (2009) Immunity , vol.30 , pp. 860-874
    • Meng, G.1    Zhang, F.2    Fuss, I.3    Kitani, A.4    Strober, W.5
  • 33
    • 32944468985 scopus 로고    scopus 로고
    • Gout-associated uric acid crystals activate the NALP3 inflammasome
    • DOI 10.1038/nature04516, PII N04516
    • Martinon F, Petrilli V, Mayor A, Tardivel A, Tschopp J: Gout-associated uric acid crystals activate the NALP3 inflammasome. Nature 2006; 440: 237-241. (Pubitemid 43372104)
    • (2006) Nature , vol.440 , Issue.7081 , pp. 237-241
    • Martinon, F.1    Petrilli, V.2    Mayor, A.3    Tardivel, A.4    Tschopp, J.5
  • 36
    • 43049159804 scopus 로고    scopus 로고
    • Genetic variation in proteins of the cryopyrin inflammasome influences susceptibility and severity of rheumatoid arthritis (the Swedish TIRA project)
    • Kastbom A, Verma D, Eriksson P, Skogh T, Wingren G, Soderkvist P: Genetic variation in proteins of the cryopyrin inflammasome influences susceptibility and severity of rheumatoid arthritis (the Swedish TIRA project). Rheumatology 2008; 47: 415-417.
    • (2008) Rheumatology , vol.47 , pp. 415-417
    • Kastbom, A.1    Verma, D.2    Eriksson, P.3    Skogh, T.4    Wingren, G.5    Soderkvist, P.6
  • 37
    • 56449100492 scopus 로고    scopus 로고
    • SNP-guided microRNA maps (MirMaps) of 16 common human disorders identify a clinically accessible therapy reversing transcriptional aberrations of nuclear import and inflammasome pathways
    • Glinsky GV: SNP-guided microRNA maps (MirMaps) of 16 common human disorders identify a clinically accessible therapy reversing transcriptional aberrations of nuclear import and inflammasome pathways. Cell Cycle 2008; 7: 3564-3576.
    • (2008) Cell Cycle , vol.7 , pp. 3564-3576
    • Glinsky, G.V.1
  • 38
    • 73949092133 scopus 로고    scopus 로고
    • Expression and function of the NALP3 inflammasome in rheumatoid synovium
    • Kolly L, Busso N, Palmer G, Talabot-Ayer D, Chobaz V, So A: Expression and function of the NALP3 inflammasome in rheumatoid synovium. Immunology 2010; 129: 178-185.
    • (2010) Immunology , vol.129 , pp. 178-185
    • Kolly, L.1    Busso, N.2    Palmer, G.3    Talabot-Ayer, D.4    Chobaz, V.5    So, A.6
  • 39
    • 17644375193 scopus 로고    scopus 로고
    • Expression and regulation of cryopyrin and related proteins in rheumatoid arthritis synovium
    • DOI 10.1136/ard.2004.025577
    • Rosengren S, Hoffman HM, Bugbee W, Boyle DL: Expression and regulation of cryopyrin and related proteins in rheumatoid arthritis synovium. Ann Rheum Dis 2005; 64: 708-714. (Pubitemid 40559297)
    • (2005) Annals of the Rheumatic Diseases , vol.64 , Issue.5 , pp. 708-714
    • Rosengren, S.1    Hoffman, H.M.2    Bugbee, W.3    Boyle, D.L.4
  • 40
    • 33846079219 scopus 로고    scopus 로고
    • The comparative efficacy and safety of biologics for the treatment of rheumatoid arthritis: A systematic review and metaanalysis
    • Gartlehner G, Hansen RA, Jonas BL, Thieda P, Lohr KN: The comparative efficacy and safety of biologics for the treatment of rheumatoid arthritis: a systematic review and metaanalysis. J Rheumatol 2006; 33: 2398-2408. (Pubitemid 46067817)
    • (2006) Journal of Rheumatology , vol.33 , Issue.12 , pp. 2398-2408
    • Gartlehner, G.1    Hansen, R.A.2    Jonas, B.L.3    Thieda, P.4    Lohr, K.N.5
  • 44
    • 57749209136 scopus 로고    scopus 로고
    • Inhibition of human DNA polymerase beta activity by the anticancer prodrug Cloretazine
    • Frederick AM, Davis ML, Rice KP: Inhibition of human DNA polymerase beta activity by the anticancer prodrug Cloretazine. Biochem Biophys Res Commun 2009; 378: 419-423.
    • (2009) Biochem Biophys Res Commun , vol.378 , pp. 419-423
    • Frederick, A.M.1    Davis, M.L.2    Rice, K.P.3
  • 46
    • 0037336851 scopus 로고    scopus 로고
    • Caspase gene expression in the brain as a function of the clinical progression of Alzheimer disease
    • DOI 10.1001/archneur.60.3.369
    • Pompl PN, Yemul S, Xiang Z, Ho L, Haroutunian V, Purohit D, Mohs R, Pasinetti GM: Caspase gene expression in the brain as a function of the clinical progression of Alzheimer disease. Arch Neurol 2003; 60: 369-376. (Pubitemid 36314362)
    • (2003) Archives of Neurology , vol.60 , Issue.3 , pp. 369-376
    • Pompl, P.N.1    Yemul, S.2    Xiang, Z.3    Ho, L.4    Haroutunian, V.5    Purohit, D.6    Mohs, R.7    Pasinetti, G.M.8
  • 48
    • 4444254434 scopus 로고    scopus 로고
    • Increased expression of capase-1 and interleukin-18 in peripheral blood mononuclear cells in patients with multiple sclerosis
    • DOI 10.1191/1352458504ms1071oa
    • Huang WX, Huang P, Hillert J: Increased expression of caspase-1 and interleukin-18 in peripheral blood mononuclear cells in patients with multiple sclerosis. Mult Scler 2004; 10: 482-487. (Pubitemid 39207218)
    • (2004) Multiple Sclerosis , vol.10 , Issue.5 , pp. 482-487
    • Huang, W.-X.1    Huang, P.2    Hillert, J.3
  • 49
    • 77955475968 scopus 로고    scopus 로고
    • NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses
    • Gris D, Ye Z, Iocca HA, Wen H, Craven RR, Gris P, Huang M, Schneider M, Miller SD, Ting JP: NLRP3 plays a critical role in the development of experimental autoimmune encephalomyelitis by mediating Th1 and Th17 responses. J Immunol 2010; 185: 974-981.
    • (2010) J Immunol , vol.185 , pp. 974-981
    • Gris, D.1    Ye, Z.2    Iocca, H.A.3    Wen, H.4    Craven, R.R.5    Gris, P.6    Huang, M.7    Schneider, M.8    Miller, S.D.9    Ting, J.P.10
  • 50
    • 77954478334 scopus 로고    scopus 로고
    • Cutting edge: Critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis
    • Shaw PJ, Lukens JR, Burns S, Chi H, McGargill MA, Kanneganti TD: Cutting edge: critical role for PYCARD/ASC in the development of experimental autoimmune encephalomyelitis. J Immunol 2010; 184: 4610-4614.
    • (2010) J Immunol , vol.184 , pp. 4610-4614
    • Shaw, P.J.1    Lukens, J.R.2    Burns, S.3    Chi, H.4    McGargill, M.A.5    Kanneganti, T.D.6
  • 53
    • 33947203625 scopus 로고    scopus 로고
    • Differential regulation of inhibitors of apoptosis proteins in Alzheimer's disease brains
    • DOI 10.1016/j.nbd.2006.12.017, PII S0969996106003202
    • Christie LA, Su JH, Tu CH, Dick MC, Zhou J, Cotman CW: Differential regulation of inhibitors of apoptosis proteins in Alzheimer's disease brains. Neurobiol Dis 2007; 26: 165-173. (Pubitemid 46436496)
    • (2007) Neurobiology of Disease , vol.26 , Issue.1 , pp. 165-173
    • Christie, L.-A.1    Su, J.H.2    Tu, C.H.3    Dick, M.C.4    Zhou, J.5    Cotman, C.W.6
  • 55
    • 79953161325 scopus 로고    scopus 로고
    • Integrity of ATP binding site is essential for effective inhibition of the intrinsic apoptosis pathway by NAIP
    • Karimpour S, Davoodi J, Ghahremani MH: Integrity of ATP binding site is essential for effective inhibition of the intrinsic apoptosis pathway by NAIP. Biochem Biophys Res Commun 2011; 407: 158-162.
    • (2011) Biochem Biophys Res Commun , vol.407 , pp. 158-162
    • Karimpour, S.1    Davoodi, J.2    Ghahremani, M.H.3
  • 58
  • 59
    • 79951669207 scopus 로고    scopus 로고
    • The immune system in atherosclerosis
    • Hansson GK, Hermansson A: The immune system in atherosclerosis. Nat Immunol 2011; 12: 204-212.
    • (2011) Nat Immunol , vol.12 , pp. 204-212
    • Hansson, G.K.1    Hermansson, A.2
  • 62
    • 47849120473 scopus 로고    scopus 로고
    • Superoxide dismutase 1 regulates caspase-1 and endotoxic shock
    • Meissner F, Molawi K, Zychlinsky A: Superoxide dismutase 1 regulates caspase-1 and endotoxic shock. Nat Immunol 2008; 9: 866-872.
    • (2008) Nat Immunol , vol.9 , pp. 866-872
    • Meissner, F.1    Molawi, K.2    Zychlinsky, A.3
  • 63
    • 70249117528 scopus 로고    scopus 로고
    • Pathogen-induced interleukin-1beta processing and secretion is regulated by a biphasic redox response
    • Tassi S, Carta S, Vene R, Delfino L, Ciriolo MR, Rubartelli A: Pathogen-induced interleukin-1beta processing and secretion is regulated by a biphasic redox response. J Immunol 2009; 183: 1456-1462.
    • (2009) J Immunol , vol.183 , pp. 1456-1462
    • Tassi, S.1    Carta, S.2    Vene, R.3    Delfino, L.4    Ciriolo, M.R.5    Rubartelli, A.6
  • 64
    • 79953046719 scopus 로고    scopus 로고
    • The inflammasome NLRs in immunity, inflammation, and associated diseases
    • Davis BK, Wen H, Ting JP: The inflammasome NLRs in immunity, inflammation, and associated diseases. Ann Rev Immunol 2011; 29: 707-735.
    • (2011) Ann Rev Immunol , vol.29 , pp. 707-735
    • Davis, B.K.1    Wen, H.2    Ting, J.P.3
  • 71
    • 43249125839 scopus 로고    scopus 로고
    • Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica
    • DOI 10.1126/science.1156995
    • Dostert C, Petrilli V, Van Bruggen R, Steele C, Mossman BT, Tschopp J: Innate immune activation through Nalp3 inflammasome sensing of asbestos and silica. Science 2008; 320: 674-677. (Pubitemid 351928351)
    • (2008) Science , vol.320 , Issue.5876 , pp. 674-677
    • Dostert, C.1    Petrilli, V.2    Van Bruggen, R.3    Steele, C.4    Mossman, B.T.5    Tschopp, J.6
  • 73
    • 78650610580 scopus 로고    scopus 로고
    • Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1beta
    • Yazdi AS, Guarda G, Riteau N, Drexler SK, Tardivel A, Couillin I, Tschopp J: Nanoparticles activate the NLR pyrin domain containing 3 (Nlrp3) inflammasome and cause pulmonary inflammation through release of IL-1alpha and IL-1beta. Proc Natl Acad Sci USA 2010; 107: 19449-19454.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 19449-19454
    • Yazdi, A.S.1    Guarda, G.2    Riteau, N.3    Drexler, S.K.4    Tardivel, A.5    Couillin, I.6    Tschopp, J.7
  • 83
    • 79959573042 scopus 로고    scopus 로고
    • Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells
    • Csak T, Ganz M, Pespisa J, Kodys K, Dolganiuc A, Szabo G: Fatty acid and endotoxin activate inflammasomes in mouse hepatocytes that release danger signals to stimulate immune cells. Hepatology 2011; 54: 133-144.
    • (2011) Hepatology , vol.54 , pp. 133-144
    • Csak, T.1    Ganz, M.2    Pespisa, J.3    Kodys, K.4    Dolganiuc, A.5    Szabo, G.6
  • 86
  • 96
    • 77950002937 scopus 로고    scopus 로고
    • The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis
    • Zaki MH, Boyd KL, Vogel P, Kastan MB, Lamkanfi M, Kanneganti TD: The NLRP3 inflammasome protects against loss of epithelial integrity and mortality during experimental colitis. Immunity 2010; 32: 379-391.
    • (2010) Immunity , vol.32 , pp. 379-391
    • Zaki, M.H.1    Boyd, K.L.2    Vogel, P.3    Kastan, M.B.4    Lamkanfi, M.5    Kanneganti, T.D.6
  • 98
    • 79959540809 scopus 로고    scopus 로고
    • A functional role for Nlrp6 in intestinal inflammation and tumorigenesis
    • Chen GY, Liu M, Wang F, Bertin J, Nunez G: A functional role for Nlrp6 in intestinal inflammation and tumorigenesis. J Immunol 2011; 186: 7187-7194.
    • (2011) J Immunol , vol.186 , pp. 7187-7194
    • Chen, G.Y.1    Liu, M.2    Wang, F.3    Bertin, J.4    Nunez, G.5
  • 99
    • 77958088176 scopus 로고    scopus 로고
    • Genetic association of NALP1 with generalized vitiligo in Jordanian Arabs
    • Alkhateeb A, Qarqaz F: Genetic association of NALP1 with generalized vitiligo in Jordanian Arabs. Arch Dermatol Res 2010; 302: 631-634.
    • (2010) Arch Dermatol Res , vol.302 , pp. 631-634
    • Alkhateeb, A.1    Qarqaz, F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.