Nitric oxide induces thymocyte apoptosis via a caspase-1-dependent mechanism

Journal of Immunology

Volumn 165, Issue 3, 2000, Pages 1252-1258

  Zhou, Xin ^a   Gordon, Sherilyn A ^a   Kim, Young Myeong ^a,b   Hoffman, Rosemary A ^a   Chen, Yue ^a   Zhang, Xiao Ru ^a   Simmons, Richard L ^a   Ford, Henri R ^a  

^a CHILDREN S HOSPITAL OF PITTSBURGH   (United States)

^b Kangwon National University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

DNA FRAGMENT; INTERLEUKIN 1BETA CONVERTING ENZYME; NITRIC OXIDE; PROTEIN P53;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL CULTURE; DNA CLEAVAGE; ENZYME ACTIVITY; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; THYMOCYTE;

EID: 0034254290     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: 10.4049/jimmunol.165.3.1252     Document Type: Article

References (29)

1. Albina, J. E., S. Cui, R. B. Mateo, and J. S. Reichner. 1993. Nitric oxide-mediated apoptosis in murine peritoneal macrophages. J. Immunol. 150:5080.
2. Lu, L., C. A. Bonham, F. G. Chambers, S. C. Walkins, R. A. Hoffman, R. L. Simmons, and A. W. Thomson. 1996. Induction of nitric oxide synthase in mouse dendritic cells by TFN-γ, endotoxin, and interaction with allogeneic T cells: nitric oxide production is associated with dendritic cell apoptosis. J. Immunol. 157:3577.
3. Fehsel, K., K. D. Kroncke, K. L. Meyer, H. Huber, V. Wahn, and V. Kolb-Bachofen. 1995. Nitric oxide induces apoptosis in mouse thymocytes. J. Immunol. 155:2858.
4. Heneka, M. T., P. A. Loschmann, M. Gleichmann, M. Weller, J. B. Schulz, U. Wullner, and T. Klockgether. 1998. Induction of nitric oxide synthase and nitric oxide-mediated apoptosis in neuronal PC12 cells after stimulation with tumor necrosis factor-α/lipopolysaccharide. J. Neurochem. 71:88.
5. Tai, X. G., K. Toyo-oka, N. Yamamoto, Y. Yashiro, J. Mu, T. Hamaoka, and H. Fujiwara. 1997. Expression of an inducible type of nitric oxide (NO) synthase in the thymus and involvement of NO in deletion of TCR-stimulated double-positive thymocytes. J. Immunol. 158:4696.
6. Anderson, G., N. C. Moore, J. J. Owen, and E. J. Jenkinson. 1996. Cellular interactions in thymocyte development. Annu. Rev. Immunol. 14:73.
7. Lerner, A., L. K. Clayton, E. Mizoguchi, Y. Ghendler, W. van Ewijk, S. Koyasu, A. K. Bhan, and E. L. Reinherz. 1996. Cross-linking of T-cell receptors on double-positive thymocytes induces a cytokine-mediated stromal activation process linked to cell death. EMBO J. 15:5876.
8. Virag, L., G. S. Scott, S. Cuzzocrea, D. Marmer, A. L. Salzman, and C. Szabo. 1998. Peroxynitrite-induced thymocyte apoptosis: the role of caspases and poly (ADP-ribose) synthetase (PARS) activation. Immunology 94:345.
9. Cohen, G. M. 1997. Caspases: the executioners of apoptosis. Biochem. J. 326:1.
10. Thornberry, N. A., and Y. Lazebnik. 1998. Caspases: enemies within. Science 281:1312.
11. Yuan, J., S. Shaham, S. Ledoux, H. M. Ellis, and H. R. Horvitz. 1993. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1β-converting enzyme. Cell 75:641.
12. Thornberry, N. A., H. G. Bull, J. R. Calaycay, K. T. Chapman, A. D. Howard, M. J. Kostura, D. K. Miller, S. M. Molineaux, J. R. Weidner, J. Aunins, et al. 1992. A novel heterodimeric cysteine protease is required for interleukin-1β processing in monocytes. Nature 356:768.
13. Cerretti, D. P., C. J. Kozlosky, B. Mosley, N. Nelson, K. Van Ness, T. A. Greenstreet, C. J. March, S. R. Kronheim, T. Druck, L. A. Cannizzaro, et al. 1992. Molecular cloning of the interleukin-1β converting enzyme. Science 256:97.
14. Enari, M., H. Hug, and S. Nagata. 1995. Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 375:78.
15. Los, M., M. Van de Craen, L. C. Penning, H. Schenk, M. Westendorp, P. A. Baeuerle, W. Droge, P. H. Krammer, W. Fiers, and K. Schulze-Osthoff. 1995. Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature 375:81.
16. Hersh, D., D. M. Monack, M. R. Smith, N. Ghori, S. Falkow, and A. Zychlinsky. 1999. The Salmonella invasin SipB induces macrophage apoptosis by binding to caspase-1. Proc. Natl. Acad. Sci. USA 96:2396.
17. Hilbi, H., J. E. Moss, D. Hersh, Y. Chen, J. Arondel, S. Banerjee, R. A. Flavell, J. Yuan, P. J. Sansonetti, and A. Zychlinsky. 1998. Shigella-induced apoptosis is dependent on caspase-1 which binds to IpaB. J. Biol. Chem. 273:32895.
18. de Murcia, G., V. Schreiber, M. Molinete, B. Saulier, O. Poch, M. Masson, C. Niedergang, and J. Menissier de Murcia. 1994. Structure and function of poly(ADP-ribose) polymerase. Mol. Cell. Biochem. 138:15.
19. Tewari, M., L. T. Quan, K. O'Rourke, S. Desnoyers, Z. Zeng, D. R. Beidler, G. G. Poirier, G. S. Salvesen, and V. M. Dixit. 1995. Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase. Cell 81:801.
20. Tang, D., and V. J. Kidd. 1998. Cleavage of DFF-45/ICAD by multiple caspases is essential for its function during apoptosis. J. Biol. Chem. 273:28549.
21. Enari, M., H. Sakahira, H. Yokoyama, K. Okawa, A. Iwamatsu, and S. Nagata. 1998. A caspase-activated DNase that degrades DNA during apoptosis, and its inhibitor ICAD. [Published erratum appears in 1998 Nature 28:393]. Nature 391: 43.
22. Sakahira, H., M. Enari, and S. Nagata. 1998. Cleavage of CAD inhibitor in CAD activation and DNA degradation during apoptosis. Nature 391:96.
23. Hortelano, S., B. Dallaporta, N. Zamzami, T. Hirsch, S. A. Susin, I. Marzo, L. Bosca, and G. Kroemer. 1997. Nitric oxide induces apoptosis via triggering mitochondrial permeability transition. FEBS Lett. 410:373.
24. Kim, Y. M., R. V. Talanian, and T. R. Billiar. 1997. Nitric oxide inhibits apoptosis by preventing increases in caspase-3-like activity via two distinct mechanisms. J. Biol. Chem. 272:31138.
25. Kim, Y. M., R. V. Talanian, J. Li, and T. R. Billiar. 1998. Nitric oxide prevents IL-1β and IFN-γ-inducing factor (IL-18) release from macrophages by inhibiting caspase-1 (IL-1β-converting enzyme). J. Immunol. 161:4122.
26. McCarthy, S. A., R. N. Cacchione, M. S. Mainwaring, and J. S. Cairns. 1992. The effects of immunosuppressive drugs on the regulation of activation-induced apoptotic cell death in thymocytes. Transplantation 54:543.
27. Gu, Y., C. Samecki, R. A. Aldape, D. J. Livingston, and M. S. Su. 1995. Cleavage of poly(ADP-ribose) polymerase by interleukin-1β converting enzyme and its homologs TX and Nedd-2. J. Biol. Chem. 270:18715.
28. Li, J., T. R. Billiar, R. V. Talanian, and Y. M. Kim. 1997. Nitric oxide reversibly inhibits seven members of the caspase family via S-nitrosylation. Biochem. Biophys. Res. Commun. 240:419.
29. Mannick, J. B., A. Hausladen, L. Liu, D. T. Hess, M. Zeng, Q. X. Miao, L. S. Kane, A. J. Gow, and J. S. Stamler. 1999. Fas-induced caspase denitrosylation. Science 284:651.